{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,28]],"date-time":"2026-08-28T21:23:16Z","timestamp":1787952196237,"version":"build-2784847793"},"reference-count":26,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2025,6,27]],"date-time":"2025-06-27T00:00:00Z","timestamp":1750982400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2025,6,27]],"date-time":"2025-06-27T00:00:00Z","timestamp":1750982400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Eur J Orthop Surg Traumatol"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>To describe nonunion and fracture-related infection (FRI) rates and patient-reported outcomes following operative treatment for distal femur fractures in young patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We retrospectively identified all patients (aged 18\u201350) who were operatively treated for a distal femur fracture between 2006 and 2023 with\u2009\u2265\u20093-month clinical follow-up at two Level 1 Trauma Centers. Outcomes included reoperation for nonunion and FRI; and PROMIS physical function (PF), depression, and anxiety (reference population mean: 50). Multiple linear regression was performed to identify factors associated with PROMIS-PF.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Eighty-six patients met inclusion criteria. The median age was 34\u00a0years, 71% were male, 42% had an open fracture, and for 38 patients PROMIS scores were collected at an average of 9.8\u00a0years after treatment. Eleven patients (13%) required reoperation for nonunion and 3 (3.5%) for FRI. Median PROMIS-PF was 47.0 (IQR: 41.2\u201352.4), depression 45.8 (IQR: 38.9\u201353.6), and anxiety 46.7 (IQR: 39.5\u201360.5). PROMIS-PF was lower than the reference population score (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.05). Increased age (1-year; \u00df: \u2212\u20090.39; 95%CI: \u2212\u20090.62 to \u2212\u20090.17;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001) and BMI (1-unit; \u00df: \u2212\u20090.59; 95%CI: \u2212\u20090.98 to \u2212\u20090.20;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.004) at time of injury were associated with worse PROMIS-PF scores and longer follow-up (1-year; \u00df: 0.79; 95% CI: 0.27 to 1.3;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.004) with better scores.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>One in 8 young patients with a distal femur fracture underwent reoperation for nonunion and one in 33 for FRI. Physical function scores were marginally lower than the reference population, whereas depression and anxiety scores were similar. The finding that physical function scores were more influenced by baseline patient factors than injury characteristics is important for prognostication and patient education. These results should be interpreted in the context of the small sample size, and future research with larger cohorts is needed to confirm these findings and better understand long-term functional outcomes in young patients following treatment of distal femur fractures.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s00590-025-04392-4","type":"journal-article","created":{"date-parts":[[2025,6,27]],"date-time":"2025-06-27T12:53:13Z","timestamp":1751028793000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Clinical and patient-reported outcomes of distal femur fracture fixation in adults aged 18\u201350 years"],"prefix":"10.1007","volume":"35","author":[{"given":"Wei Shao","family":"Tung","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert K.","family":"Wagner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jacob S.","family":"Borgida","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Niels","family":"Brinkman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maaz","family":"Muhammad","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adam N.","family":"Musick","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Austin T.","family":"Gregg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas J.","family":"Policicchio","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Derek S.","family":"Stenquist","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thuan V.","family":"Ly","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,6,27]]},"reference":[{"issue":"Suppl 3","key":"4392_CR1","doi-asserted-by":"publisher","first-page":"C62","DOI":"10.1016\/S0020-1383(00)80034-0","volume":"31","author":"O Martinet","year":"2000","unstructured":"Martinet O, Cordey J, Harder Y et al (2000) The epidemiology of fractures of the distal femur. 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Ly reports honoraria from the AO foundation and is a committee member for the Orthopaedic Trauma Association. For the remaining authors no conflicts of interest or sources of funding were declared.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing Interests"}}],"article-number":"284"}}