{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T13:56:16Z","timestamp":1790776576415,"version":"4.1.0"},"reference-count":33,"publisher":"Springer Science and Business Media LLC","license":[{"start":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T00:00:00Z","timestamp":1790726400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T00:00:00Z","timestamp":1790726400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Eur Spine J"],"DOI":"10.1007\/s00586-026-10377-6","type":"journal-article","created":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T00:29:25Z","timestamp":1790728165000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Cervicothoracic dumbbell ganglioneuroblastoma with spinal canal involvement and bone marrow metastasis: a case report and systematic review"],"prefix":"10.1007","author":[{"given":"Halit","family":"Alioglu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Omar","family":"Alomari","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-2788-2068","authenticated-orcid":false,"given":"Hamza","family":"Aksoy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eren Erdinc","family":"Falay","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fatima","family":"Abasova","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zuhal Kus","family":"Silav","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7314-7167","authenticated-orcid":false,"given":"Bekir Can","family":"Kendirlioglu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Berk","family":"\u00c7imeno\u011flu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Evren","family":"Aydogmus","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,9,30]]},"reference":[{"issue":"11","key":"10377_CR1","doi-asserted-by":"publisher","first-page":"702","DOI":"10.1177\/01455613221101941","volume":"103","author":"Z Zeng","year":"2024","unstructured":"Zeng Z, Liu J, Xu S, Qin G (2024) Ganglioneuroblastoma in the retropharyngeal space: a case report and literature review. Ear Nose Throat J 103(11):702\u2013706. https:\/\/doi.org\/10.1177\/01455613221101941","journal-title":"Ear Nose Throat J"},{"key":"10377_CR2","doi-asserted-by":"publisher","DOI":"10.7759\/CUREUS.33288","author":"CM Stevens","year":"2023","unstructured":"Stevens CM, Malone K, Dufrene K, Mclean W, Ramesh P, Talbot N et al (2023) Adrenal ganglioneuroblastoma of adult onset: a literature review. Cureus. https:\/\/doi.org\/10.7759\/CUREUS.33288. (PubMed PMID: 36751157)","journal-title":"Cureus"},{"issue":"2","key":"10377_CR3","doi-asserted-by":"publisher","first-page":"120","DOI":"10.1053\/j.semdp.2021.06.007","volume":"39","author":"JH Choi","year":"2022","unstructured":"Choi JH, Ro JY (2022) Mediastinal neuroblastoma, ganglioneuroblastoma, and ganglioneuroma: pathology review and diagnostic approach. Semin Diagn Pathol 39(2):120\u2013130. https:\/\/doi.org\/10.1053\/j.semdp.2021.06.007","journal-title":"Semin Diagn Pathol"},{"issue":"2","key":"10377_CR4","doi-asserted-by":"publisher","first-page":"84","DOI":"10.1016\/j.jus.2011.04.006","volume":"14","author":"S Alessi","year":"2011","unstructured":"Alessi S, Grignani M, Carone L (2011) Ganglioneuroblastoma: case report and review of the literature. J Ultrasound 14(2):84\u201388. https:\/\/doi.org\/10.1016\/j.jus.2011.04.006","journal-title":"J Ultrasound"},{"issue":"28","key":"10377_CR5","doi-asserted-by":"publisher","first-page":"3169","DOI":"10.1200\/JCO.2014.56.1621","volume":"32","author":"KT Vo","year":"2014","unstructured":"Vo KT, Matthay KK, Neuhaus J, London WB, Hero B, Ambros PF et al (2014) Clinical, biologic, and prognostic differences on the basis of primary tumor site in neuroblastoma: a report from the international neuroblastoma risk group project. J Clin Oncol 32(28):3169\u20133176. https:\/\/doi.org\/10.1200\/JCO.2014.56.1621","journal-title":"J Clin Oncol"},{"issue":"3","key":"10377_CR6","first-page":"27","volume":"116","author":"JZ Finklestein","year":"1972","unstructured":"Finklestein JZ, Gilchrist GS (1972) Recent advances in neuroblastoma. Calif Med 116(3):27\u201336","journal-title":"Calif Med"},{"key":"10377_CR7","doi-asserted-by":"publisher","DOI":"10.1186\/S40792-015-0062-0","author":"E Bolzacchini","year":"2015","unstructured":"Bolzacchini E, Martinelli B, Pinotti G (2015) Adult onset of ganglioneuroblastoma of the adrenal gland: case report and review of the literature. Surg Case Rep. https:\/\/doi.org\/10.1186\/S40792-015-0062-0","journal-title":"Surg Case Rep"},{"key":"10377_CR8","doi-asserted-by":"publisher","first-page":"n71","DOI":"10.1136\/bmj.n71","volume":"372","author":"MJ Page","year":"2021","unstructured":"Page MJ, McKenzie JE, Bossuyt PM, Boutron I, Hoffmann TC, Mulrow CD, Shamseer L, Tetzlaff JM, Akl EA, Brennan SE, Chou R, GlanvilleGrimshaw JJM, Hr\u00f3bjartsson A, Lalu MM, Li T, Loder EW, Mayo-Wilson E, McDonald S, McGuinness LA, Moher D (2021) The PRISMA 2020 statement: an updated guideline for reporting systematic reviews. BMJ 372:n71. https:\/\/doi.org\/10.1136\/bmj.n71","journal-title":"BMJ"},{"issue":"815","key":"10377_CR9","doi-asserted-by":"publisher","first-page":"746","DOI":"10.1136\/pgmj.69.815.746","volume":"69","author":"V Raina","year":"1993","unstructured":"Raina V, Kamble R, Tanwar R, Singh SP, Sharma S (1993) Spinal ganglioneuroblastoma\u2014complete response to chemotherapy alone. Postgrad Med J 69(815):746\u2013748. https:\/\/doi.org\/10.1136\/pgmj.69.815.746","journal-title":"Postgrad Med J"},{"issue":"4 Suppl","key":"10377_CR10","first-page":"875","volume":"16","author":"L Sibilla","year":"1995","unstructured":"Sibilla L, Martelli A, Farina L, Uggetti C, Zappoli F, Sessa F, Rodriguez y Baena R, Gaeltani P (1995) Ganglioneuroblastoma of the spinal cord. AJNR Am J Neuroradiol 16(4 Suppl):875\u2013877","journal-title":"AJNR Am J Neuroradiol"},{"issue":"3","key":"10377_CR11","doi-asserted-by":"publisher","first-page":"264","DOI":"10.1080\/026886900408513","volume":"14","author":"LN Tripathy","year":"2000","unstructured":"Tripathy LN, Forster DM, Timperley WR (2000) Ganglioneuroblastoma of the cauda equina. Br J Neurosurg 14(3):264\u2013266. https:\/\/doi.org\/10.1080\/026886900408513","journal-title":"Br J Neurosurg"},{"issue":"5","key":"10377_CR12","first-page":"663","volume":"60","author":"G Kanakaraj","year":"2005","unstructured":"Kanakaraj G, Zamzuri I, Abdullah J, Mohd Ghazali M, Mahamood Z, Shafiee A, Madhavan M, Rahman MT (2005) Extradural spinal cord and intraabdominal ganglioneuroblastoma. Med J Malays 60(5):663\u2013666","journal-title":"Med J Malays"},{"issue":"6","key":"10377_CR13","doi-asserted-by":"publisher","first-page":"966","DOI":"10.4103\/0028-3886.73778","volume":"58","author":"SK Singh","year":"2010","unstructured":"Singh SK, Srivastava C, Ojha BK, Chandra A, Husain N (2010) Ganglioneuroblastoma of the conus: a rare and aggressive tumor. Neurol India 58(6):966\u2013968. https:\/\/doi.org\/10.4103\/0028-3886.73778","journal-title":"Neurol India"},{"issue":"4","key":"10377_CR14","doi-asserted-by":"publisher","first-page":"457","DOI":"10.3171\/2011.5.SPINE10563","volume":"15","author":"WR Miele","year":"2011","unstructured":"Miele WR, Pfannl R, Kryzanski JT (2011) Primary holocord ganglioneuroblastoma: case report. J Neurosurg Spine 15(4):457\u2013463. https:\/\/doi.org\/10.3171\/2011.5.SPINE10563","journal-title":"J Neurosurg Spine"},{"issue":"1","key":"10377_CR15","doi-asserted-by":"publisher","first-page":"50","DOI":"10.14712\/18059694.2015.76","volume":"55","author":"B Akgun","year":"2012","unstructured":"Akgun B, Ates D, Kaplan M (2012) Ganglioneuroblastoma of the thoracic spinal cord: a very rare case report. Acta Medica (Hradec Kralove) 55(1):50\u201352. https:\/\/doi.org\/10.14712\/18059694.2015.76","journal-title":"Acta Medica (Hradec Kralove)"},{"issue":"4","key":"10377_CR16","doi-asserted-by":"publisher","first-page":"535","DOI":"10.4103\/0377-4929.107805","volume":"55","author":"K Tripathy","year":"2012","unstructured":"Tripathy K, Misra A, Gouda AK, Das S, Das B (2012) Primary intraspinal ganglioneuroblastoma of the thoracic spine: a rare case report. Indian J Pathol Microbiol 55(4):535\u2013537. https:\/\/doi.org\/10.4103\/0377-4929.107805","journal-title":"Indian J Pathol Microbiol"},{"issue":"3","key":"10377_CR17","doi-asserted-by":"publisher","first-page":"348","DOI":"10.4103\/0028-3886.98539","volume":"60","author":"S Thakar","year":"2012","unstructured":"Thakar S, Ghosal N, Hegde AS (2012) A cervicothoracic intramedullary ganglioneuroblastoma presenting with acute quadriparesis. Neurol India 60(3):348\u2013350. https:\/\/doi.org\/10.4103\/0028-3886.98539","journal-title":"Neurol India"},{"issue":"2","key":"10377_CR18","doi-asserted-by":"publisher","first-page":"270","DOI":"10.3171\/2014.4.SPINE121002","volume":"21","author":"Y Okudera","year":"2014","unstructured":"Okudera Y, Miyakoshi N, Sugawara T, Hongo M, Kasukawa Y, Ishikawa Y, Shimada Y (2014) Ganglioneuroblastoma of filum terminale: case report. J Neurosurg Spine 21(2):270\u2013274. https:\/\/doi.org\/10.3171\/2014.4.SPINE121002","journal-title":"J Neurosurg Spine"},{"key":"10377_CR19","first-page":"1572","volume":"4","author":"AA Mehra","year":"2019","unstructured":"Mehra AA, Raswan US, Mannan R (2019) Ganglioneuroblastoma: spinal with thoracic extension-a rare diagnosis. Ann Clin Case Rep 4:1572","journal-title":"Ann Clin Case Rep"},{"issue":"Suppl 3","key":"10377_CR20","doi-asserted-by":"publisher","DOI":"10.1002\/pbc.27670","volume":"66","author":"L Pio","year":"2019","unstructured":"Pio L, Blanc T, de Saint Denis T, Irtan S, Valteau-Couanet D, Michon J, Brisse H, Galmiche-Rolland L, Joyeux L, Odent T, Harte C, Glorion C, Zerah M, Sarnacki S (2019) Multidisciplinary surgical strategy for dumbbell neuroblastoma: a single-center experience of 32 cases. Pediatr Blood Cancer 66(Suppl 3):e27670. https:\/\/doi.org\/10.1002\/pbc.27670","journal-title":"Pediatr Blood Cancer"},{"key":"10377_CR21","doi-asserted-by":"publisher","first-page":"59","DOI":"10.12688\/f1000research.19895.1","volume":"9","author":"MMS IslamKhurram ZiaIfra asad","year":"2020","unstructured":"IslamKhurram ZiaIfra asad MMS et al (2020) Case report: primary ganglioneuroblastoma occurrence in lower thoracic spine (version 1; peer review: 1 approved, 1 approved with reservations). F1000Research 9:59. https:\/\/doi.org\/10.12688\/f1000research.19895.1","journal-title":"F1000Research"},{"issue":"19","key":"10377_CR22","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000038148","volume":"103","author":"YL Dai","year":"2024","unstructured":"Dai YL, Xiao L, Pan Z, He GQ, Gao J, Guo X, Huang Z (2024) Anti-Hu antibody associated paraneoplastic neurological syndrome in a child with ganglioneuroblastoma: a rare case report and literature review. Med (Baltimore) 103(19):e38148. https:\/\/doi.org\/10.1097\/MD.0000000000038148","journal-title":"Med (Baltimore)"},{"issue":"23","key":"10377_CR23","doi-asserted-by":"publisher","first-page":"2202","DOI":"10.1056\/NEJMra0804577","volume":"362","author":"JM Maris","year":"2010","unstructured":"Maris JM (2010) Recent advances in neuroblastoma. N Engl J Med 362(23):2202\u20132211. https:\/\/doi.org\/10.1056\/NEJMra0804577","journal-title":"N Engl J Med"},{"issue":"20","key":"10377_CR24","doi-asserted-by":"publisher","first-page":"18023","DOI":"10.1007\/s00432-023-05502-7","volume":"149","author":"A Anissi Eddaibouni","year":"2023","unstructured":"Anissi Eddaibouni A, Bennani Guebessi N, Cherkaoui S, Karkouri M, Khoubila N, Maataoui-Belabbes H (2023) Epidemiological and clinical characteristics of children with peripheral neuroblastic tumors: a study on a Moroccan population. J Cancer Res Clin Oncol 149(20):18023\u201318027. https:\/\/doi.org\/10.1007\/s00432-023-05502-7","journal-title":"J Cancer Res Clin Oncol"},{"issue":"8","key":"10377_CR25","doi-asserted-by":"publisher","first-page":"1369","DOI":"10.1002\/pbc.25028","volume":"61","author":"B De Bernardi","year":"2014","unstructured":"De Bernardi B, Quaglietta L, Haupt R, Castellano A, Tirtei E, Luksch R, Mastrangelo S, Viscardi E, Indolfi P, Cellini M, Tamburini A, Erminio G, Gandolfo C, Sorrentino S, Vetrella S, Gigliotti AR (2014) Neuroblastoma with symptomatic epidural compression in the infant: the AIEOP experience. Pediatr Blood Cancer 61(8):1369\u20131375. https:\/\/doi.org\/10.1002\/pbc.25028","journal-title":"Pediatr Blood Cancer"},{"issue":"6","key":"10377_CR26","doi-asserted-by":"publisher","first-page":"1230","DOI":"10.1002\/1097-0142(19860315)57:6<1230::AID-CNCR2820570628>3.0.CO;2-#","volume":"57","author":"PMPJAESL ZeltzerMarangosEvansSchneider","year":"1986","unstructured":"ZeltzerMarangosEvansSchneider PMPJAESL (1986) Serum neuron-specific enolase in children with neuroblastoma. Relationship to stage and disease course. Cancer 57(6):1230\u20131234","journal-title":"Cancer"},{"issue":"5","key":"10377_CR27","doi-asserted-by":"publisher","first-page":"282","DOI":"10.3322\/canjclin.33.5.282","volume":"33","author":"IM Ariel","year":"1983","unstructured":"Ariel IM (1983) Tumors of the peripheral nervous system. CA Cancer J Clin 33(5):282\u2013299. https:\/\/doi.org\/10.3322\/canjclin.33.5.282","journal-title":"CA Cancer J Clin"},{"issue":"10","key":"10377_CR28","doi-asserted-by":"publisher","DOI":"10.1101\/cshperspect.a014415","volume":"3","author":"M Huang","year":"2013","unstructured":"Huang M, Weiss WA (2013) Neuroblastoma and MYCN. Cold Spring Harb Perspect Med 3(10):a014415. https:\/\/doi.org\/10.1101\/cshperspect.a014415","journal-title":"Cold Spring Harb Perspect Med"},{"issue":"7","key":"10377_CR29","doi-asserted-by":"publisher","first-page":"1007","DOI":"10.1200\/JCO.2007.13.8925","volume":"27","author":"KK Matthay","year":"2009","unstructured":"Matthay KK, Reynolds CP, Seeger RC, Shimada H, Adkins ES, Haas-Kogan D, Gerbing RB, London WB, Villablanca JG (2009) Long-term results for children with high-risk neuroblastoma treated on a randomized trial of myeloablative therapy followed by 13-cis-retinoic acid: a children\u2019s oncology group study. J Clin Oncol 27(7):1007\u20131013. https:\/\/doi.org\/10.1200\/JCO.2007.13.8925","journal-title":"J Clin Oncol"},{"issue":"2","key":"10377_CR30","doi-asserted-by":"publisher","first-page":"289","DOI":"10.1200\/JCO.2008.16.6785","volume":"27","author":"SL Cohn","year":"2009","unstructured":"Cohn SL, Pearson AD, London WB, Monclair T, Ambros PF, Brodeur GM, Faldum A, Hero B, Iehara T, Machin D, Mosseri V, Simon T, Garaventa A, Castel V, Matthay KK, INRG Task Force (2009) The International Neuroblastoma Risk Group (INRG) classification system: an INRG Task Force report. J Clin Oncol 27(2):289\u2013297. https:\/\/doi.org\/10.1200\/JCO.2008.16.6785","journal-title":"J Clin Oncol"},{"issue":"1","key":"10377_CR31","doi-asserted-by":"publisher","first-page":"28","DOI":"10.1016\/s0360-3016(02)04506-6","volume":"56","author":"DA Haas-Kogan","year":"2003","unstructured":"Haas-Kogan DA, Swift PS, Selch M, Haase GM, Seeger RC, Gerbing RB, Stram DO, Matthay KK (2003) Impact of radiotherapy for high-risk neuroblastoma: a Children\u2019s Cancer Group study. Int J Radiat Oncol Biol Phys 56(1):28\u201339. https:\/\/doi.org\/10.1016\/s0360-3016(02)04506-6","journal-title":"Int J Radiat Oncol Biol Phys"},{"issue":"14","key":"10377_CR32","doi-asserted-by":"publisher","first-page":"1324","DOI":"10.1056\/NEJMoa0911123","volume":"363","author":"AL Yu","year":"2010","unstructured":"Yu AL, Gilman AL, Ozkaynak MF, London WB, Kreissman SG, Chen HX, Smith M, Anderson B, Villablanca JG, Matthay KK, Shimada H, Grupp SA, Seeger R, Reynolds CP, Buxton A, Reisfeld RA, Gillies SD, Cohn SL, Maris JM, Sondel PM, Children\u2019s Oncology Group (2010) Anti-GD2 antibody with GM-CSF, interleukin-2, and isotretinoin for neuroblastoma. N Engl J Med 363(14):1324\u20131334. https:\/\/doi.org\/10.1056\/NEJMoa0911123","journal-title":"N Engl J Med"},{"issue":"16","key":"10377_CR33","doi-asserted-by":"publisher","DOI":"10.3390\/jcm12165252","volume":"12","author":"A Wieczorek","year":"2023","unstructured":"Wieczorek A, \u017bebrowska U, Ussowicz M, Sok\u00f3\u0142 A, Stypi\u0144ska M, Dembowska-Bagi\u0144ska B, Pawi\u0144ska-W\u0105sikowska K, Balwierz W (2023) Dinutuximab beta maintenance therapy in patients with high-risk neuroblastoma in first-line and refractory\/relapsed settings-real-world data. J Clin Med 12(16):5252. https:\/\/doi.org\/10.3390\/jcm12165252","journal-title":"J Clin Med"}],"container-title":["European Spine Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00586-026-10377-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00586-026-10377-6","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00586-026-10377-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T13:03:48Z","timestamp":1790773428000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00586-026-10377-6"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9,30]]},"references-count":33,"alternative-id":["10377"],"URL":"https:\/\/doi.org\/10.1007\/s00586-026-10377-6","relation":{},"ISSN":["0940-6719","1432-0932"],"issn-type":[{"value":"0940-6719","type":"print"},{"value":"1432-0932","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,9,30]]},"assertion":[{"value":"15 June 2026","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"10 September 2026","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"16 September 2026","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"30 September 2026","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The authors declare no competing interests.","order":1,"name":"Ethics","label":"Conflict of interest","group":{"name":"EthicsHeading","label":"Declarations"}}]}}