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The aim of this prospective study was to evaluate the clinical and radiological 2-year results of a novel metaphyseal anchored stemless shoulder system (Global Icon\u2122 Stemless Shoulder System, DePuy Synthes, Warsaw, IN, USA).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Thirty patients with primary osteoarthritis, 14 males and 6 females, were prospectively included in the study. Two-year follow-up data were analyzed for 20 patients. The average age and BMI were 63.4\u00a0years and 27.6\u00a0kg\/m2. The adjusted Constant-Murley Score (aCS), Oxford Shoulder Score (OSS), and EQ-5D-5L were used as primary endpoints to reflect postoperative clinical improvement. Postoperative radiographs in two planes were analyzed for implant loosening and migration.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      There was an overall clinical improvement 2\u00a0years postoperatively. The aCS increased from 58.3\u2009\u00b1\u200917.7 to 113.7\u2009\u00b1\u200915.6 points (p\u2009&lt;\u20090.0001). The OSS score improved from 25.5\u2009\u00b1\u20096.1 to 43.9\u2009\u00b1\u20096.1 points (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.0001). The EQ-5D-5L value score increased on average from 0.7\u2009\u00b1\u20090.2 to 0.9\u2009\u00b1\u20090.1 (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.0004). There was no implant loosening or migration. No revisions were required.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>In summary, the examined prosthesis system achieved very good clinical and radiographic results 2\u00a0years postoperatively without implant failure. Shoulder function and quality of life improved significantly. These results are encouraging for prostheses with bone-preserving designs which rely on peripheral humeral fixation, though more long-term results are needed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Level of evidence<\/jats:title>\n                    <jats:p>Level IV; Case Series; Treatment Study.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s00590-025-04405-2","type":"journal-article","created":{"date-parts":[[2025,7,4]],"date-time":"2025-07-04T13:10:28Z","timestamp":1751634628000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Promising short-term results after anatomical total shoulder arthroplasty for glenohumeral osteoarthritis with a novel stemless humeral implant in combination with a pegged all-polyethylene bone ingrowth glenoid component"],"prefix":"10.1007","volume":"35","author":[{"given":"Spiros","family":"Tsamassiotis","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tomas","family":"Smith","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karen","family":"Rychlik","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roman F.","family":"Karkosch","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hauke","family":"Horstmann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gunnar","family":"Jensen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,7,4]]},"reference":[{"issue":"4","key":"4405_CR1","doi-asserted-by":"publisher","first-page":"442","DOI":"10.1016\/j.xrrt.2022.08.001","volume":"2","author":"EM Marigi","year":"2022","unstructured":"Marigi EM, Elahi MA, Cancio-Bello AM, Duquin TR, Sperling JW (2022) Stemless anatomic total shoulder arthroplasty: surgical technique and review of the literature. 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Karen Rychlik is a paid consultant of the manufacturerof product which is subject of this study.  Hauke Horstmann received speaker fees from DePuy Synthes and participates as a faculty member during courses from DePuySynthes, which is related to the subject of this work.  Gunnar Jensen participates as a faculty member during courses from DePuySynthes, which is related to the subject of this work.  All other authors have no relevant financial or non-financial interests to disclose.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}],"article-number":"291"}}