{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T20:17:32Z","timestamp":1788380252752,"version":"build-2803163510"},"reference-count":22,"publisher":"Springer Science and Business Media LLC","issue":"7","license":[{"start":{"date-parts":[[2016,2,5]],"date-time":"2016-02-05T00:00:00Z","timestamp":1454630400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"name":"Orthofix, Inc."}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Eur Spine J"],"published-print":{"date-parts":[[2016,7]]},"DOI":"10.1007\/s00586-016-4414-7","type":"journal-article","created":{"date-parts":[[2016,2,5]],"date-time":"2016-02-05T04:52:04Z","timestamp":1454647924000},"page":"2233-2238","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":45,"title":["A prospective clinical and radiographic 12-month outcome study of patients undergoing single-level anterior cervical discectomy and fusion for symptomatic cervical degenerative disc disease utilizing a novel viable allogeneic, cancellous, bone matrix (trinity evolution\u2122) with a comparison to historical controls"],"prefix":"10.1007","volume":"25","author":[{"given":"Jed","family":"Vanichkachorn","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Timothy","family":"Peppers","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dennis","family":"Bullard","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Scott K.","family":"Stanley","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raymond J.","family":"Linovitz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James T.","family":"Ryaby","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2016,2,5]]},"reference":[{"key":"4414_CR1","doi-asserted-by":"crossref","unstructured":"Smith GW, Robinson RA (1958) The treatment of certain cervical-spine disorders by anterior removal of the intervertebral disc and interbody fusion. J Bone Joint Surg Am 40-A:607\u2013624","DOI":"10.2106\/00004623-195840030-00009"},{"key":"4414_CR2","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1016\/S0030-5898(01)00011-6","volume":"33","author":"DG Anderson","year":"2002","unstructured":"Anderson DG, Albert TJ (2002) Bone grafting, implants, and plating options for anterior cervical fusions. Orthop Clin North Am 33:317\u2013328","journal-title":"Orthop Clin North Am"},{"key":"4414_CR3","doi-asserted-by":"crossref","first-page":"398","DOI":"10.1007\/s005860000160","volume":"9","author":"T Floyd","year":"2000","unstructured":"Floyd T, Ohnmeiss D (2000) A meta-analysis of autograft versus allograft in anterior cervical fusion. Euro Spine J Off Publ Euro Spine Soc Euro Spinal Deform Soc Euro Sect Cerv Spine Res Soc 9:398\u2013403","journal-title":"Euro Spine J Off Publ Euro Spine Soc Euro Spinal Deform Soc Euro Sect Cerv Spine Res Soc"},{"key":"4414_CR4","doi-asserted-by":"publisher","first-page":"348","DOI":"10.2174\/1874325001105010348","volume":"5","author":"J Lemcke","year":"2011","unstructured":"Lemcke J, Al-Zain F, Meier U, Suess O (2011) Polyetheretherketone (PEEK) spacers for anterior cervical fusion: a retrospective comparative effectiveness clinical trial. Open Orthop J 5:348\u2013353. doi: 10.2174\/1874325001105010348","journal-title":"Open Orthop J"},{"key":"4414_CR5","doi-asserted-by":"publisher","first-page":"464","DOI":"10.1007\/s00586-009-1161-z","volume":"19","author":"H Lofgren","year":"2010","unstructured":"Lofgren H, Engquist M, Hoffmann P, Sigstedt B, Vavruch L (2010) Clinical and radiological evaluation of Trabecular Metal and the Smith-Robinson technique in anterior cervical fusion for degenerative disease: a prospective, randomized, controlled study with 2-year follow-up. Euro Spine J Off Publ Euro Spine Soc Euro Spinal Deform Soc Euro Sect Cerv Spine Res Soc 19:464\u2013473. doi: 10.1007\/s00586-009-1161-z","journal-title":"Euro Spine J Off Publ Euro Spine Soc Euro Spinal Deform Soc Euro Sect Cerv Spine Res Soc"},{"key":"4414_CR6","doi-asserted-by":"crossref","first-page":"1756","DOI":"10.1097\/01.brs.0000172148.86756.ce","volume":"30","author":"D Samartzis","year":"2005","unstructured":"Samartzis D, Shen FH, Goldberg EJ, An HS (2005) Is autograft the gold standard in achieving radiographic fusion in one-level anterior cervical discectomy and fusion with rigid anterior plate fixation? Spine 30:1756\u20131761","journal-title":"Spine"},{"key":"4414_CR7","doi-asserted-by":"publisher","first-page":"134","DOI":"10.1097\/01.BRS.0000041587.55176.67","volume":"28","author":"JS Silber","year":"2003","unstructured":"Silber JS, Anderson DG, Daffner SD, Brislin BT, Leland JM, Hilibrand AS, Vaccaro AR, Albert TJ (2003) Donor site morbidity after anterior iliac crest bone harvest for single-level anterior cervical discectomy and fusion. Spine 28:134\u2013139. doi: 10.1097\/01.BRS.0000041587.55176.67","journal-title":"Spine"},{"key":"4414_CR8","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1016\/S1529-9430(03)00173-6","volume":"3","author":"D Samartzis","year":"2003","unstructured":"Samartzis D, Shen FH, Matthews DK, Yoon ST, Goldberg EJ, An HS (2003) Comparison of allograft to autograft in multilevel anterior cervical discectomy and fusion with rigid plate fixation. Spine J Off J North Am Spine Soc 3:451\u2013459","journal-title":"Spine J Off J North Am Spine Soc"},{"key":"4414_CR9","doi-asserted-by":"crossref","unstructured":"Cho DY, Liau WR, Lee WY, Liu JT, Chiu CL, Sheu PC (2002) Preliminary experience using a polyetheretherketone (PEEK) cage in the treatment of cervical disc disease. Neurosurgery 51:1343\u20131349 (discussion 1349\u20131350)","DOI":"10.1097\/00006123-200212000-00003"},{"key":"4414_CR10","doi-asserted-by":"publisher","first-page":"115","DOI":"10.1007\/s00701-010-0821-4","volume":"153","author":"J Zhou","year":"2011","unstructured":"Zhou J, Xia Q, Dong J, Li X, Zhou X, Fang T, Lin H (2011) Comparison of stand-alone polyetheretherketone cages and iliac crest autografts for the treatment of cervical degenerative disc diseases. Acta Neurochir (Wien) 153:115\u2013122. doi: 10.1007\/s00701-010-0821-4","journal-title":"Acta Neurochir (Wien)"},{"key":"4414_CR11","doi-asserted-by":"publisher","first-page":"1240","DOI":"10.1016\/j.jocn.2007.05.016","volume":"15","author":"YC Chou","year":"2008","unstructured":"Chou YC, Chen DC, Hsieh WA, Chen WF, Yen PS, Harnod T, Chiou TL, Chang YL, Su CF, Lin SZ, Chen SY (2008) Efficacy of anterior cervical fusion: comparison of titanium cages, polyetheretherketone (PEEK) cages and autogenous bone grafts. J Clin Neurosci Off J Neurosurg Soc Austral 15:1240\u20131245. doi: 10.1016\/j.jocn.2007.05.016","journal-title":"J Clin Neurosci Off J Neurosurg Soc Austral"},{"key":"4414_CR12","doi-asserted-by":"publisher","unstructured":"Mastronardi L, Ducati A, Ferrante L (2006) Anterior cervical fusion with polyetheretherketone (PEEK) cages in the treatment of degenerative disc disease. Preliminary observations in 36 consecutive cases with a minimum 12-month follow-up. Acta Neurochirurg 148:307\u2013312. doi: 10.1007\/s00701-005-0657-5 (discussion 312)","DOI":"10.1007\/s00701-005-0657-5"},{"key":"4414_CR13","doi-asserted-by":"publisher","first-page":"643","DOI":"10.1007\/s00264-007-0378-x","volume":"32","author":"JC Liao","year":"2008","unstructured":"Liao JC, Niu CC, Chen WJ, Chen LH (2008) Polyetheretherketone (PEEK) cage filled with cancellous allograft in anterior cervical discectomy and fusion. Int Orthop 32:643\u2013648. doi: 10.1007\/s00264-007-0378-x","journal-title":"Int Orthop"},{"key":"4414_CR14","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1007\/s10195-011-0169-4","volume":"12","author":"C Faldini","year":"2011","unstructured":"Faldini C, Chehrassan M, Miscione MT, Acri MT, d\u2019Amato M, Pungetti c, Luciani D, Giannini S (2011) Single-level anterior cervical discectomy and interbody fusion using PEEK anatomical cervical cage and allograft bone. J Orthop Traumatol 12:201\u2013205","journal-title":"J Orthop Traumatol"},{"key":"4414_CR15","doi-asserted-by":"publisher","first-page":"238","DOI":"10.1007\/s00586-008-0869-5","volume":"18","author":"K Topuz","year":"2009","unstructured":"Topuz K, Colak A, Kaya S, Simsek H, Kutlay M, Demircan MN, Velioglu M (2009) Two-level contiguous cervical disc disease treated with peek cages packed with demineralized bone matrix: results of 3-year follow-up. Euro Spine J Off Publ Euro Spine Soc Euro Spinal Deform Soc Euro Sect Cerv Spine Res Soc 18:238\u2013243. doi: 10.1007\/s00586-008-0869-5","journal-title":"Euro Spine J Off Publ Euro Spine Soc Euro Spinal Deform Soc Euro Sect Cerv Spine Res Soc"},{"key":"4414_CR16","doi-asserted-by":"publisher","DOI":"10.1016\/j.spinee.2013.08.030","author":"RF Kersten","year":"2013","unstructured":"Kersten RF, van Gaalen SM, de Gast A, Oner FC (2013) Polyetheretherketone (PEEK) cages in cervical applications: a systematic review. Spine J Off J North Am Spine Soc. doi: 10.1016\/j.spinee.2013.08.030","journal-title":"Spine J Off J North Am Spine Soc"},{"key":"4414_CR17","first-page":"s571","volume":"25","author":"AR Vaccaro","year":"2002","unstructured":"Vaccaro AR (2002) The role of the osteoconductive scaffold in synthetic bone graft. Orthopedics 25:s571\u2013s578","journal-title":"Orthopedics"},{"key":"4414_CR18","doi-asserted-by":"publisher","first-page":"140","DOI":"10.1177\/1938640010369638","volume":"3","author":"SM Rush","year":"2010","unstructured":"Rush SM (2010) Trinity Evolution: mesenchymal stem cell allografting in foot and ankle surgery. Foot Ankle Special 3:140\u2013143. doi: 10.1177\/1938640010369638","journal-title":"Foot Ankle Special"},{"key":"4414_CR19","doi-asserted-by":"publisher","first-page":"154","DOI":"10.3171\/2012.10.SPINE12312","volume":"18","author":"SL Parker","year":"2013","unstructured":"Parker SL, Godil SS, Shau DN, Mendenhall SK, McGirt MJ (2013) Assessment of the minimum clinically important difference in pain, disability, and quality of life after anterior cervical discectomy and fusion: clinical article. J Neurosurg Spine 18:154\u2013160. doi: 10.3171\/2012.10.SPINE12312","journal-title":"J Neurosurg Spine"},{"key":"4414_CR20","doi-asserted-by":"publisher","first-page":"2049","DOI":"10.1016\/j.clineuro.2013.07.013","volume":"115","author":"F Chen","year":"2013","unstructured":"Chen F, He W, Mahaney K, Noeller J, Mhanna N, Viljoen S, Torner J, Hitchon P (2013) Alternative grafts in anterior cervical fusion. Clin Neurol Neurosurg 115:2049\u20132055. doi: 10.1016\/j.clineuro.2013.07.013","journal-title":"Clin Neurol Neurosurg"},{"key":"4414_CR21","doi-asserted-by":"publisher","first-page":"1031","DOI":"10.1007\/s00586-014-3696-x","volume":"24","author":"RJ Kroeze","year":"2015","unstructured":"Kroeze RJ, Smit TH, Vergroesen PP, Bank RA, Stoop R, van Rietbergen B, van Royen BJ, Helder MN (2015) Spinal fusion using adipose stem cells seeded on a radiolucent cage filler: a feasibility study of a single surgical procedure in goats. Euro Spine J Off Publ Euro Spine Soc Euro Spinal Deform Soc Euro Sect Cerv Spine Res Soc 24:1031\u20131042. doi: 10.1007\/s00586-014-3696-x","journal-title":"Euro Spine J Off Publ Euro Spine Soc Euro Spinal Deform Soc Euro Sect Cerv Spine Res Soc"},{"key":"4414_CR22","doi-asserted-by":"publisher","first-page":"527","DOI":"10.3171\/2013.7.SPINE13208","volume":"19","author":"M Luszczyk","year":"2013","unstructured":"Luszczyk M, Smith JS, Fischgrund JS, Ludwig SC, Sasso RC, Shaffrey CI, Vaccaro AR (2013) Does smoking have an impact on fusion rate in single-level anterior cervical discectomy and fusion with allograft and rigid plate fixation? Clinical article. J Neurosurg Spine 19:527\u2013531. doi: 10.3171\/2013.7.SPINE13208","journal-title":"J Neurosurg Spine"}],"container-title":["European Spine Journal"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00586-016-4414-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00586-016-4414-7\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00586-016-4414-7","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,9,4]],"date-time":"2019-09-04T04:56:02Z","timestamp":1567572962000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00586-016-4414-7"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,2,5]]},"references-count":22,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2016,7]]}},"alternative-id":["4414"],"URL":"https:\/\/doi.org\/10.1007\/s00586-016-4414-7","relation":{},"ISSN":["0940-6719","1432-0932"],"issn-type":[{"value":"0940-6719","type":"print"},{"value":"1432-0932","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,2,5]]}}}