{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,19]],"date-time":"2026-10-19T14:36:36Z","timestamp":1792420596145,"version":"4.5.0"},"reference-count":24,"publisher":"Springer Science and Business Media LLC","issue":"11","license":[{"start":{"date-parts":[[2018,5,2]],"date-time":"2018-05-02T00:00:00Z","timestamp":1525219200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Gastroenterol"],"published-print":{"date-parts":[[2018,11]]},"DOI":"10.1007\/s00535-018-1469-8","type":"journal-article","created":{"date-parts":[[2018,5,2]],"date-time":"2018-05-02T01:07:11Z","timestamp":1525223231000},"page":"1206-1215","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":34,"title":["Impact of tumor localization on the outcomes of surgery for an intrahepatic cholangiocarcinoma"],"prefix":"10.1007","volume":"53","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4398-0697","authenticated-orcid":false,"given":"Tatsuya","family":"Orimo","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Toshiya","family":"Kamiyama","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tomoko","family":"Mitsuhashi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hirofumi","family":"Kamachi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hideki","family":"Yokoo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kenji","family":"Wakayama","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shingo","family":"Shimada","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akihisa","family":"Nagatsu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akinobu","family":"Taketomi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2018,5,2]]},"reference":[{"key":"1469_CR1","doi-asserted-by":"publisher","first-page":"1268","DOI":"10.1016\/j.jhep.2014.01.021","volume":"60","author":"J Bridgewater","year":"2014","unstructured":"Bridgewater J, Galle PR, Khan SA, et al. Guidelines for the diagnosis and management of intrahepatic cholangiocarcinoma. J Hepatol. 2014;60:1268\u201389.","journal-title":"J Hepatol"},{"key":"1469_CR2","doi-asserted-by":"publisher","first-page":"1215","DOI":"10.1053\/j.gastro.2013.10.013","volume":"145","author":"S Rizvi","year":"2013","unstructured":"Rizvi S, Gores GJ. Pathogenesis, diagnosis, and management of cholangiocarcinoma. Gastroenterology. 2013;145:1215\u201329.","journal-title":"Gastroenterology"},{"key":"1469_CR3","doi-asserted-by":"publisher","first-page":"94","DOI":"10.1002\/jhbp.154","volume":"22","author":"S Aishima","year":"2015","unstructured":"Aishima S, Oda Y. Pathogenesis and classification of intrahepatic cholangiocarcinoma: different characters of perihilar large duct type versus peripheral small duct type. J Hepatobiliary Pancreat Sci. 2015;22:94\u2013100.","journal-title":"J Hepatobiliary Pancreat Sci"},{"key":"1469_CR4","doi-asserted-by":"publisher","first-page":"1059","DOI":"10.1097\/PAS.0b013e31802b34b6","volume":"31","author":"S Aishima","year":"2007","unstructured":"Aishima S, Kuroda Y, Nishihara Y, et al. Proposal of progression model for intrahepatic cholangiocarcinoma: clinicopathologic differences between hilar type and peripheral type. Am J Surg Pathol. 2007;31:1059\u201367.","journal-title":"Am J Surg Pathol"},{"key":"1469_CR5","doi-asserted-by":"publisher","first-page":"612","DOI":"10.1111\/j.1477-2574.2011.00340.x","volume":"13","author":"CJ Clark","year":"2011","unstructured":"Clark CJ, Wood-Wentz CM, Reid-Lombardo KM, et al. Lymphadenectomy in the staging and treatment of intrahepatic cholangiocarcinoma: a population-based study using the National Cancer Institute SEER database. HPB (Oxf). 2011;13:612\u201320.","journal-title":"HPB (Oxf)"},{"key":"1469_CR6","doi-asserted-by":"publisher","first-page":"463","DOI":"10.1097\/00000658-199610000-00005","volume":"224","author":"A Nakeeb","year":"1996","unstructured":"Nakeeb A, Pitt HA, Sohn TA, et al. Cholangiocarcinoma. A spectrum of intrahepatic, perihilar, and distal tumors. Ann Surg. 1996;224:463\u201373.","journal-title":"Ann Surg"},{"key":"1469_CR7","doi-asserted-by":"publisher","first-page":"79","DOI":"10.1002\/bjs.9379","volume":"101","author":"T Ebata","year":"2014","unstructured":"Ebata T, Kosuge T, Hirano S, et al. Proposal to modify the International Union Against Cancer staging system for perihilar cholangiocarcinomas. Br J Surg. 2014;101:79\u201388.","journal-title":"Br J Surg"},{"key":"1469_CR8","doi-asserted-by":"publisher","first-page":"540","DOI":"10.1007\/s11605-011-1730-4","volume":"16","author":"Y Murakami","year":"2012","unstructured":"Murakami Y, Uemura K, Sudo T, et al. Intrahepatic cholangiocarcinoma: clinicopathological differences between peripheral type and hilar type. J Gastrointest Surg. 2012;16:540\u20138.","journal-title":"J Gastrointest Surg"},{"key":"1469_CR9","doi-asserted-by":"publisher","first-page":"6563","DOI":"10.21873\/anticanres.11260","volume":"36","author":"YI Yamashita","year":"2016","unstructured":"Yamashita YI, Wang H, Kurihara T, et al. Clinical significances of preoperative classification of intrahepatic cholangiocarcinoma: different characteristics of perihilar vs. peripheral ICC. Anticancer Res. 2016;36:6563\u20139.","journal-title":"Anticancer Res"},{"key":"1469_CR10","doi-asserted-by":"publisher","first-page":"590","DOI":"10.1245\/s10434-007-9687-y","volume":"15","author":"T Sano","year":"2008","unstructured":"Sano T, Shimada K, Sakamoto Y, et al. Prognosis of perihilar cholangiocarcinoma: hilar bile duct cancer versus intrahepatic cholangiocarcinoma involving the hepatic hilus. Ann Surg Oncol. 2008;15:590\u20139.","journal-title":"Ann Surg Oncol"},{"key":"1469_CR11","doi-asserted-by":"publisher","first-page":"443","DOI":"10.1016\/j.jamcollsurg.2010.06.005","volume":"211","author":"T Kamiyama","year":"2010","unstructured":"Kamiyama T, Nakanishi K, Yokoo H, et al. Perioperative management of hepatic resection toward zero mortality and morbidity: analysis of 793 consecutive cases in a single institution. J Am Coll Surg. 2010;211:443\u20139.","journal-title":"J Am Coll Surg"},{"key":"1469_CR12","doi-asserted-by":"publisher","first-page":"69","DOI":"10.1016\/j.jhep.2012.02.022","volume":"57","author":"WC Palmer","year":"2012","unstructured":"Palmer WC, Patel T. Are common factors involved in the pathogenesis of primary liver cancers? A meta-analysis of risk factors for intrahepatic cholangiocarcinoma. J Hepatol. 2012;57:69\u201376.","journal-title":"J Hepatol"},{"issue":"6","key":"1469_CR13","doi-asserted-by":"publisher","first-page":"6120","DOI":"10.1038\/ncomms7120","volume":"30","author":"A Fujimoto","year":"2015","unstructured":"Fujimoto A, Furuta M, Shiraishi Y, et al. Whole-genome mutational landscape of liver cancers displaying biliary phenotype reveals hepatitis impact and molecular diversity. Nat Commun. 2015;30(6):6120.","journal-title":"Nat Commun"},{"key":"1469_CR14","doi-asserted-by":"publisher","first-page":"1082","DOI":"10.1007\/s00268-016-3843-0","volume":"41","author":"H Iida","year":"2017","unstructured":"Iida H, Kaibori M, Tanaka S, et al. Low incidence of lymph node metastasis after resection of hepatitis virus-related intrahepatic cholangiocarcinoma. World J Surg. 2017;41:1082\u20138.","journal-title":"World J Surg"},{"key":"1469_CR15","doi-asserted-by":"publisher","first-page":"565","DOI":"10.1001\/jamasurg.2013.5137","volume":"149","author":"MN Mavros","year":"2014","unstructured":"Mavros MN, Economopoulos KP, Alexiou VG, et al. Treatment and prognosis for patients with intrahepatic cholangiocarcinoma: systematic review and meta-analysis. JAMA Surg. 2014;149:565\u201374.","journal-title":"JAMA Surg"},{"key":"1469_CR16","doi-asserted-by":"publisher","first-page":"e170117","DOI":"10.1001\/jamasurg.2017.0117","volume":"152","author":"M Raoof","year":"2017","unstructured":"Raoof M, Dumitra S, Ituarte PHG, et al. Development and validation of a prognostic score for intrahepatic cholangiocarcinoma. JAMA Surg. 2017;152:e170117.","journal-title":"JAMA Surg"},{"key":"1469_CR17","doi-asserted-by":"publisher","first-page":"1188","DOI":"10.1200\/JCO.2012.41.5984","volume":"31","author":"Y Wang","year":"2013","unstructured":"Wang Y, Li J, Xia Y, et al. Prognostic nomogram for intrahepatic cholangiocarcinoma after partial hepatectomy. J Clin Oncol. 2013;31:1188\u201395.","journal-title":"J Clin Oncol"},{"key":"1469_CR18","doi-asserted-by":"publisher","first-page":"728","DOI":"10.1007\/s00268-005-7761-9","volume":"29","author":"T Nakagawa","year":"2005","unstructured":"Nakagawa T, Kamiyama T, Kurauchi N, et al. Number of lymph node metastases is a significant prognostic factor in intrahepatic cholangiocarcinoma. World J Surg. 2005;29:728\u201333.","journal-title":"World J Surg"},{"key":"1469_CR19","doi-asserted-by":"publisher","first-page":"404","DOI":"10.1245\/s10434-008-0227-1","volume":"16","author":"S Yedibela","year":"2009","unstructured":"Yedibela S, Demir R, Zhang W, et al. Surgical treatment of mass-forming intrahepatic cholangiocarcinoma: an 11-year Western single-center experience in 107 patients. Ann Surg Oncol. 2009;16:404\u201312.","journal-title":"Ann Surg Oncol"},{"key":"1469_CR20","doi-asserted-by":"publisher","first-page":"913","DOI":"10.1007\/s00535-015-1071-2","volume":"50","author":"Y Morine","year":"2015","unstructured":"Morine Y, Shimada M. The value of systematic lymph node dissection for intrahepatic cholangiocarcinoma from the viewpoint of liver lymphatics. J Gastroenterol. 2015;50:913\u201327.","journal-title":"J Gastroenterol"},{"key":"1469_CR21","doi-asserted-by":"publisher","first-page":"3048","DOI":"10.1245\/s10434-009-0631-1","volume":"16","author":"SB Choi","year":"2009","unstructured":"Choi SB, Kim KS, Choi JY, et al. The prognosis and survival outcome of intrahepatic cholangiocarcinoma following surgical resection: association of lymph node metastasis and lymph node dissection with survival. Ann Surg Oncol. 2009;16:3048\u201356.","journal-title":"Ann Surg Oncol"},{"key":"1469_CR22","doi-asserted-by":"publisher","first-page":"666","DOI":"10.1016\/j.surg.2014.11.006","volume":"157","author":"DH Kim","year":"2015","unstructured":"Kim DH, Choi DW, Choi SH, et al. Is there a role for systematic hepatic pedicle lymphadenectomy in intrahepatic cholangiocarcinoma? A review of 17\u00a0years of experience in a tertiary institution. Surgery. 2015;157:666\u201375.","journal-title":"Surgery"},{"key":"1469_CR23","doi-asserted-by":"publisher","first-page":"2269","DOI":"10.1245\/s10434-014-4239-8","volume":"22","author":"T Adachi","year":"2015","unstructured":"Adachi T, Eguchi S, Beppu T, et al. Prognostic impact of preoperative lymph node enlargement in intrahepatic cholangiocarcinoma: a multi-institutional study by the Kyushu Study Group of liver surgery. Ann Surg Oncol. 2015;22:2269\u201378.","journal-title":"Ann Surg Oncol"},{"key":"1469_CR24","doi-asserted-by":"publisher","first-page":"697","DOI":"10.1001\/archsurg.2011.122","volume":"146","author":"MC Jong de","year":"2011","unstructured":"de Jong MC, Hong SM, Augustine MM, et al. Hilar cholangiocarcinoma: tumor depth as a predictor of outcome. Arch Surg. 2011;146:697\u2013703.","journal-title":"Arch Surg"}],"container-title":["Journal of Gastroenterology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00535-018-1469-8\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00535-018-1469-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00535-018-1469-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,1]],"date-time":"2019-05-01T20:03:38Z","timestamp":1556741018000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00535-018-1469-8"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,5,2]]},"references-count":24,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2018,11]]}},"alternative-id":["1469"],"URL":"https:\/\/doi.org\/10.1007\/s00535-018-1469-8","relation":{},"ISSN":["0944-1174","1435-5922"],"issn-type":[{"value":"0944-1174","type":"print"},{"value":"1435-5922","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,5,2]]},"assertion":[{"value":"29 January 2018","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"23 April 2018","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"2 May 2018","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"The authors declare that they have no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}