{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T05:33:43Z","timestamp":1792733623807,"version":"4.5.0"},"reference-count":47,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2016,9,20]],"date-time":"2016-09-20T00:00:00Z","timestamp":1474329600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Eur J Orthop Surg Traumatol"],"published-print":{"date-parts":[[2017,2]]},"DOI":"10.1007\/s00590-016-1857-9","type":"journal-article","created":{"date-parts":[[2016,9,20]],"date-time":"2016-09-20T12:50:12Z","timestamp":1474375812000},"page":"205-211","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":125,"title":["Treatment for long bone metastases based on a systematic literature review"],"prefix":"10.1007","volume":"27","author":[{"given":"Costantino","family":"Errani","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andreas F.","family":"Mavrogenis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luca","family":"Cevolani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Silvia","family":"Spinelli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"Piccioli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giulio","family":"Maccauro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicola","family":"Baldini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Davide","family":"Donati","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2016,9,20]]},"reference":[{"key":"1857_CR1","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/j.ocl.2013.09.003","volume":"45","author":"FH Cheung","year":"2014","unstructured":"Cheung FH (2014) The practicing orthopedic surgeon\u2019s guide to managing long bone metastases. Orthop Clin North Am 45:109\u2013119","journal-title":"Orthop Clin North Am"},{"issue":"Suppl 4","key":"1857_CR2","first-page":"11","volume":"88","author":"KL Weber","year":"2006","unstructured":"Weber KL, Randall RL, Grossman S, Parvizi J (2006) Management of lower-extremity bone metastasis. J Bone Jt Surg Am 88(Suppl 4):11\u201319","journal-title":"J Bone Jt Surg Am"},{"issue":"20 Pt 2","key":"1857_CR3","doi-asserted-by":"crossref","first-page":"6243s","DOI":"10.1158\/1078-0432.CCR-06-0931","volume":"12","author":"RE Coleman","year":"2006","unstructured":"Coleman RE (2006) Clinical features of metastatic bone disease and risk of skeletal morbidity. Clin Cancer Res 12(20 Pt 2):6243s\u20136249s","journal-title":"Clin Cancer Res"},{"key":"1857_CR4","doi-asserted-by":"crossref","first-page":"2334","DOI":"10.1002\/cncr.22678","volume":"109","author":"KL Schulman","year":"2007","unstructured":"Schulman KL, Kohles J (2007) Economic burden of metastatic bone disease in the US. Cancer 109:2334\u20132342","journal-title":"Cancer"},{"key":"1857_CR5","doi-asserted-by":"crossref","first-page":"e19956","DOI":"10.1371\/journal.pone.0019956","volume":"6","author":"JA Forsberg","year":"2011","unstructured":"Forsberg JA, Eberhardt J, Boland PJ, Wedin R, Healey JH (2011) Estimating survival in patients with operable skeletal metastases: an application of a bayesian belief network. PLoS One 6:e19956","journal-title":"PLoS One"},{"key":"1857_CR6","doi-asserted-by":"crossref","first-page":"360","DOI":"10.1002\/jso.23654","volume":"110","author":"M Ratasvuori","year":"2014","unstructured":"Ratasvuori M, Wedin R, Hansen BH, Keller J, Trovik C, Zaikova O et al (2014) Prognostic role of en-bloc resection and late onset of bone metastasis in patients with bone-seeking carcinomas of the kidney, breast, lung, and prostate: SSG study on 672 operated skeletal metastases. J Surg Oncol 110:360\u2013365","journal-title":"J Surg Oncol"},{"key":"1857_CR7","doi-asserted-by":"crossref","first-page":"684","DOI":"10.1007\/s11999-011-2038-0","volume":"470","author":"N Harvey","year":"2012","unstructured":"Harvey N, Ahlmann ER, Allison DC, Wang L, Menendez LR (2012) Endoprostheses last longer than intramedullary devices in proximal femur metastases. Clin Orthop Relat Res 470:684\u2013691","journal-title":"Clin Orthop Relat Res"},{"key":"1857_CR8","doi-asserted-by":"crossref","first-page":"1653","DOI":"10.1302\/0301-620X.87B12.16629","volume":"87","author":"R Wedin","year":"2005","unstructured":"Wedin R, Bauer HCF (2005) Surgical treatment of skeletal metastatic lesions of the proximal femur: endoprosthesis or reconstruction nail? J Bone Jt Surg Br 87:1653\u20131657","journal-title":"J Bone Jt Surg Br"},{"issue":"Suppl","key":"1857_CR9","doi-asserted-by":"crossref","first-page":"S230","DOI":"10.1097\/01.blo.0000093849.72468.82","volume":"415","author":"WG Ward","year":"2003","unstructured":"Ward WG, Holsenbeck S, Dorey FJ, Spang J, Howe D (2003) Metastatic disease of the femur: surgical treatment. Clin Orthop Relat Res 415(Suppl):S230\u2013S244","journal-title":"Clin Orthop Relat Res"},{"issue":"3\u20134","key":"1857_CR10","first-page":"77","volume":"63","author":"KJ Hunt","year":"2006","unstructured":"Hunt KJ, Gollogly S, Randall RL (2006) Surgical fixation of pathologic fractures: an evaluation of evolving treatment methods. Bull Hosp Jt Dis 63(3\u20134):77\u201382","journal-title":"Bull Hosp Jt Dis"},{"key":"1857_CR11","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1080\/110241500750009366","volume":"166","author":"R Doorn van","year":"2000","unstructured":"van Doorn R, Stapert JW (2000) Treatment of impending and actual pathological femoral fractures with the long Gamma nail in The Netherlands. Eur J Surg Acta Chir 166:247\u2013254","journal-title":"Eur J Surg Acta Chir"},{"issue":"11","key":"1857_CR12","doi-asserted-by":"crossref","first-page":"1161","DOI":"10.1016\/j.injury.2010.09.018","volume":"41","author":"P Ruggieri","year":"2010","unstructured":"Ruggieri P, Mavrogenis AF, Casadei R, Errani C, Angelini A, Calabr\u00f2 T, Pala E, Mercuri M (2010) Protocol of surgical treatment of long bone pathological fractures. Injury 41(11):1161\u20131167","journal-title":"Injury"},{"issue":"3","key":"1857_CR13","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1007\/s00590-015-1726-y","volume":"26","author":"G Facchini","year":"2016","unstructured":"Facchini G, Di Tullio P, Battaglia M, Bartalena T, Tetta C, Errani C, Mavrogenis AF, Rossi G (2016) Palliative embolization for metastases of the spine. Eur J Orthop Surg Traumatol 26(3):247\u2013252","journal-title":"Eur J Orthop Surg Traumatol"},{"issue":"2","key":"1857_CR14","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1007\/s11547-012-0802-4","volume":"118","author":"G Rossi","year":"2013","unstructured":"Rossi G, Mavrogenis AF, Casadei R, Bianchi G, Romagnoli C, Rimondi E, Ruggieri P (2013) Embolisation of bone metastases from renal cancer. Radiol Med 118(2):291\u2013302","journal-title":"Radiol Med"},{"issue":"25","key":"1857_CR15","doi-asserted-by":"crossref","first-page":"6072","DOI":"10.1200\/JCO.2005.08.104","volume":"23","author":"SS Nathan","year":"2005","unstructured":"Nathan SS, Healey JH, Mellano D, Hoang B, Lewis I, Morris CD, Athanasian EA, Boland PJ (2005) Survival in patients operated on for pathologic fracture: implications for end-of-life orthopedic care. J Clin Oncol 23(25):6072\u20136082","journal-title":"J Clin Oncol"},{"key":"1857_CR16","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1097\/00003086-198912000-00027","volume":"249","author":"H Mirels","year":"1989","unstructured":"Mirels H (1989) Metastatic disease in long bones. A proposed scoring system for diagnosing impending pathologic fractures. Clin Orthop Relat Res 249:256\u2013264","journal-title":"Clin Orthop Relat Res"},{"key":"1857_CR17","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1186\/1471-2474-11-145","volume":"11","author":"A Fottner","year":"2010","unstructured":"Fottner A, Szalantzy M, Wirthmann L, St\u00e4hler M, Baur-Melnyk A, Jansson V et al (2010) Bone metastases from renal cell carcinoma: patient survival after surgical treatment. BMC Musculoskelet Disord 11:145","journal-title":"BMC Musculoskelet Disord"},{"key":"1857_CR18","doi-asserted-by":"crossref","first-page":"1794","DOI":"10.2106\/JBJS.F.00603","volume":"89","author":"PP Lin","year":"2007","unstructured":"Lin PP, Mirza AN, Lewis VO, Cannon CP, Tu S-M, Tannir NM et al (2007) Patient survival after surgery for osseous metastases from renal cell carcinoma. J Bone Jt Surg Am 89:1794\u20131801","journal-title":"J Bone Jt Surg Am"},{"key":"1857_CR19","doi-asserted-by":"crossref","first-page":"850","DOI":"10.1002\/jso.23134","volume":"106","author":"A Evenski","year":"2012","unstructured":"Evenski A, Ramasunder S, Fox W, Mounasamy V, Temple HT (2012) Treatment and survival of osseous renal cell carcinoma metastases. J Surg Oncol 106:850\u2013855","journal-title":"J Surg Oncol"},{"issue":"7","key":"1857_CR20","doi-asserted-by":"crossref","first-page":"e236","DOI":"10.3928\/01477447-20110526-07","volume":"34","author":"P Ruggieri","year":"2011","unstructured":"Ruggieri P, Mavrogenis AF, Angelini A, Mercuri M (2011) Metastases of the pelvis: does resection improve survival? Orthopedics 34(7):e236\u2013e244","journal-title":"Orthopedics"},{"key":"1857_CR21","doi-asserted-by":"crossref","first-page":"920","DOI":"10.1007\/s11999-011-2047-z","volume":"470","author":"M Steensma","year":"2012","unstructured":"Steensma M, Boland PJ, Morris CD, Athanasian E, Healey JH (2012) Endoprosthetic treatment is more durable for pathologic proximal femur fractures. Clin Orthop Relat Res 470:920\u2013926","journal-title":"Clin Orthop Relat Res"},{"key":"1857_CR22","doi-asserted-by":"crossref","first-page":"566","DOI":"10.1302\/0301-620X.86B4.14703","volume":"86","author":"YM Linden Van der","year":"2004","unstructured":"Van der Linden YM, Dijkstra PDS, Kroon HM, Lok JJ, Noordijk EM, Leer JWH et al (2004) Comparative analysis of risk factors for pathological fracture with femoral metastases. J Bone Jt Surg Br 86:566\u2013573","journal-title":"J Bone Jt Surg Br"},{"key":"1857_CR23","doi-asserted-by":"crossref","first-page":"361","DOI":"10.3928\/01477447-20080401-03","volume":"31","author":"CP Cannon","year":"2008","unstructured":"Cannon CP, Mirza AN, Lin PP, Lewis VO, Yasko AW (2008) Proximal femoral endoprosthesis for the treatment of metastatic. Orthopedics 31:361","journal-title":"Orthopedics"},{"key":"1857_CR24","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1302\/0301-620X.91B1.20448","volume":"91","author":"CR Chandrasekar","year":"2009","unstructured":"Chandrasekar CR, Grimer RJ, Carter SR, Tillman RM, Abudu A, Buckley L (2009) Modular endoprosthetic replacement for tumours of the proximal femur. J Bone Jt Surg Br 91:108\u2013112","journal-title":"J Bone Jt Surg Br"},{"key":"1857_CR25","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1016\/j.arth.2006.11.016","volume":"23","author":"H Selek","year":"2008","unstructured":"Selek H, Ba\u015farir K, Yildiz Y, Sa\u011flik Y (2008) Cemented endoprosthetic replacement for metastatic bone disease in the proximal femur. J Arthroplasty 23:112\u2013117","journal-title":"J Arthroplasty"},{"key":"1857_CR26","first-page":"62151","volume":"2007","author":"DH Park","year":"2007","unstructured":"Park DH, Jaiswal PK, Al-Hakim W, Aston WJS, Pollock RC, Skinner JA et al (2007) The use of massive endoprostheses for the treatment of bone metastases. Sarcoma 2007:62151","journal-title":"Sarcoma"},{"issue":"4","key":"1857_CR27","doi-asserted-by":"crossref","first-page":"404","DOI":"10.1016\/j.injury.2007.07.006","volume":"39","author":"J Nilsson","year":"2008","unstructured":"Nilsson J, Gustafson P (2008) Surgery for metastatic lesions of the femur: good outcome after 245 operations in 216 patients. Injury 39(4):404\u2013410","journal-title":"Injury"},{"issue":"8","key":"1857_CR28","doi-asserted-by":"crossref","first-page":"1049","DOI":"10.1016\/j.jse.2011.06.019","volume":"21","author":"R Wedin","year":"2012","unstructured":"Wedin R, Hansen BH, Laitinen M, Trovik C, Zaikova O, Bergh P, Kal\u00e9n A, Schwarz-Lausten G, Vult von Steyern F, Walloe A, Keller J, Weiss RJ (2012) Complications and survival after surgical treatment of 214 metastatic lesions of the humerus. J Shoulder Elbow Surg 21(8):1049\u20131055","journal-title":"J Shoulder Elbow Surg"},{"issue":"1","key":"1857_CR29","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1007\/s10195-008-0097-0","volume":"9","author":"C Scotti","year":"2008","unstructured":"Scotti C, Camnasio F, Peretti GM, Fontana F, Fraschini G (2008) Modular prostheses in the treatment of proximal humerus metastases: review of 40 cases. J Orthop Traumatol 9(1):5\u201310","journal-title":"J Orthop Traumatol"},{"issue":"4","key":"1857_CR30","doi-asserted-by":"crossref","first-page":"274","DOI":"10.3928\/01477447-20110228-12","volume":"34","author":"BJ Miller","year":"2011","unstructured":"Miller BJ, Soni EE, Gibbs CP, Scarborough MT (2011) Intramedullary nails for long bone metastases: why do they fail? Orthopedics 34(4):274","journal-title":"Orthopedics"},{"issue":"4","key":"1857_CR31","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1016\/j.suronc.2008.08.007","volume":"18","author":"BK Potter","year":"2009","unstructured":"Potter BK, Chow VE, Adams SC, Letson GD, Temple HT (2009) Endoprosthetic proximal femur replacement: metastatic versus primary tumors. Surg Oncol 18(4):343\u2013349","journal-title":"Surg Oncol"},{"issue":"5","key":"1857_CR32","doi-asserted-by":"crossref","first-page":"498","DOI":"10.1002\/jso.23277","volume":"107","author":"RJ Weiss","year":"2013","unstructured":"Weiss RJ, Ekstr\u00f6m W, Hansen BH, Keller J, Laitinen M, Trovik C, Zaikova O, Wedin R (2013) Pathological subtrochanteric fractures in 194 patients: a comparison of outcome after surgical treatment of pathological and non-pathological fractures. J Surg Oncol 107(5):498\u2013504","journal-title":"J Surg Oncol"},{"key":"1857_CR33","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1097\/BLO.0b013e31804f5474","volume":"459","author":"JL Finstein","year":"2007","unstructured":"Finstein JL, King JJ, Fox EJ, Ogilvie CM, Lackman RD (2007) Bipolar proximal femoral replacement prostheses for musculoskeletal neoplasms. Clin Orthop Relat Res 459:66\u201375","journal-title":"Clin Orthop Relat Res"},{"issue":"4","key":"1857_CR34","doi-asserted-by":"crossref","first-page":"1158","DOI":"10.1097\/TA.0b013e3181622bca","volume":"66","author":"K Sarahrudi","year":"2009","unstructured":"Sarahrudi K, Greitbauer M, Platzer P, Hausmann JT, Heinz T, V\u00e9csei V (2009) Surgical treatment of metastatic fractures of the femur: a retrospective analysis of 142 patients. J Trauma 66(4):1158\u20131163","journal-title":"J Trauma"},{"issue":"10","key":"1857_CR35","doi-asserted-by":"crossref","first-page":"1537","DOI":"10.1007\/s00264-010-1160-z","volume":"35","author":"M Zacherl","year":"2011","unstructured":"Zacherl M, Gruber G, Glehr M, Ofner-Kopeinig P, Radl R, Greitbauer M, Vecsei V, Windhager R (2011) Surgery for pathological proximal femoral fractures, excluding femoral head and neck fractures: resection vs. stabilisation. Int Orthop 35(10):1537\u20131543","journal-title":"Int Orthop"},{"issue":"5","key":"1857_CR36","doi-asserted-by":"crossref","first-page":"384","DOI":"10.3928\/01477447-20070501-09","volume":"30","author":"MW Manoso","year":"2007","unstructured":"Manoso MW, Frassica DA, Lietman ES, Frassica FJ (2007) Proximal femoral replacement for metastatic bone disease. Orthopedics 30(5):384\u2013388","journal-title":"Orthopedics"},{"issue":"3","key":"1857_CR37","doi-asserted-by":"crossref","first-page":"706","DOI":"10.1007\/s11999-012-2656-1","volume":"471","author":"HM Alvi","year":"2013","unstructured":"Alvi HM, Damron TA (2013) Prophylactic stabilization for bone metastases, myeloma, or lymphoma: do we need to protect the entire bone? Clin Orthop Relat Res 471(3):706\u2013714","journal-title":"Clin Orthop Relat Res"},{"issue":"2","key":"1857_CR38","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1002\/jso.22061","volume":"105","author":"AF Mavrogenis","year":"2012","unstructured":"Mavrogenis AF, Pala E, Romagnoli C, Romantini M, Calabro T, Ruggieri P (2012) Survival analysis of patients with femoral metastases. J Surg Oncol 105(2):135\u2013141","journal-title":"J Surg Oncol"},{"key":"1857_CR39","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1302\/2058-5241.1.000008","volume":"1","author":"JJ Willeumier","year":"2016","unstructured":"Willeumier JJ, van der Linden YM, van de Sande MAJ, Dijkstra PDS (2016) Treatment of pathological fractures of the long bones. EFORT Open Rev 1:136\u2013145","journal-title":"EFORT Open Rev"},{"issue":"3","key":"1857_CR40","doi-asserted-by":"crossref","first-page":"298","DOI":"10.1097\/00007632-200102010-00016","volume":"26","author":"K Tomita","year":"2001","unstructured":"Tomita K, Kawahara N, Kobayashi T, Yoshida A, Murakami H, Akamaru T (2001) Surgical strategy for spinal metastases. Spine (Phila Pa 1976) 26(3):298\u2013306","journal-title":"Spine (Phila Pa 1976)"},{"issue":"19","key":"1857_CR41","doi-asserted-by":"crossref","first-page":"2186","DOI":"10.1097\/01.brs.0000180401.06919.a5","volume":"30","author":"Y Tokuhashi","year":"2005","unstructured":"Tokuhashi Y, Matsuzaki H, Oda H, Oshima M, Ryu J (2005) A revised scoring system for preoperative evaluation of metastatic spine tumor prognosis. Spine (Phila Pa 1976) 30(19):2186\u20132191","journal-title":"Spine (Phila Pa 1976)"},{"issue":"2","key":"1857_CR42","doi-asserted-by":"crossref","first-page":"143","DOI":"10.3109\/17453679508995508","volume":"66","author":"HC Bauer","year":"1995","unstructured":"Bauer HC, Wedin R (1995) Survival after surgery for spinal and extremity metastases. Prognostication in 241 patients. Acta Orthop Scand 66(2):143\u2013146","journal-title":"Acta Orthop Scand"},{"issue":"21","key":"1857_CR43","doi-asserted-by":"crossref","first-page":"3388","DOI":"10.1200\/JCO.2005.05.0542","volume":"24","author":"D Rades","year":"2006","unstructured":"Rades D, Fehlauer F, Schulte R, Veninga T, Stalpers LJ, Basic H, Bajrovic A, Hoskin PJ, Tribius S, Wildfang I, Rudat V, Engenhart-Cabilic R, Karstens JH, Alberti W, Dunst J, Schild SE (2006) Prognostic factors for local control and survival after radiotherapy of metastatic spinal cord compression. J Clin Oncol 24(21):3388\u20133393","journal-title":"J Clin Oncol"},{"issue":"2","key":"1857_CR44","doi-asserted-by":"crossref","first-page":"320","DOI":"10.1002\/cncr.20756","volume":"103","author":"YM Linden van der","year":"2005","unstructured":"van der Linden YM, Dijkstra SP, Vonk EJ, Marijnen CA, Leer JW, Dutch Bone Metastasis Study Group (2005) Prediction of survival in patients with metastases in the spinal column: results based on a randomized trial of radiotherapy. Cancer 103(2):320\u2013328","journal-title":"Cancer"},{"issue":"10","key":"1857_CR45","doi-asserted-by":"crossref","first-page":"2816","DOI":"10.1002\/cncr.23888","volume":"113","author":"M Mizumoto","year":"2008","unstructured":"Mizumoto M, Harada H, Asakura H, Hashimoto T, Furutani K, Hashii H, Takagi T, Katagiri H, Takahashi M, Nishimura T (2008) Prognostic factors and a scoring system for survival after radiotherapy for metastases to the spinal column: a review of 544 patients at Shizuoka Cancer Center Hospital. Cancer 113(10):2816\u20132822","journal-title":"Cancer"},{"issue":"16","key":"1857_CR46","doi-asserted-by":"crossref","first-page":"3082","DOI":"10.1016\/j.ejca.2012.08.002","volume":"48","author":"A Lipton","year":"2012","unstructured":"Lipton A, Fizazi K, Stopeck AT, Henry DH, Brown JE, Yardley DA, Richardson GE, Siena S, Maroto P, Clemens M, Bilynskyy B, Charu V, Beuzeboc P, Rader M, Viniegra M, Saad F, Ke C, Braun A, Jun S (2012) Superiority of denosumab to zoledronic acid for prevention of skeletal-related events: a combined analysis of 3 pivotal, randomised, phase 3 trials. Eur J Cancer 48(16):3082\u20133092","journal-title":"Eur J Cancer"},{"issue":"5","key":"1857_CR47","doi-asserted-by":"crossref","first-page":"1359","DOI":"10.1002\/cam4.292","volume":"3","author":"H Katagiri","year":"2014","unstructured":"Katagiri H, Okada R, Takagi T, Takahashi M, Murata H, Harada H, Nishimura T, Asakura H, Ogawa H (2014) New prognostic factors and scoring system for patients with skeletal metastasis. Cancer Med 3(5):1359\u20131367","journal-title":"Cancer Med"}],"container-title":["European Journal of Orthopaedic Surgery & Traumatology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00590-016-1857-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00590-016-1857-9\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00590-016-1857-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,7,8]],"date-time":"2022-07-08T21:39:00Z","timestamp":1657316340000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00590-016-1857-9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,9,20]]},"references-count":47,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2017,2]]}},"alternative-id":["1857"],"URL":"https:\/\/doi.org\/10.1007\/s00590-016-1857-9","relation":{},"ISSN":["1633-8065","1432-1068"],"issn-type":[{"value":"1633-8065","type":"print"},{"value":"1432-1068","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,9,20]]}}}