{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T20:16:15Z","timestamp":1788380175982,"version":"build-2803163510"},"reference-count":24,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[2017,3,20]],"date-time":"2017-03-20T00:00:00Z","timestamp":1489968000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Eur J Orthop Surg Traumatol"],"published-print":{"date-parts":[[2017,5]]},"DOI":"10.1007\/s00590-017-1936-6","type":"journal-article","created":{"date-parts":[[2017,3,20]],"date-time":"2017-03-20T10:58:09Z","timestamp":1490007489000},"page":"503-511","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Adjacent segment pathology: natural history or effect of anterior cervical discectomy and fusion? A 10-year follow-up radiological multicenter study using an evaluation scale of the ageing spine"],"prefix":"10.1007","volume":"27","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0250-4205","authenticated-orcid":false,"given":"Alessandro","family":"Pesce","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Venceslao","family":"Wierzbicki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emanuele","family":"Piccione","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alessandro","family":"Frati","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonino","family":"Raco","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Riccardo","family":"Caruso","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2017,3,20]]},"reference":[{"issue":"4","key":"1936_CR1","doi-asserted-by":"publisher","first-page":"e35032","DOI":"10.1371\/journal.pone.0035032","volume":"7","author":"B Yang","year":"2012","unstructured":"Yang B, Li H, Zhang T, He X, Xu S (2012) The incidence of adjacent segment degeneration after cervical disc arthroplasty (CDA): a meta analysis of randomized controlled trials. PLoS ONE 7(4):e35032. doi:\n                        10.1371\/journal.pone.0035032","journal-title":"PLoS ONE"},{"issue":"7","key":"1936_CR2","doi-asserted-by":"publisher","first-page":"706","DOI":"10.1097\/BRS.0b013e31819c2003","volume":"34","author":"E Okada","year":"2009","unstructured":"Okada E, Matsumoto M, Ichihara D, Chiba K, Toyama Y, Fujiwara H, Momoshima S, Nishiwaki Y, Hashimoto T, Ogawa J, Watanabe M, Takahata T (2009) Aging of the cervical spine in healthy volunteers: a 10-year longitudinal magnetic resonance imaging study. Spine 34(7):706\u2013712 (Phila Pa 1976)","journal-title":"Spine"},{"issue":"12","key":"1936_CR3","doi-asserted-by":"publisher","first-page":"2763","DOI":"10.1007\/s00586-014-3673-4","volume":"24","author":"V Wierzbicki","year":"2015","unstructured":"Wierzbicki V, Pesce A, Marrocco L, Piccione E, Colonnese C, Caruso R (2015) How old is your cervical spine? Cervical spine biological age: a new evaluation scale. Eur Spine J 24(12):2763\u20132770. doi:\n                        10.1007\/s00586-014-3673-4\n                        \n                     (Epub 2014 Nov 23)","journal-title":"Eur Spine J"},{"issue":"11","key":"1936_CR4","doi-asserted-by":"publisher","first-page":"1940","DOI":"10.1007\/s00586-011-1864-9","volume":"20","author":"KJ Song","year":"2011","unstructured":"Song KJ, Choi BW, Jeon TS, Lee KB, Chang H (2011) Adjacent segment degenerative disease: is it due to disease progression or a fusion-associated phenomenon? Comparison between segments adjacent to the fused and non-fused segments. Eur Spine J 20(11):1940\u20131945. doi:\n                        10.1007\/s00586-011-1864-9\n                        \n                     (Epub 2011 Jun 8)","journal-title":"Eur Spine J"},{"issue":"12","key":"1936_CR5","doi-asserted-by":"publisher","first-page":"2339","DOI":"10.1007\/s00701-013-1902-y","volume":"155","author":"DC Noriega","year":"2013","unstructured":"Noriega DC, Kreuger A, Brotat M, Ardura F, Hernandez R, Mu\u00f1oz MF, Barrios C (2013) Long-term outcome of the Cloward procedure for single-level cervical degenerative spondylosis. Clinical and radiological assessment after a 22-year mean follow-up. Acta Neurochir (Wien) 155(12):2339\u20132344. doi:\n                        10.1007\/s00701-013-1902-y\n                        \n                     (Epub 2013 Oct 10)","journal-title":"Acta Neurochir (Wien)"},{"key":"1936_CR6","first-page":"223","volume":"96","author":"RA Robinson","year":"1955","unstructured":"Robinson RA, Smith GW (1955) Anterolateral cervical disc removal and interbody fusion for cervical disc syndrome. Bull Johns Hopkins Hosp 96:223\u2013224","journal-title":"Bull Johns Hopkins Hosp"},{"key":"1936_CR7","doi-asserted-by":"publisher","first-page":"1298","DOI":"10.2106\/00004623-199309000-00005","volume":"75","author":"HH Bohlman","year":"1993","unstructured":"Bohlman HH, Emery SE, Goodfellow DB, Jones PK (1993) Robinson anterior cervical discectomy and arthrodesis for cervical radiculopathy. Long-term follow-up of one hundred and twenty-two patients. J Bone Joint Surg Am 75:1298\u20131307","journal-title":"J Bone Joint Surg Am"},{"key":"1936_CR8","doi-asserted-by":"publisher","first-page":"190S","DOI":"10.1016\/j.spinee.2004.07.007","volume":"4","author":"AS Hillibrand","year":"2004","unstructured":"Hillibrand AS, Robbins M (2004) Adjacent segment degeneration and adjacent segment disease: the consequences of spinal fusion? Spine 4:190S\u2013194S (Phila Pa 1976)","journal-title":"Spine"},{"issue":"10","key":"1936_CR9","doi-asserted-by":"publisher","first-page":"2290","DOI":"10.1016\/j.spinee.2014.01.027","volume":"14","author":"JY Chung","year":"2014","unstructured":"Chung JY, Kim SK, Jung ST, Lee KB (2014) Clinical adjacent-segment pathology after anterior cervical discectomy and fusion: results after a minimum of 10-year follow-up. Spine J 14(10):2290\u20132298. doi:\n                        10.1016\/j.spinee.2014.01.027","journal-title":"Spine J"},{"issue":"7","key":"1936_CR10","doi-asserted-by":"publisher","first-page":"597","DOI":"10.1097\/BRS.0b013e318273a2ea","volume":"38","author":"XP Xia","year":"2013","unstructured":"Xia XP, Chen HL, Cheng HB (2013) Prevalence of adjacent segment degeneration after spine surgery: a systematic review and meta-analysis. Spine 38(7):597\u2013608. doi:\n                        10.1097\/BRS.0b013e318273a2ea\n                        \n                     (Phila Pa 1976)","journal-title":"Spine"},{"key":"1936_CR11","doi-asserted-by":"publisher","first-page":"519","DOI":"10.2106\/00004623-199904000-00009","volume":"81","author":"AS Hilibrand","year":"1999","unstructured":"Hilibrand AS, Carlson GD, Palumbo MA, Jones PK, Bohlman HH (1999) Radiculopathy and myelopathy at segments adjacent to the site of a previous anterior cervical arthrodesis. J Bone Joint Surg Am 81:519\u2013528","journal-title":"J Bone Joint Surg Am"},{"issue":"1","key":"1936_CR12","doi-asserted-by":"publisher","first-page":"3","DOI":"10.5435\/JAAOS-21-01-3","volume":"21","author":"SK Cho","year":"2013","unstructured":"Cho SK, Riew KD (2013) Adjacent segment disease following cervical spine surgery. J Am Acad Orthop Surg 21(1):3\u201311","journal-title":"J Am Acad Orthop Surg"},{"issue":"10","key":"1936_CR13","doi-asserted-by":"publisher","first-page":"1165","DOI":"10.1097\/01.brs.0000162441.23824.95","volume":"30","author":"AE Dmitriev","year":"2005","unstructured":"Dmitriev AE, Cunningham BW, Hu N, Sell G, Vigna F, McAfee PC (2005) Adjacent level intradiscal pressure and segmental kinematics following a cervical total disc arthroplasty: an in vitro human cadaveric model. Spine 30(10):1165\u20131172 (Phila Pa 1976)","journal-title":"Spine"},{"issue":"2","key":"1936_CR14","doi-asserted-by":"publisher","first-page":"215","DOI":"10.1007\/s10143-008-0164-2","volume":"32","author":"A Elsawaf","year":"2009","unstructured":"Elsawaf A, Mastronardi L, Roperto R, Bozzao A, Caroli M, Ferrante L (2009) Effect of cervical dynamics on adjacent segment degeneration after anterior cervical fusion with cages. Neurosurg Rev 32(2):215\u2013224. doi:\n                        10.1007\/s10143-008-0164-2\n                        \n                     (Epub 2008 Oct 10, discussion 224)","journal-title":"Neurosurg Rev"},{"issue":"2","key":"1936_CR15","doi-asserted-by":"publisher","first-page":"189","DOI":"10.1097\/BRS.0b013e3181913872","volume":"34","author":"A Nassr","year":"2009","unstructured":"Nassr A, Lee JY, Bashir RS, Rihn JA, Eck JC, Kang JD, Lim MR (2009) Does incorrect level needle localization during anterior cervical discectomy and fusion lead to accelerated disc degeneration? Spine 34(2):189\u2013192 (Phila Pa 1976)","journal-title":"Spine"},{"issue":"1","key":"1936_CR16","doi-asserted-by":"publisher","first-page":"82","DOI":"10.1016\/j.jocn.2013.02.039","volume":"21","author":"KM Lundine","year":"2014","unstructured":"Lundine KM, Davis G, Rogers M, Staples M, Quan G (2014) Prevalence of adjacent segment disc degeneration in patients undergoing anterior cervical discectomy and fusion based on pre-operative MRI findings. J Clin Neurosci 21(1):82\u201385. doi:\n                        10.1016\/j.jocn.2013.02.039\n                        \n                     (Epub 2013 Sep 11)","journal-title":"J Clin Neurosci"},{"issue":"1","key":"1936_CR17","doi-asserted-by":"publisher","first-page":"36","DOI":"10.1097\/BRS.0b013e3181b8a80d","volume":"35","author":"M Matsumoto","year":"2010","unstructured":"Matsumoto M, Okada E, Ichihara D, Watanabe K, Chiba K, Toyama Y, Fujiwara H, Momoshima S, Nishiwaki Y, Iwanami A, Ikegami T, Takahata T, Hashimoto T (2010) Anterior cervical decompression and fusion accelerates adjacent segment degeneration: comparison with asymptomatic volunteers in a ten-year magnetic resonance imaging follow-up study. Spine 35(1):36\u201343 (Phila Pa 1976)","journal-title":"Spine"},{"key":"1936_CR18","doi-asserted-by":"publisher","first-page":"2167","DOI":"10.1097\/00007632-199311000-00004","volume":"18","author":"H Baba","year":"1993","unstructured":"Baba H, Furusawa N, Imura S, Kawahara N, Tsuchiya H, Tomita K (1993) Late radiographic findings after anterior cervical fusion for spondylotic myeloradiculopathy. Spine 18:2167\u20132173 (Phila Pa 1976)","journal-title":"Spine"},{"issue":"2","key":"1936_CR19","doi-asserted-by":"publisher","first-page":"79","DOI":"10.1097\/00024720-200404000-00001","volume":"17","author":"J Goffin","year":"2004","unstructured":"Goffin J, Geusens E, Vantomme N, Quintens E, Waerzeggers Y, Depreitere B, van Calenbergh F, van Loon J (2004) Long-term follow-up after interbody fusion of the cervical spine. J Spinal Disord Tech 17(2):79\u201385","journal-title":"J Spinal Disord Tech"},{"issue":"1","key":"1936_CR20","first-page":"29","volume":"65","author":"DA Levin","year":"2007","unstructured":"Levin DA, Hale JJ, Bendo JA (2007) Adjacent segment degeneration following spinal fusion for degenerative disc disease. Bull NYU Hosp Jt Dis 65(1):29\u201336","journal-title":"Bull NYU Hosp Jt Dis"},{"issue":"3","key":"1936_CR21","doi-asserted-by":"publisher","first-page":"181","DOI":"10.1016\/S0720-048X(97)00165-4","volume":"27","author":"A Prescher","year":"1998","unstructured":"Prescher A (1998) Anatomy and pathology of the aging spine. Eur J Radiol 27(3):181\u2013195","journal-title":"Eur J Radiol"},{"issue":"6","key":"1936_CR22","doi-asserted-by":"publisher","first-page":"445","DOI":"10.1097\/BRS.0b013e31822174b3","volume":"37","author":"PD Nunley","year":"2012","unstructured":"Nunley PD, Jawahar A, Kerr EJ 3rd, Gordon CJ, Cavanaugh DA, Birdsong EM, Stocks M, Danielson G (2012) Factors affecting the incidence of symptomatic adjacent-level disease in cervical spine after total disc arthroplasty: 2- to 4-year follow-up of 3 prospective randomized trials. Spine 37(6):445\u2013451. doi:\n                        10.1097\/BRS.0b013e31822174b3\n                        \n                     (Phila Pa 1976)","journal-title":"Spine"},{"issue":"1","key":"1936_CR23","doi-asserted-by":"publisher","first-page":"36","DOI":"10.3171\/2012.9.SPINE12555","volume":"18","author":"D Coric","year":"2013","unstructured":"Coric D, Kim PK, Clemente JD, Boltes MO, Nussbaum M, James S (2013) Prospective randomized study of cervical arthroplasty and anterior cervical discectomy and fusion with long-term follow-up: results in 74 patients from a single site. J Neurosurg Spine 18(1):36\u201342","journal-title":"J Neurosurg Spine"},{"issue":"1","key":"1936_CR24","doi-asserted-by":"publisher","first-page":"1","DOI":"10.3171\/jns.1980.53.1.0001","volume":"53","author":"LD Lunsford","year":"1980","unstructured":"Lunsford LD, Bissonette DJ, Jannetta PJ, Sheptak PE, Zorub DS (1980) Anterior surgery for cervical disc disease. Part 1: treatment of lateral cervical disc herniation in 253 cases. J Neurosurg 53(1):1\u201311","journal-title":"J Neurosurg"}],"container-title":["European Journal of Orthopaedic Surgery & Traumatology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00590-017-1936-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00590-017-1936-6\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00590-017-1936-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,4,24]],"date-time":"2017-04-24T04:04:07Z","timestamp":1493006647000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00590-017-1936-6"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,3,20]]},"references-count":24,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2017,5]]}},"alternative-id":["1936"],"URL":"https:\/\/doi.org\/10.1007\/s00590-017-1936-6","relation":{},"ISSN":["1633-8065","1432-1068"],"issn-type":[{"value":"1633-8065","type":"print"},{"value":"1432-1068","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,3,20]]}}}