{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T15:38:53Z","timestamp":1790782733415,"version":"4.1.0"},"reference-count":14,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[2023,6,6]],"date-time":"2023-06-06T00:00:00Z","timestamp":1686009600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2023,6,6]],"date-time":"2023-06-06T00:00:00Z","timestamp":1686009600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Anesth"],"published-print":{"date-parts":[[2023,8]]},"DOI":"10.1007\/s00540-023-03209-0","type":"journal-article","created":{"date-parts":[[2023,6,6]],"date-time":"2023-06-06T19:11:18Z","timestamp":1686078678000},"page":"641-644","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Chronological changes in plasma levobupivacaine concentrations after bilateral modified thoracoabdominal nerve block through perichondrial approach"],"prefix":"10.1007","volume":"37","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0871-3956","authenticated-orcid":false,"given":"Katsuhiro","family":"Aikawa","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuka","family":"Uchinami","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuji","family":"Morimoto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2023,6,6]]},"reference":[{"issue":"3","key":"3209_CR1","doi-asserted-by":"publisher","first-page":"330","DOI":"10.1007\/s12630-015-0564-z","volume":"63","author":"K El-Boghdadly","year":"2016","unstructured":"El-Boghdadly K, Chin KJ. Local anesthetic systemic toxicity: Continuing professional development. Can J Anaesth. 2016;63(3):330\u201349.","journal-title":"Can J Anaesth"},{"issue":"6","key":"3209_CR2","doi-asserted-by":"publisher","first-page":"996","DOI":"10.1093\/bja\/aet015","volume":"110","author":"JD Griffiths","year":"2013","unstructured":"Griffiths JD, Le NV, Grant S, Bjorksten A, Hebbard P, Royse C. Symptomatic local anaesthetic toxicity and plasma ropivacaine concentrations after transversus abdominis plane block for Caesarean section. Br J Anaesth. 2013;110(6):996\u20131000.","journal-title":"Br J Anaesth"},{"issue":"3","key":"3209_CR3","doi-asserted-by":"publisher","first-page":"194","DOI":"10.1136\/rapm-2021-102984","volume":"47","author":"JD Turner","year":"2022","unstructured":"Turner JD, Cortese KT, Kim ST, McKee ZL, Jaffe D, Henshaw DS, Dobson SW, Weller R, Edwards CJ, Reynolds JW, Russell G. Mean plasma bupivacaine concentrations following pectoral nerve blocks (PECS II). Reg Anesth Pain Med. 2022;47(3):194\u20135.","journal-title":"Reg Anesth Pain Med"},{"issue":"6","key":"3209_CR4","doi-asserted-by":"publisher","first-page":"633","DOI":"10.1097\/AAP.0b013e31826c330a","volume":"37","author":"MA Corvetto","year":"2012","unstructured":"Corvetto MA, Echevarr\u00eda GC, De La Fuente N, Mosqueira L, Solari S, Altermatt FR. Comparison of plasma concentrations of levobupivacaine with and without epinephrine for transversus abdominis plane block. Reg Anesth Pain Med. 2012;37(6):633\u20137.","journal-title":"Reg Anesth Pain Med"},{"key":"3209_CR5","doi-asserted-by":"publisher","first-page":"109","DOI":"10.1016\/j.jclinane.2019.01.003","volume":"55","author":"S Tulgar","year":"2019","unstructured":"Tulgar S, Selvi O, Thomas DT, Deveci U, \u00d6zer Z. Modified thoracoabdominal nerves block through perichondrial approach (M-TAPA) provides effective analgesia in abdominal surgery and is a choice for opioid sparing anesthesia. J Clin Anesth. 2019;55:109.","journal-title":"J Clin Anesth"},{"issue":"2","key":"3209_CR6","doi-asserted-by":"publisher","first-page":"134","DOI":"10.1136\/rapm-2021-102870","volume":"47","author":"K Aikawa","year":"2022","unstructured":"Aikawa K, Yokota I, Maeda Y, Morimoto Y. Evaluation of sensory loss obtained by modified-thoracoabdominal nerves block through perichondrial approach in patients undergoing gynecological laparoscopic surgery: a prospective observational study. Reg Anesth Pain Med. 2022;47(2):134\u20135.","journal-title":"Reg Anesth Pain Med"},{"key":"3209_CR7","doi-asserted-by":"crossref","unstructured":"Sawada A, Kumita S, Nitta A, Ohsaki Y, Yamakage M. Modified thoracoabdominal nerve block through perichondrial approach (M-TAPA): an anatomical study to evaluate the spread of dye after a simulated injection in soft embalmed Thiel cadavers. Reg Anesth Pain Med. 2023:1\u20135. (Online ahead of print).","DOI":"10.1136\/rapm-2022-104275"},{"issue":"2","key":"3209_CR8","doi-asserted-by":"publisher","first-page":"254","DOI":"10.1007\/s00540-022-03158-0","volume":"37","author":"H G\u00fcng\u00f6r","year":"2022","unstructured":"G\u00fcng\u00f6r H, Ciftci B, Alver S, G\u00f6lboyu BE, Ozdenkaya Y, Tulgar S. Modified thoracoabdominal nerve block through perichondrial approach (M-TAPA) vs local infiltration for pain management after laparoscopic cholecystectomy surgery: a randomized study. J Anesth. 2022;37(2):254\u201360.","journal-title":"J Anesth."},{"issue":"3","key":"3209_CR9","doi-asserted-by":"publisher","first-page":"245","DOI":"10.1046\/j.1365-2125.1998.00775.x","volume":"46","author":"H Bardsley","year":"1998","unstructured":"Bardsley H, Gristwood R, Baker H, Watson N, Nimmo W. A comparison of the cardiovascular effects of levobupivacaine and rac-bupivacaine following intravenous administration to healthy volunteers. Br J Clin Pharmacol. 1998;46(3):245\u20139.","journal-title":"Br J Clin Pharmacol"},{"key":"3209_CR10","doi-asserted-by":"publisher","first-page":"8","DOI":"10.1016\/j.jclinane.2018.10.015","volume":"54","author":"S Tulgar","year":"2019","unstructured":"Tulgar S, Senturk O, Selvi O, Balaban O, Ahiskalio\u011flu A, Thomas DT, Ozer Z. Perichondral approach for blockage of thoracoabdominal nerves: Anatomical basis and clinical experience in three cases. J Clin Anesth. 2019;54:8\u201310.","journal-title":"J Clin Anesth"},{"issue":"3","key":"3209_CR11","doi-asserted-by":"publisher","first-page":"326","DOI":"10.1136\/rapm-2018-100021","volume":"44","author":"K Hida","year":"2019","unstructured":"Hida K, Murata H, Ichinomiya T, Inoue H, Sato S, Hara T. Effects of programmed intermittent thoracic paravertebral bolus of levobupivacaine on the spread of sensory block: a randomized, controlled, double-blind study. Reg Anesth Pain Med. 2019;44(3):326\u201332.","journal-title":"Reg Anesth Pain Med"},{"issue":"4","key":"3209_CR12","doi-asserted-by":"publisher","first-page":"357","DOI":"10.4097\/kja.22137","volume":"75","author":"B Ciftci","year":"2022","unstructured":"Ciftci B, Alici HA, Ansen G, Sakul BU, Tulgar S. Cadaveric investigation of the spread of the thoracoabdominal nerve block using the perichondral and modified perichondral approaches. Korean J Anesthesiol. 2022;75(4):357\u20139.","journal-title":"Korean J Anesthesiol"},{"issue":"2","key":"3209_CR13","doi-asserted-by":"publisher","first-page":"469","DOI":"10.1016\/j.bja.2018.02.070","volume":"121","author":"HJ Lacassie","year":"2018","unstructured":"Lacassie HJ, Rolle A, Cort\u00ednez LI, Solari S, Corvetto MA, Altermatt FR. Pharmacokinetics of levobupivacaine with epinephrine in transversus abdominis plane block for postoperative analgesia after Caesarean section. Br J Anaesth. 2018;121(2):469\u201375.","journal-title":"Br J Anaesth"},{"issue":"3","key":"3209_CR14","doi-asserted-by":"publisher","first-page":"294","DOI":"10.1097\/AAP.0b013e31824c20a9","volume":"37","author":"J B\u00f8rglum","year":"2012","unstructured":"B\u00f8rglum J, Jensen K, Christensen AF, Hoegberg LC, Johansen SS, L\u00f6nnqvist PA, Jansen T. Distribution patterns, dermatomal anesthesia, and ropivacaine serum concentrations after bilateral dual transversus abdominis plane block. Reg Anesth Pain Med. 2012;37(3):294\u2013301.","journal-title":"Reg Anesth Pain Med"}],"container-title":["Journal of Anesthesia"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00540-023-03209-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00540-023-03209-0\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00540-023-03209-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,7,31]],"date-time":"2023-07-31T07:07:04Z","timestamp":1690787224000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00540-023-03209-0"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,6,6]]},"references-count":14,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2023,8]]}},"alternative-id":["3209"],"URL":"https:\/\/doi.org\/10.1007\/s00540-023-03209-0","relation":{},"ISSN":["0913-8668","1438-8359"],"issn-type":[{"value":"0913-8668","type":"print"},{"value":"1438-8359","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,6,6]]},"assertion":[{"value":"11 April 2023","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"24 May 2023","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"6 June 2023","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Maruishi Pharmaceutical Cooperation (Osaka, Japan), which distributes levobupivacaine in Japan, supported our study by measuring plasma levobupivacaine concentration without any compensation.\u00a0The authors do not have any other conflict of interest to disclose.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}