{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T15:09:40Z","timestamp":1787065780902,"version":"build-2736575974"},"reference-count":53,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2025,12,24]],"date-time":"2025-12-24T00:00:00Z","timestamp":1766534400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2025,12,24]],"date-time":"2025-12-24T00:00:00Z","timestamp":1766534400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"name":"University of Warwick Research Development Fund"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Eur J Orthop Surg Traumatol"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Total hip replacement (THR) can be performed conventionally or with the assistance of computer guidance systems. We aimed to compare the risk of revision for all-causes and dislocation, and differences in Oxford Hip Score (OHS) and health-related quality of life (EQ-5D-3L) following primary THR performed conventionally versus with the assistance of computer guidance systems.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We performed an observational study using National Joint Registry data. Adult patients who underwent primary THR for osteoarthritis between 2003 and 2020 were included. The co-primary analyses were revision for all-causes and dislocation. Secondary analyses were differences in OHS and EQ-5D-3L. Weights based on propensity scores were generated. Cox proportional hazards and generalised linear models were used to assess outcomes of revision, OHS, and EQ-5D-3L. Effective sample sizes (ESS) were computed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Risk of revision for all-causes comparing computer guided and conventional THR were similar (HR 0.947, 95% CI 0.698\u20131.283,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.726, ESS 7235). However, sensitivity analysis restricting to the five most commonly used combination of prosthesis brands demonstrated reduced revision risk in favour of computer guidance (HR 0.446, 95% CI 0.231\u20130.858,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.016, ESS 3993). There was no difference in revision for dislocation between groups (HR 0.929, 95% CI 0.512\u20131.688,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.810, ESS 7235). Compared to conventional THR, the use of computer guidance increased OHS by 0.931 (95% CI 0.308\u20131.554,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.003, ESS 2112) however there were no differences in EQ-5D-3L (0.007, 95% CI \u22120.008\u20130.023,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.356, ESS 2929). Incidence of intra-operative complications was significantly fewer during computer guided THR (0.51% versus 0.96%,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.006).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>There were no differences in revision for all-causes and dislocation between computer guided and conventional THR. However, sensitivity analysis considering only the five most commonly used prosthesis brands demonstrated a reduced risk of revision for all-causes favouring computer guided THR. Furthermore, computer guidance was associated with a significant but minimal improvement in OHS and a lower risk of intra-operative complications, without differences in EQ-5D-3L. Although these findings suggest potential for computer guided THR to improve implant survivorship and reduce intra-operative complications, they require cautious interpretation given the limitations inherent to observational study designs and registry based analyses.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s00590-025-04622-9","type":"journal-article","created":{"date-parts":[[2025,12,24]],"date-time":"2025-12-24T07:18:38Z","timestamp":1766560718000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["The effect of computer guided total hip replacement on risk of revision, Oxford Hip Score, and health related quality of life: an analysis of National Joint Registry data"],"prefix":"10.1007","volume":"36","author":[{"given":"Muhamed M.","family":"Farhan-Alanie","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel","family":"Gallacher","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Craig","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James","family":"Griffin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jakub","family":"Kozdryk","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James","family":"Mason","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter D. 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PW leads RACER-Hip (about robotic-assisted hip replacement). These studies are funded by the UK National Institute for Health Research (NIHR), but for which Stryker, have funded treatment costs and some imaging and training costs. JM is also a co-applicant for these three studies. For all of these studies, the full independence of the study team (AM, PW, and JM included) are fully protected by legal agreements agreed between the parties and approved by NIHR.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"With support under Section 251 of the NHS Act 2006, the Ethics and Confidentiality Committee (ECC), (now the Health Research Authority Confidentiality Advisory Group) allows the NJR to collect patient data where consent is indicated as \u2018Not Recorded\u2019. Before Personal Data and Sensitive Personal Data is recorded, express written patient consent is provided. The NJR records patient consent as either \u2018Yes\u2019, \u2018No\u2019, or \u2018Not Recorded\u2019.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}}],"article-number":"51"}}