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Age, initial curve magnitude and other parameters define whether a scoliotic deformity will progress or not. Still,\u00a0their interactions and amounts of individual contribution are not fully elaborated and were the aim of this systematic review.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A systematic literature search was conducted in the common databases using MESH terms, searching for predictive factors of curve progression in adolescent idiopathic scoliosis\u00a0(\u201cadolescent idiopathic scoliosis\u201d OR \u201cais\u201d OR \u201cidiopathic scoliosis\u201d) AND (\u201cpredictive factors\u201d OR \u201cprogression\u201d OR \u201ccurve progression\u201d OR \u201cprediction\u201d OR \u201cprognosis\u201d).\u00a0The identified and analysed factors of each study were rated to design a top five scale of the most relevant factors.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Twenty-eight investigations with 8255\u00a0patients were identified by literature search.\u00a0Patient-specific risk factors for curve progression from initial curve were age (at diagnosis\u2009&lt;\u200913\u00a0years), family history,\u00a0bone mineral status (&lt;\u2009110\u00a0mg\/cm\n                      <jats:sup>3<\/jats:sup>\n                      \u00a0in quantitative CT) and\u00a0height velocity (7\u20138\u00a0cm\/year, peak 11.6\u2009\u00b1\u20091.4\u00a0years). Relevant radiological criteria indicating\u00a0curve progression included skeletal maturity, marked by Risser stages (Risser\u2009&lt;\u20091) or Sanders Maturity Scale (SMS\u2009&lt;\u20095), the initial extent of the Cobb angle (&gt;\u200925\u00b0 progression) and curve location (thoracic single or double curve).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion<\/jats:title>\n                    <jats:p>This systematic review summarised the current state of knowledge as the basis for creation of patient-specific algorithms regarding a risk calculation for a progressive scoliotic deformity. Curve magnitude is the most relevant predictive factor, followed by status of skeletal maturity and curve location.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s00586-021-06817-0","type":"journal-article","created":{"date-parts":[[2021,3,26]],"date-time":"2021-03-26T14:02:27Z","timestamp":1616767347000},"page":"1813-1822","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":80,"title":["Scoliosis and Prognosis\u2014a systematic review regarding patient-specific and radiological predictive factors for curve progression"],"prefix":"10.1007","volume":"30","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1176-0166","authenticated-orcid":false,"given":"Maximilian","family":"Lenz","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stavros","family":"Oikonomidis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arne","family":"Harland","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philipp","family":"F\u00fcrnstahl","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mazda","family":"Farshad","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jan","family":"Bredow","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peer","family":"Eysel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Max Joseph","family":"Scheyerer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2021,3,26]]},"reference":[{"issue":"1","key":"6817_CR1","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1007\/s11832-012-0457-4","volume":"7","author":"MR Konieczny","year":"2013","unstructured":"Konieczny MR, Senyurt H, Krauspe R (2013) Epidemiology of adolescent idiopathic scoliosis. 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