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Diabetic foot ulcers are characterized by their complex aetiology, pose a grave threat to life and impose enormous social and economic burdens, thus becoming a critical issue in public health that urgently requires attention. By accurately predicting the risk of diabetic foot and implementing early intervention strategies, this study aimed to reduce its incidence and mortality rates.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This study employed a systematic review and comprehensive analysis framework, conducted extensive searches of electronic databases (including PubMed, EMBASE, the Cochrane Library, CNKI, etc.) and supplemented these searches with manual literature collection to ensure comprehensive information coverage. During the literature screening and evaluation phase, strict adherence to the predetermined inclusion and exclusion criteria was maintained to guarantee the high quality of the included studies. Further detailed quality assessments, data extraction, and analysis of the selected literature were conducted, with a focus on exploring the construction strategies of risk prediction models, the selection of key variables, the evaluation indicators of model performance, and the validation methods.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>By comparing and analysing the differences among studies in terms of methodology, model effectiveness, and practical application potential, this study summarized the development trends of diabetic foot risk prediction models and anticipated future research directions. These findings indicate that with the assistance of advanced diabetic foot risk prediction models, potential risk factors can be identified and addressed early on, thereby effectively reducing the incidence of diabetic foot and significantly improving patients\u2019 quality of life.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>This study revealed that diabetic foot risk prediction models have significant effects on accurately identifying risk factors and guiding early interventions, serving as effective tools to reduce the incidence of diabetic foot. Through early identification and intervention, the prognosis and quality of life of patients can be significantly improved, providing important references and guidance for the field of public health.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s00592-025-02505-3","type":"journal-article","created":{"date-parts":[[2025,4,19]],"date-time":"2025-04-19T02:33:08Z","timestamp":1745029988000},"page":"2095-2108","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Research progress on risk prediction models for the diabetic foot"],"prefix":"10.1007","volume":"62","author":[{"given":"Haixia","family":"Qi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tao","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lijie","family":"Hou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qi","family":"LI","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruiping","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4066-7278","authenticated-orcid":false,"given":"Lihua","family":"Ma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,4,19]]},"reference":[{"issue":"4","key":"2505_CR1","doi-asserted-by":"publisher","first-page":"542","DOI":"10.3390\/biom12040542","volume":"12","author":"M Khalid","year":"2022","unstructured":"Khalid M, Petroianu G, Adem A (2022) Advanced glycation end products and diabetes mellitus: mechanisms and perspectives. 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