{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,6]],"date-time":"2026-03-06T03:52:48Z","timestamp":1772769168054,"version":"3.50.1"},"reference-count":45,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2016,12,21]],"date-time":"2016-12-21T00:00:00Z","timestamp":1482278400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Eur Spine J"],"published-print":{"date-parts":[[2017,3]]},"DOI":"10.1007\/s00586-016-4891-8","type":"journal-article","created":{"date-parts":[[2016,12,21]],"date-time":"2016-12-21T08:36:10Z","timestamp":1482309370000},"page":"857-864","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Gender differences after lumbar sequestrectomy: a prospective clinical trial using quantitative sensory testing"],"prefix":"10.1007","volume":"26","author":[{"given":"Anja","family":"Tschugg","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wolfgang N.","family":"L\u00f6scher","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sara","family":"Lener","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matthias","family":"Wildauer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sebastian","family":"Hartmann","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sabrina","family":"Neururer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Claudius","family":"Thom\u00e9","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2016,12,21]]},"reference":[{"key":"4891_CR1","doi-asserted-by":"crossref","first-page":"2451","DOI":"10.1001\/jama.296.20.2451","volume":"296","author":"JN Weinstein","year":"2006","unstructured":"Weinstein JN, Lurie JD, Tosteson TD et al (2006) Surgical vs nonoperative treatment for lumbar disk herniation: the Spine Patient Outcomes Research Trial (SPORT) observational cohort. JAMA 296:2451\u20132459","journal-title":"JAMA"},{"key":"4891_CR2","doi-asserted-by":"crossref","first-page":"271","DOI":"10.3171\/spi.2005.2.3.0271","volume":"2","author":"C Thom\u00e9","year":"2005","unstructured":"Thom\u00e9 C, Barth M, Scharf J, Schmiedek P (2005) Outcome after lumbar sequestrectomy compared with microdiscectomy: a prospective randomized study. J Neurosurg Spine 2:271\u2013278","journal-title":"J Neurosurg Spine"},{"key":"4891_CR3","doi-asserted-by":"crossref","unstructured":"Mannion AF, Porchet F, Kleinst\u00fcck FS, Lattig F, Jeszenszky D, Bartanusz V, Dvorak J, Grob D (2009) The quality of spine surgery from the patient\u2019s perspective: part 2. Minimal clinically important difference for improvement and deterioration as measured with the Core Outcome Measures Index. Eur Spine J 18(Suppl 3):374\u2013379","DOI":"10.1007\/s00586-009-0931-y"},{"key":"4891_CR4","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1080\/17453670810016669","volume":"79","author":"F Str\u00f6mqvist","year":"2008","unstructured":"Str\u00f6mqvist F, Ahmad M, Hildingsson C, J\u00f6nsson B, Str\u00f6mqvist B (2008) Gender differences in lumbar disc herniation surgery. Acta Orthop 79:643\u2013649","journal-title":"Acta Orthop"},{"key":"4891_CR5","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1007\/s00586-001-0354-x","volume":"11","author":"L Samuelsson","year":"2002","unstructured":"Samuelsson L, Lundin A (2002) Thermal quantitative sensory testing in lumbar disc herniation. Eur Spine J 11:71\u201375","journal-title":"Eur Spine J"},{"key":"4891_CR6","first-page":"411","volume":"22","author":"LW Zub","year":"2013","unstructured":"Zub LW, Szymczyk M, Pokryszko-Dragan A, Bili\u0144ska M (2013) Evaluation of pain in patients with lumbar disc surgery using VAS scale and quantitative sensory testing. Adv Clin Exp Med 22:411\u2013419","journal-title":"Adv Clin Exp Med"},{"key":"4891_CR7","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1016\/j.pain.2007.05.004","volume":"135","author":"R Freynhagen","year":"2008","unstructured":"Freynhagen R, Rolke R, Baron R, T\u00f6lle TR, Rutjes AK, Schu S, Treede RD (2008) Pseudoradicular and radicular low-back pain\u2013a disease continuum rather than different entities? Answers from quantitative sensory testing. Pain 135:65\u201374","journal-title":"Pain"},{"key":"4891_CR8","doi-asserted-by":"publisher","DOI":"10.1007\/s00586-015-4052-5","author":"F Str\u00f6mqvist","year":"2015","unstructured":"Str\u00f6mqvist F, Str\u00f6mqvist B, J\u00f6nsson B, Karlsson MK (2015) Gender differences in patients scheduled for lumbar disc herniation surgery: a National Register Study including 15,631 operations. Eur Spine J. doi: 10.1007\/s00586-015-4052-5","journal-title":"Eur Spine J"},{"key":"4891_CR9","doi-asserted-by":"publisher","DOI":"10.1007\/s00586-015-4149-x","author":"F Str\u00f6mqvist","year":"2015","unstructured":"Str\u00f6mqvist F, Str\u00f6mqvist B, J\u00f6nsson B, Gerdhem P, Karlsson MK (2015) Lumbar disc herniation surgery in children: outcome and gender differences. Eur Spine J. doi: 10.1007\/s00586-015-4149-x","journal-title":"Eur Spine J"},{"key":"4891_CR10","first-page":"E715","volume":"16","author":"HJ Kim","year":"2013","unstructured":"Kim HJ, Suh BG, Lee DB, Park JY, Kang KT, Chang BS, Lee CK, Yeom JS (2013) Gender difference of symptom severity in lumbar spinal stenosis: role of pain sensitivity. Pain Physician 16:E715\u2013E723","journal-title":"Pain Physician"},{"key":"4891_CR11","doi-asserted-by":"crossref","first-page":"771","DOI":"10.1089\/jwh.2014.5108","volume":"24","author":"A Tschugg","year":"2015","unstructured":"Tschugg A, L\u00f6scher WN, Hartmann S, Neururer S, Wildauer M, Thom\u00e9 C (2015) Gender influences radicular pain perception in patients with lumbar disc herniation. J Womens Health (Larchmt) 24:771\u2013776","journal-title":"J Womens Health (Larchmt)"},{"key":"4891_CR12","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1007\/s00586-015-4062-3","volume":"25","author":"L Pochon","year":"2016","unstructured":"Pochon L, Kleinst\u00fcck FS, Porchet F, Mannion AF (2016) Influence of gender on patient-oriented outcomes in spine surgery. Eur Spine J 25:235\u2013246","journal-title":"Eur Spine J"},{"key":"4891_CR13","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1016\/S0149-7634(00)00017-8","volume":"24","author":"RB Fillingim","year":"2000","unstructured":"Fillingim RB, Ness TJ (2000) Sex-related hormonal influences on pain and analgesic responses. Neurosci Biobehav Rev 24:485\u2013501","journal-title":"Neurosci Biobehav Rev"},{"key":"4891_CR14","doi-asserted-by":"crossref","first-page":"1873","DOI":"10.1097\/00007632-200109010-00011","volume":"26","author":"CW Pfirrmann","year":"2001","unstructured":"Pfirrmann CW, Metzdorf A, Zanetti M, Hodler J, Boos N (2001) Magnetic resonance classification of lumbar intervertebral disc degeneration. Spine (Phila Pa 1976) 26:1873\u20131878","journal-title":"Spine (Phila Pa 1976)"},{"key":"4891_CR15","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1148\/radiology.166.1.3336678","volume":"166","author":"MT Modic","year":"1988","unstructured":"Modic MT, Steinberg PM, Ross JS, Masaryk TJ, Carter JR (1988) Degenerative disk disease: assessment of changes in vertebral body marrow with MR imaging. Radiology 166:193\u2013199","journal-title":"Radiology"},{"issue":"Suppl 11","key":"4891_CR16","doi-asserted-by":"crossref","first-page":"S454","DOI":"10.1002\/acr.20556","volume":"63","author":"KL Smarr","year":"2011","unstructured":"Smarr KL, Keefer AL (2011) Measures of depression and depressive symptoms: Beck Depression Inventory-II (BDI-II), Center for Epidemiologic Studies Depression Scale (CES-D), Geriatric Depression Scale (GDS), Hospital Anxiety and Depression Scale (HADS), and Patient Health Questionnaire-9 (PHQ-9). Arthritis Care Res (Hoboken) 63(Suppl 11):S454\u2013S466","journal-title":"Arthritis Care Res (Hoboken)"},{"key":"4891_CR17","doi-asserted-by":"crossref","first-page":"1911","DOI":"10.1185\/030079906X132488","volume":"22","author":"R Freynhagen","year":"2006","unstructured":"Freynhagen R, Baron R, Gockel U, T\u00f6lle TR (2006) painDETECT: a new screening questionnaire to identify neuropathic components in patients with back pain. Curr Med Res Opin 22:1911\u20131920","journal-title":"Curr Med Res Opin"},{"key":"4891_CR18","first-page":"271","volume":"66","author":"JC Fairbank","year":"1980","unstructured":"Fairbank JC, Couper J, Davies JB, O\u2019Brien JP (1980) The Oswestry low back pain disability questionnaire. Physiotherapy 66:271\u2013273","journal-title":"Physiotherapy"},{"issue":"Suppl 3","key":"4891_CR19","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1007\/s00586-009-0942-8","volume":"18","author":"AF Mannion","year":"2009","unstructured":"Mannion AF, Porchet F, Kleinst\u00fcck FS, Lattig F, Jeszenszky D, Bartanusz V, Dvorak J, Grob D (2009) The quality of spine surgery from the patient\u2019s perspective. Part 1: the Core Outcome Measures Index in clinical practice. Eur Spine J 18(Suppl 3):367\u2013373","journal-title":"Eur Spine J"},{"key":"4891_CR20","doi-asserted-by":"crossref","first-page":"873","DOI":"10.1002\/hec.866","volume":"13","author":"J Brazier","year":"2004","unstructured":"Brazier J, Roberts J, Tsuchiya A, Busschbach J (2004) A comparison of the EQ-5D and SF-6D across seven patient groups. Health Econ 13:873\u2013884","journal-title":"Health Econ"},{"key":"4891_CR21","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/j.ejpain.2005.02.003","volume":"10","author":"R Rolke","year":"2006","unstructured":"Rolke R, Magerl W, Campbell KA, Schalber C, Caspari S, Birklein F, Treede -D (2006) Quantitative sensory testing: a comprehensive protocol for clinical trials. Eur J Pain 10:77","journal-title":"Eur J Pain"},{"key":"4891_CR22","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1016\/j.pain.2006.01.041","volume":"123","author":"R Rolke","year":"2006","unstructured":"Rolke R, Baron R, Maier C et al (2006) Quantitative sensory testing in the German Research Network on Neuropathic Pain (DFNS): standardized protocol and reference values. Pain 123:231\u2013243","journal-title":"Pain"},{"key":"4891_CR23","doi-asserted-by":"crossref","first-page":"1639","DOI":"10.1111\/j.1526-4637.2012.01523.x","volume":"13","author":"AM Castro-S\u00e1nchez","year":"2012","unstructured":"Castro-S\u00e1nchez AM, Matar\u00e1n-Pe\u00f1arrocha GA, L\u00f3pez-Rodr\u00edguez MM, Lara-Palomo IC, Arendt-Nielsen L, Fern\u00e1ndez-de-las-Pe\u00f1as C (2012) Gender differences in pain severity, disability, depression, and widespread pressure pain sensitivity in patients with fibromyalgia syndrome without comorbid conditions. Pain Med 13:1639\u20131647","journal-title":"Pain Med"},{"key":"4891_CR24","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1097\/00002508-200103000-00004","volume":"17","author":"GB Rollman","year":"2001","unstructured":"Rollman GB, Lautenbacher S (2001) Sex differences in musculoskeletal pain. Clin J Pain 17:20\u201324","journal-title":"Clin J Pain"},{"key":"4891_CR25","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1016\/S0304-3959(02)00330-5","volume":"101","author":"LS Chesterton","year":"2003","unstructured":"Chesterton LS, Barlas P, Foster NE, Baxter G, Wright CC (2003) Gender differences in pressure pain threshold in healthy humans. Pain 101:259\u2013266","journal-title":"Pain"},{"key":"4891_CR26","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1016\/S0304-3959(97)00199-1","volume":"74","author":"JL Riley","year":"1998","unstructured":"Riley JL, Robinson ME, Wise EA, Myers CD, Fillingim RB (1998) Sex differences in the perception of noxious experimental stimuli: a meta-analysis. Pain 74:181\u2013187","journal-title":"Pain"},{"key":"4891_CR27","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1016\/j.pain.2010.05.002","volume":"150","author":"C Maier","year":"2010","unstructured":"Maier C, Baron R, T\u00f6lle TR et al (2010) Quantitative sensory testing in the German Research Network on Neuropathic Pain (DFNS): somatosensory abnormalities in 1236 patients with different neuropathic pain syndromes. Pain 150:439\u2013450","journal-title":"Pain"},{"key":"4891_CR28","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1007\/s00586-006-0187-8","volume":"16","author":"A H\u00e4kkinen","year":"2007","unstructured":"H\u00e4kkinen A, Kautiainen H, J\u00e4rvenp\u00e4\u00e4 S, Arkela-Kautiainen M, Ylinen J (2007) Changes in the total Oswestry Index and its ten items in females and males pre- and post-surgery for lumbar disc herniation: a 1-year follow-up. Eur Spine J 16:347\u2013352","journal-title":"Eur Spine J"},{"key":"4891_CR29","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1007\/s00586-015-4052-5","volume":"25","author":"F Str\u00f6mqvist","year":"2015","unstructured":"Str\u00f6mqvist F, Str\u00f6mqvist B, J\u00f6nsson B, Karlsson MK (2015) Gender differences in patients scheduled for lumbar disc herniation surgery: a National Register Study including 15,631 operations. Eur Spine J 25:162\u2013167","journal-title":"Eur Spine J"},{"key":"4891_CR30","first-page":"39","volume":"61","author":"J He","year":"2014","unstructured":"He J, Xiong W, Li F, Luo W, Gao S (2014) Depression influences pain and function after cervical disc arthroplasty. J Neurosurg Sci\u00a061:39\u201345","journal-title":"J Neurosurg Sci"},{"key":"4891_CR31","doi-asserted-by":"crossref","first-page":"e0154114","DOI":"10.1371\/journal.pone.0154114","volume":"11","author":"P Azimi","year":"2016","unstructured":"Azimi P, Benzel EC, Montazeri A (2016) Predictive score card in lumbar disc herniation: is it reflective of patient surgical success after discectomy? PLoS One 11:e0154114","journal-title":"PLoS One"},{"key":"4891_CR32","doi-asserted-by":"crossref","first-page":"e0160541","DOI":"10.1371\/journal.pone.0160541","volume":"11","author":"P Azimi","year":"2016","unstructured":"Azimi P, Benzel EC (2016) Cut-off value for pain sensitivity questionnaire in predicting surgical success in patients with lumbar disc herniation. PLoS One 11:e0160541","journal-title":"PLoS One"},{"issue":"41","key":"4891_CR33","first-page":"217","volume":"1992","author":"JW Frymoyer","year":"1992","unstructured":"Frymoyer JW (1992) Lumbar disk disease: epidemiology. Instr Course Lect 1992(41):217\u2013223","journal-title":"Instr Course Lect"},{"key":"4891_CR34","doi-asserted-by":"crossref","first-page":"2245","DOI":"10.1056\/NEJMoa064039","volume":"356","author":"WC Peul","year":"2007","unstructured":"Peul WC, van Houwelingen HC, van den Hout WB, Brand R, Eekhof JA, Tans JT, Thomeer RT, Koes BW, Leiden-The Hague Spine Intervention Prognostic Study Group (2007) Surgery versus prolonged conservative treatment for sciatica. N Engl J Med 356:2245\u20132256","journal-title":"N Engl J Med"},{"key":"4891_CR35","doi-asserted-by":"crossref","first-page":"412","DOI":"10.1542\/peds.2004-2766","volume":"117","author":"AC Diepenmaat","year":"2006","unstructured":"Diepenmaat AC, van der Wal MF, de Vet HC, Hirasing RA (2006) Neck\/shoulder, low back, and arm pain in relation to computer use, physical activity, stress, and depression among Dutch adolescents. Pediatrics 117:412\u2013416","journal-title":"Pediatrics"},{"key":"4891_CR36","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1186\/1471-2474-6-52","volume":"6","author":"N Wedderkopp","year":"2005","unstructured":"Wedderkopp N, Andersen LB, Froberg K, Leboeuf-Yde C (2005) Back pain reporting in young girls appears to be puberty-related. BMC Musculoskelet Disord 6:52","journal-title":"BMC Musculoskelet Disord"},{"key":"4891_CR37","doi-asserted-by":"crossref","first-page":"662","DOI":"10.2106\/JBJS.I.01568","volume":"93","author":"D Samartzis","year":"2011","unstructured":"Samartzis D, Karppinen J, Mok F, Fong DY, Luk KD, Cheung KM (2011) A population-based study of juvenile disc degeneration and its association with overweight and obesity, low back pain, and diminished functional status. J Bone Joint Surg Am 93:662\u2013670","journal-title":"J Bone Joint Surg Am"},{"key":"4891_CR38","doi-asserted-by":"crossref","first-page":"2392","DOI":"10.1002\/art.27523","volume":"62","author":"KM Cheung","year":"2010","unstructured":"Cheung KM, Samartzis D, Karppinen J, Mok FP, Ho DW, Fong DY, Luk KD (2010) Intervertebral disc degeneration: new insights based on \u201cskipped\u201d level disc pathology. Arthritis Rheum 62:2392\u20132400","journal-title":"Arthritis Rheum"},{"key":"4891_CR39","doi-asserted-by":"crossref","first-page":"1625","DOI":"10.1097\/00007632-200007010-00005","volume":"25","author":"MA Adams","year":"2000","unstructured":"Adams MA, Freeman BJ, Morrison HP, Nelson IW, Dolan P (2000) Mechanical initiation of intervertebral disc degeneration. Spine (Phila Pa 1976) 25:1625\u20131636","journal-title":"Spine (Phila Pa 1976)"},{"key":"4891_CR40","doi-asserted-by":"crossref","first-page":"903","DOI":"10.1038\/sj.ijo.0802974","volume":"29","author":"M Liuke","year":"2005","unstructured":"Liuke M, Solovieva S, Lamminen A, Luoma K, Leino-Arjas P, Luukkonen R, Riihim\u00e4ki H (2005) Disc degeneration of the lumbar spine in relation to overweight. Int J Obes (Lond) 29:903\u2013908","journal-title":"Int J Obes (Lond)"},{"issue":"Suppl 2","key":"4891_CR41","first-page":"41","volume":"88","author":"JC Iatridis","year":"2006","unstructured":"Iatridis JC, MacLean JJ, Roughley PJ, Alini M (2006) Effects of mechanical loading on intervertebral disc metabolism in vivo. J Bone Joint Surg Am 88(Suppl 2):41\u201346","journal-title":"J Bone Joint Surg Am"},{"key":"4891_CR42","doi-asserted-by":"crossref","first-page":"476","DOI":"10.1016\/j.whi.2015.05.005","volume":"25","author":"LB Chou","year":"2015","unstructured":"Chou LB, Lerner LB, Harris AH, Brandon AJ, Girod S, Butler LM (2015) Cancer prevalence among a cross-sectional survey of female orthopedic, urology, and plastic surgeons in the United States. Womens Health Issues 25:476\u2013481","journal-title":"Womens Health Issues"},{"key":"4891_CR43","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1038\/ejcn.2009.101","volume":"64","author":"J Stevens","year":"2010","unstructured":"Stevens J, Katz EG, Huxley RR (2010) Associations between gender, age and waist circumference. Eur J Clin Nutr 64:6\u201315","journal-title":"Eur J Clin Nutr"},{"key":"4891_CR44","doi-asserted-by":"crossref","first-page":"e56244","DOI":"10.1371\/journal.pone.0056244","volume":"8","author":"J Takatalo","year":"2013","unstructured":"Takatalo J, Karppinen J, Taimela S et al (2013) Association of abdominal obesity with lumbar disc degeneration\u2014a magnetic resonance imaging study. PLoS ONE 8:e56244","journal-title":"PLoS ONE"},{"key":"4891_CR45","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1016\/S0304-3959(98)00258-9","volume":"81","author":"JL Riley","year":"1999","unstructured":"Riley JL, Robinson ME, Wise EA, Price DD (1999) A meta-analytic review of pain perception across the menstrual cycle. Pain 81:225\u2013235","journal-title":"Pain"}],"container-title":["European Spine Journal"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00586-016-4891-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00586-016-4891-8\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00586-016-4891-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,6,25]],"date-time":"2017-06-25T02:27:53Z","timestamp":1498357673000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00586-016-4891-8"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,12,21]]},"references-count":45,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2017,3]]}},"alternative-id":["4891"],"URL":"https:\/\/doi.org\/10.1007\/s00586-016-4891-8","relation":{},"ISSN":["0940-6719","1432-0932"],"issn-type":[{"value":"0940-6719","type":"print"},{"value":"1432-0932","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,12,21]]}}}