{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,2]],"date-time":"2026-02-02T07:48:33Z","timestamp":1770018513058,"version":"3.49.0"},"reference-count":28,"publisher":"Springer Science and Business Media LLC","issue":"5","license":[{"start":{"date-parts":[[2019,8,17]],"date-time":"2019-08-17T00:00:00Z","timestamp":1566000000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2019,8,17]],"date-time":"2019-08-17T00:00:00Z","timestamp":1566000000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Anesth"],"published-print":{"date-parts":[[2019,10]]},"DOI":"10.1007\/s00540-019-02672-y","type":"journal-article","created":{"date-parts":[[2019,8,17]],"date-time":"2019-08-17T03:02:37Z","timestamp":1566010957000},"page":"594-599","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Resting pupil size is a predictor of hypotension after induction of general anesthesia"],"prefix":"10.1007","volume":"33","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4043-049X","authenticated-orcid":false,"given":"Ryohei","family":"Miyazaki","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Makoto","family":"Sumie","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tadashi","family":"Kandabashi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ken","family":"Yamaura","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2019,8,17]]},"reference":[{"key":"2672_CR1","doi-asserted-by":"publisher","first-page":"35","DOI":"10.1097\/ALN.0000000000000922","volume":"124","author":"JA van Waes","year":"2016","unstructured":"van Waes JA, van Klei WA, Wijeysundera DN, van Wolfswinkel L, Lindsay TF, Beattie WS. Association between intraoperative hypotension and myocardial injury after vascular surgery. Anesthesiology. 2016;124:35\u201344.","journal-title":"Anesthesiology"},{"key":"2672_CR2","doi-asserted-by":"publisher","first-page":"658","DOI":"10.1097\/ALN.0b013e3182472320","volume":"116","author":"JB Bijker","year":"2012","unstructured":"Bijker JB, Persoon S, Peelen LM, Moons KG, Kalkman CJ, Kappelle LJ, van Klei WA. Intraoperative hypotension and perioperative ischemic stroke after general surgery: a nested case\u2013control study. Anesthesiology. 2012;116:658\u201364.","journal-title":"Anesthesiology"},{"key":"2672_CR3","doi-asserted-by":"publisher","first-page":"1223","DOI":"10.1111\/anae.14416","volume":"73","author":"K Maheshwari","year":"2018","unstructured":"Maheshwari K, Turan A, Mao G, Yang D, Niazi AK, Agarwal D, Sessler DI, Kurz A. The association of hypotension during non-cardiac surgery, before and after skin incision, with postoperative acute kidney injury: a retrospective cohort analysis. Anaesthesia. 2018;73:1223\u20138.","journal-title":"Anaesthesia"},{"key":"2672_CR4","doi-asserted-by":"publisher","first-page":"492","DOI":"10.1007\/s00540-011-1152-1","volume":"25","author":"V Tassoudis","year":"2011","unstructured":"Tassoudis V, Vretzakis G, Petsiti A, Stamatiou G, Bouzia K, Melekos M, Tzovaras G. Impact of intraoperative hypotension on hospital stay in major abdominal surgery. J Anesth. 2011;25:492\u20139.","journal-title":"J Anesth"},{"key":"2672_CR5","doi-asserted-by":"publisher","first-page":"307","DOI":"10.1097\/ALN.0000000000000756","volume":"123","author":"TG Monk","year":"2015","unstructured":"Monk TG, Bronsert MR, Henderson WG, Mangione MP, Sum-Ping ST, Bentt DR, Nguyen JD, Richman JS, Meguid RA, Hammermeister KE. Association between intraoperative hypotension and hypertension and 30-day postoperative mortality in noncardiac surgery. Anesthesiology. 2015;123:307\u201319.","journal-title":"Anesthesiology"},{"key":"2672_CR6","doi-asserted-by":"publisher","first-page":"622","DOI":"10.1213\/01.ANE.0000175214.38450.91","volume":"101","author":"DL Reich","year":"2005","unstructured":"Reich DL, Hossain S, Krol M, Baez B, Patel P, Bernstein A, Bodian CA. Predictors of hypotension after induction of general anesthesia. Anesth Analg. 2005;101:622\u20138.","journal-title":"Anesth Analg"},{"key":"2672_CR7","doi-asserted-by":"publisher","first-page":"57","DOI":"10.1093\/bja\/aex127","volume":"119","author":"S S\u00fcdfeld","year":"2017","unstructured":"S\u00fcdfeld S, Brechnitz S, Wagner JY, Reese PC, Pinnschmidt HO, Reuter DA, Saugel B. Post-induction hypotension and early intraoperative hypotension associated with general anaesthesia. Br J Anaesth. 2017;119:57\u201364.","journal-title":"Br J Anaesth"},{"key":"2672_CR8","doi-asserted-by":"publisher","first-page":"591","DOI":"10.1097\/00000542-198904000-00006","volume":"70","author":"LG Burgos","year":"1989","unstructured":"Burgos LG, Ebert TJ, Asiddao C, Turner LA, Pattison CZ, Wang-Cheng R, Kampine JP. Increased intraoperative cardiovascular morbidity in diabetics with autonomic neuropathy. Anesthesiology. 1989;70:591\u20137.","journal-title":"Anesthesiology"},{"key":"2672_CR9","doi-asserted-by":"publisher","first-page":"1170","DOI":"10.1111\/j.1399-6576.2006.01130.x","volume":"50","author":"B Bein","year":"2006","unstructured":"Bein B, Hanss R, Scholz J, Tonner PH. Pre-operative measurement of heart rate variability and incidence of hypotension. Acta Anaesthesiol Scand. 2006;50:1170\u20131.","journal-title":"Acta Anaesthesiol Scand"},{"key":"2672_CR10","volume-title":"The Pupil: Anatomy, Physiology, and Clinical Applications","author":"IE Loewenfeld","year":"1999","unstructured":"Loewenfeld IE, Lowenstein O. The Pupil: Anatomy, Physiology, and Clinical Applications. Oxford: Butterworth Heinemann; 1999."},{"key":"2672_CR11","doi-asserted-by":"publisher","first-page":"297","DOI":"10.1007\/s10286-013-0209-7","volume":"23","author":"S Muppidi","year":"2013","unstructured":"Muppidi S, Adams-Huet B, Tajzoy E, Scribner M, Blazek P, Spaeth EB, Frohman E, Davis S, Vernino S. Dynamic pupillometry as an autonomic testing tool. Clin Auton Res. 2013;23:297\u2013303.","journal-title":"Clin Auton Res"},{"key":"2672_CR12","doi-asserted-by":"publisher","first-page":"1093","DOI":"10.1097\/OPX.0000000000000893","volume":"93","author":"M Guillon","year":"2016","unstructured":"Guillon M, Dumbleton K, Theodoratos P, Gobbe M, Wooley CB, Moody K. The effects of age, refractive status, and luminance on pupil size. Optom Vis Sci. 2016;93:1093\u2013100.","journal-title":"Optom Vis Sci"},{"key":"2672_CR13","doi-asserted-by":"publisher","first-page":"380","DOI":"10.1111\/j.1755-3768.1971.tb00964.x","volume":"49","author":"A Borthne","year":"1971","unstructured":"Borthne A, Davanger M. Mydriatics and age. Acta Ophthalmol. 1971;49:380\u20137.","journal-title":"Acta Ophthalmol"},{"key":"2672_CR14","first-page":"2099","volume":"20","author":"S Okutucu","year":"2016","unstructured":"Okutucu S, Civelekler M, Aparci M, Sabanoglu C, Dikmetas O, Aksoy H, Yetis Sayin B, Oto A. Computerized dynamic pupillometry indices mirrors the heart rate variability parameters. Eur Rev Med Pharmacol Sci. 2016;20:2099\u2013105.","journal-title":"Eur Rev Med Pharmacol Sci"},{"key":"2672_CR15","first-page":"496","volume":"103","author":"AN Boev","year":"2005","unstructured":"Boev AN, Fountas KN, Karampelas I, Boev C, Machinis TG, Feltes C, Okosun I, Dimopoulos V, Troup C. Quantitative pupillometry: normative data in healthy pediatric volunteers. J Neurosurg. 2005;103:496\u2013500.","journal-title":"J Neurosurg"},{"key":"2672_CR16","doi-asserted-by":"publisher","first-page":"2102","DOI":"10.1007\/s00134-018-5448-6","volume":"44","author":"M Oddo","year":"2018","unstructured":"Oddo M, Sandroni C, Citerio G, Miroz JP, Horn J, Rundgren M, Cariou A, Payen JF, Storm C, Stammet P, Taccone FS. Quantitative versus standard pupillary light reflex for early prognostication in comatose cardiac arrest patients: an international prospective multicenter double-blinded study. Intensive Care Med. 2018;44:2102\u201311.","journal-title":"Intensive Care Med"},{"key":"2672_CR17","doi-asserted-by":"publisher","first-page":"155","DOI":"10.1186\/s13054-019-2436-3","volume":"23","author":"FP Jahns","year":"2019","unstructured":"Jahns FP, Miroz JP, Messerer M, Daniel RT, Taccone FS, Eckert P, Oddo M. Quantitative pupillometry for the monitoring of intracranial hypertension in patients with severe traumatic brain injury. Crit Care. 2019;23:155.","journal-title":"Crit Care"},{"key":"2672_CR18","doi-asserted-by":"publisher","DOI":"10.1097\/ANA.0000000000000553","author":"S Natzeder","year":"2018","unstructured":"Natzeder S, Mack DJ, Maissen G, Str\u00e4ssle C, Keller E, Muroi C. Portable infrared pupillometer in patients with subarachnoid hemorrhage: prognostic value and circadian rhythm of the Neurological Pupil Index (NPi). J Neurosurg Anesthesiol. 2018. https:\/\/doi.org\/10.1097\/ANA.0000000000000553.","journal-title":"J Neurosurg Anesthesiol"},{"key":"2672_CR19","doi-asserted-by":"publisher","first-page":"1037","DOI":"10.1097\/ALN.0000000000000384","volume":"121","author":"MD Rollins","year":"2014","unstructured":"Rollins MD, Feiner JR, Lee JM, Shah S, Larson M. Pupillary effects of high-dose opioid quantified with infrared pupillometry. Anesthesiology. 2014;121:1037\u201344.","journal-title":"Anesthesiology"},{"key":"2672_CR20","doi-asserted-by":"publisher","first-page":"1373","DOI":"10.1016\/S0895-4356(96)00236-3","volume":"49","author":"P Peduzzi","year":"1996","unstructured":"Peduzzi P, Concato J, Kemper E, Holford TR, Feinstein AR. A simulation study of the number of events per variable in logistic regression analysis. J Clin Epidemiol. 1996;49:1373\u20139.","journal-title":"J Clin Epidemiol"},{"key":"2672_CR21","doi-asserted-by":"publisher","first-page":"491","DOI":"10.2337\/diacare.8.5.491","volume":"8","author":"DJ Ewing","year":"1985","unstructured":"Ewing DJ, Martyn CN, Young RJ, Clarke BF. The value of cardiovascular autonomic function tests: 10 years experience in diabetes. Diabetes Care. 1985;8:491\u20138.","journal-title":"Diabetes Care"},{"key":"2672_CR22","doi-asserted-by":"publisher","first-page":"461","DOI":"10.1081\/CBI-120002913","volume":"19","author":"RC Hermida","year":"2002","unstructured":"Hermida RC, Ayala DE, Fern\u00e1ndez JR, Moj\u00f3n A, Alonso I, Calvo C. Modeling the circadian variability of ambulatorily monitored blood pressure by multiple-component analysis. Chronobiol Int. 2002;19:461\u201381.","journal-title":"Chronobiol Int"},{"key":"2672_CR23","doi-asserted-by":"publisher","first-page":"148","DOI":"10.1111\/j.1365-2869.2007.00581.x","volume":"16","author":"G Vandewalle","year":"2007","unstructured":"Vandewalle G, Middleton B, Rajaratnam SM, Stone BM, Thorleifsdottir B, Arendt J, Dijk DJ. Robust circadian rhythm in heart rate and its variability: influence of exogenous melatonin and photoperiod. J Sleep Res. 2007;16:148\u201355.","journal-title":"J Sleep Res"},{"key":"2672_CR24","doi-asserted-by":"publisher","first-page":"49","DOI":"10.1016\/0301-0511(79)90022-X","volume":"9","author":"P Lavie","year":"1979","unstructured":"Lavie P. Ultradian rhythms in alertness\u2014a pupillometric study. Biol Psychol. 1979;9:49\u201362.","journal-title":"Biol Psychol"},{"key":"2672_CR25","doi-asserted-by":"publisher","first-page":"108","DOI":"10.3389\/fneur.2019.00108","volume":"10","author":"I Daguet","year":"2019","unstructured":"Daguet I, Bouhassira D, Gronfier C. Baseline pupil diameter is not a reliable biomarker of subjective sleepiness. Front Neurol. 2019;10:108.","journal-title":"Front Neurol"},{"key":"2672_CR26","volume-title":"Pupillary changes related to age","author":"IE Loewenfeld","year":"1979","unstructured":"Loewenfeld IE. Pupillary changes related to age. Baltimore: Williams and Wilkins; 1979."},{"issue":"Suppl 1","key":"2672_CR27","doi-asserted-by":"publisher","first-page":"S1","DOI":"10.1291\/hypres.19.SupplementI_S1","volume":"19","author":"O Iimura","year":"1996","unstructured":"Iimura O. Insulin resistance and hypertension in Japanese. Hypertens Res. 1996;19(Suppl 1):S1\u20138.","journal-title":"Hypertens Res"},{"key":"2672_CR28","doi-asserted-by":"publisher","first-page":"458","DOI":"10.1161\/01.HYP.0000032853.95690.26","volume":"40","author":"P Henry","year":"2002","unstructured":"Henry P, Thomas F, Benetos A, Guize L. Impaired fasting glucose, blood pressure and cardiovascular disease mortality. Hypertension. 2002;40:458\u201363.","journal-title":"Hypertension"}],"container-title":["Journal of Anesthesia"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00540-019-02672-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00540-019-02672-y\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00540-019-02672-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,8,10]],"date-time":"2021-08-10T10:27:32Z","timestamp":1628591252000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00540-019-02672-y"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,8,17]]},"references-count":28,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2019,10]]}},"alternative-id":["2672"],"URL":"https:\/\/doi.org\/10.1007\/s00540-019-02672-y","relation":{},"ISSN":["0913-8668","1438-8359"],"issn-type":[{"value":"0913-8668","type":"print"},{"value":"1438-8359","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,8,17]]},"assertion":[{"value":"29 March 2019","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"8 August 2019","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"17 August 2019","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"The authors declare no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}