{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,24]],"date-time":"2026-03-24T11:14:17Z","timestamp":1774350857619,"version":"3.50.1"},"reference-count":25,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2010,1,7]],"date-time":"2010-01-07T00:00:00Z","timestamp":1262822400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Anesth"],"published-print":{"date-parts":[[2010,2]]},"DOI":"10.1007\/s00540-009-0835-3","type":"journal-article","created":{"date-parts":[[2010,1,6]],"date-time":"2010-01-06T07:58:34Z","timestamp":1262764714000},"page":"134-138","source":"Crossref","is-referenced-by-count":15,"title":["Successful use of spinal anesthesia in a patient with severe Klippel\u2013Tr\u00e9naunay syndrome associated with upper airway abnormalities and chronic Kasabach\u2013Merritt coagulopathy"],"prefix":"10.1007","volume":"24","author":[{"given":"Elena J.","family":"Holak","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paul S.","family":"Pagel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2010,1,7]]},"reference":[{"key":"835_CR1","first-page":"611","volume":"3","author":"M Klippel","year":"1900","unstructured":"Klippel M, Trenaunay P. Du noevus variqueux osteo-hypertrophique. Arch Gen Med Paris. 1900;3:611\u201372.","journal-title":"Arch Gen Med Paris"},{"key":"835_CR2","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1002\/bjs.1800720331","volume":"72","author":"PA Baskerville","year":"1985","unstructured":"Baskerville PA, Ackroyd JS, Lea Thomas M, Browse NL. The Klippel\u2013Trenaunay syndrome: clinical, radiological and haemodynamic features and management. Br J Surg. 1985;72:232\u20136.","journal-title":"Br J Surg"},{"key":"835_CR3","doi-asserted-by":"crossref","first-page":"757","DOI":"10.1002\/bjs.1800820615","volume":"82","author":"M Samuel","year":"1995","unstructured":"Samuel M, Spitz L. Klippel\u2013Trenaunay syndrome: clinical features, complications and management in children. Br J Surg. 1995;82:757\u201361.","journal-title":"Br J Surg"},{"key":"835_CR4","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1016\/j.jaad.2003.12.017","volume":"51","author":"C Maari","year":"2004","unstructured":"Maari C, Frieden IJ. Klippel\u2013Trenaunay syndrome: the importance of \u201cgeographic stains\u201d in identifying lymphatic disease and risk of complications. J Am Acad Dermatol. 2004;51:391\u20138.","journal-title":"J Am Acad Dermatol"},{"key":"835_CR5","doi-asserted-by":"crossref","first-page":"744","DOI":"10.1542\/peds.2004-0446","volume":"115","author":"A Lee","year":"2005","unstructured":"Lee A, Driscoll D, Gloviczki P, Clay R, Shaughnessy W, Stans A. Evaluation and management of pain in patients with Klippel\u2013Trenaunay syndrome: a review. Pediatrics. 2005;115:744\u20139.","journal-title":"Pediatrics"},{"key":"835_CR6","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1097\/SAP.0b013e318062abc1","volume":"60","author":"CE Oduber","year":"2008","unstructured":"Oduber CE, van der Horst CM. Hennekam RC Klippel\u2013Trenaunay syndrome Diagnostic criteria and hypothesis on etiology. Ann Plast Surg. 2008;60:217\u201323.","journal-title":"Ann Plast Surg"},{"key":"835_CR7","first-page":"231","volume":"19","author":"F Parkes-Weber","year":"1907","unstructured":"Parkes-Weber F. Angioma-formation in connection with hypertrophy of limbs and hemi-hypertrophy. Br J Dermatol. 1907;19:231\u20135.","journal-title":"Br J Dermatol"},{"key":"835_CR8","first-page":"2783","volume":"96","author":"CL Wilson","year":"2001","unstructured":"Wilson CL, Song LM, Chua H, Ferrara M, Devine RM, Dozois RR, et al. Bleeding from cavernous angiomatosis of the rectum in Klippel\u2013Trenaunay syndrome: report of three cases and literature review. Am J Gastroenterol. 2001;96:2783\u20138.","journal-title":"Am J Gastroenterol"},{"key":"835_CR9","doi-asserted-by":"crossref","first-page":"1244","DOI":"10.1016\/j.juro.2006.11.099","volume":"177","author":"DA Husmann","year":"2007","unstructured":"Husmann DA, Rathburn SR, Driscoll DJ. Klippel\u2013Trenaunay syndrome: incidence and treatment of genitourinary sequelae. J Urol. 2007;177:1244\u20139.","journal-title":"J Urol"},{"key":"835_CR10","doi-asserted-by":"crossref","first-page":"814","DOI":"10.3171\/jns.1978.48.5.0814","volume":"48","author":"M Gourie-Devi","year":"1978","unstructured":"Gourie-Devi M, Prakash B. Vertebral and epidural hemangioma with paraplegia in Klippel\u2013Trenaunay\u2013Weber syndrome. Case report. J Neurosurg. 1978;48:814\u20137.","journal-title":"J Neurosurg"},{"key":"835_CR11","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1016\/0952-8180(91)90187-R","volume":"3","author":"OA Leon-Casasola de","year":"1991","unstructured":"de Leon-Casasola OA, Lema MJ. Anesthesia for patients with Sturge\u2013Weber disease and Klippel\u2013Trenaunay syndrome. J Clin Anesth. 1991;3:409\u201313.","journal-title":"J Clin Anesth"},{"key":"835_CR12","doi-asserted-by":"crossref","first-page":"316","DOI":"10.1016\/0952-8180(95)00046-K","volume":"7","author":"RR Gaiser","year":"1995","unstructured":"Gaiser RR, Cheek TG, Gutsche BB. Major conduction anesthesia in a patient with Klippel\u2013Trenaunay syndrome. J Clin Anesth. 1995;7:316\u20139.","journal-title":"J Clin Anesth"},{"key":"835_CR13","first-page":"341","volume":"15","author":"R Hofer","year":"2005","unstructured":"Hofer R, Frank J, Itin PH. Klippel\u2013Trenaunay syndrome in a monozygotic male twin: supportive evidence for the concept of paradominant inheritance. Eur J Dermatol. 2005;15:341\u20133.","journal-title":"Eur J Dermatol"},{"key":"835_CR14","doi-asserted-by":"crossref","first-page":"748","DOI":"10.1038\/nrg906","volume":"3","author":"H Youssoufian","year":"2002","unstructured":"Youssoufian H, Pyeritz RE. Mechanisms and consequences of somatic mosaicism in humans. Nat Rev Genet. 2002;3:748\u201358.","journal-title":"Nat Rev Genet"},{"key":"835_CR15","doi-asserted-by":"crossref","first-page":"1275","DOI":"10.1097\/00006123-200211000-00025","volume":"51","author":"MJ Alexander","year":"2002","unstructured":"Alexander MJ, Grossi PM, Spetzler RF, McDougall CG. Extradural thoracic arteriovenous malformation in a patient with Klippel\u2013Trenaunay\u2013Weber syndrome: case report. Neurosurgery. 2002;51:1275\u20138.","journal-title":"Neurosurgery"},{"key":"835_CR16","first-page":"352","volume":"73","author":"DW Eastwood","year":"1991","unstructured":"Eastwood DW. Hematoma after epidural anesthesia: relationship of skin and spinal angiomas. Anesth Analg. 1991;73:352\u20134.","journal-title":"Anesth Analg"},{"key":"835_CR17","doi-asserted-by":"crossref","first-page":"470","DOI":"10.1213\/00000539-199203000-00030","volume":"74","author":"OA Leon-Casasola de","year":"1992","unstructured":"de Leon-Casasola OA, Lema MJ. Epidural anesthesia in patients with Klippel\u2013Trenaunay syndrome. Anesth Analg. 1992;74:470\u20131.","journal-title":"Anesth Analg"},{"key":"835_CR18","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1007\/BF03022622","volume":"53","author":"MJ Sivaprakasam","year":"2006","unstructured":"Sivaprakasam MJ, Dolak JA. Anesthetic and obstetric considerations in a parturient with Klippel\u2013Trenaunay syndrome. Can J Anaesth. 2006;53:487\u201391.","journal-title":"Can J Anaesth"},{"key":"835_CR19","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1093\/bja\/82.1.144","volume":"82","author":"P Dobbs","year":"1999","unstructured":"Dobbs P, Caunt A, Alderson TJ. Epidural analgesia in an obstetric patient with Klippel\u2013Trenaunay syndrome. Br J Anaesth. 1999;82:144\u20136.","journal-title":"Br J Anaesth"},{"key":"835_CR20","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1177\/0310057X9802600318","volume":"26","author":"IW Christie","year":"1998","unstructured":"Christie IW, Ahkine PA, Holland RL. Central regional anaesthesia in a patient with Klippel\u2013Trenaunay syndrome. Anaesth Intensive Care. 1998;26:319\u201321.","journal-title":"Anaesth Intensive Care"},{"key":"835_CR21","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/S0022-3468(88)80135-0","volume":"23","author":"M el-Dessouky","year":"1988","unstructured":"el-Dessouky M, Azmy AF, Raine PA, Young DG. Kasabach\u2013Merritt syndrome. J Pediatr Surg. 1988;23:109\u201311.","journal-title":"J Pediatr Surg"},{"key":"835_CR22","doi-asserted-by":"crossref","first-page":"851","DOI":"10.1046\/j.1365-2141.2001.02453.x","volume":"112","author":"GW Hall","year":"2001","unstructured":"Hall GW. Kasabach\u2013Merritt syndrome: pathogenesis and management. Br J Haematol. 2001;112:851\u201362.","journal-title":"Br J Haematol"},{"key":"835_CR23","doi-asserted-by":"crossref","first-page":"1073","DOI":"10.1097\/00007611-199811000-00019","volume":"91","author":"DM Aronoff","year":"1998","unstructured":"Aronoff DM, Roshon M. Severe hemorrhage complicating the Klippel\u2013Trenaunay\u2013Weber syndrome. South Med J. 1998;91:1073\u20135.","journal-title":"South Med J"},{"key":"835_CR24","doi-asserted-by":"crossref","first-page":"746","DOI":"10.1016\/S0022-3476(05)83334-7","volume":"117","author":"BL Shulkin","year":"1990","unstructured":"Shulkin BL, Argenta LC, Cho KJ, Castle VP. Kasabach\u2013Merritt syndrome: treatment with epsilon-aminocaproic acid and assessment by indium 111 platelet scintigraphy. J Pediatr. 1990;117:746\u20139.","journal-title":"J Pediatr"},{"key":"835_CR25","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1111\/j.1460-9592.2008.02749.x","volume":"19","author":"D Janic","year":"2009","unstructured":"Janic D, Brasanac D, Krstovski N, Dokmanovic L, Lazic J, Krstic Z. The use of recombinant activated factor VII during major surgery in a child with Kasabach\u2013Merritt syndrome. Paediatr Anaesth. 2009;19:177\u20139.","journal-title":"Paediatr Anaesth"}],"container-title":["Journal of Anesthesia"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00540-009-0835-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00540-009-0835-3\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00540-009-0835-3","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,29]],"date-time":"2019-05-29T02:43:55Z","timestamp":1559097835000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00540-009-0835-3"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,1,7]]},"references-count":25,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2010,2]]}},"alternative-id":["835"],"URL":"https:\/\/doi.org\/10.1007\/s00540-009-0835-3","relation":{},"ISSN":["0913-8668","1438-8359"],"issn-type":[{"value":"0913-8668","type":"print"},{"value":"1438-8359","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,1,7]]}}}