{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,10]],"date-time":"2026-01-10T20:58:25Z","timestamp":1768078705412,"version":"3.49.0"},"reference-count":49,"publisher":"Springer Science and Business Media LLC","issue":"12","license":[{"start":{"date-parts":[[2015,9,12]],"date-time":"2015-09-12T00:00:00Z","timestamp":1442016000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Eur Spine J"],"published-print":{"date-parts":[[2015,12]]},"DOI":"10.1007\/s00586-015-4228-z","type":"journal-article","created":{"date-parts":[[2015,9,12]],"date-time":"2015-09-12T08:38:05Z","timestamp":1442047085000},"page":"2735-2745","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Polyurethane on titanium unconstrained disc arthroplasty versus anterior discectomy and fusion for the treatment of cervical disc disease: a review of level I\u2013II randomized clinical trials including clinical outcomes"],"prefix":"10.1007","volume":"24","author":[{"given":"Mar\u00eda","family":"Aragon\u00e9s","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eduardo","family":"Hevia","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carlos","family":"Barrios","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2015,9,12]]},"reference":[{"key":"4228_CR1","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1097\/00024720-200404000-00001","volume":"17","author":"J Goffin","year":"2004","unstructured":"Goffin J, Geusens E, Vantomme N et al (2004) Long-term follow-up after interbody fusion of the cervical spine. J Spinal Disord Tech 17:79\u201385","journal-title":"J Spinal Disord Tech"},{"key":"4228_CR2","doi-asserted-by":"crossref","first-page":"1037","DOI":"10.1007\/s00264-008-0571-6","volume":"33","author":"YC Yang","year":"2009","unstructured":"Yang YC, Nie L, Cheng L, Hou Y (2009) Clinical and radiographic reports following cervical arthroplasty: a 24-month follow-up. Int Orthop 33:1037\u20131042","journal-title":"Int Orthop"},{"key":"4228_CR3","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1007\/s00264-006-0287-4","volume":"32","author":"S Peng-Fei","year":"2008","unstructured":"Peng-Fei S, Yu-Hua J (2008) Cervical disc prosthesis replacement and interbody fusion: a comparative study. Int Orthop 32:103\u2013106","journal-title":"Int Orthop"},{"key":"4228_CR4","doi-asserted-by":"crossref","first-page":"519","DOI":"10.2106\/00004623-199904000-00009","volume":"81","author":"AS Hilibrand","year":"1999","unstructured":"Hilibrand AS, Carlson GD, Palumbo MA, Jones PK, Bohlman HH (1999) Radiculopathy and myelopathy at segments adjacent to the site of a previous anterior cervical arthrodesis. J Bone Joint Surg Am 81:519\u2013528","journal-title":"J Bone Joint Surg Am"},{"issue":"Suppl. 2","key":"4228_CR5","doi-asserted-by":"crossref","first-page":"223","DOI":"10.2106\/JBJS.I.00564","volume":"91","author":"JM Buchowski","year":"2009","unstructured":"Buchowski JM, Anderson PA, Sekhon L, Riew KD (2009) Cervical disc arthroplasty compared with arthrodesis for the treatment of myelopathy. Surgical technique. J Bone Joint Surg Am 91(Suppl. 2):223\u2013232","journal-title":"J Bone Joint Surg Am"},{"key":"4228_CR6","doi-asserted-by":"crossref","first-page":"741","DOI":"10.1227\/01.NEU.0000325495.79104.DB","volume":"63","author":"MP Steinmetz","year":"2008","unstructured":"Steinmetz MP, Patel R, Traynelis V, Resnick DK, Anderson PA (2008) Cervical disc arthroplasty compared with fusion in a workers\u2019 compensation population. Neurosurgery 63:741\u2013747 (discussion 747)","journal-title":"Neurosurgery"},{"key":"4228_CR7","doi-asserted-by":"crossref","first-page":"674","DOI":"10.1007\/s00586-011-2094-x","volume":"21","author":"J Chen","year":"2012","unstructured":"Chen J, Wang X, Bai W, Shen X, Yuan W (2012) Prevalence of heterotopic ossification after cervical total disc arthroplasty: a meta-analysis. Eur Spine J 21:674\u2013680","journal-title":"Eur Spine J"},{"key":"4228_CR8","doi-asserted-by":"crossref","first-page":"1153","DOI":"10.1227\/01.NEU.0000369189.09182.5F","volume":"66","author":"RH Bartels","year":"2010","unstructured":"Bartels RH, Donk R, Verbeek AL (2010) No justification for cervical disk prostheses in clinical practice: a meta-analysis of randomized controlled trials. Neurosurgery 66:1153\u20131160 (discussion 1160)","journal-title":"Neurosurgery"},{"key":"4228_CR9","doi-asserted-by":"crossref","first-page":"E6","DOI":"10.1097\/BRS.0b013e31815e5dce","volume":"33","author":"MA Rousseau","year":"2008","unstructured":"Rousseau MA, Cottin P, Levante S, Nogier A, Lazennec JY, Skalli W (2008) In vivo kinematics of two types of ball-and-socket cervical disc replacements in the sagittal plane: cranial versus caudal geometric center. Spine 33:E6\u2013E9","journal-title":"Spine"},{"key":"4228_CR10","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3171\/2010.3.FOCUS1058","volume":"28","author":"BC Lazaro","year":"2010","unstructured":"Lazaro BC, Yucesoy K, Yuksel KZ, Kowalczyk I, Rabin D, Fink M, Duggal N (2010) Effect of arthroplasty design on cervical spine kinematics: analysis of the Bryan Disc, ProDisc-C, and Synergy disc. Neurosurg Focus 28:1\u20138","journal-title":"Neurosurg Focus"},{"key":"4228_CR11","doi-asserted-by":"crossref","first-page":"E285","DOI":"10.1097\/BRS.0b013e3181c88165","volume":"35","author":"JJ Park","year":"2010","unstructured":"Park JJ, Quirno M, Cunningham MR et al (2010) Analysis of segmental cervical spine vertebral motion after prodisc-C cervical disc replacement. Spine 35:E285\u2013E289","journal-title":"Spine"},{"key":"4228_CR12","doi-asserted-by":"crossref","first-page":"630","DOI":"10.3171\/2011.8.SPINE11273","volume":"15","author":"I Kowalczyk","year":"2011","unstructured":"Kowalczyk I, Lazaro BC, Fink M, Rabin D, Duggal N (2011) Analysis of in vivo kinematics of 3 different cervical devices: Bryan disc, ProDisc-C, and Prestige LP disc. J Neurosurg Spine 15:630\u2013635","journal-title":"J Neurosurg Spine"},{"key":"4228_CR13","doi-asserted-by":"crossref","first-page":"E158","DOI":"10.1097\/BSD.0b013e31828bc02f","volume":"26","author":"Y Chen","year":"2013","unstructured":"Chen Y, Yuan W, Wu X et al (2013) The effect of range of motion after single-level discover cervical artificial disk replacement. J Spinal Disord Tech 26:E158\u2013E162","journal-title":"J Spinal Disord Tech"},{"key":"4228_CR14","doi-asserted-by":"crossref","first-page":"628","DOI":"10.1016\/j.spinee.2013.02.046","volume":"13","author":"WH Ryu","year":"2013","unstructured":"Ryu WH, Kowalczyk I, Duggal N (2013) Long-term kinematic analysis of cervical spine after single-level implantation of Bryan cervical disc prosthesis. Spine J 13:628\u2013634","journal-title":"Spine J"},{"key":"4228_CR15","doi-asserted-by":"crossref","first-page":"303S","DOI":"10.1016\/j.spinee.2004.07.026","volume":"4","author":"PA Anderson","year":"2004","unstructured":"Anderson PA, Sasso RC, Rouleau JP, Carlson CS, Goffin J (2004) The Bryan Cervical Disc: wear properties and early clinical results. Spine J 4:303S\u2013309S","journal-title":"Spine J"},{"key":"4228_CR16","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1016\/j.nec.2005.06.003","volume":"16","author":"S Papadopoulos","year":"2005","unstructured":"Papadopoulos S (2005) The Bryan cervical disc system. Neurosurg Clin North Am 16:629\u2013636","journal-title":"Neurosurg Clin North Am"},{"key":"4228_CR17","doi-asserted-by":"crossref","first-page":"b2535","DOI":"10.1136\/bmj.b2535","volume":"339","author":"D Moher","year":"2009","unstructured":"Moher D, Liberati A, Tetzlaff J, Altman DG, The PRISMA Group (2009) Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. BMJ 339:b2535. doi: 10.1136\/bmj.b2535","journal-title":"BMJ"},{"key":"4228_CR18","unstructured":"Oxford Centre for Evidence-Based Medicine. http:\/\/www.cebm.net\/levelsofevidence.asp#levels"},{"key":"4228_CR19","volume-title":"Systematic reviews in healthcare","author":"C Lefebvre","year":"2001","unstructured":"Lefebvre C, Clarke MJ (2001) Identifying randomised trials. In: Egger M, Smith D, Altman DG (eds) Systematic reviews in healthcare, 2nd edn. BMJ Publishing Group, London","edition":"2"},{"key":"4228_CR20","first-page":"477","volume":"170","author":"M Bhandari","year":"2004","unstructured":"Bhandari M, Busse JW, Jackowski D et al (2004) Association between industry funding and statistically significant pro-industry findings in medical and surgical randomized trials. CMAJ 170:477\u2013480","journal-title":"CMAJ"},{"key":"4228_CR21","unstructured":"Higgins JPT, Altman DG, Sterne JAC (2011) Assessing risk of bias in included studies. In: Higgins JPT, Green S (eds) Cochrane handbook for systematic reviews of interventions version 510 (updated March 2011). The Cochrane Collaboration"},{"key":"4228_CR22","first-page":"409","volume":"14","author":"H Vernon","year":"1991","unstructured":"Vernon H, Mior S (1991) The Neck Disability Index: a study of reliability and validity. J Manipulative Physiol Ther 14:409\u2013415","journal-title":"J Manipulative Physiol Ther"},{"key":"4228_CR23","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1016\/j.spinee.2010.02.007","volume":"10","author":"LY Carreon","year":"2010","unstructured":"Carreon LY, Glassman SD, Campbell MJ, Anderson PA (2010) Neck Disability Index, short form-36 physical component summary, and pain scales for neck and arm pain: the minimum clinically important difference and substantial clinical benefit after cervical spine fusion. Spine J 10:469\u2013474","journal-title":"Spine J"},{"key":"4228_CR24","doi-asserted-by":"crossref","first-page":"424","DOI":"10.3171\/spi.2005.3.6.0424","volume":"3","author":"RJ Hacker","year":"2005","unstructured":"Hacker RJ (2005) Cervical disc arthroplasty: a controlled randomized prospective study with intermediate follow-up results. J Neurosurg Spine 3:424\u2013428","journal-title":"J Neurosurg Spine"},{"key":"4228_CR25","doi-asserted-by":"crossref","first-page":"1347","DOI":"10.1007\/s00264-008-0655-3","volume":"33","author":"L Cheng","year":"2009","unstructured":"Cheng L, Nie L, Zhang L, Hou Y (2009) Fusion versus Bryan Cervical Disc in two-level cervical disc disease: a prospective, randomised study. Int Orthop 33:1347\u20131351","journal-title":"Int Orthop"},{"key":"4228_CR26","doi-asserted-by":"crossref","first-page":"2354","DOI":"10.2106\/JBJS.G.01608","volume":"90","author":"KD Riew","year":"2008","unstructured":"Riew KD, Buchowski JM, Sasso R et al (2008) Cervical disc arthroplasty compared with arthrodesis for the treatment of myelopathy. J Bone Joint Surg Am 90:2354\u20132364","journal-title":"J Bone Joint Surg Am"},{"key":"4228_CR27","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1007\/s00586-008-0854-z","volume":"18","author":"SW Kim","year":"2009","unstructured":"Kim SW, Limson MA, Kim SB et al (2009) Comparison of radiographic changes after ACDF versus Bryan disc arthroplasty in single and bi-level cases. Eur Spine J 18:218\u2013231","journal-title":"Eur Spine J"},{"key":"4228_CR28","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1097\/BSD.0b013e3181bb8568","volume":"23","author":"BJ Garrido","year":"2010","unstructured":"Garrido BJ, Taha TA, Sasso RC (2010) Clinical outcomes of Bryan cervical disc arthroplasty a prospective, randomized, controlled, single site trial with 48-month follow-up. J Spinal Disord Tech 23:367\u2013371","journal-title":"J Spinal Disord Tech"},{"key":"4228_CR29","doi-asserted-by":"crossref","first-page":"715","DOI":"10.3171\/2010.5.SPINE09852","volume":"13","author":"D Coric","year":"2010","unstructured":"Coric D, Cassis J, Carew JD, Boltes MO (2010) Prospective study of cervical arthroplasty in 98 patients involved in 1 of 3 separate investigational device exemption studies from a single investigational site with a minimum 2-year follow-up: clinical article. J Neurosurg Spine 13:715\u2013721","journal-title":"J Neurosurg Spine"},{"key":"4228_CR30","doi-asserted-by":"crossref","first-page":"3408","DOI":"10.1007\/s11999-011-2039-z","volume":"469","author":"L Cheng","year":"2011","unstructured":"Cheng L, Nie L, Li M, Huo Y, Pan X (2011) Superiority of the BRYAN(\u00ae) disc prosthesis for cervical myelopathy: a randomized study with 3-year follow-up. Clin Orthop Relat Res 469:3408\u20133414","journal-title":"Clin Orthop Relat Res"},{"key":"4228_CR31","doi-asserted-by":"crossref","first-page":"1684","DOI":"10.2106\/JBJS.J.00476","volume":"93","author":"RC Sasso","year":"2011","unstructured":"Sasso RC, Anderson PA, Riew KD, Heller JG (2011) Results of cervical arthroplasty compared with anterior discectomy and fusion: four-year clinical outcomes in a prospective randomized controlled trial. J Bone Joint Surg Am 93:1684\u20131692","journal-title":"J Bone Joint Surg Am"},{"key":"4228_CR32","first-page":"3939","volume":"125","author":"Y Sun","year":"2012","unstructured":"Sun Y, Zhao YB, Pan SF, Zhou FF et al (2012) Comparison of adjacent segment degeneration five years after single level cervical fusion and cervical arthroplasty: a retrospective controlled study. Chin Med J 125:3939\u20133941","journal-title":"Chin Med J"},{"key":"4228_CR33","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1097\/BRS.0b013e31822699fa","volume":"37","author":"X Zhang","year":"2012","unstructured":"Zhang X, Zhang X, Chen C et al (2012) Randomized, controlled multicenter, clinical trial comparing BRYAN cervical disc arthroplasty with anterior cervical decompression and fusion in China. Spine 37:433\u2013438","journal-title":"Spine"},{"key":"4228_CR34","doi-asserted-by":"crossref","first-page":"831","DOI":"10.1097\/PHM.0b013e3181ec98e6","volume":"89","author":"IA Young","year":"2010","unstructured":"Young IA, Cleland JA, Michener LA, Brown C (2010) Reliability, construct validity, and responsiveness of the neck disability index, patient-specific functional scale, and numeric pain rating scale in patients with cervical radiculopathy. Am J Phys Med Rehabil 89:831\u2013839","journal-title":"Am J Phys Med Rehabil"},{"key":"4228_CR35","doi-asserted-by":"crossref","first-page":"2231","DOI":"10.1016\/j.spinee.2014.03.047","volume":"14","author":"MD Alvin","year":"2014","unstructured":"Alvin MD, Abbott E, Lubelski D et al (2014) Cervical arthroplasty: a critical review of the literature. Spine J 14:2231\u20132245","journal-title":"Spine J"},{"key":"4228_CR36","doi-asserted-by":"crossref","first-page":"1904","DOI":"10.1007\/s11999-013-2830-0","volume":"471","author":"S Yin","year":"2013","unstructured":"Yin S, Yu X, Zhou S, Yin Z, Qiu Y (2013) Is cervical disc arthroplasty superior to fusion for treatment of symptomatic cervical disc disease? A meta-analysis. Clin Orthop Relat Res 471:1904\u20131919","journal-title":"Clin Orthop Relat Res"},{"key":"4228_CR37","doi-asserted-by":"crossref","first-page":"943","DOI":"10.1097\/BRS.0b013e31823da169","volume":"37","author":"PC McAfee","year":"2012","unstructured":"McAfee PC, Reah C, Gilder K, Eisermann L, Cunningham B (2012) A meta-analysis of comparative outcomes following cervical arthroplasty or anterior cervical fusion: results from 4 prospective multicenter randomized clinical trials and up to 1226 patients. Spine 37:943\u2013952","journal-title":"Spine"},{"key":"4228_CR38","doi-asserted-by":"crossref","first-page":"2431","DOI":"10.1097\/00007632-200211150-00003","volume":"27","author":"JC Eck","year":"2002","unstructured":"Eck JC, Humphreys SC, Lim TH et al (2002) Biomechanical study on the effect of cervical spine fusion on adjacent-level intradiscal pressure and segmental motion. Spine 27:2431\u20132434","journal-title":"Spine"},{"key":"4228_CR39","doi-asserted-by":"crossref","first-page":"1677","DOI":"10.1007\/s00264-008-0684-y","volume":"33","author":"S Ruetten","year":"2009","unstructured":"Ruetten S, Komp M, Merk H, Godolias G (2009) Full-endoscopic anterior decompression versus conventional anterior decompression and fusion in cervical disc herniations. Int Orthop 33:1677\u20131682","journal-title":"Int Orthop"},{"key":"4228_CR40","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1007\/s00264-007-0378-x","volume":"32","author":"JC Liao","year":"2008","unstructured":"Liao JC, Niu CC, Chen WJ, Chen LH (2008) Polyetheretherketone (PEEK) cage filled with cancellous allograft in anterior cervical discectomy and fusion. Int Orthop 32:643\u2013648","journal-title":"Int Orthop"},{"key":"4228_CR41","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1097\/BRS.0b013e31818ee263","volume":"34","author":"JG Heller","year":"2009","unstructured":"Heller JG, Sasso RC, Papadopoulos SM et al (2009) Comparison of BRYAN cervical disc arthroplasty with anterior cervical decompression and fusion: clinical and radiographic results of a randomized, controlled, clinical trial. Spine 34:101\u2013107","journal-title":"Spine"},{"key":"4228_CR42","doi-asserted-by":"crossref","first-page":"1305","DOI":"10.1097\/BRS.0b013e31817329a1","volume":"33","author":"PA Anderson","year":"2008","unstructured":"Anderson PA, Sasso RC, Riew KD (2008) Comparison of adverse events between the Bryan artificial cervical disc and anterior cervical arthrodesis. Spine 33:1305\u20131312","journal-title":"Spine"},{"key":"4228_CR43","doi-asserted-by":"crossref","first-page":"555","DOI":"10.2106\/JBJS.K.00599","volume":"95","author":"Y Gao","year":"2013","unstructured":"Gao Y, Liu M, Li T, Huang F, Tang T, Xiang Z (2013) A meta-analysis comparing the results of cervical disc arthroplasty with anterior cervical discectomy and fusion (ACDF) for the treatment of symptomatic cervical disc disease. J Bone Joint Surg Am 95:555\u2013561","journal-title":"J Bone Joint Surg Am"},{"key":"4228_CR44","doi-asserted-by":"crossref","first-page":"1048","DOI":"10.1016\/j.spinee.2013.02.036","volume":"13","author":"S Yi","year":"2013","unstructured":"Yi S, Shin DA, Kim KN (2013) The predisposing factors for the heterotopic ossification after cervical artificial disc replacement. Spine J 13:1048\u20131054","journal-title":"Spine J"},{"key":"4228_CR45","doi-asserted-by":"crossref","first-page":"1556","DOI":"10.1097\/BRS.0b013e3181c6526b","volume":"35","author":"S Yi","year":"2010","unstructured":"Yi S, Kim KN, Yang MS (2010) Difference in occurrence of heterotopic ossification according to prosthesis type in the cervical artificial disc replacement. Spine 35:1556\u20131561","journal-title":"Spine"},{"key":"4228_CR46","doi-asserted-by":"crossref","first-page":"98","DOI":"10.3171\/spi.2006.4.2.98","volume":"4","author":"GE Pickett","year":"2006","unstructured":"Pickett GE, Sekhon LH, Sears WR, Duggal N (2006) Complications with cervical arthroplasty. J Neurosurg Spine 4:98\u2013105","journal-title":"J Neurosurg Spine"},{"key":"4228_CR47","doi-asserted-by":"crossref","first-page":"921","DOI":"10.1177\/000348940311201102","volume":"112","author":"EM Baron","year":"2003","unstructured":"Baron EM, Soliman AM, Gaughan JP et al (2003) Dysphagia, hoarseness, and unilateral true vocal fold motion impairment following anterior cervical diskectomy and fusion. Ann Otol Rhinol Laryngol 112:921\u2013926","journal-title":"Ann Otol Rhinol Laryngol"},{"key":"4228_CR48","author":"SV Nandyala","year":"2014","unstructured":"Nandyala SV, Marquez-Lara A, Fineberg SJ, Singh K (2014) Comparison of revision surgeries for one- to two-level cervical TDR and ACDF from 2002 to 2011. Spine J. doi: 10.1016\/j.spinee.2014.03.037","journal-title":"Spine J"},{"key":"4228_CR49","doi-asserted-by":"crossref","first-page":"940","DOI":"10.1097\/BRS.0b013e31816c8b67","volume":"33","author":"S Ruetten","year":"2008","unstructured":"Ruetten S, Komp M, Merk H, Godolias G (2008) Full-endoscopic cervical posterior foraminotomy for the operation of lateral disc herniations using 5.9-mm endoscopes: a prospective, randomized, controlled study. Spine 33:940\u2013948","journal-title":"Spine"}],"container-title":["European Spine Journal"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00586-015-4228-z.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00586-015-4228-z\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00586-015-4228-z","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,29]],"date-time":"2019-05-29T03:37:40Z","timestamp":1559101060000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00586-015-4228-z"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,9,12]]},"references-count":49,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2015,12]]}},"alternative-id":["4228"],"URL":"https:\/\/doi.org\/10.1007\/s00586-015-4228-z","relation":{},"ISSN":["0940-6719","1432-0932"],"issn-type":[{"value":"0940-6719","type":"print"},{"value":"1432-0932","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,9,12]]}}}