{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,13]],"date-time":"2026-06-13T14:55:55Z","timestamp":1781362555558,"version":"3.54.1"},"reference-count":24,"publisher":"Springer Science and Business Media LLC","license":[{"start":{"date-parts":[[2026,6,13]],"date-time":"2026-06-13T00:00:00Z","timestamp":1781308800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2026,6,13]],"date-time":"2026-06-13T00:00:00Z","timestamp":1781308800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"crossref","award":["82102638"],"award-info":[{"award-number":["82102638"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"crossref","award":["82171927"],"award-info":[{"award-number":["82171927"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Eur Spine J"],"DOI":"10.1007\/s00586-026-10048-6","type":"journal-article","created":{"date-parts":[[2026,6,13]],"date-time":"2026-06-13T14:52:22Z","timestamp":1781362342000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Prediction of pedicle screw fixation strength under craniocaudal cyclic load: comparison of various models trained on quantitative CT based finite element analysis"],"prefix":"10.1007","author":[{"given":"Chenyu","family":"Jiang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiahao","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hanqiang","family":"Ouyang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daole","family":"Hu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yating","family":"Hao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuyu","family":"Dong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guoguo","family":"Tang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zimu","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yifan","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manling","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tong","family":"Zuo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ning","family":"Lang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liang","family":"Jiang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhen","family":"Qian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huishu","family":"Yuan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,6,13]]},"reference":[{"key":"10048_CR1","doi-asserted-by":"publisher","first-page":"347","DOI":"10.1227\/NEU.0000000000000852","volume":"77","author":"M Bydon","year":"2015","unstructured":"Bydon M, Abt NB, De la Garza-Ramos R et al (2015) Impact of age on short-term outcomes after lumbar fusion: an analysis of 1395 patients stratified by decade cohorts. Neurosurgery 77:347\u2013354","journal-title":"Neurosurgery"},{"issue":"5","key":"10048_CR2","doi-asserted-by":"publisher","first-page":"1005","DOI":"10.1007\/s00586-015-3768-6","volume":"24","author":"F Galbusera","year":"2015","unstructured":"Galbusera F, Volkheimer D, Reitmaier S, Berger-Roscher N, Kienle A, Wilke HJ (2015) Pedicle screw loosening: a clinically relevant complication? Eur Spine J 24(5):1005\u20131016","journal-title":"Eur Spine J"},{"issue":"1","key":"10048_CR3","doi-asserted-by":"publisher","first-page":"54","DOI":"10.1016\/j.spinee.2010.09.024","volume":"11","author":"KE Ponnusamy","year":"2011","unstructured":"Ponnusamy KE, Iyer S, Gupta G, Khanna AJ (2011) Instrumentation of the osteoporotic spine: biomechanical and clinical considerations. Spine J 11(1):54\u201363","journal-title":"Spine J"},{"issue":"5","key":"10048_CR4","doi-asserted-by":"publisher","first-page":"455","DOI":"10.1007\/s00068-013-0310-6","volume":"39","author":"A El Saman","year":"2013","unstructured":"El Saman A, Meier S, Sander A, Kelm A, Marzi I, Laurer H (2013) Reduced loosening rate and loss of correction following posterior stabilization with or without PMMA augmentation of pedicle screws in vertebral fractures in the elderly. Eur J Trauma Emerg Surg 39(5):455\u2013460","journal-title":"Eur J Trauma Emerg Surg"},{"issue":"4","key":"10048_CR5","doi-asserted-by":"publisher","first-page":"1064","DOI":"10.1177\/21925682211017477","volume":"13","author":"L Yuan","year":"2023","unstructured":"Yuan L, Zhang X, Zeng Y, Chen Z, Li W, Incidence (2023) Risk, and Outcome of Pedicle Screw Loosening in Degenerative Lumbar Scoliosis Patients Undergoing Long-Segment Fusion. Global Spine J 13(4):1064\u20131071","journal-title":"Global Spine J"},{"issue":"9","key":"10048_CR6","doi-asserted-by":"publisher","first-page":"E473","DOI":"10.1097\/BSD.0000000000000703","volume":"31","author":"K Ishikawa","year":"2018","unstructured":"Ishikawa K, Toyone T, Shirahata T et al (2018) A Novel Method for the Prediction of the Pedicle Screw Stability: Regional Bone Mineral Density Around the Screw. Clin Spine Surg 31(9):E473\u2013E480","journal-title":"Clin Spine Surg"},{"issue":"2","key":"10048_CR7","doi-asserted-by":"publisher","first-page":"E10","DOI":"10.3171\/2020.5.FOCUS20249","volume":"49","author":"F Xu","year":"2020","unstructured":"Xu F, Zou D, Li WS et al (2020) Hounsfield units of the vertebral body and pedicle as predictors of pedicle screw loosening after degenerative lumbar spine surgery. Neurosurg Focus 49(2):E10","journal-title":"Neurosurg Focus"},{"issue":"6","key":"10048_CR8","doi-asserted-by":"publisher","first-page":"1714","DOI":"10.1007\/s00330-014-3529-7","volume":"25","author":"JL Wichmann","year":"2015","unstructured":"Wichmann JL, Booz C, Wesarg S et al (2015) Quantitative dual-energy CT for phantomless evaluation of cancellous bone mineral density of the vertebral pedicle: correlation with pedicle screw pull-out strength. Eur Radiol 25(6):1714\u20131720","journal-title":"Eur Radiol"},{"issue":"4","key":"10048_CR9","doi-asserted-by":"publisher","first-page":"E10","DOI":"10.3171\/2022.1.FOCUS21721","volume":"52","author":"C Ma","year":"2022","unstructured":"Ma C, Zou D, Qi H et al (2022) A novel surgical planning system using an AI model to optimize planning of pedicle screw trajectories with highest bone mineral density and strongest pull-out force. Neurosurg Focus 52(4):E10","journal-title":"Neurosurg Focus"},{"issue":"4","key":"10048_CR10","doi-asserted-by":"publisher","first-page":"464","DOI":"10.1080\/10255842.2021.1959558","volume":"25","author":"S Caprara","year":"2022","unstructured":"Caprara S, Fasser MR, Spirig JM et al (2022) Bone density optimized pedicle screw instrumentation improves screw pull-out force in lumbar vertebrae. Comput Methods Biomech Biomed Engin 25(4):464\u2013474","journal-title":"Comput Methods Biomech Biomed Engin"},{"issue":"5","key":"10048_CR11","doi-asserted-by":"publisher","first-page":"366","DOI":"10.1016\/j.spinee.2008.07.008","volume":"9","author":"BG Santoni","year":"2009","unstructured":"Santoni BG, Hynes RA, McGilvray KC et al (2009) Cortical bone trajectory for lumbar pedicle screws. Spine J 9(5):366\u2013373","journal-title":"Spine J"},{"issue":"1","key":"10048_CR12","doi-asserted-by":"publisher","first-page":"454","DOI":"10.1038\/s41598-023-27433-6","volume":"13","author":"MK Hsieh","year":"2023","unstructured":"Hsieh MK, Lee DM, Li YD et al (2023) Biomechanical evaluation of position and bicortical fixation of anterior lateral vertebral screws in a porcine model. Sci Rep 13(1):454","journal-title":"Sci Rep"},{"issue":"4","key":"10048_CR13","doi-asserted-by":"publisher","first-page":"155","DOI":"10.1080\/10255842.2019.1709173","volume":"23","author":"J Widmer","year":"2020","unstructured":"Widmer J, Fasser MR, Croci E, Spirig J, Snedeker JG, Farshad M (2020) Individualized prediction of pedicle screw FS-CLwith a finite element model. Comput Methods Biomech Biomed Engin 23(4):155\u2013167","journal-title":"Comput Methods Biomech Biomed Engin"},{"issue":"3","key":"10048_CR14","doi-asserted-by":"publisher","first-page":"E226","DOI":"10.1097\/BSD.0000000000000151","volume":"30","author":"RJ Bianco","year":"2017","unstructured":"Bianco RJ, Arnoux PJ, Wagnac E, Mac-Thiong JM, Aubin C\u00c9 (2017) Minimizing Pedicle Screw Pullout Risks: A Detailed Biomechanical Analysis of Screw Design and Placement. Clin Spine Surg 30(3):E226\u2013E232","journal-title":"Clin Spine Surg"},{"key":"10048_CR15","doi-asserted-by":"publisher","first-page":"104359","DOI":"10.1016\/j.jmbbm.2021.104359","volume":"116","author":"L Molinari","year":"2021","unstructured":"Molinari L, Falcinelli C, Gizzi A, Di Martino A (2021) Effect of pedicle screw angles on the fracture risk of the human vertebra: A patient-specific computational model. J Mech Behav Biomed Mater 116:104359","journal-title":"J Mech Behav Biomed Mater"},{"issue":"10","key":"10048_CR16","doi-asserted-by":"publisher","first-page":"2639","DOI":"10.1007\/s00586-022-07187-x","volume":"31","author":"MR Fasser","year":"2022","unstructured":"Fasser MR, Gerber G, Passaplan C et al (2022) Computational model predicts risk of spinal screw loosening in patients. Eur Spine J 31(10):2639\u20132649","journal-title":"Eur Spine J"},{"key":"10048_CR17","doi-asserted-by":"publisher","first-page":"107625","DOI":"10.1016\/j.cmpb.2023.107625","volume":"238","author":"F Song","year":"2023","unstructured":"Song F, Liu Y, Fu R et al (2023) Craniocaudal toggling increases the risk of screw loosening in osteoporotic vertebrae. Comput Methods Programs Biomed 238:107625","journal-title":"Comput Methods Programs Biomed"},{"issue":"1","key":"10048_CR18","doi-asserted-by":"publisher","first-page":"41","DOI":"10.1016\/S0021-9290(96)00103-0","volume":"30","author":"A Rohlmann","year":"1997","unstructured":"Rohlmann A, Bergmann G, Graichen F (1997) Loads on an internal spinal fixation device during walking. J Biomech 30(1):41\u201347","journal-title":"J Biomech"},{"issue":"11","key":"10048_CR19","doi-asserted-by":"publisher","first-page":"2271","DOI":"10.1007\/s00198-019-05117-0","volume":"30","author":"M Zhang","year":"2019","unstructured":"Zhang M, Gong H, Zhang K, Zhang M (2019) Prediction of lumbar vertebral strength of elderly men based on quantitative computed tomography images using machine learning. Osteoporos Int 30(11):2271\u20132282","journal-title":"Osteoporos Int"},{"issue":"1","key":"10048_CR20","doi-asserted-by":"publisher","first-page":"170","DOI":"10.1002\/jor.25334","volume":"41","author":"M Zhang","year":"2023","unstructured":"Zhang M, Gong H, Zhang M (2023) Prediction of femoral strength of elderly men based on quantitative computed tomography images using machine learning. J Orthop Res 41(1):170\u2013182","journal-title":"J Orthop Res"},{"issue":"6","key":"10048_CR21","doi-asserted-by":"publisher","first-page":"876","DOI":"10.1002\/jbmr.4805","volume":"38","author":"Z Yosibash","year":"2023","unstructured":"Yosibash Z, Trabelsi N, Buchnik I et al (2023) Hip Fracture Risk Assessment in Elderly and Diabetic Patients: Combining Autonomous Finite Element Analysis and Machine Learning. J Bone Min Res 38(6):876\u2013886","journal-title":"J Bone Min Res"},{"key":"10048_CR22","doi-asserted-by":"publisher","first-page":"897","DOI":"10.1016\/S0021-9290(03)00071-X","volume":"36","author":"EF Morgan","year":"2003","unstructured":"Morgan EF, Bayraktar HH, Keaveny TM (2003) Trabecular bone modulus-density relationships depend on anatomic site. J Biomech 36:897\u2013904","journal-title":"J Biomech"},{"key":"10048_CR23","doi-asserted-by":"publisher","first-page":"569","DOI":"10.1016\/S0021-9290(01)00011-2","volume":"34","author":"EF Morgan","year":"2001","unstructured":"Morgan EF, Keaveny TM (2001) Dependence of yield strain of human trabecular bone on anatomic site. J Biomech 34:569\u2013577","journal-title":"J Biomech"},{"key":"10048_CR24","unstructured":"Chen S, Ma K, Zheng Y (2019) Med3d: Transfer learning for 3d medical image analysis[EB\/OL]. arXiv preprint arXiv:1904.00625. https:\/\/arxiv.org\/abs\/1904.00625"}],"container-title":["European Spine Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00586-026-10048-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00586-026-10048-6","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00586-026-10048-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,13]],"date-time":"2026-06-13T14:52:25Z","timestamp":1781362345000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00586-026-10048-6"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,6,13]]},"references-count":24,"alternative-id":["10048"],"URL":"https:\/\/doi.org\/10.1007\/s00586-026-10048-6","relation":{},"ISSN":["0940-6719","1432-0932"],"issn-type":[{"value":"0940-6719","type":"print"},{"value":"1432-0932","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,6,13]]},"assertion":[{"value":"10 March 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"30 April 2026","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"23 May 2026","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"13 June 2026","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}]}}