{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,29]],"date-time":"2025-12-29T23:07:42Z","timestamp":1767049662186,"version":"3.48.0"},"reference-count":25,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2025,7,8]],"date-time":"2025-07-08T00:00:00Z","timestamp":1751932800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2025,7,8]],"date-time":"2025-07-08T00:00:00Z","timestamp":1751932800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Eur J Orthop Surg Traumatol"],"DOI":"10.1007\/s00590-025-04424-z","type":"journal-article","created":{"date-parts":[[2025,7,8]],"date-time":"2025-07-08T04:46:44Z","timestamp":1751950004000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Retrograde intramedullary nailing is an appropriate approach to pathologic femur fracture fixation: a retrospective analysis"],"prefix":"10.1007","volume":"35","author":[{"given":"Margaret A.","family":"Sinkler","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeremy M.","family":"Adelstein","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luc M.","family":"Fortier","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John T.","family":"Strony","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Logan M.","family":"Good","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ajay","family":"Mahenthiran","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrew","family":"Qi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rohan","family":"Patel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brandon","family":"Jonard","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2025,7,8]]},"reference":[{"key":"4424_CR1","doi-asserted-by":"publisher","first-page":"165","DOI":"10.1053\/ctrv.2000.0210","volume":"27","author":"RE Coleman","year":"2001","unstructured":"Coleman RE (2001) Metastatic bone disease: clinical features, pathophysiology and treatment strategies. Cancer Treat Rev 27:165\u2013176. https:\/\/doi.org\/10.1053\/ctrv.2000.0210","journal-title":"Cancer Treat Rev"},{"key":"4424_CR2","doi-asserted-by":"publisher","first-page":"883","DOI":"10.1002\/jso.25218","volume":"118","author":"JJ Willeumier","year":"2018","unstructured":"Willeumier JJ, van der Wal CWPG, Schoones JW et al (2018) Pathologic fractures of the distal femur: current concepts and treatment options. J Surg Oncol 118:883\u2013890. https:\/\/doi.org\/10.1002\/jso.25218","journal-title":"J Surg Oncol"},{"key":"4424_CR3","doi-asserted-by":"publisher","first-page":"291","DOI":"10.1177\/230949900701500309","volume":"15","author":"H Sharma","year":"2007","unstructured":"Sharma H, Bhagat S, McCaul J et al (2007) Intramedullary nailing for pathological femoral fractures. J Orthop Surg (Hong Kong) 15:291\u2013294. https:\/\/doi.org\/10.1177\/230949900701500309","journal-title":"J Orthop Surg (Hong Kong)"},{"issue":"Suppl 3","key":"4424_CR4","doi-asserted-by":"publisher","first-page":"S77","DOI":"10.1016\/j.injury.2018.09.044","volume":"49","author":"A Angelini","year":"2018","unstructured":"Angelini A, Trovarelli G, Berizzi A et al (2018) Treatment of pathologic fractures of the proximal femur. Injury 49(Suppl 3):S77\u2013S83. https:\/\/doi.org\/10.1016\/j.injury.2018.09.044","journal-title":"Injury"},{"key":"4424_CR5","doi-asserted-by":"publisher","first-page":"2000","DOI":"10.1007\/s11999-012-2724-6","volume":"471","author":"M Steensma","year":"2013","unstructured":"Steensma M, Healey JH (2013) Trends in the surgical treatment of pathologic proximal femur fractures among musculoskeletal tumor society members. Clin Orthop Relat Res 471:2000\u20132006. https:\/\/doi.org\/10.1007\/s11999-012-2724-6","journal-title":"Clin Orthop Relat Res"},{"key":"4424_CR6","doi-asserted-by":"publisher","first-page":"161","DOI":"10.1097\/00005131-200103000-00003","volume":"15","author":"WM Ricci","year":"2001","unstructured":"Ricci WM, Bellabarba C, Evanoff B et al (2001) Retrograde versus antegrade nailing of femoral shaft fractures. J Orthop Trauma 15:161\u2013169. https:\/\/doi.org\/10.1097\/00005131-200103000-00003","journal-title":"J Orthop Trauma"},{"key":"4424_CR7","doi-asserted-by":"publisher","first-page":"218","DOI":"10.22038\/ABJS.2022.67164.3215","volume":"11","author":"G Breyer","year":"2023","unstructured":"Breyer G, Usmani K, Hwang R et al (2023) Knee pain and functional outcomes after retrograde femoral nailing: a retrospective review. Arch Bone Jt Surg 11:218\u2013224. https:\/\/doi.org\/10.22038\/ABJS.2022.67164.3215","journal-title":"Arch Bone Jt Surg"},{"key":"4424_CR8","doi-asserted-by":"publisher","first-page":"253","DOI":"10.1177\/230949900601400305","volume":"14","author":"KN Acharya","year":"2006","unstructured":"Acharya KN, Rao MR (2006) Retrograde nailing for distal third femoral shaft fractures: a prospective study. J Orthop Surg (Hong Kong) 14:253\u2013258. https:\/\/doi.org\/10.1177\/230949900601400305","journal-title":"J Orthop Surg (Hong Kong)"},{"key":"4424_CR9","doi-asserted-by":"publisher","first-page":"1499","DOI":"10.1007\/s11999-014-4064-1","volume":"473","author":"B Moon","year":"2015","unstructured":"Moon B, Lin P, Satcher R et al (2015) Intramedullary nailing of femoral diaphyseal metastases: Is it necessary to protect the femoral neck? Clin Orthop Relat Res 473:1499\u20131502. https:\/\/doi.org\/10.1007\/s11999-014-4064-1","journal-title":"Clin Orthop Relat Res"},{"issue":"Suppl 4","key":"4424_CR10","doi-asserted-by":"publisher","first-page":"11","DOI":"10.2106\/JBJS.F.00635","volume":"88","author":"KL Weber","year":"2006","unstructured":"Weber KL, Randall RL, Grossman S, Parvizi J (2006) Management of lower-extremity bone metastasis. J Bone Joint Surg Am 88(Suppl 4):11\u201319. https:\/\/doi.org\/10.2106\/JBJS.F.00635","journal-title":"J Bone Joint Surg Am"},{"issue":"Suppl 1","key":"4424_CR11","doi-asserted-by":"publisher","first-page":"S1","DOI":"10.1097\/BOT.0000000000001063","volume":"32","author":"EG Meinberg","year":"2018","unstructured":"Meinberg EG, Agel J, Roberts CS et al (2018) Fracture and dislocation classification compendium-2018. J Orthop Trauma 32(Suppl 1):S1\u2013S170. https:\/\/doi.org\/10.1097\/BOT.0000000000001063","journal-title":"J Orthop Trauma"},{"key":"4424_CR12","doi-asserted-by":"publisher","first-page":"2604","DOI":"10.1016\/j.arth.2017.02.005","volume":"32","author":"VA Cheuy","year":"2017","unstructured":"Cheuy VA, Foran JRH, Paxton RJ et al (2017) Arthrofibrosis associated with total knee arthroplasty. J Arthroplasty 32:2604\u20132611. https:\/\/doi.org\/10.1016\/j.arth.2017.02.005","journal-title":"J Arthroplasty"},{"key":"4424_CR13","doi-asserted-by":"publisher","first-page":"1622","DOI":"10.1007\/s11999-013-2790-4","volume":"471","author":"Z Xing","year":"2013","unstructured":"Xing Z, Moon BS, Satcher RL et al (2013) A long femoral stem is not always required in hip arthroplasty for patients with proximal femur metastases. Clin Orthop Relat Res 471:1622\u20131627. https:\/\/doi.org\/10.1007\/s11999-013-2790-4","journal-title":"Clin Orthop Relat Res"},{"key":"4424_CR14","doi-asserted-by":"publisher","first-page":"e465","DOI":"10.5435\/JAAOS-D-20-00315","volume":"29","author":"AL Boden","year":"2021","unstructured":"Boden AL, Patel M, Hoyt A et al (2021) Development of distal femoral metastasis is rare in cases of isolated proximal femoral metastases. J Am Acad Orthop Surg 29:e465\u2013e470. https:\/\/doi.org\/10.5435\/JAAOS-D-20-00315","journal-title":"J Am Acad Orthop Surg"},{"key":"4424_CR15","doi-asserted-by":"publisher","first-page":"706","DOI":"10.1007\/s11999-012-2656-1","volume":"471","author":"HM Alvi","year":"2013","unstructured":"Alvi HM, Damron TA (2013) Prophylactic stabilization for bone metastases, myeloma, or lymphoma: Do we need to protect the entire bone? Clin Orthop Relat Res 471:706\u2013714. https:\/\/doi.org\/10.1007\/s11999-012-2656-1","journal-title":"Clin Orthop Relat Res"},{"key":"4424_CR16","doi-asserted-by":"publisher","first-page":"287","DOI":"10.1097\/01.blo.0000191270.50033.3a","volume":"443","author":"RL Randall","year":"2006","unstructured":"Randall RL, Aoki SK, Olson PR, Bott SI (2006) Complications of cemented long-stem hip arthroplasties in metastatic bone disease. Clin Orthop Relat Res 443:287\u2013295. https:\/\/doi.org\/10.1097\/01.blo.0000191270.50033.3a","journal-title":"Clin Orthop Relat Res"},{"key":"4424_CR17","doi-asserted-by":"publisher","first-page":"211","DOI":"10.1097\/00005373-199402000-00012","volume":"36","author":"RR van der Hulst","year":"1994","unstructured":"van der Hulst RR, van den Wildenberg FA, Vroemen JP, Greve JW (1994) Intramedullary nailing of (impending) pathologic fractures. J Trauma 36:211\u2013215. https:\/\/doi.org\/10.1097\/00005373-199402000-00012","journal-title":"J Trauma"},{"key":"4424_CR18","doi-asserted-by":"publisher","first-page":"1158","DOI":"10.1097\/TA.0b013e3181622bca","volume":"66","author":"K Sarahrudi","year":"2009","unstructured":"Sarahrudi K, Greitbauer M, Platzer P et al (2009) Surgical treatment of metastatic fractures of the femur: a retrospective analysis of 142 patients. J Trauma 66:1158\u20131163. https:\/\/doi.org\/10.1097\/TA.0b013e3181622bca","journal-title":"J Trauma"},{"key":"4424_CR19","doi-asserted-by":"publisher","first-page":"307","DOI":"10.4055\/cios.2012.4.4.307","volume":"4","author":"J Kim","year":"2012","unstructured":"Kim J, Kang S-B, Nam K et al (2012) Retrograde intramedullary nailing for distal femur fracture with osteoporosis. Clin Orthop Surg 4:307\u2013312. https:\/\/doi.org\/10.4055\/cios.2012.4.4.307","journal-title":"Clin Orthop Surg"},{"key":"4424_CR20","doi-asserted-by":"publisher","first-page":"135","DOI":"10.1002\/jso.22061","volume":"105","author":"AF Mavrogenis","year":"2012","unstructured":"Mavrogenis AF, Pala E, Romagnoli C et al (2012) Survival analysis of patients with femoral metastases. J Surg Oncol 105:135\u2013141. https:\/\/doi.org\/10.1002\/jso.22061","journal-title":"J Surg Oncol"},{"key":"4424_CR21","doi-asserted-by":"publisher","first-page":"128","DOI":"10.1097\/00003086-199901000-00016","volume":"358","author":"R Wedin","year":"1999","unstructured":"Wedin R, Bauer HC, Wers\u00e4ll P (1999) Failures after operation for skeletal metastatic lesions of long bones. Clin Orthop Relat Res 358:128\u2013139","journal-title":"Clin Orthop Relat Res"},{"key":"4424_CR22","doi-asserted-by":"publisher","first-page":"523","DOI":"10.1097\/BOT.0b013e31813347ac","volume":"21","author":"MC Tucker","year":"2007","unstructured":"Tucker MC, Schwappach JR, Leighton RK et al (2007) Results of femoral intramedullary nailing in patients who are obese versus those who are not obese: a prospective multicenter comparison study. J Orthop Trauma 21:523\u2013529. https:\/\/doi.org\/10.1097\/BOT.0b013e31813347ac","journal-title":"J Orthop Trauma"},{"key":"4424_CR23","doi-asserted-by":"publisher","first-page":"533","DOI":"10.1016\/s0020-1383(02)00035-9","volume":"33","author":"GM Spence","year":"2002","unstructured":"Spence GM, Dunning MT, Cannon SR, Briggs TW (2002) The hazard of retrograde nailing in pathological fractures: three cases involving primary musculoskeletal malignancy. Injury 33:533\u2013538. https:\/\/doi.org\/10.1016\/s0020-1383(02)00035-9","journal-title":"Injury"},{"key":"4424_CR24","doi-asserted-by":"publisher","first-page":"219","DOI":"10.1097\/00003086-200201000-00026","volume":"394","author":"BM Scholl","year":"2002","unstructured":"Scholl BM, Jaffe KA (2002) Oncologic uses of the retrograde femoral nail. Clin Orthop Relat Res 394:219\u2013226. https:\/\/doi.org\/10.1097\/00003086-200201000-00026","journal-title":"Clin Orthop Relat Res"},{"key":"4424_CR25","doi-asserted-by":"publisher","first-page":"1154","DOI":"10.1016\/j.injury.2012.03.011","volume":"43","author":"M el Moumni","year":"2012","unstructured":"el Moumni M, Voogd EH, ten Duis HJ, Wendt KW (2012) Long-term functional outcome following intramedullary nailing of femoral shaft fractures. Injury 43:1154\u20131158. https:\/\/doi.org\/10.1016\/j.injury.2012.03.011","journal-title":"Injury"}],"container-title":["European Journal of Orthopaedic Surgery & Traumatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00590-025-04424-z.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00590-025-04424-z","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00590-025-04424-z.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,29]],"date-time":"2025-12-29T23:03:16Z","timestamp":1767049396000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00590-025-04424-z"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,7,8]]},"references-count":25,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2025,12]]}},"alternative-id":["4424"],"URL":"https:\/\/doi.org\/10.1007\/s00590-025-04424-z","relation":{},"ISSN":["1432-1068"],"issn-type":[{"type":"electronic","value":"1432-1068"}],"subject":[],"published":{"date-parts":[[2025,7,8]]},"assertion":[{"value":"14 March 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"30 June 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"8 July 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}],"article-number":"295"}}