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Karola Marcinkowskiego w Poznaniu","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100010438","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Eur Spine J"],"published-print":{"date-parts":[[2023,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Purpose<\/jats:title>\n                <jats:p>Neutrophile-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) are the inflammatory biomarkers of the stress response. In this study, we aimed to evaluate the effects of erector spinae plane block (ESPB) on posterior lumbar decompression and stabilization by comparing NLR, PLR, postoperative pain, opioid consumption, and functional recovery between sham block and ESPB.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methods<\/jats:title>\n                <jats:p>This was a prospective, double-blinded, randomized controlled trial in a tertiary referral hospital. Sixty patients were randomized into two equal groups, each receiving either a sham block or ESPB. The primary outcome was the NLR and PLR 12\u00a0h and 24\u00a0h after lumbar posterior decompression and stabilization. The secondary outcomes were total opioid consumption and pain score 24\u00a0h postoperatively. Also, functional recovery determined by getting out of bed, verticalization, and walking by the balcony were reviewed as secondary outcomes.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>Significant differences existed between the sham block and ESPB group in NLR (29.08\u2009\u00b1\u200912.29 vs. 16.97\u2009\u00b1\u200910.38; p\u2009&lt;\u20090.0001) and PLR (556.77\u2009\u00b1\u2009110.32 vs. 346.43\u2009\u00b1\u2009117.34; <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.0001) 12\u00a0h after surgery. Also, there was a significant difference in NLR (<jats:italic>p<\/jats:italic>\u2009=\u20090.0466) and PLR (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.0001) 24\u00a0h after surgery. In addition, there was a substantial difference in pain score, total opioid consumption, and functional recovery.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>ESPB performance during spinal surgery lowers NRL and PLR ratios 12\u00a0h and 24\u00a0h after surgery. In addition, ESPB provides better analgesia and improves functional recovery compared to sham block following posterior lumbar decompression and stabilization.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1007\/s00586-023-07913-z","type":"journal-article","created":{"date-parts":[[2023,9,5]],"date-time":"2023-09-05T11:02:25Z","timestamp":1693911745000},"page":"4192-4199","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":28,"title":["The neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) levels following erector spinae plane block (ESPB) in posterior lumbar decompression: a randomized, controlled trial"],"prefix":"10.1007","volume":"32","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9067-0969","authenticated-orcid":false,"given":"Ma\u0142gorzata","family":"Domagalska","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bahadir","family":"Ciftsi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Piotr","family":"Janusz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tomasz","family":"Reysner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jerzy","family":"Kolasinski","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katarzyna","family":"Wieczorowska - Tobis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Grzegorz","family":"Kowalski","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2023,9,5]]},"reference":[{"issue":"4","key":"7913_CR1","doi-asserted-by":"publisher","first-page":"695","DOI":"10.1016\/j.ajem.2019.06.001","volume":"38","author":"R Daoust","year":"2020","unstructured":"Daoust R, Paquet J, Cournoyer A, Piette \u00c9, Morris J, Lessard J et al (2020) Side effects from opioids used for acute pain after emergency department discharge. 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