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The study was approved by the ethical committee (CPP Est-III, #2018-A01721-54) and registered on clinicaltrials.gov (#NCT03744039).","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"Written informed consent was obtained from all patients before participation.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to participate"}}]}}