{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T15:25:40Z","timestamp":1786980340303,"version":"build-2736575974"},"reference-count":40,"publisher":"Springer Science and Business Media LLC","issue":"7","license":[{"start":{"date-parts":[[2016,1,28]],"date-time":"2016-01-28T00:00:00Z","timestamp":1453939200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"funder":[{"name":"National Key Clinical Department"},{"DOI":"10.13039\/501100001809","name":"the National Natural Science Foundation","doi-asserted-by":"crossref","award":["81371912"],"award-info":[{"award-number":["81371912"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Eur Spine J"],"published-print":{"date-parts":[[2016,7]]},"DOI":"10.1007\/s00586-016-4410-y","type":"journal-article","created":{"date-parts":[[2016,1,28]],"date-time":"2016-01-28T06:33:02Z","timestamp":1453962782000},"page":"2202-2209","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":37,"title":["Morphometric features of posterior cranial fossa are different between Chiari I malformation with and without syringomyelia"],"prefix":"10.1007","volume":"25","author":[{"given":"Huang","family":"Yan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiao","family":"Han","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mengran","family":"Jin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhen","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dingding","family":"Xie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shifu","family":"Sha","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yong","family":"Qiu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zezhang","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2016,1,28]]},"reference":[{"issue":"1\u20132","key":"4410_CR1","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/j.jns.2004.01.014","volume":"220","author":"DN Levine","year":"2004","unstructured":"Levine DN (2004) The pathogenesis of syrinx associated with lesions at the foramen magnum: a critical review of existing theories and proposal of a new hypothesis. J Neurol Sci 220(1\u20132):3\u201321","journal-title":"J Neurol Sci"},{"issue":"3","key":"4410_CR2","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1136\/jnnp.74.3.344","volume":"74","author":"HS Chang","year":"2003","unstructured":"Chang HS, Nakagawa H (2003) Hypothesis on the pathophysiology of syrinx based on simulation of cerebrospinal fluid dynamics. J Neurol Neurosurg Psychiatry 74(3):344\u2013347","journal-title":"J Neurol Neurosurg Psychiatry"},{"issue":"1","key":"4410_CR3","doi-asserted-by":"crossref","first-page":"40","DOI":"10.3171\/jns.1997.86.1.0040","volume":"86","author":"M Nishikawa","year":"1997","unstructured":"Nishikawa M, Sakamoto H, Hakuba A, Nakanishi N, Inoue Y (1997) Pathogenesis of Chiari malformation: a morphometric study of the posterior cranial fossa. J Neurosurg 86(1):40\u201347","journal-title":"J Neurosurg"},{"issue":"5","key":"4410_CR4","doi-asserted-by":"crossref","first-page":"1005","DOI":"10.1097\/00006123-199905000-00042","volume":"44","author":"TH Milhorat","year":"1999","unstructured":"Milhorat TH, Chou MW, Trinidad EM, Kula RW et al (1999) Chiari I malformation redefined: clinical and radiographic findings for 364 symptomatic patients. Neurosurgery 44(5):1005\u20131017","journal-title":"Neurosurgery"},{"issue":"2","key":"4410_CR5","first-page":"165","volume":"24","author":"LM Levy","year":"2003","unstructured":"Levy LM (2003) MR identification of Chiari pathophysiology by using spatial and temporal CSF flow indices and implications for syrinx. AJNR Am J Neuroradiol 24(2):165\u2013166","journal-title":"AJNR Am J Neuroradiol"},{"issue":"3","key":"4410_CR6","doi-asserted-by":"crossref","first-page":"551","DOI":"10.1016\/j.tvjl.2013.07.014","volume":"198","author":"CJ Driver","year":"2013","unstructured":"Driver CJ, Volk HA, Rusbridge C, Van Ham LM (2013) An update on the pathogenesis of syrinx secondary to Chiari-like malformations in dogs. Veterinary J 198(3):551\u2013559","journal-title":"Veterinary J"},{"issue":"5","key":"4410_CR7","doi-asserted-by":"crossref","first-page":"367","DOI":"10.3171\/2012.8.SPINE111059","volume":"17","author":"JD Heiss","year":"2012","unstructured":"Heiss JD, Snyder K, Peterson MM, Patronas NJ et al (2012) Pathophysiology of primary spinal syrinx. J Neurosurg Spine 17(5):367\u2013380","journal-title":"J Neurosurg Spine"},{"issue":"2\u20133","key":"4410_CR8","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1016\/0022-510X(90)90150-L","volume":"99","author":"A Vega","year":"1990","unstructured":"Vega A, Quintana F, Berciano J (1990) Basichondrocranium anomalies in adult Chiari type I malformation: a morphometric study. J Neurol Sci 99(2\u20133):137\u2013145","journal-title":"J Neurol Sci"},{"issue":"1","key":"4410_CR9","doi-asserted-by":"crossref","first-page":"40","DOI":"10.3171\/jns.1997.86.1.0040","volume":"86","author":"M Nishikawa","year":"1997","unstructured":"Nishikawa M, Sakamoto H, Hakuba A, Nakanishi N, Inoue Y (1997) Pathogenesis of Chiari malformation: a morphometric study of the posterior cranial fossa. J Neurosurg 86(1):40\u201347","journal-title":"J Neurosurg"},{"issue":"2","key":"4410_CR10","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1007\/s007010200020","volume":"144","author":"F Karagoz","year":"2002","unstructured":"Karagoz F, Izgi N, Kapijcijoglu SS (2002) Morphometric measurements of the cranium in patients with Chiari type I malformation and comparison with the normal population. Acta Neurochir (Wien) 144(2):165\u2013171 (discussion 171)","journal-title":"Acta Neurochir (Wien)"},{"issue":"9","key":"4410_CR11","doi-asserted-by":"crossref","first-page":"1758","DOI":"10.3174\/ajnr.A3435","volume":"34","author":"AM Bagci","year":"2013","unstructured":"Bagci AM, Lee SH, Nagornaya N, Green BA, Alperin N (2013) Automated posterior cranial fossa volumetry by MRI: applications to Chiari malformation type I. AJNR Am J Neuroradiol 34(9):1758\u20131763","journal-title":"AJNR Am J Neuroradiol"},{"issue":"4","key":"4410_CR12","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1016\/S0730-725X(96)00383-9","volume":"15","author":"TA Amer","year":"1997","unstructured":"Amer TA, el-Shmam OM (1997) Chiari malformation type I: a new MRI classification. Magn Reson Imaging 15(4):397\u2013403","journal-title":"Magn Reson Imaging"},{"issue":"3","key":"4410_CR13","doi-asserted-by":"crossref","first-page":"452","DOI":"10.1017\/S0317167100011860","volume":"38","author":"JA Dufton","year":"2011","unstructured":"Dufton JA, Habeeb SY, Heran MK, Mikulis DJ, Islam O (2011) Posterior fossa measurements in patients with and without Chiari I malformation. Can J Neurol Sci 38(3):452\u2013455","journal-title":"Can J Neurol Sci"},{"issue":"2","key":"4410_CR14","doi-asserted-by":"crossref","first-page":"p154","DOI":"10.3171\/2012.10.PEDS12177","volume":"11","author":"KJ Sweeney","year":"2013","unstructured":"Sweeney KJ, Caird J, Sattar MT et al (2013) Spinal level of myelomeningocele lesion as a contributing factor in posterior fossa volume, intracranial cerebellar volume, and cerebellar ectopia. J Neurosurg Pediatr 11(2):p154\u2013p159","journal-title":"J Neurosurg Pediatr"},{"issue":"10","key":"4410_CR15","doi-asserted-by":"crossref","first-page":"2021","DOI":"10.3174\/ajnr.A3967","volume":"35","author":"Z Zhu","year":"2014","unstructured":"Zhu Z, Sha S, Sun X, Liu Z, et al (2014) Tapering of the cervical spinal canal in patients with distended or nondistended syringes secondary to chiari type I malformation. AJNR Am J Neuroradiol 35(10):2021\u20132026","journal-title":"AJNR Am J Neuroradiol"},{"issue":"8","key":"4410_CR16","first-page":"35","volume":"101","author":"J Nash","year":"2002","unstructured":"Nash J, Cheng JS, Meyer GA, Remler BF (2002) Chiari type I malformation: overview of diagnosis and treatment. WMJ 101(8):35\u201340","journal-title":"WMJ"},{"issue":"2","key":"4410_CR17","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1007\/BF00593966","volume":"35","author":"LJ Stovner","year":"1993","unstructured":"Stovner LJ, Bergan U, Nilsen G, Sjaastad O (1993) Posterior cranial fossa dimensions in the Chiari I malformation: relation to pathogenesis and clinical presentation. Neuroradiology 35(2):113\u2013118","journal-title":"Neuroradiology"},{"issue":"2","key":"4410_CR18","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1007\/s007010200020","volume":"144","author":"F Karagoz","year":"2002","unstructured":"Karagoz F, Izgi N, Kapijcijoglu SS (2002) Morphometric measurements of the cranium in patients with Chiari type I malformation and comparison with the normal population. Acta Neurochir (Wien) 144(2):165\u2013171 (discussion 171)","journal-title":"Acta Neurochir (Wien)"},{"issue":"2","key":"4410_CR19","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1186\/1743-8454-2-11","volume":"18","author":"RF Sekula Jr","year":"2005","unstructured":"Sekula RF Jr, Jannetta PJ, Casey KF, Marchan EM, Sekula LK, McCrady CS (2005) Dimensions of the posterior fossa in patients symptomatic for Chiari I malformation but without cerebellar tonsillar descent. Cerebrospinal Fluid Res 18(2):11","journal-title":"Cerebrospinal Fluid Res"},{"issue":"2","key":"4410_CR20","doi-asserted-by":"crossref","first-page":"291","DOI":"10.3171\/jns.2003.99.2.0291","volume":"99","author":"RS Tubbs","year":"2003","unstructured":"Tubbs RS, McGirt MJ, Oakes WJ (2003) Surgical experience in 130 pediatric patients with Chiari I malformations. J Neurosurg 99(2):291\u2013296","journal-title":"J Neurosurg"},{"issue":"5","key":"4410_CR21","doi-asserted-by":"crossref","first-page":"405","DOI":"10.3340\/jkns.2013.54.5.405","volume":"54","author":"HS Hwang","year":"2013","unstructured":"Hwang HS, Moon JG, Kim CH, Oh SM, Song JH, Jeong JH (2013) The comparative morphometric study of the posterior cranial fossa : what is effective approaches to the treatment of Chiari malformation type 1. J Korean Neurosurg Soc 54(5):405\u2013410","journal-title":"J Korean Neurosurg Soc"},{"issue":"1","key":"4410_CR22","doi-asserted-by":"crossref","first-page":"p155","DOI":"10.1007\/s00586-014-3680-5","volume":"24","author":"D Xie","year":"2015","unstructured":"Xie D, Qiu Y, Sha S et al (2015) Syrinx resolution is correlated with the upward shifting of cerebellar tonsil following posterior fossa decompression in pediatric patients with Chiari malformation type I. Eur Spine J 24(1):p155\u2013p161","journal-title":"Eur Spine J"},{"issue":"10","key":"4410_CR23","doi-asserted-by":"crossref","first-page":"1837","DOI":"10.3174\/ajnr.A2268","volume":"31","author":"KD Krueger","year":"2010","unstructured":"Krueger KD, Haughton VM, Hetzel S (2010) Peak CSF velocities in patients with symptomatic and asymptomatic Chiari I malformation. AJNR Am J Neuroradiol 31(10):1837\u20131841","journal-title":"AJNR Am J Neuroradiol"},{"issue":"3","key":"4410_CR24","doi-asserted-by":"crossref","first-page":"E3","DOI":"10.3171\/foc.2000.8.3.3","volume":"8","author":"G Pinna","year":"2000","unstructured":"Pinna G, Alessandrini F, Alfieri A, Rossi M, Bricolo A (2000) Cerebrospinal fluid flow dynamics study in Chiari I malformation: implications for syrinx formation. Neurosurg Focus 8(3):E3","journal-title":"Neurosurg Focus"},{"issue":"9","key":"4410_CR25","doi-asserted-by":"crossref","first-page":"1860","DOI":"10.1007\/s00330-012-2457-7","volume":"22","author":"AC Bunck","year":"2012","unstructured":"Bunck AC, Kroeger JR, Juettner A, Brentrup A et al (2012) Magnetic resonance 4D flow analysis of cerebrospinal fluid dynamics in Chiari I malformation with and without syrinx. Eur Radiol 22(9):1860\u20131870","journal-title":"Eur Radiol"},{"issue":"1","key":"4410_CR26","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1148\/radiol.2321030666","volume":"232","author":"MF Quigley","year":"2004","unstructured":"Quigley MF, Iskandar B, Quigley ME, Nicosia M, Haughton V (2004) Cerebrospinal fluid flow in foramen magnum: temporal and spatial patterns at MR imaging in volunteers and in patients with Chiari I malformation. Radiology 232(1):229\u2013236","journal-title":"Radiology"},{"issue":"4","key":"4410_CR27","doi-asserted-by":"crossref","first-page":"707","DOI":"10.1007\/s00701-013-1958-8","volume":"156","author":"CS Wang","year":"2014","unstructured":"Wang CS, Wang X, Fu CH, Wei LQ, Zhou DQ, Lin JK (2014) Analysis of cerebrospinal fluid flow dynamics and morphology in Chiari I malformation with cine phase-contrast magnetic resonance imaging. Acta Neurochir (Wien) 156(4):707\u2013713","journal-title":"Acta Neurochir (Wien)"},{"issue":"10","key":"4410_CR28","doi-asserted-by":"crossref","first-page":"e75335","DOI":"10.1371\/journal.pone.0075335","volume":"8","author":"BA Martin","year":"2013","unstructured":"Martin BA, Kalata W, Shaffer N, Fischer P, Luciano M, Loth F (2013) Hydrodynamic and longitudinal impedance analysis of cerebrospinal fluid dynamics at the craniovertebral junction in type I Chiari malformation. PLoS One 8(10):e75335","journal-title":"PLoS One"},{"issue":"12","key":"4410_CR29","doi-asserted-by":"crossref","first-page":"e52284","DOI":"10.1371\/journal.pone.0052284","volume":"7","author":"TI Yiallourou","year":"2012","unstructured":"Yiallourou TI, Kroger JR, Stergiopulos N, Maintz D, Martin BA, Bunck AC (2012) Comparison of 4D phase-contrast MRI flow measurements to computational fluid dynamics simulations of cerebrospinal fluid motion in the cervical spine. PLoS One 7(12):e52284","journal-title":"PLoS One"},{"issue":"5","key":"4410_CR30","doi-asserted-by":"crossref","first-page":"1135","DOI":"10.3171\/2013.2.JNS12759","volume":"118","author":"EC Clarke","year":"2013","unstructured":"Clarke EC, Stoodley MA, Bilston LE (2013) Changes in temporal flow characteristics of CSF in Chiari malformation Type I with and without syrinx: implications for theory of syrinx development. J Neurosurg 118(5):1135\u20131140","journal-title":"J Neurosurg"},{"issue":"5","key":"4410_CR31","doi-asserted-by":"crossref","first-page":"1050","DOI":"10.1097\/00006123-200105000-00016","volume":"48","author":"RS Tubbs","year":"2001","unstructured":"Tubbs RS, Elton S, Grabb P, Dockery SE, Bartolucci AA, Oakes WJ (2001) Analysis of the posterior fossa in children with the Chiari 0 malformation. Neurosurgery 48(5):1050\u20131054 (discussion 1054-1055)","journal-title":"Neurosurgery"},{"issue":"3","key":"4410_CR32","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1016\/j.surneu.2005.02.021","volume":"64","author":"S Aydin","year":"2005","unstructured":"Aydin S, Hanimoglu H, Tanriverdi T, Yentur E, Kaynar MY (2005) Chiari type I malformations in adults: a morphometric analysis of the posterior cranial fossa. Surg Neurol 64(3):237\u2013241 (discussion 241)","journal-title":"Surg Neurol"},{"issue":"3","key":"4410_CR33","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1007\/s00381-007-0432-4","volume":"24","author":"T Trigylidas","year":"2008","unstructured":"Trigylidas T, Baronia B, Vassilyadi M, Ventureyra EC (2008) Posterior fossa dimension and volume estimates in pediatric patients with Chiari I malformations.Child\u2019s nervous system: ChNS Off J Int Soc Pediatr Neurosurg 24(3):329\u2013336","journal-title":"ChNS Off J Int Soc Pediatr Neurosurg"},{"issue":"5","key":"4410_CR34","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1016\/j.clineuro.2010.12.020","volume":"113","author":"A Dagtekin","year":"2011","unstructured":"Dagtekin A, Avci E, Kara E, Uzmansel D et al (2011) Posterior cranial fossa morphometry in symptomatic adult Chiari I malformation patients: comparative clinical and anatomical study. Clin Neurol Neurosurg 113(5):399\u2013403","journal-title":"Clin Neurol Neurosurg"},{"issue":"3","key":"4410_CR35","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1111\/jon.12007","volume":"24","author":"A Urbizu","year":"2013","unstructured":"Urbizu A, Poca MA, Vidal X, Rovira A, Sahuquillo J, Macaya A (2013) MRI-based morphometric analysis of posterior cranial fossa in the diagnosis of chiari malformation type I. J Neuroimaging 24(3):250\u2013256","journal-title":"J Neuroimaging"},{"issue":"1","key":"4410_CR36","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/0022-510X(81)90040-X","volume":"50","author":"M Marin-Padilla","year":"1981","unstructured":"Marin-Padilla M, Marin-Padilla TM (1981) Morphogenesis of experimentally induced Arnold-Chiari malformation. J Neurol Sci 50(1):29\u201355","journal-title":"J Neurol Sci"},{"issue":"2","key":"4410_CR37","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1017\/S0317167100031632","volume":"18","author":"M Marin-Padilla","year":"1991","unstructured":"Marin-Padilla M (1991) Cephalic axial skeletal-neural dysraphic disorders: embryology and pathology. Canadian J Neurol Sci Le J Canadien des Sci Neurologiques 18(2):153\u2013169","journal-title":"Canadian J Neurol Sci Le J Canadien des Sci Neurologiques"},{"issue":"3","key":"4410_CR38","doi-asserted-by":"crossref","first-page":"452","DOI":"10.1017\/S0317167100011860","volume":"38","author":"JA Dufton","year":"2011","unstructured":"Dufton JA, Habeeb SY, Heran MK, Mikulis DJ, Islam O (2011) Posterior fossa measurements in patients with and without Chiari I malformation. Can J Neurol Sci 38(3):452\u2013455","journal-title":"Can J Neurol Sci"},{"issue":"4","key":"4410_CR39","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1007\/s10143-013-0471-0","volume":"36","author":"RV Botelho","year":"2013","unstructured":"Botelho RV, Ferreira ED (2013) Angular craniometry in craniocervical junction malformation. Neurosurg Rev 36(4):603\u2013610 (discussion 610)","journal-title":"Neurosurg Rev"},{"issue":"2 Suppl","key":"4410_CR40","first-page":"169","volume":"101","author":"BJ Iskandar","year":"2004","unstructured":"Iskandar BJ, Quigley M, Haughton VM (2004) Foramen magnum cerebrospinal fluid flow characteristics in children with Chiari I malformation before and after craniocervical decompression. J Neurosurg 101(2 Suppl):169\u2013178","journal-title":"J Neurosurg"}],"container-title":["European Spine Journal"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00586-016-4410-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00586-016-4410-y\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00586-016-4410-y","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,9,3]],"date-time":"2019-09-03T22:40:35Z","timestamp":1567550435000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00586-016-4410-y"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,1,28]]},"references-count":40,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2016,7]]}},"alternative-id":["4410"],"URL":"https:\/\/doi.org\/10.1007\/s00586-016-4410-y","relation":{},"ISSN":["0940-6719","1432-0932"],"issn-type":[{"value":"0940-6719","type":"print"},{"value":"1432-0932","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,1,28]]}}}