{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,2]],"date-time":"2025-08-02T05:21:22Z","timestamp":1754112082408,"version":"3.37.3"},"reference-count":14,"publisher":"Springer Science and Business Media LLC","issue":"5","license":[{"start":{"date-parts":[[2020,7,12]],"date-time":"2020-07-12T00:00:00Z","timestamp":1594512000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2020,7,12]],"date-time":"2020-07-12T00:00:00Z","timestamp":1594512000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Anesth"],"published-print":{"date-parts":[[2020,10]]},"DOI":"10.1007\/s00540-020-02824-5","type":"journal-article","created":{"date-parts":[[2020,7,12]],"date-time":"2020-07-12T09:02:25Z","timestamp":1594544545000},"page":"786-789","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Individual pharmacometric analysis for sugammadex reversal and re-administration of neuromuscular blockade"],"prefix":"10.1007","volume":"34","author":[{"given":"Yuki","family":"Kashima","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4702-9874","authenticated-orcid":false,"given":"Kenichi","family":"Masui","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2020,7,12]]},"reference":[{"key":"2824_CR1","doi-asserted-by":"publisher","first-page":"115","DOI":"10.1093\/bja\/aep093","volume":"103","author":"A Srivastava","year":"2009","unstructured":"Srivastava A, Hunter JM. Reversal of neuromuscular block. Br J Anaesth. 2009;103:115\u201329.","journal-title":"Br J Anaesth"},{"key":"2824_CR2","doi-asserted-by":"publisher","first-page":"31","DOI":"10.1111\/j.1365-2044.2008.05868.x","volume":"64","author":"LHDJ Booij","year":"2009","unstructured":"Booij LHDJ. Cyclodextrins and the emergence of sugammadex. Anesthesia. 2009;64:31\u20137.","journal-title":"Anesthesia"},{"key":"2824_CR3","first-page":"49","volume":"64","author":"PE Dubois","year":"2013","unstructured":"Dubois PE, Mulier JP. A review of the interest of sugammadex for deep neuromuscular blockade management in Belgium. Acta Anaesth Belg. 2013;64:49\u201360.","journal-title":"Acta Anaesth Belg"},{"key":"2824_CR4","doi-asserted-by":"publisher","first-page":"166","DOI":"10.1016\/j.jclinane.2016.11.004","volume":"37","author":"T Askin","year":"2017","unstructured":"Askin T, Unver S, Oguz D, Kutay K. Case report: Neuromuscular block induced by rocuronium following sugammadex administration. J Clin Anesth. 2017;37:166\u20137.","journal-title":"J Clin Anesth"},{"key":"2824_CR5","doi-asserted-by":"publisher","first-page":"43","DOI":"10.4097\/kjae.2014.67.1.43","volume":"67","author":"H-J Lee","year":"2014","unstructured":"Lee H-J, Kim KS, Kim TY, Lee JH, Jeong M. The use of 3 sugammadex out of 5 reversal of during recovery of rocuronium-induced neuromuscular blockade in a patient with post-tonsillectomy hemorrhage -a case report-. Korean J Anesthesiol. 2014;67:43\u20137.","journal-title":"Korean J Anesthesiol"},{"key":"2824_CR6","doi-asserted-by":"publisher","first-page":"188","DOI":"10.1097\/ALN.0b013e31817f5bc7","volume":"109","author":"FK P\u00fchringer","year":"2008","unstructured":"P\u00fchringer FK, Rex C, Sielenk\u00e4mper AW, Claudius C, Larsen PB, Prins ME. Reversal of profound, high-dose rocuronium-induced neuromuscular blockade by sugammadex at two different time points: an international, multicenter, randomized, dose-finding, safety assessor-blinded, phase II trial. Anesthesiology. 2008;109:188\u201397.","journal-title":"Anesthesiology"},{"key":"2824_CR7","doi-asserted-by":"publisher","first-page":"534","DOI":"10.1007\/s00540-016-2159-4","volume":"30","author":"H Iwasaki","year":"2016","unstructured":"Iwasaki H, Sasakawa T, Takahoko K, Takagi S, Nakatsuka H, Suzuki T, Iwasaki H. A case series of re-establishment of neuromuscular block with rocuronium after sugammadex reversal. J Anesth. 2016;30:534\u20137.","journal-title":"J Anesth"},{"key":"2824_CR8","doi-asserted-by":"publisher","first-page":"239","DOI":"10.1097\/01.anes.0000270722.95764.37","volume":"107","author":"HD de Boer","year":"2007","unstructured":"de Boer HD, Driessen JJ, Marcus MA, Kerkkamp H, Heeringa M, Klimek M. Reversal of rocuronium-induced (1.2 mg\/kg) profound neuromuscular block by sugammadex: a multicenter, dose-finding and safety study. Anesthesiology. 2007;107:239\u201344.","journal-title":"Anesthesiology"},{"key":"2824_CR9","doi-asserted-by":"publisher","first-page":"373","DOI":"10.1093\/bja\/aem402","volume":"100","author":"G Cammu","year":"2008","unstructured":"Cammu G, De Kam PH, Demeyer I, Decoopman M, Peeters PAM, Smeets JMW, Foubert L. Safety and tolerability of single intravenous doses of sugammadex administered simultaneously with rocuronium or vecuronium in healthy volunteers. Br J Anaesth. 2008;100:373\u20139.","journal-title":"Br J Anaesth"},{"key":"2824_CR10","doi-asserted-by":"publisher","first-page":"415","DOI":"10.1111\/j.1365-2125.2011.04000.x","volume":"72","author":"HJ Kleijn","year":"2011","unstructured":"Kleijn HJ, Zollinger DP, van den Heuvel MW, Kersbusch T. Population pharmacokinetic-pharmacodynamic analysis for sugammadex-mediated reversal of rocuronium-induced neuromuscular blockade. Br J Clin Pharmacol. 2011;72:415\u201333.","journal-title":"Br J Clin Pharmacol"},{"key":"2824_CR11","doi-asserted-by":"publisher","first-page":"709","DOI":"10.1007\/s00540-018-2543-3","volume":"32","author":"K Masui","year":"2018","unstructured":"Masui K, Ishigaki S, Tomita A, Otake H. Rocuronium pharmacodynamic models for published five pharmacokinetic models: age and sex are covariates in pharmacodynamic models. J Anesth. 2018;32:709\u201316.","journal-title":"J Anesth"},{"key":"2824_CR12","doi-asserted-by":"publisher","first-page":"631","DOI":"10.1097\/00000542-200604000-00003","volume":"104","author":"AF Kopman","year":"2006","unstructured":"Kopman AF. Sugammadex: A revolutionary approach to neuromuscular antagonism. Anesthesiology. 2006;104:631\u20133.","journal-title":"Anesthesiology"},{"key":"2824_CR13","doi-asserted-by":"publisher","first-page":"1","DOI":"10.4097\/kjae.2014.67.1.1","volume":"67","author":"YH Kim","year":"2014","unstructured":"Kim YH. Repeat dosing of rocuronium-sugammadex: unpredictable. Korean J Anesthesiol. 2014;67:1\u20133.","journal-title":"Korean J Anesthesiol"},{"key":"2824_CR14","doi-asserted-by":"publisher","first-page":"487","DOI":"10.1093\/bja\/aeq167","volume":"105","author":"G Cammu","year":"2010","unstructured":"Cammu G, de Kam PJ, De Graeve K, van den Heuevel M, Suy K, Morias K, Foubert L, Grobara P, Peeters P. Repeat dosing of rocuronium 1.2 mg kg-1 after reversal of neuromuscular block by sugammadex 4.0 mg kg-1 in anaesthetized healthy volunteers: a modelling-based pilot study. Br J Anaesth. 2010;105:487\u201392.","journal-title":"Br J Anaesth"}],"container-title":["Journal of Anesthesia"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00540-020-02824-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00540-020-02824-5\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00540-020-02824-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,7,11]],"date-time":"2021-07-11T23:19:41Z","timestamp":1626045581000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00540-020-02824-5"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,7,12]]},"references-count":14,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2020,10]]}},"alternative-id":["2824"],"URL":"https:\/\/doi.org\/10.1007\/s00540-020-02824-5","relation":{},"ISSN":["0913-8668","1438-8359"],"issn-type":[{"type":"print","value":"0913-8668"},{"type":"electronic","value":"1438-8359"}],"subject":[],"published":{"date-parts":[[2020,7,12]]},"assertion":[{"value":"30 May 2020","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"4 July 2020","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"12 July 2020","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"Support for this study was solely provided by departmental and institutional funding of Department of Anesthesiology, Showa University School of Medicine, Tokyo, Japan. The authors have no other conflict of interest for this manuscript.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}