{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,29]],"date-time":"2026-10-29T17:37:20Z","timestamp":1793295440720,"version":"4.5.0"},"reference-count":36,"publisher":"Springer Science and Business Media LLC","license":[{"start":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T00:00:00Z","timestamp":1790121600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T00:00:00Z","timestamp":1790121600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82201216"],"award-info":[{"award-number":["82201216"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82301212"],"award-info":[{"award-number":["82301212"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Lumitin Vision to Brightness Research Funding for the Young and Middle-aged Ophthalmologists","award":["BCF-KH-YK-20221123-11"],"award-info":[{"award-number":["BCF-KH-YK-20221123-11"]}]},{"name":"Shanghai Hospital Development Centre Foundation","award":["SHDC12023116"],"award-info":[{"award-number":["SHDC12023116"]}],"id":[{"id":"https:\/\/ror.org\/02zrtve16","id-type":"ROR","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Acta Diabetol"],"DOI":"10.1007\/s00592-026-02799-x","type":"journal-article","created":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T05:46:05Z","timestamp":1790142365000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Association between peripheral blood biomarkers and diabetic macular edema"],"prefix":"10.1007","author":[{"ORCID":"https:\/\/orcid.org\/0009-0001-4039-3692","authenticated-orcid":false,"given":"Ruowen","family":"Gong","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruyi","family":"Han","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Han","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meidie","family":"Pan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xin","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gezhi","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6406-4722","authenticated-orcid":false,"given":"Wei","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,9,23]]},"reference":[{"issue":"11","key":"2799_CR1","doi-asserted-by":"publisher","first-page":"1580","DOI":"10.1016\/j.ophtha.2021.04.027","volume":"128","author":"ZL Teo","year":"2021","unstructured":"Teo ZL, Tham YC, Yu M, Chee ML, Rim TH, Cheung N, Bikbov MM, Wang YX, Tang Y, Lu Y, Wong IY, Ting DSW, Tan GSW, Jonas JB, Sabanayagam C, Wong TY, Cheng CY (2021) Global Prevalence of Diabetic Retinopathy and Projection of Burden through 2045: Systematic Review and Meta-analysis. Ophthalmology 128(11):1580\u20131591. https:\/\/doi.org\/10.1016\/j.ophtha.2021.04.027","journal-title":"Ophthalmology"},{"issue":"5","key":"2799_CR2","doi-asserted-by":"publisher","first-page":"1383","DOI":"10.1007\/s40123-024-00925-y","volume":"13","author":"G Panozzo","year":"2024","unstructured":"Panozzo G, Cicinelli MV, Dalla Mura G, Giannarelli D, Vadala M, Bonfiglio V, Bellisario G, Bandello F, Group ES (2024) Enhancing Diabetic Macular Edema Treatment Outcomes: Exploring the ESASO Classification and Structural OCT Biomarkers. Ophthalmol Ther 13(5):1383\u20131398. https:\/\/doi.org\/10.1007\/s40123-024-00925-y","journal-title":"Ophthalmol Ther"},{"issue":"1","key":"2799_CR3","doi-asserted-by":"publisher","first-page":"8","DOI":"10.1177\/1120672119880394","volume":"30","author":"G Panozzo","year":"2020","unstructured":"Panozzo G, Cicinelli MV, Augustin AJ, Battaglia Parodi M, Cunha-Vaz J, Guarnaccia G, Kodjikian L, Jampol LM, Junemann A, Lanzetta P, Lowenstein A, Midena E, Navarro R, Querques G, Ricci F, Schmidt-Erfurth U, Silva RMD, Sivaprasad S, Varano M, Virgili G, Bandello F (2020) An optical coherence tomography-based grading of diabetic maculopathy proposed by an international expert panel: The European School for Advanced Studies in Ophthalmology classification. Eur J Ophthalmol 30(1):8\u201318. https:\/\/doi.org\/10.1177\/1120672119880394","journal-title":"Eur J Ophthalmol"},{"key":"2799_CR4","doi-asserted-by":"publisher","first-page":"101220","DOI":"10.1016\/j.preteyeres.2023.101220","volume":"98","author":"SK Szeto","year":"2024","unstructured":"Szeto SK, Lai TY, Vujosevic S, Sun JK, Sadda SR, Tan G, Sivaprasad S, Wong TY, Cheung CY (2024) Optical coherence tomography in the management of diabetic macular oedema. Prog Retin Eye Res 98:101220. https:\/\/doi.org\/10.1016\/j.preteyeres.2023.101220","journal-title":"Prog Retin Eye Res"},{"issue":"1","key":"2799_CR5","doi-asserted-by":"publisher","first-page":"232","DOI":"10.1186\/s12886-023-02973-7","volume":"23","author":"L Yu","year":"2023","unstructured":"Yu L, Hao X, Cheng J, Ling Y, Ren H, Mo B, Liu W (2023) Predictive effect of TCED-HFV grading and imaging biomarkers on anti-VEGF therapy in diabetic macular edema. BMC Ophthalmol 23(1):232. https:\/\/doi.org\/10.1186\/s12886-023-02973-7","journal-title":"BMC Ophthalmol"},{"key":"2799_CR6","doi-asserted-by":"publisher","first-page":"6426003","DOI":"10.1155\/2021\/6426003","volume":"2021","author":"E Dimitriou","year":"2021","unstructured":"Dimitriou E, Sergentanis TN, Lambadiari V, Theodossiadis G, Theodossiadis P, Chatziralli I (2021) Correlation between Imaging Morphological Findings and Laboratory Biomarkers in Patients with Diabetic Macular Edema. J Diabetes Res 2021:6426003. https:\/\/doi.org\/10.1155\/2021\/6426003","journal-title":"J Diabetes Res"},{"issue":"1","key":"2799_CR7","doi-asserted-by":"publisher","first-page":"447","DOI":"10.1007\/s10792-024-03372-7","volume":"44","author":"W Liao","year":"2024","unstructured":"Liao W, Liu F, Liu W, Xiao C (2024) Serum inflammation biomarkers level in cystoid and diffuse diabetic macular edema. Int Ophthalmol 44(1):447. https:\/\/doi.org\/10.1007\/s10792-024-03372-7","journal-title":"Int Ophthalmol"},{"issue":"6","key":"2799_CR8","doi-asserted-by":"publisher","first-page":"3637","DOI":"10.1177\/11206721221083465","volume":"32","author":"K Ozata Gundogdu","year":"2022","unstructured":"Ozata Gundogdu K, Dogan E, Celik E, Alagoz G (2022) Serum inflammatory marker levels in serous macular detachment secondary to diabetic macular edema. Eur J Ophthalmol 32(6):3637\u20133643. https:\/\/doi.org\/10.1177\/11206721221083465","journal-title":"Eur J Ophthalmol"},{"key":"2799_CR9","doi-asserted-by":"publisher","unstructured":"Lin C, Ye W, Wu S, Huang Z (2025) Blood Cell-Derived Inflammatory Indices in Diabetic Macular Edema: Clinical Significance and Prognostic Relevance. Biomedicines 13(12). https:\/\/doi.org\/10.3390\/biomedicines13122979","DOI":"10.3390\/biomedicines13122979"},{"key":"2799_CR10","doi-asserted-by":"publisher","unstructured":"Harley O, Amelia YS, Gustianty E, Soetedjo NNM, Kartasasmita AS (2026) Association of systemic inflammatory indices and body mass index with diabetic macular edema in non-proliferative diabetic retinopathy. BMC Ophthalmol 26(1). https:\/\/doi.org\/10.1186\/s12886-026-04906-6","DOI":"10.1186\/s12886-026-04906-6"},{"key":"2799_CR11","doi-asserted-by":"publisher","first-page":"1828501","DOI":"10.3389\/fendo.2026.1828501","volume":"17","author":"Y Yang","year":"2026","unstructured":"Yang Y, Zhu Y, Feng D, Wang X (2026) Lymphocyte-to-high-density lipoprotein ratio is negatively associated with diabetic macular edema in type 2 diabetic patients. Front Endocrinol (Lausanne) 17:1828501. https:\/\/doi.org\/10.3389\/fendo.2026.1828501","journal-title":"Front Endocrinol (Lausanne)"},{"issue":"5 Suppl","key":"2799_CR12","first-page":"823","volume":"98","author":"Fundus photographic risk factors for progression of diabetic retinopathy","year":"1991","unstructured":"Fundus photographic risk factors for progression of diabetic retinopathy (1991) ETDRS report number 12. Early Treatment Diabetic Retinopathy Study Research Group. Ophthalmology 98(5 Suppl):823\u2013833","journal-title":"Ophthalmology"},{"issue":"1","key":"2799_CR13","doi-asserted-by":"publisher","first-page":"96","DOI":"10.1159\/000535199","volume":"67","author":"C Yanxia","year":"2024","unstructured":"Yanxia C, Xiongyi Y, Min F, Xiaoyun K (2024) Optical Coherence Tomography-Based Grading of Diabetic Macular Edema Is Associated with Systemic Inflammatory Indices and Imaging Biomarkers. Ophthalmic Res 67(1):96\u2013106. https:\/\/doi.org\/10.1159\/000535199","journal-title":"Ophthalmic Res"},{"issue":"9","key":"2799_CR14","doi-asserted-by":"publisher","first-page":"2887","DOI":"10.21037\/apm-22-962","volume":"11","author":"Y Zhu","year":"2022","unstructured":"Zhu Y, Xu M, Li J, Li J, Li L, Zhou Y, Song Y, Cai Q (2022) Peripheral white blood cell subtypes and the development\/progression of diabetic macular edema in type 2 diabetic patients: a comparative study. Ann Palliat Med 11(9):2887\u20132896. https:\/\/doi.org\/10.21037\/apm-22-962","journal-title":"Ann Palliat Med"},{"key":"2799_CR15","doi-asserted-by":"publisher","first-page":"237","DOI":"10.2147\/VHRM.S43211","volume":"9","author":"ZS Wang","year":"2013","unstructured":"Wang ZS, Song ZC, Bai JH, Li F, Wu T, Qi J, Hu J (2013) Red blood cell count as an indicator of microvascular complications in Chinese patients with type 2 diabetes mellitus. Vasc Health Risk Manag 9:237\u2013243. https:\/\/doi.org\/10.2147\/VHRM.S43211","journal-title":"Vasc Health Risk Manag"},{"key":"2799_CR16","doi-asserted-by":"publisher","first-page":"6656062","DOI":"10.1155\/2021\/6656062","volume":"2021","author":"Y Wang","year":"2021","unstructured":"Wang Y, Yang P, Yan Z, Liu Z, Ma Q, Zhang Z, Wang Y, Su Y (2021) The Relationship between Erythrocytes and Diabetes Mellitus. J Diabetes Res 2021:6656062. https:\/\/doi.org\/10.1155\/2021\/6656062","journal-title":"J Diabetes Res"},{"issue":"3","key":"2799_CR17","doi-asserted-by":"publisher","first-page":"327","DOI":"10.3390\/pathophysiology30030026","volume":"30","author":"A Williams","year":"2023","unstructured":"Williams A, Bissinger R, Shamaa H, Patel S, Bourne L, Artunc F, Qadri SM (2023) Pathophysiology of Red Blood Cell Dysfunction in Diabetes and Its Complications. Pathophysiology 30(3):327\u2013345. https:\/\/doi.org\/10.3390\/pathophysiology30030026","journal-title":"Pathophysiology"},{"key":"2799_CR18","doi-asserted-by":"publisher","first-page":"100344","DOI":"10.1016\/j.metop.2024.100344","volume":"25","author":"C Antoniadou","year":"2025","unstructured":"Antoniadou C, Gavriilidis E, Ritis K, Tsilingiris D (2025) Anemia in diabetes mellitus: Pathogenetic aspects and the value of early erythropoietin therapy. Metabol Open 25:100344. https:\/\/doi.org\/10.1016\/j.metop.2024.100344","journal-title":"Metabol Open"},{"key":"2799_CR19","doi-asserted-by":"publisher","first-page":"20","DOI":"10.1016\/j.preteyeres.2017.10.006","volume":"63","author":"A Daruich","year":"2018","unstructured":"Daruich A, Matet A, Moulin A, Kowalczuk L, Nicolas M, Sellam A, Rothschild PR, Omri S, Gelize E, Jonet L, Delaunay K, De Kozak Y, Berdugo M, Zhao M, Crisanti P, Behar-Cohen F (2018) Mechanisms of macular edema: Beyond the surface. Prog Retin Eye Res 63:20\u201368. https:\/\/doi.org\/10.1016\/j.preteyeres.2017.10.006","journal-title":"Prog Retin Eye Res"},{"key":"2799_CR20","doi-asserted-by":"publisher","unstructured":"Zhang J, Zhang J, Zhang C, Zhang J, Gu L, Luo D, Qiu Q (2022) Diabetic Macular Edema: Current Understanding, Molecular Mechanisms and Therapeutic Implications. Cells 11(21). https:\/\/doi.org\/10.3390\/cells11213362","DOI":"10.3390\/cells11213362"},{"issue":"7","key":"2799_CR21","doi-asserted-by":"publisher","first-page":"2834","DOI":"10.4049\/jimmunol.1601281","volume":"198","author":"M Chimen","year":"2017","unstructured":"Chimen M, Yates CM, McGettrick HM, Ward LS, Harrison MJ, Apta B, Dib LH, Imhof BA, Harrison P, Nash GB, Rainger GE (2017) Monocyte Subsets Coregulate Inflammatory Responses by Integrated Signaling through TNF and IL-6 at the Endothelial Cell Interface. J Immunol 198(7):2834\u20132843. https:\/\/doi.org\/10.4049\/jimmunol.1601281","journal-title":"J Immunol"},{"key":"2799_CR22","doi-asserted-by":"publisher","unstructured":"Binet F, Cagnone G, Crespo-Garcia S, Hata M, Neault M, Dejda A, Wilson AM, Buscarlet M, Mawambo GT, Howard JP, Diaz-Marin R, Parinot C, Guber V, Pilon F, Juneau R, Laflamme R, Sawchyn C, Boulay K, Leclerc S, Abu-Thuraia A, Cote JF, Andelfinger G, Rezende FA, Sennlaub F, Joyal JS, Mallette FA, Sapieha P (2020) Neutrophil extracellular traps target senescent vasculature for tissue remodeling in retinopathy. Science 369(6506). https:\/\/doi.org\/10.1126\/science.aay5356","DOI":"10.1126\/science.aay5356"},{"key":"2799_CR23","doi-asserted-by":"publisher","first-page":"1190239","DOI":"10.3389\/fendo.2023.1190239","volume":"14","author":"C Lei","year":"2023","unstructured":"Lei C, Gu J, Liu L, Zhang K, Zhang M (2023) The correlation between peripheral complete blood count parameters and diabetic macular edema in proliferative diabetic retinopathy patients: a cross-sectional study. Front Endocrinol (Lausanne) 14:1190239. https:\/\/doi.org\/10.3389\/fendo.2023.1190239","journal-title":"Front Endocrinol (Lausanne)"},{"issue":"5","key":"2799_CR24","doi-asserted-by":"publisher","first-page":"442","DOI":"10.2174\/1573399815666191024085838","volume":"16","author":"A Berbudi","year":"2020","unstructured":"Berbudi A, Rahmadika N, Tjahjadi AI, Ruslami R (2020) Type 2 Diabetes and its Impact on the Immune System. Curr Diabetes Rev 16(5):442\u2013449. https:\/\/doi.org\/10.2174\/1573399815666191024085838","journal-title":"Curr Diabetes Rev"},{"issue":"1","key":"2799_CR25","doi-asserted-by":"publisher","first-page":"23","DOI":"10.1186\/s12883-019-1245-2","volume":"19","author":"CC Hemond","year":"2019","unstructured":"Hemond CC, Glanz BI, Bakshi R, Chitnis T, Healy BC (2019) The neutrophil-to-lymphocyte and monocyte-to-lymphocyte ratios are independently associated with neurological disability and brain atrophy in multiple sclerosis. BMC Neurol 19(1):23. https:\/\/doi.org\/10.1186\/s12883-019-1245-2","journal-title":"BMC Neurol"},{"issue":"2","key":"2799_CR26","doi-asserted-by":"publisher","first-page":"e70488","DOI":"10.1002\/hsr2.70488","volume":"8","author":"M Aghaei","year":"2025","unstructured":"Aghaei M, Bahreiny SS, Zayeri ZD, Davari N, Abolhasani MM, Saki N (2025) Evaluation of Complete Blood Count Parameters in Patients With Diabetes Mellitus: A Systematic Review. Health Sci Rep 8(2):e70488. https:\/\/doi.org\/10.1002\/hsr2.70488","journal-title":"Health Sci Rep"},{"issue":"4","key":"2799_CR27","doi-asserted-by":"publisher","first-page":"901","DOI":"10.1080\/09273948.2020.1849739","volume":"30","author":"D Yalinbas Yeter","year":"2022","unstructured":"Yalinbas Yeter D, Eroglu S, Sariakcali B, Bozali E, Vural Ozec A, Erdogan H (2022) The Usefulness of Monocyte-to-High Density Lipoprotein and Neutrophil-to-Lymphocyte Ratio in Diabetic Macular Edema Prediction and Early anti-VEGF Treatment Response. Ocul Immunol Inflamm 30(4):901\u2013906. https:\/\/doi.org\/10.1080\/09273948.2020.1849739","journal-title":"Ocul Immunol Inflamm"},{"issue":"29","key":"2799_CR28","doi-asserted-by":"publisher","first-page":"e16510","DOI":"10.1097\/MD.0000000000016510","volume":"98","author":"S Ji","year":"2019","unstructured":"Ji S, Ning X, Zhang B, Shi H, Liu Z, Zhang J (2019) Platelet distribution width, platelet count, and plateletcrit in diabetic retinopathy: A systematic review and meta-analysis of PRISMA guidelines. Med (Baltim) 98(29):e16510. https:\/\/doi.org\/10.1097\/MD.0000000000016510","journal-title":"Med (Baltim)"},{"key":"2799_CR29","doi-asserted-by":"publisher","first-page":"25","DOI":"10.1186\/s13098-019-0420-3","volume":"11","author":"S Ji","year":"2019","unstructured":"Ji S, Zhang J, Fan X, Wang X, Ning X, Zhang B, Shi H, Yan H (2019) The relationship between mean platelet volume and diabetic retinopathy: a systematic review and meta-analysis. Diabetol Metab Syndr 11:25. https:\/\/doi.org\/10.1186\/s13098-019-0420-3","journal-title":"Diabetol Metab Syndr"},{"issue":"1","key":"2799_CR30","doi-asserted-by":"publisher","first-page":"25","DOI":"10.5482\/HAMO-14-09-0039","volume":"35","author":"K Hess","year":"2015","unstructured":"Hess K (2015) The vulnerable blood. Coagulation and clot structure in diabetes mellitus. Hamostaseologie 35(1):25\u201333. https:\/\/doi.org\/10.5482\/HAMO-14-09-0039","journal-title":"Hamostaseologie"},{"issue":"1","key":"2799_CR31","doi-asserted-by":"publisher","first-page":"47","DOI":"10.2174\/138161211795049804","volume":"17","author":"AY Gasparyan","year":"2011","unstructured":"Gasparyan AY, Ayvazyan L, Mikhailidis DP, Kitas GD (2011) Mean platelet volume: a link between thrombosis and inflammation? Curr Pharm Des 17(1):47\u201358. https:\/\/doi.org\/10.2174\/138161211795049804","journal-title":"Curr Pharm Des"},{"issue":"6","key":"2799_CR32","doi-asserted-by":"publisher","first-page":"659","DOI":"10.1055\/s-0035-1556731","volume":"41","author":"N Murugesan","year":"2015","unstructured":"Murugesan N, Ustunkaya T, Feener EP (2015) Thrombosis and Hemorrhage in Diabetic Retinopathy: A Perspective from an Inflammatory Standpoint. Semin Thromb Hemost 41(6):659\u2013664. https:\/\/doi.org\/10.1055\/s-0035-1556731","journal-title":"Semin Thromb Hemost"},{"issue":"9","key":"2799_CR33","doi-asserted-by":"publisher","first-page":"1820","DOI":"10.1016\/j.ophtha.2015.05.011","volume":"122","author":"R Das","year":"2015","unstructured":"Das R, Kerr R, Chakravarthy U, Hogg RE (2015) Dyslipidemia and Diabetic Macular Edema: A Systematic Review and Meta-Analysis. Ophthalmology 122(9):1820\u20131827. https:\/\/doi.org\/10.1016\/j.ophtha.2015.05.011","journal-title":"Ophthalmology"},{"issue":"7","key":"2799_CR34","doi-asserted-by":"publisher","first-page":"e12649","DOI":"10.1111\/micc.12649","volume":"27","author":"JKS Tan","year":"2020","unstructured":"Tan JKS, Wei X, Wong PA, Fang J, Kim S, Agrawal R (2020) Altered red blood cell deformability-A novel hypothesis for retinal microangiopathy in diabetic retinopathy. Microcirculation 27(7):e12649. https:\/\/doi.org\/10.1111\/micc.12649","journal-title":"Microcirculation"},{"issue":"2","key":"2799_CR35","doi-asserted-by":"publisher","first-page":"310","DOI":"10.1016\/j.ajo.2010.08.022","volume":"151","author":"T Murakami","year":"2011","unstructured":"Murakami T, Nishijima K, Sakamoto A, Ota M, Horii T, Yoshimura N (2011) Association of pathomorphology, photoreceptor status, and retinal thickness with visual acuity in diabetic retinopathy. Am J Ophthalmol 151(2):310\u2013317. https:\/\/doi.org\/10.1016\/j.ajo.2010.08.022","journal-title":"Am J Ophthalmol"},{"issue":"11","key":"2799_CR36","doi-asserted-by":"publisher","first-page":"1309","DOI":"10.1001\/jamaophthalmol.2014.2350","volume":"132","author":"JK Sun","year":"2014","unstructured":"Sun JK, Lin MM, Lammer J, Prager S, Sarangi R, Silva PS, Aiello LP (2014) Disorganization of the retinal inner layers as a predictor of visual acuity in eyes with center-involved diabetic macular edema. JAMA Ophthalmol 132(11):1309\u20131316. https:\/\/doi.org\/10.1001\/jamaophthalmol.2014.2350","journal-title":"JAMA Ophthalmol"}],"container-title":["Acta Diabetologica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00592-026-02799-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00592-026-02799-x","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00592-026-02799-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,29]],"date-time":"2026-10-29T17:02:51Z","timestamp":1793293371000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00592-026-02799-x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9,23]]},"references-count":36,"alternative-id":["2799"],"URL":"https:\/\/doi.org\/10.1007\/s00592-026-02799-x","relation":{},"ISSN":["1432-5233"],"issn-type":[{"value":"1432-5233","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,9,23]]},"assertion":[{"value":"3 June 2026","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"1 September 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"23 September 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"27 October 2026","order":5,"name":"change_date","label":"Change Date","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"Update","order":6,"name":"change_type","label":"Change Type","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The original online version of this article was revised: due to author list was incorrect in the article.","order":7,"name":"change_details","label":"Change Details","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The authors declare no conflicts of interest.","order":1,"name":"Ethics","label":"Conflict of interest","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The study was approved by the Ethics Committee of the Eye and ENT Hospital of Fudan University (approval number: 2020043). The study adhered to the tenets of the Declaration of Helsinki.","order":2,"name":"Ethics","label":"Research involving human participants","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Written informed consent was obtained from all individual participants included in the study.","order":3,"name":"Ethics","label":"Informed consent","group":{"name":"EthicsHeading","label":"Declarations"}}]}}