{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T23:40:25Z","timestamp":1790206825804,"version":"4.1.0"},"reference-count":45,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2014,11,18]],"date-time":"2014-11-18T00:00:00Z","timestamp":1416268800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Gastroenterol"],"published-print":{"date-parts":[[2015,3]]},"DOI":"10.1007\/s00535-014-1015-2","type":"journal-article","created":{"date-parts":[[2014,11,21]],"date-time":"2014-11-21T06:14:36Z","timestamp":1416550476000},"page":"273-279","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":74,"title":["Pancreaticobiliary maljunction and biliary cancer"],"prefix":"10.1007","volume":"50","author":[{"given":"Terumi","family":"Kamisawa","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sawako","family":"Kuruma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Taku","family":"Tabata","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kazuro","family":"Chiba","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susumu","family":"Iwasaki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Satomi","family":"Koizumi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masanao","family":"Kurata","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Goro","family":"Honda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takao","family":"Itoi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2014,11,18]]},"reference":[{"key":"1015_CR1","doi-asserted-by":"crossref","first-page":"S84","DOI":"10.1016\/j.cgh.2009.08.024","volume":"7","author":"T Kamisawa","year":"2009","unstructured":"Kamisawa T, Takuma K, Anjiki H, et al. Pancreaticobiliary maljunction. Clin Gastroenterol Hepatol. 2009;7:S84\u20138.","journal-title":"Clin Gastroenterol Hepatol"},{"key":"1015_CR2","doi-asserted-by":"crossref","first-page":"472","DOI":"10.1007\/s00534-013-0606-2","volume":"20","author":"Y Morine","year":"2013","unstructured":"Morine Y, Shiamda M, Takamatsu H, et al. Clinical features of pancreaticobiliary maljunction: update analysis of 2nd Japan-nationwide survey. J Hepatobiliary Pancreat Surg. 2013;20:472\u201380.","journal-title":"J Hepatobiliary Pancreat Surg"},{"key":"1015_CR3","doi-asserted-by":"crossref","first-page":"731","DOI":"10.1007\/s00535-012-0611-2","volume":"47","author":"T Kamisawa","year":"2012","unstructured":"Kamisawa T, Ando H, Suyama M, et al. Japanese clinical practice guidelines for pancreaticobiliary maljunction. J Gastroenterol. 2012;47:731\u201359.","journal-title":"J Gastroenterol"},{"key":"1015_CR4","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1002\/jhbp.57","volume":"21","author":"T Kamisawa","year":"2014","unstructured":"Kamisawa T, Ando H, Hamada Y, et al. Diagnostic criteria for pancreaticobiliary maljunction 2013. J Hepatobiliary Pancreat Sci. 2014;21:159\u201361.","journal-title":"J Hepatobiliary Pancreat Sci"},{"key":"1015_CR5","first-page":"115","volume":"8","author":"The Japanese Study Group on Pancreaticobiliary Maljunction (JSGPM)","year":"1987","unstructured":"The Japanese Study Group on Pancreaticobiliary Maljunction (JSGPM), Committee for Diagnostic Criteria for Pancreaticobiliary Maljunction. Diagnostic criteria of pancreaticobiliary maljunction (in Japanese). Tan to Sui. 1987;8:115\u20138.","journal-title":"Tan to Sui"},{"key":"1015_CR6","first-page":"219","volume":"1","author":"The Japanese Study Group on Pancreaticobiliary Maljunction (JSPBM)","year":"1994","unstructured":"The Japanese Study Group on Pancreaticobiliary Maljunction (JSPBM), The Committee of JSPBM for Diagnostic Criteria. Diagnostic criteria of pancreaticobiliary maljunction. J HeptobiliaryPancreat Surg. 1994;1:219\u201321.","journal-title":"J HeptobiliaryPancreat Surg"},{"key":"1015_CR7","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1148\/radiology.203.2.9114096","volume":"203","author":"S Hirohashi","year":"1997","unstructured":"Hirohashi S, Hirohashi R, Uchida H, et al. Pancreatitis: evaluation with MR cholangiopancreatography in children. Radiology. 1997;203:411\u20135.","journal-title":"Radiology"},{"key":"1015_CR8","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1016\/S0039-6060(98)70159-X","volume":"123","author":"M Sugiyama","year":"1998","unstructured":"Sugiyama M, Baba M, Atomi Y, et al. Diagnosis of anomalous pancreaticobiliary junction: value of magnetic resonance cholangiopancreatography. Surgery. 1998;123:391\u20137.","journal-title":"Surgery"},{"key":"1015_CR9","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1148\/radiology.209.2.9807571","volume":"209","author":"C Matos","year":"1998","unstructured":"Matos C, Nicaise N, Deviere J, et al. Choledochal cysts: comparison of findings at MR cholangiopancreatography and endoscopic retrograde cholangiopancreatography in eight patients. Radiology. 1998;209:443\u20138.","journal-title":"Radiology"},{"key":"1015_CR10","doi-asserted-by":"crossref","first-page":"209","DOI":"10.2214\/ajr.179.1.1790209","volume":"179","author":"MJ Kim","year":"2002","unstructured":"Kim MJ, Han SJ, Yoon CS, et al. Using MR cholangiopancreatography to reveal anomalous pancreaticobiliary ductal union in infants and children with choledochal cysts. Am J Roentgenol. 2002;179:209\u201314.","journal-title":"Am J Roentgenol"},{"key":"1015_CR11","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1007\/s00261-006-9005-3","volume":"32","author":"T Kamisawa","year":"2007","unstructured":"Kamisawa T, Tu Y, Egawa N, et al. MRCP of congenital pancreaticobiliary malformation. Abdom Imaging. 2007;32:129\u201333.","journal-title":"Abdom Imaging"},{"key":"1015_CR12","doi-asserted-by":"crossref","unstructured":"Itokawa F, Kamisawa T, Nakano T, et al. Exploring the length of the common channel of pancreaticobiliary maljunction on magnetic resonance cholangiopancreatography. J HepatobiliaryPancreat Sci. doi: 10.1002\/jhbp.168 (Epub ahead of print)","DOI":"10.1002\/jhbp.168"},{"key":"1015_CR13","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1016\/S0016-5107(97)70268-2","volume":"45","author":"M Sugiyama","year":"1997","unstructured":"Sugiyama M, Atomi Y. Endoscopic ultrasonography for diagnosing anomalous pancreaticobiliary junction. Gastrointest Endosc. 1997;45:261\u20137.","journal-title":"Gastrointest Endosc"},{"key":"1015_CR14","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1111\/j.1440-1746.2003.03142.x","volume":"19","author":"TE Yusuf","year":"2004","unstructured":"Yusuf TE, Bhutani MS. Role of endoscopic ultrasonography in diseases of the extrahepatic biliary system. J Gastroenterol Hepatol. 2004;19:243\u201350.","journal-title":"J Gastroenterol Hepatol"},{"key":"1015_CR15","first-page":"119","volume":"21","author":"M Matsuda","year":"2007","unstructured":"Matsuda M, Watanabe G, Hashimoto M, et al. Evaluation of pancreaticobiliary maljunction and low bile amylase levels (in Japanese with English abstract). J Jpn Biliary Assoc. 2007;21:119\u201324.","journal-title":"J Jpn Biliary Assoc"},{"key":"1015_CR16","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1055\/s-2008-1066189","volume":"5","author":"T Todani","year":"1995","unstructured":"Todani T, Urushihara N, Morotomi Y, et al. Characteristics of choledochal cysts in neonates and early infants. Eur J Pediatr Surg. 1995;5:143\u20135.","journal-title":"Eur J Pediatr Surg"},{"key":"1015_CR17","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1159\/000055902","volume":"2","author":"T Kamisawa","year":"2002","unstructured":"Kamisawa T, Amemiya K, Tu Y, et al. Clinical significance of a long common channel. Pancreatology. 2002;2:122\u20138.","journal-title":"Pancreatology"},{"key":"1015_CR18","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1016\/S0016-5107(04)01290-8","volume":"60","author":"T Kamisawa","year":"2004","unstructured":"Kamisawa T, Funata N, Hayashi Y, et al. Pathologic changes in the non-carcinomatous epithelium of the gallbladder in patients with a relatively long common channel. Gastrointest Endosc. 2004;60:56\u201360.","journal-title":"Gastrointest Endosc"},{"key":"1015_CR19","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1111\/j.0915-5635.2006.00603.x","volume":"18","author":"T Kamisawa","year":"2006","unstructured":"Kamisawa T, Go K, Chen PY, et al. Lesions with a high risk of carcinogenesis in the gallbladder of patients with a long common channel. Dig Endosc. 2006;18:192\u20135.","journal-title":"Dig Endosc"},{"key":"1015_CR20","first-page":"1269","volume":"31","author":"Y Hamada","year":"2010","unstructured":"Hamada Y, Takehara H, Ando H, et al. Definition of biliary dilatation based on standard diameter of the bile duct in children (in Japanese). Tan to Sui. 2010;31:1269\u201372.","journal-title":"Tan to Sui"},{"key":"1015_CR21","doi-asserted-by":"crossref","first-page":"1045","DOI":"10.1007\/s00535-012-0702-0","volume":"48","author":"T Itoi","year":"2013","unstructured":"Itoi T, Kamisawa T, Fujii H, et al. Extrahepatic bile duct measurement by using transabdominal ultrasound in Japanese adults: multi-center prospective study. J Gastroenterol. 2013;48:1045\u201350.","journal-title":"J Gastroenterol"},{"key":"1015_CR22","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1002\/jhbp.8","volume":"21","author":"T Kamisawa","year":"2014","unstructured":"Kamisawa T, Ando H, Shimada M, et al. Recent advances and problems in the management of pancreaticobiliary maljunction: feedback from the guidelines committee. J Hepatobiliary Pancreat Sci. 2014;21:87\u201392.","journal-title":"J Hepatobiliary Pancreat Sci"},{"key":"1015_CR23","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1007\/s00423-008-0336-0","volume":"394","author":"T Funabiki","year":"2009","unstructured":"Funabiki T, Matsubara T, Miyakawa S, et al. Pancreaticobiliary maljunction and carcinogenesis to biliary and pancreatic malignancy. Langenbecks Arch Surg. 2009;394:159\u201369.","journal-title":"Langenbecks Arch Surg"},{"key":"1015_CR24","doi-asserted-by":"crossref","first-page":"570","DOI":"10.1016\/S1499-3872(11)60098-2","volume":"10","author":"YL Deng","year":"2011","unstructured":"Deng YL, Cheng NS, Lin YX, et al. Relationship between pancreaticobiliary maljunction and gallbladder carcinoma: a meta-analysis. Hepatobiliary Pancreat Dis Int. 2011;10:570\u201380.","journal-title":"Hepatobiliary Pancreat Dis Int"},{"key":"1015_CR25","doi-asserted-by":"crossref","unstructured":"Li Y, Wei J, Zhao Z, et al. Pancreaticobiliary maljunction is associated with common bile duct carcinoma: a meta-analysis. Sci World J. 2013;618670. doi: 10.1155\/2013\/618670","DOI":"10.1155\/2013\/618670"},{"key":"1015_CR26","doi-asserted-by":"crossref","first-page":"850","DOI":"10.1093\/jjco\/hyp106","volume":"39","author":"T Matsuda","year":"2009","unstructured":"Matsuda T, Marugame T, Kamo K, et al. Cancer incidence and incidence rates in Japan in 2003: based on data from 13 population-based cancer registries in the monitoring of cancer incidence in Japan (MCIJ) project. Jpn J Clin Oncol. 2009;39:850\u20138.","journal-title":"Jpn J Clin Oncol"},{"key":"1015_CR27","doi-asserted-by":"crossref","first-page":"374","DOI":"10.1007\/s005340170011","volume":"8","author":"A Ogawa","year":"2001","unstructured":"Ogawa A, Sugo H, Takamori S, et al. Double cancers in the common bile duct: molecular genetic findings with an analysis of LOH. J Hepatobiliary Pancreat Surg. 2001;8:374\u20138.","journal-title":"J Hepatobiliary Pancreat Surg"},{"key":"1015_CR28","doi-asserted-by":"crossref","first-page":"394","DOI":"10.1016\/S1072-7515(02)01664-2","volume":"196","author":"A Okamoto","year":"2003","unstructured":"Okamoto A, Tsuruta K, Matsumoto G, et al. Papillary carcinoma of the extrahepatic bile duct: characteristic features and implications in surgical treatment. J Am Coll Surg. 2003;196:394\u2013401.","journal-title":"J Am Coll Surg"},{"key":"1015_CR29","doi-asserted-by":"crossref","first-page":"638","DOI":"10.1093\/jjco\/hyl077","volume":"36","author":"H Hori","year":"2006","unstructured":"Hori H, Ajiki T, Fujita T, et al. Double cancer of gall bladder and bile duct not associated with anomalous junction of the pancreaticobiliary duct system. Jpn J Clin Oncol. 2006;36:638\u201342.","journal-title":"Jpn J Clin Oncol"},{"key":"1015_CR30","doi-asserted-by":"crossref","first-page":"338","DOI":"10.1007\/s00534-007-1245-2","volume":"15","author":"T Itoh","year":"2008","unstructured":"Itoh T, Fuji N, Taniguchi H, et al. Double cancer of the cystic duct and gallbladder associated with low junction of the cystic duct. J Hepatobiliary Pancreat Surg. 2008;15:338\u201343.","journal-title":"J Hepatobiliary Pancreat Surg"},{"key":"1015_CR31","first-page":"280","volume":"11","author":"T Fujii","year":"2004","unstructured":"Fujii T, Kaneko T, Sugimoto H, et al. Metachronous double cancer of the gallbladder and common bile duct. J Hepatobiliary Pancreat Surg. 2004;11:280\u20135.","journal-title":"J Hepatobiliary Pancreat Surg"},{"key":"1015_CR32","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1007\/s00534-007-1276-8","volume":"15","author":"M Miyazaki","year":"2008","unstructured":"Miyazaki M, Takada T, Miyakawa S, et al. Risk factors for biliary tract and ampullary carcinomas and prophylactic surgery for these factors. J Hepatobiliary Pancreat Surg. 2008;15:15\u201324.","journal-title":"J Hepatobiliary Pancreat Surg"},{"key":"1015_CR33","doi-asserted-by":"crossref","first-page":"438","DOI":"10.1002\/hep.1840130310","volume":"13","author":"K Shimada","year":"1991","unstructured":"Shimada K, Yanagisawa J, Nakayama F. Increased lysophosphatidylcholine and pancreatic enzyme content in bile of patients with anomalous pancreaticobiliary ductal junction. Hepatology. 1991;13:438\u201344.","journal-title":"Hepatology"},{"key":"1015_CR34","doi-asserted-by":"crossref","first-page":"130","DOI":"10.4251\/wjgo.v2.i3.130","volume":"2","author":"A Tsuchida","year":"2010","unstructured":"Tsuchida A, Itoi T. Carcinogenesis and chemoprevention of biliary tract cancer in pancreaticobiliary maljunction. World J Gastrointest Oncol. 2010;2:130\u20135.","journal-title":"World J Gastrointest Oncol"},{"key":"1015_CR35","doi-asserted-by":"crossref","first-page":"2226","DOI":"10.1002\/1097-0142(19821115)50:10<2226::AID-CNCR2820501043>3.0.CO;2-3","volume":"50","author":"S Kozuka","year":"1982","unstructured":"Kozuka S, Tsubone N, Yasui A, et al. Relation of adenoma to carcinoma in the gallbladder. Cancer. 1982;50:2226\u201334.","journal-title":"Cancer"},{"key":"1015_CR36","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1023\/A:1008330012536","volume":"10","author":"H Watanabe","year":"1999","unstructured":"Watanabe H, Date K, Itoi T, et al. Histological and genetic changes in malignant transformation of gallbladder adenoma. Ann Oncol. 1999;10:136\u20139.","journal-title":"Ann Oncol"},{"key":"1015_CR37","first-page":"295","volume-title":"Pancreaticobiliary maljunction","author":"T Aoki","year":"2002","unstructured":"Aoki T, Tsuchida A, Kasuya K, et al. Carcinogenesis in pancreaticobiliary maljunction. In: Koyanagi Y, Aoki T, editors. Pancreaticobiliary maljunction. Tokyo: Igaku Tosho; 2002. p. 295\u2013302."},{"key":"1015_CR38","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1007\/s00534-002-0741-7","volume":"10","author":"S Tashiro","year":"2003","unstructured":"Tashiro S, Imaizumi T, Ohkawa H, et al. Pancreaticobiliary maljunction: retrospective and nationwide survey in Japan. J Hepatobiliary Pancreat Surg. 2003;10:345\u201351.","journal-title":"J Hepatobiliary Pancreat Surg"},{"key":"1015_CR39","doi-asserted-by":"crossref","first-page":"911","DOI":"10.1046\/j.1365-2168.1998.00744.x","volume":"85","author":"M Sugiyama","year":"1998","unstructured":"Sugiyama M, Atomi Y. Anomalous pancreaticobiliary junction without congenital choledochal cyst. Br J Surg. 1998;85:911\u20136.","journal-title":"Br J Surg"},{"key":"1015_CR40","doi-asserted-by":"crossref","first-page":"312","DOI":"10.1007\/s005340200035","volume":"9","author":"T Matsubara","year":"2002","unstructured":"Matsubara T, Sakurai Y, Zhi L, et al. K-ras and p53 gene mutations in noncancerous biliary lesions of patients with pancreaticobiliary maljunction. J Hepatobiliary Pancreat Surg. 2002;9:312\u201321.","journal-title":"J Hepatobiliary Pancreat Surg"},{"key":"1015_CR41","first-page":"269","volume":"11","author":"A Tsuchida","year":"2004","unstructured":"Tsuchida A, Itoi T, Endo M, et al. Pathological features and surgical outcome of pancreaticobiliary maljunction without dilatation of the extrahepatic bile duct. Oncol Rep. 2004;11:269\u201376.","journal-title":"Oncol Rep"},{"key":"1015_CR42","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1002\/(SICI)1097-0142(19980715)83:2<267::AID-CNCR10>3.0.CO;2-R","volume":"83","author":"S Tanno","year":"1998","unstructured":"Tanno S, Obara T, Fujii T, et al. Proliferative potential and K-ras mutation in epithelial hyperplasia of the gallbladder in patients with anomalous pancreaticobiliary ductal union. Cancer. 1998;83:267\u201375.","journal-title":"Cancer"},{"key":"1015_CR43","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1016\/S0344-0338(11)80778-8","volume":"187","author":"M Yamamoto","year":"1991","unstructured":"Yamamoto M, Nakajo S, Tahara E, et al. Mucosal changes of the gallbladder in anomalous union with the pancreatico-biliary duct system. Pathol Res Pract. 1991;187:241\u20136.","journal-title":"Pathol Res Pract"},{"key":"1015_CR44","doi-asserted-by":"crossref","first-page":"3409","DOI":"10.3748\/wjg.v18.i26.3409","volume":"18","author":"K Takuma","year":"2012","unstructured":"Takuma K, Kamisawa T, Tabata T, et al. Importance of early diagnosis of pancreaticobiliary maljunction without biliary dilatation. World J Gastroenterol. 2012;18:3409\u201314.","journal-title":"World J Gastroenterol"},{"key":"1015_CR45","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1001\/archsurg.1962.01300200077006","volume":"84","author":"GS Dowdy","year":"1962","unstructured":"Dowdy GS, Waldron GW, Brown WG. Surgical anatomy of the pancreatobiliary ductal system. Arch Surg. 1962;84:229\u201346.","journal-title":"Arch Surg"}],"container-title":["Journal of Gastroenterology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00535-014-1015-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00535-014-1015-2\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00535-014-1015-2","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,28]],"date-time":"2019-05-28T22:38:13Z","timestamp":1559083093000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00535-014-1015-2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,11,18]]},"references-count":45,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2015,3]]}},"alternative-id":["1015"],"URL":"https:\/\/doi.org\/10.1007\/s00535-014-1015-2","relation":{},"ISSN":["0944-1174","1435-5922"],"issn-type":[{"value":"0944-1174","type":"print"},{"value":"1435-5922","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,11,18]]}}}