{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,2]],"date-time":"2026-02-02T13:43:07Z","timestamp":1770039787295,"version":"3.49.0"},"reference-count":20,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2025,4,25]],"date-time":"2025-04-25T00:00:00Z","timestamp":1745539200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2025,4,25]],"date-time":"2025-04-25T00:00:00Z","timestamp":1745539200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Eur J Orthop Surg Traumatol"],"DOI":"10.1007\/s00590-025-04291-8","type":"journal-article","created":{"date-parts":[[2025,4,25]],"date-time":"2025-04-25T03:53:05Z","timestamp":1745553185000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Comparing residual thrombosis and venous thromboembolism outcomes between patients treated with or without anticoagulant therapy for acute distal lower-limb deep vein thrombosis after total hip arthroplasty"],"prefix":"10.1007","volume":"35","author":[{"given":"Shine","family":"Tone","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yohei","family":"Naito","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroki","family":"Wakabayashi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akihiro","family":"Sudo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masahiro","family":"Hasegawa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2025,4,25]]},"reference":[{"issue":"8","key":"4291_CR1","doi-asserted-by":"publisher","first-page":"1239","DOI":"10.2106\/00004623-199408000-00015","volume":"76","author":"JR Lieberman","year":"1994","unstructured":"Lieberman JR, Geerts WH (1994) Prevention of venous thromboembolism after total hip and knee arthroplasty. J Bone Joint Surg Am 76(8):1239\u20131250. https:\/\/doi.org\/10.2106\/00004623-199408000-00015","journal-title":"J Bone Joint Surg Am"},{"issue":"6","key":"4291_CR2","doi-asserted-by":"publisher","first-page":"381S","DOI":"10.1378\/chest.08-0656","volume":"133","author":"WH Geerts","year":"2008","unstructured":"Geerts WH, Bergqvist D, Pineo GF, Heit JA, Samama CM, Lassen MR, Colwell CW (2008) Prevention of venous thromboembolism. Chest 133(6):381S-453S. https:\/\/doi.org\/10.1378\/chest.08-0656","journal-title":"Chest"},{"issue":"1","key":"4291_CR3","doi-asserted-by":"publisher","first-page":"259","DOI":"10.1016\/j.arth.2019.08.049","volume":"35","author":"JA Warren","year":"2020","unstructured":"Warren JA, Sundaram K, Anis HK, Kamath AF, Higuera CA, Piuzzi NS (2020) Have venous thromboembolism rates decreased in total hip and knee arthroplasty? J Arthroplasty 35(1):259\u2013264. https:\/\/doi.org\/10.1016\/j.arth.2019.08.049","journal-title":"J Arthroplasty"},{"issue":"8","key":"4291_CR4","doi-asserted-by":"publisher","first-page":"746","DOI":"10.2106\/JBJS.9408.ebo746","volume":"94","author":"JJ Jacobs","year":"2012","unstructured":"Jacobs JJ, Mont MA, Bozic KJ, Della Valle CJ, Goodman SB, Lewis CG et al (2012) American academy of orthopaedic surgeons clinical practice guideline on: preventing venous thromboembolic disease in patients undergoing elective hip and knee arthroplasty. J Bone Joint Surg Am 94(8):746\u2013747. https:\/\/doi.org\/10.2106\/JBJS.9408.ebo746","journal-title":"J Bone Joint Surg Am"},{"issue":"2","key":"4291_CR5","doi-asserted-by":"publisher","first-page":"7S","DOI":"10.1378\/chest.1412S3","volume":"141","author":"GH Guyatt","year":"2012","unstructured":"Guyatt GH, Akl EA, Crowther M, Gutterman DD, Schu\u00fcnemann HJ (2012) Executive summary. Chest 141(2):7S-47S. https:\/\/doi.org\/10.1378\/chest.1412S3","journal-title":"Chest"},{"issue":"20","key":"4291_CR6","doi-asserted-by":"publisher","first-page":"2191","DOI":"10.1001\/jama.2013.281053","volume":"310","author":"World Medical Association","year":"2013","unstructured":"World Medical Association (2013) World medical association declaration of Helsinki: ethical principles for medical research involving human subjects. JAMA 310(20):2191\u20132194. https:\/\/doi.org\/10.1001\/jama.2013.281053","journal-title":"JAMA"},{"issue":"4","key":"4291_CR7","doi-asserted-by":"publisher","first-page":"e323","DOI":"10.1016\/j.thromres.2010.03.018","volume":"126","author":"T Yamaguchi","year":"2010","unstructured":"Yamaguchi T, Hasegawa M, Niimi R, Sudo A (2010) Incidence and time course of asymptomatic deep vein thrombosis with fondaparinux in patients undergoing total joint arthroplasty. Thromb Res 126(4):e323-326. https:\/\/doi.org\/10.1016\/j.thromres.2010.03.018","journal-title":"Thromb Res"},{"issue":"9","key":"4291_CR8","doi-asserted-by":"publisher","first-page":"1280","DOI":"10.1302\/0301-620X.95B9.30905","volume":"95-B","author":"T Yamaguchi","year":"2013","unstructured":"Yamaguchi T, Matsumine A, Niimi R, Nakamura T, Matsubara T, Asanuma K et al (2013) Deep-vein thrombosis after resection of musculoskeletal tumours of the lower limb. Bone Joint J 95-B(9):1280\u20131284. https:\/\/doi.org\/10.1302\/0301-620X.95B9.30905","journal-title":"Bone Joint J"},{"issue":"11","key":"4291_CR9","doi-asserted-by":"publisher","first-page":"2458","DOI":"10.1111\/j.1538-7836.2010.04021.x","volume":"8","author":"T Fuji","year":"2010","unstructured":"Fuji T, Fujita S, Tachibana S, Kawai Y (2010) A dose-ranging study evaluating the oral factor Xa inhibitor edoxaban for the prevention of venous thromboembolism in patients undergoing total knee arthroplasty. J Thromb Haemost 8(11):2458\u20132468. https:\/\/doi.org\/10.1111\/j.1538-7836.2010.04021.x","journal-title":"J Thromb Haemost"},{"issue":"3","key":"4291_CR10","doi-asserted-by":"publisher","first-page":"642","DOI":"10.1160\/TH10-02-0142","volume":"104","author":"G Raskob","year":"2010","unstructured":"Raskob G, Cohen AT, Eriksson BI, Puskas D, Shi M, Bocanegra T et al (2010) Oral direct factor Xa inhibition with edoxaban for thromboprophylaxis after elective total hip replacement. A randomised double-blind dose-response study. Thromb Haemost 104(3):642\u2013649. https:\/\/doi.org\/10.1160\/TH10-02-0142","journal-title":"Thromb Haemost"},{"key":"4291_CR11","doi-asserted-by":"publisher","first-page":"452","DOI":"10.1038\/bmt.2012.244","volume":"48","author":"Y Kanda","year":"2013","unstructured":"Kanda Y (2013) Investigation of the freely-available easy-to-use software \u201cEZR\u201d (Easy R) for medical statistics. Bone Marrow Transplant 48:452\u2013458. https:\/\/doi.org\/10.1038\/bmt.2012.244","journal-title":"Bone Marrow Transplant"},{"issue":"9","key":"4291_CR12","doi-asserted-by":"publisher","first-page":"2205","DOI":"10.1007\/s11999-017-5394-6","volume":"475","author":"A Bala","year":"2017","unstructured":"Bala A, Huddleston JI 3rd, Goodman SB, Maloney WJ, Amanatullah DF (2017) Venous thromboembolism prophylaxis after TKA: aspirin, warfarin, enoxaparin, or Factor Xa inhibitors? Clin Orthop Relat Res 475(9):2205\u20132213. https:\/\/doi.org\/10.1007\/s11999-017-5394-6","journal-title":"Clin Orthop Relat Res"},{"issue":"2","key":"4291_CR13","doi-asserted-by":"publisher","first-page":"645","DOI":"10.1016\/j.arth.2016.09.033","volume":"32","author":"BT Venker","year":"2017","unstructured":"Venker BT, Ganti BR, Lin H, Lee ED, Nunley RM, Gage BF (2017) Safety and efficacy of new anticoagulants for the prevention of venous thromboembolism after hip and knee arthroplasty: a meta-analysis. J Arthroplasty 32(2):645\u2013652. https:\/\/doi.org\/10.1016\/j.arth.2016.09.033","journal-title":"J Arthroplasty"},{"key":"4291_CR14","doi-asserted-by":"publisher","unstructured":"Hokusai-VTE Investigators, B\u00fcller HR, D\u00e9cousus H, Grosso MA, Mercuri M, Middeldorp S, Prins MH et al (2013) Edoxaban versus warfarin for the treatment of symptomatic venous thromboembolism. N Engl J Med 369(15): 1406-1415. https:\/\/doi.org\/10.1056\/NEJMoa1306638.","DOI":"10.1056\/NEJMoa1306638"},{"key":"4291_CR15","doi-asserted-by":"publisher","unstructured":"EINSTEIN\u2013PE Investigators; B\u00fcller HR, Prins MH, Lensin AW, Decousus H, Jacobson BF, Minar E et al (2012) Oral rivaroxaban for the treatment of symptomatic pulmonary embolism. N Engl J Med 366(14): 1287-1297. https:\/\/doi.org\/10.1056\/NEJMoa1113572","DOI":"10.1056\/NEJMoa1113572"},{"key":"4291_CR16","doi-asserted-by":"publisher","unstructured":"Agnelli G, Buller HR, Cohen A, Curto M, Gallus AS, Johnson M et al; AMPLIFY-EXT Investigators (2013) Apixaban for extended treatment of venous thromboembolism. N Engl J Med 368(8): 699-708. https:\/\/doi.org\/10.1056\/NEJMoa1207541","DOI":"10.1056\/NEJMoa1207541"},{"issue":"4","key":"4291_CR17","doi-asserted-by":"publisher","first-page":"682","DOI":"10.1080\/14397595.2018.1504396","volume":"29","author":"T Mochizuki","year":"2019","unstructured":"Mochizuki T, Ikari K, Yano K, Hiroshima R, Ishibashi M, Okazaki K (2019) Outcome of direct oral anticoagulant treatment for acute lower limb deep venous thrombosis after total knee arthroplasty or total hip arthroplasty. Mod Rheumatol 29(4):682\u2013686. https:\/\/doi.org\/10.1080\/14397595.2018.1504396","journal-title":"Mod Rheumatol"},{"issue":"1","key":"4291_CR18","doi-asserted-by":"publisher","first-page":"39","DOI":"10.1302\/0301-620X.93B1.24984","volume":"93","author":"M Sukeik","year":"2011","unstructured":"Sukeik M, Alshryda S, Haddad FS, Mason JM (2011) Systematic review and meta-analysis of the use of tranexamic acid in total hip replacement. J Bone Joint Surg Br 93(1):39\u201346. https:\/\/doi.org\/10.1302\/0301-620X.93B1.24984","journal-title":"J Bone Joint Surg Br"},{"key":"4291_CR19","doi-asserted-by":"publisher","first-page":"81","DOI":"10.1186\/s12891-016-0923-0","volume":"17","author":"S Chen","year":"2016","unstructured":"Chen S, Wu K, Kong G, Feng W, Deng Z, Wang H (2016) The efficacy of topical tranexamic acid in total hip arthroplasty: a meta-analysis. BMC Musculoskelet Disord 17:81. https:\/\/doi.org\/10.1186\/s12891-016-0923-0","journal-title":"BMC Musculoskelet Disord"},{"key":"4291_CR20","doi-asserted-by":"publisher","first-page":"10","DOI":"10.1016\/j.ijsu.2016.05.064","volume":"32","author":"X Sun","year":"2016","unstructured":"Sun X, Dong Q, Zhang YG (2016) Intravenous versus topical tranexamic acid in primary total hip replacement: a systemic review and meta-analysis. Int J Surg 32:10\u201318. https:\/\/doi.org\/10.1016\/j.ijsu.2016.05.064","journal-title":"Int J Surg"}],"container-title":["European Journal of Orthopaedic Surgery &amp; Traumatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00590-025-04291-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00590-025-04291-8","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00590-025-04291-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,29]],"date-time":"2025-12-29T13:41:02Z","timestamp":1767015662000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00590-025-04291-8"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,4,25]]},"references-count":20,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2025,12]]}},"alternative-id":["4291"],"URL":"https:\/\/doi.org\/10.1007\/s00590-025-04291-8","relation":{},"ISSN":["1432-1068"],"issn-type":[{"value":"1432-1068","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,4,25]]},"assertion":[{"value":"2 January 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"4 April 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"25 April 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflicts of interest"}},{"value":"All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and\/or national research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards. This study was approved by Institutional Review Board at Mie University hospital (H2018-083).","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval"}},{"value":"Informed consent was obtained from all individual participants included in the study.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to participate"}},{"value":"Written informed consent to publish this information was obtained from study participants.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to publication"}}],"article-number":"167"}}