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R. China and have been performed in accordance with the 1964 Helsinki declaration and its later amendments or comparable ethical standards. All samples were collected with informed consent of all subjects. There is no security and privacy violation to the patient\u2019s health in our study.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"All procedures followed were in accordance with the ethical standards of the responsible committee on human experimentation (institutional and national) and with the 1975 Helsinki declaration, as revised in 2008 (5).","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Human and animal rights"}},{"value":"Informed consent was obtained from all individual participants included in the study.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed consent"}}]}}