{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,9]],"date-time":"2026-06-09T02:44:05Z","timestamp":1780973045844,"version":"3.54.1"},"reference-count":22,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2025,2,25]],"date-time":"2025-02-25T00:00:00Z","timestamp":1740441600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2025,2,25]],"date-time":"2025-02-25T00:00:00Z","timestamp":1740441600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Eur J Orthop Surg Traumatol"],"DOI":"10.1007\/s00590-025-04183-x","type":"journal-article","created":{"date-parts":[[2025,2,25]],"date-time":"2025-02-25T08:56:22Z","timestamp":1740473782000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Hypoalbuminemia increases risks for complications after surgical repair of nonunions and malunions"],"prefix":"10.1007","volume":"35","author":[{"given":"Charles C.","family":"Lin","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ibraheem","family":"Qureshi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Utkarsh","family":"Anil","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lawrence J.","family":"Lin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philipp","family":"Leucht","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,2,25]]},"reference":[{"issue":"3","key":"4183_CR1","doi-asserted-by":"publisher","first-page":"581","DOI":"10.1002\/jbmr.2072","volume":"29","author":"S Amin","year":"2014","unstructured":"Amin S, Achenbach SJ, Atkinson EJ, Khosla S, Melton LJ (2014) Trends in fracture incidence: a population-based study over 20 years. J Bone Miner Res Off J Am Soc Bone Miner Res 29(3):581\u2013589. https:\/\/doi.org\/10.1002\/jbmr.2072","journal-title":"J Bone Miner Res Off J Am Soc Bone Miner Res"},{"issue":"11","key":"4183_CR2","doi-asserted-by":"publisher","first-page":"e162775","DOI":"10.1001\/jamasurg.2016.2775","volume":"151","author":"R Zura","year":"2016","unstructured":"Zura R, Xiong Z, Einhorn T et al (2016) Epidemiology of fracture nonunion in 18 human bones. JAMA Surg 151(11):e162775. https:\/\/doi.org\/10.1001\/jamasurg.2016.2775","journal-title":"JAMA Surg"},{"key":"4183_CR3","doi-asserted-by":"publisher","first-page":"42","DOI":"10.1186\/1471-2474-14-42","volume":"14","author":"E Antonova","year":"2013","unstructured":"Antonova E, Le TK, Burge R, Mershon J (2013) Tibia shaft fractures: costly burden of nonunions. BMC Musculoskelet Disord 14:42. https:\/\/doi.org\/10.1186\/1471-2474-14-42","journal-title":"BMC Musculoskelet Disord"},{"issue":"12","key":"4183_CR4","doi-asserted-by":"publisher","first-page":"2845","DOI":"10.3390\/ijerph15122845","volume":"15","author":"CL Ekegren","year":"2018","unstructured":"Ekegren CL, Edwards ER, de Steiger R, Gabbe BJ (2018) Incidence, costs and predictors of non-union, delayed union and mal-union following long bone fracture. Int J Environ Res Public Health 15(12):2845. https:\/\/doi.org\/10.3390\/ijerph15122845","journal-title":"Int J Environ Res Public Health"},{"issue":"3","key":"4183_CR5","doi-asserted-by":"publisher","first-page":"269","DOI":"10.1055\/s-0036-1584575","volume":"30","author":"AF Kamath","year":"2017","unstructured":"Kamath AF, Nelson CL, Elkassabany N, Guo Z, Liu J (2017) Low albumin is a risk factor for complications after revision total knee arthroplasty. J Knee Surg 30(3):269\u2013275. https:\/\/doi.org\/10.1055\/s-0036-1584575","journal-title":"J Knee Surg"},{"issue":"10","key":"4183_CR6","doi-asserted-by":"publisher","first-page":"858","DOI":"10.22038\/ABJS.2021.60229.2976","volume":"10","author":"M Raad","year":"2022","unstructured":"Raad M, Best MJ, Rogers D et al (2022) Hypoalbuminemia and the higher risk of perioperative sentinel adverse events in patients undergoing total shoulder arthroplasty: a propensity score matched analysis. Arch Bone Jt Surg 10(10):858\u2013862. https:\/\/doi.org\/10.22038\/ABJS.2021.60229.2976","journal-title":"Arch Bone Jt Surg"},{"issue":"6","key":"4183_CR7","doi-asserted-by":"publisher","first-page":"552","DOI":"10.1016\/j.jor.2019.04.019","volume":"16","author":"GW Fryhofer","year":"2019","unstructured":"Fryhofer GW, Sloan M, Sheth NP (2019) Hypoalbuminemia remains an independent predictor of complications following total joint arthroplasty. J Orthop 16(6):552\u2013558. https:\/\/doi.org\/10.1016\/j.jor.2019.04.019","journal-title":"J Orthop"},{"issue":"4","key":"4183_CR8","doi-asserted-by":"publisher","first-page":"e126","DOI":"10.1097\/BOT.0000000000001952","volume":"35","author":"HM Phen","year":"2021","unstructured":"Phen HM, Jones C, Kravets VG et al (2021) Impact of frailty and malnutrition on outcomes after surgical fixation of lower extremity fractures in young patients. J Orthop Trauma 35(4):e126\u2013e133. https:\/\/doi.org\/10.1097\/BOT.0000000000001952","journal-title":"J Orthop Trauma"},{"issue":"10","key":"4183_CR9","doi-asserted-by":"publisher","first-page":"889","DOI":"10.2106\/JBJS.19.00511","volume":"102","author":"D Kishawi","year":"2020","unstructured":"Kishawi D, Schwarzman G, Mejia A, Hussain AK, Gonzalez MH (2020) Low preoperative albumin levels predict adverse outcomes after total joint arthroplasty. J Bone Joint Surg Am 102(10):889\u2013895. https:\/\/doi.org\/10.2106\/JBJS.19.00511","journal-title":"J Bone Joint Surg Am"},{"issue":"1","key":"4183_CR10","doi-asserted-by":"publisher","first-page":"15","DOI":"10.1016\/j.arth.2015.08.028","volume":"31","author":"DD Bohl","year":"2016","unstructured":"Bohl DD, Shen MR, Kayupov E, Della Valle CJ (2016) hypoalbuminemia independently predicts surgical site infection, pneumonia, length of stay, and readmission after total joint arthroplasty. J Arthroplasty 31(1):15\u201321. https:\/\/doi.org\/10.1016\/j.arth.2015.08.028","journal-title":"J Arthroplasty"},{"issue":"5","key":"4183_CR11","doi-asserted-by":"publisher","first-page":"281","DOI":"10.3928\/01477447-20220511-02","volume":"45","author":"RM Amin","year":"2022","unstructured":"Amin RM, Raad M, Rao SS, Guilbault R, Best MJ, Amanatullah DF (2022) Preoperative hypoalbuminemia is associated with early morbidity and mortality after revision total hip arthroplasty. Orthopedics 45(5):281\u2013286. https:\/\/doi.org\/10.3928\/01477447-20220511-02","journal-title":"Orthopedics"},{"issue":"5","key":"4183_CR12","doi-asserted-by":"publisher","first-page":"258","DOI":"10.1097\/BOT.0000000000001700","volume":"34","author":"DJ Ryan","year":"2020","unstructured":"Ryan DJ, Minhas SV, Konda S, Catalano LW (2020) Surgical site infection after open upper extremity fracture and the effect of urgent operative intervention. J Orthop Trauma 34(5):258\u2013262. https:\/\/doi.org\/10.1097\/BOT.0000000000001700","journal-title":"J Orthop Trauma"},{"issue":"2","key":"4183_CR13","doi-asserted-by":"publisher","first-page":"264","DOI":"10.1177\/1558944717736825","volume":"14","author":"EJ Golan","year":"2019","unstructured":"Golan EJ, De Tolla J, Culbertson-Scott MD, Krochak R, Choueka J (2019) Obesity is not a predictor of complications in upper extremity surgery. HAND 14(2):264\u2013270. https:\/\/doi.org\/10.1177\/1558944717736825","journal-title":"HAND"},{"issue":"2","key":"4183_CR14","doi-asserted-by":"publisher","first-page":"84","DOI":"10.1016\/j.jhsg.2020.01.004","volume":"2","author":"JH Wang","year":"2020","unstructured":"Wang JH, Du JY, Tu LA, Brown CC, Chepla K, Bafus BT (2020) A comparison of 30-day perioperative complications for open operative care of distal upper-extremity fractures treated by orthopedic versus plastic surgeons: a study of the national surgical quality improvement (NSQIP) database. J Hand Surg Glob Online 2(2):84\u201389. https:\/\/doi.org\/10.1016\/j.jhsg.2020.01.004","journal-title":"J Hand Surg Glob Online"},{"issue":"5","key":"4183_CR15","doi-asserted-by":"publisher","first-page":"996","DOI":"10.1053\/j.jfas.2021.12.027","volume":"61","author":"AJ Meyr","year":"2022","unstructured":"Meyr AJ, Sansosti LE (2022) an evaluation of basic demographic characteristics in foot and ankle surgery from the american college of surgeons national surgical quality improvement program. J Foot Ankle Surg 61(5):996\u20131000. https:\/\/doi.org\/10.1053\/j.jfas.2021.12.027","journal-title":"J Foot Ankle Surg"},{"issue":"10","key":"4183_CR16","doi-asserted-by":"publisher","first-page":"1620","DOI":"10.1016\/j.injury.2019.09.003","volume":"50","author":"JA Warren","year":"2019","unstructured":"Warren JA, Sundaram K, Hampton R, Billow D, Patterson B, Piuzzi NS (2019) Venous thromboembolism rates remained unchanged in operative lower extremity orthopaedic trauma patients from 2008 to 2016. Injury 50(10):1620\u20131626. https:\/\/doi.org\/10.1016\/j.injury.2019.09.003","journal-title":"Injury"},{"issue":"8","key":"4183_CR17","doi-asserted-by":"publisher","first-page":"393","DOI":"10.1097\/BOT.0000000000002609","volume":"37","author":"S Chinta","year":"2023","unstructured":"Chinta S, Fisher ND, Tejwani NC (2023) Does a modified frailty index predict 30-day complications after long-bone nonunion or malunion surgery? J Orthop Trauma 37(8):393\u2013400. https:\/\/doi.org\/10.1097\/BOT.0000000000002609","journal-title":"J Orthop Trauma"},{"issue":"1","key":"4183_CR18","doi-asserted-by":"publisher","first-page":"562","DOI":"10.1186\/s13018-021-02702-0","volume":"16","author":"Y Tan","year":"2021","unstructured":"Tan Y, Jiang L, Liu H, Pan Z, Wang H, Chen L (2021) The effect of preoperative hypoalbuminemia on complications after primary hip arthroplasty. J Orthop Surg 16(1):562. https:\/\/doi.org\/10.1186\/s13018-021-02702-0","journal-title":"J Orthop Surg"},{"issue":"5","key":"4183_CR19","doi-asserted-by":"publisher","first-page":"491","DOI":"10.1055\/s-0041-1739146","volume":"36","author":"ES Hur","year":"2023","unstructured":"Hur ES, Bohl DD, Della Valle CJ, Villalobos F, Gerlinger TL (2023) Hypoalbuminemia predicts adverse events following unicompartmental knee arthroplasty. J Knee Surg 36(5):491\u2013497. https:\/\/doi.org\/10.1055\/s-0041-1739146","journal-title":"J Knee Surg"},{"issue":"2","key":"4183_CR20","first-page":"27","volume":"39","author":"D Lee","year":"2019","unstructured":"Lee D, Lee R, Cross MT, Tran A, Kappa J, Moghtaderi S (2019) Low serum albumin levels are associated with increased 30-day cardiopulmonary complications, reoperation, and readmission rates following total shoulder arthroplasty. Iowa Orthop J 39(2):27\u201334","journal-title":"Iowa Orthop J"},{"issue":"6","key":"4183_CR21","doi-asserted-by":"publisher","first-page":"376","DOI":"10.1308\/rcsann.2016.0124","volume":"98","author":"O Riaz","year":"2016","unstructured":"Riaz O, Arshad R, Nisar S, Vanker R (2016) Serum albumin and fixation failure with cannulated hip screws in undisplaced intracapsular femoral neck fracture. Ann R Coll Surg Engl 98(6):376\u2013379. https:\/\/doi.org\/10.1308\/rcsann.2016.0124","journal-title":"Ann R Coll Surg Engl"},{"issue":"2","key":"4183_CR22","doi-asserted-by":"publisher","first-page":"433","DOI":"10.1007\/s41999-021-00598-x","volume":"13","author":"CF Frandsen","year":"2022","unstructured":"Frandsen CF, Glassou EN, Stilling M, Hansen TB (2022) Malnutrition, poor function and comorbidities predict mortality up to one year after hip fracture: a cohort study of 2800 patients. Eur Geriatr Med 13(2):433\u2013443. https:\/\/doi.org\/10.1007\/s41999-021-00598-x","journal-title":"Eur Geriatr Med"}],"container-title":["European Journal of Orthopaedic Surgery &amp; Traumatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00590-025-04183-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00590-025-04183-x","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00590-025-04183-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,29]],"date-time":"2025-12-29T13:39:49Z","timestamp":1767015589000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00590-025-04183-x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,2,25]]},"references-count":22,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2025,12]]}},"alternative-id":["4183"],"URL":"https:\/\/doi.org\/10.1007\/s00590-025-04183-x","relation":{},"ISSN":["1432-1068"],"issn-type":[{"value":"1432-1068","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,2,25]]},"assertion":[{"value":"16 November 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"25 January 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"25 February 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Philipp Leucht, MD, PhD: AAOS: Board or committee member; Ankasa Regenerative Therapeutics: Paid consultant; Stock or stock Options; Journal of Orthopedic Research: Editorial or governing board; Orthopedic Trauma Association: Board or committee member; Quince: Paid consultant; Springer: Publishing royalties, financial or material support; Stryker: Paid consultant.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interests"}}],"article-number":"76"}}