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Further, the study compares the calculated cost to the income received by the hospital for these patients and to the existing body of literature.\n<\/jats:p>\n<\/jats:sec><jats:sec>\n<jats:title>Methods<\/jats:title>\n<jats:p>This study employed direct inpatient costing analysis to estimate the cost of treating the open lower limb fractures incurred by 58 patients over the age of 65\u00a0years treated in our centre (Addenbrooke's Hospital, Cambridge University Hospitals NHS Trust) between March 2014 and March 2019.<\/jats:p>\n<\/jats:sec><jats:sec>\n<jats:title>Results<\/jats:title>\n<jats:p>The median cost of inpatient care calculated in this study was \u00a320,398 per patient, resulting in a financial loss to the hospital of \u00a35113 per patient. When the results were disaggregated by sex, the median cost for an open lower limb fracture in a male patient was \u00a320,886 compared to \u00a319,304 in a female patient. Data were also disaggregated by the site of injury, which produced a median cost for an open femur fracture of \u00a323,949, and \u00a324,549 and \u00a315,362 for open tibia and ankle fractures, respectively.<\/jats:p>\n<\/jats:sec><jats:sec>\n<jats:title>Conclusion<\/jats:title>\n<jats:p>This study provides a valuable estimate of the expense of treating open lower limb fractures in patients over the age of 65\u00a0years in a Major Trauma Centre in England. 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