{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,14]],"date-time":"2026-09-14T20:56:38Z","timestamp":1789419398762,"version":"build-2803163510"},"reference-count":35,"publisher":"Springer Science and Business Media LLC","issue":"9","license":[{"start":{"date-parts":[[2021,2,20]],"date-time":"2021-02-20T00:00:00Z","timestamp":1613779200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2021,2,20]],"date-time":"2021-02-20T00:00:00Z","timestamp":1613779200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Surg Today"],"published-print":{"date-parts":[[2021,9]]},"DOI":"10.1007\/s00595-021-02247-z","type":"journal-article","created":{"date-parts":[[2021,2,20]],"date-time":"2021-02-20T14:45:07Z","timestamp":1613832307000},"page":"1446-1455","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Optimal treatment and complications of patients with the perforated upper gastrointestinal tract"],"prefix":"10.1007","volume":"51","author":[{"given":"Takahito","family":"Sugase","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Toshiya","family":"Michiura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shoichiro","family":"Urabe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kazuki","family":"Sasaki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nobuyasu","family":"Hayashi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kazuo","family":"Yamabe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2021,2,20]]},"reference":[{"key":"2247_CR1","doi-asserted-by":"publisher","first-page":"613","DOI":"10.1016\/S0140-6736(16)32404-7","volume":"390","author":"A Lanas","year":"2017","unstructured":"Lanas A, Chan FKL. Peptic ulcer disease. Lancet. 2017;390:613\u201324.","journal-title":"Lancet"},{"key":"2247_CR2","doi-asserted-by":"publisher","first-page":"1288","DOI":"10.1016\/S0140-6736(15)00276-7","volume":"386","author":"K S\u00f8reide","year":"2015","unstructured":"S\u00f8reide K, Thorsen K, Harrison EM, Bingener J, M\u00f8ller MH, Ohene-Yeboah M, et al. Perforated peptic ulcer. Lancet. 2015;386:1288\u201398.","journal-title":"Lancet"},{"key":"2247_CR3","doi-asserted-by":"publisher","first-page":"802","DOI":"10.1002\/bjs.7429","volume":"98","author":"MH M\u00f8ller","year":"2011","unstructured":"M\u00f8ller MH, Adamsen S, Thomsen RW, M\u00f8ller AM, Peptic Ulcer Perforation (PULP) trial group. Multicentre trial of a perioperative protocol to reduce mortality in patients with peptic ulcer perforation. Br J Surg. 2011;98:802\u201310.","journal-title":"Br J Surg."},{"key":"2247_CR4","doi-asserted-by":"publisher","first-page":"222","DOI":"10.17305\/bjbms.2016.1020","volume":"16","author":"N Ignjatovic","year":"2016","unstructured":"Ignjatovic N, Stojanov D, Djordjevic M, Ignjatovic J, Benedeto Stojanov D, Milojkovic B. Perforation of gastric cancer\u2014What should the surgeon do? Bosn J Basic Med Sci. 2016;16:222\u20136.","journal-title":"Bosn J Basic Med Sci"},{"key":"2247_CR5","doi-asserted-by":"publisher","first-page":"e51","DOI":"10.1002\/bjs.9368","volume":"101","author":"K S\u00f8reide","year":"2014","unstructured":"S\u00f8reide K, Thorsen K, S\u00f8reide JA. Strategies to improve the outcome of emergency surgery for perforated peptic ulcer. Br J Surg. 2014;101:e51\u201364.","journal-title":"Br J Surg"},{"key":"2247_CR6","doi-asserted-by":"publisher","first-page":"1329","DOI":"10.1007\/s11605-011-1482-1","volume":"15","author":"K Thorsen","year":"2011","unstructured":"Thorsen K, Glomsaker TB, von Meer A, S\u00f8reide K, S\u00f8reide JA. Trends in diagnosis and surgical management of patients with perforated peptic ulcer. J Gastrointest Surg. 2011;15:1329\u201335.","journal-title":"J Gastrointest Surg"},{"key":"2247_CR7","doi-asserted-by":"publisher","first-page":"283","DOI":"10.2147\/CEG.S25501","volume":"4","author":"C Suriya","year":"2011","unstructured":"Suriya C, Kasatpibal N, Kunaviktikul W, Kayee T. Diagnostic indicators for peptic ulcer perforation at a tertiary care hospital in Thailand. Clin Exp Gastroenterol. 2011;4:283\u20139.","journal-title":"Clin Exp Gastroenterol"},{"key":"2247_CR8","doi-asserted-by":"publisher","first-page":"581","DOI":"10.1055\/s-2006-925313","volume":"38","author":"CH Lim","year":"2006","unstructured":"Lim CH, Vani D, Shah SG, Everett SM, Rembacken BJ. The outcome of suspected upper gastrointestinal bleeding with 24-hour access to upper gastrointestinal endoscopy: a prospective cohort study. Endoscopy. 2006;38:581\u20135.","journal-title":"Endoscopy"},{"key":"2247_CR9","doi-asserted-by":"publisher","first-page":"161","DOI":"10.1159\/000264653","volume":"27","author":"MJ Bertleff","year":"2010","unstructured":"Bertleff MJ, Lange JF. Perforated peptic ulcer disease: a review of history and treatment. Dig Surg. 2010;27:161\u20139.","journal-title":"Dig Surg"},{"key":"2247_CR10","doi-asserted-by":"publisher","first-page":"30","DOI":"10.1016\/j.ejrad.2003.11.012","volume":"50","author":"R Grassi","year":"2004","unstructured":"Grassi R, Romano S, Pinto A, Romano L. Gastro-duodenal perforations: conventional plain film, US and CT findings in 166 consecutive patients. Eur J Radiol. 2004;50:30\u20136.","journal-title":"Eur J Radiol"},{"key":"2247_CR11","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1186\/s13017-019-0283-9","volume":"15","author":"A Tarasconi","year":"2020","unstructured":"Tarasconi A, Coccolini F, Biffl WL, Tomasoni M, Ansaloni L, Picetti E, et al. Perforated and bleeding peptic ulcer: WSES guidelines. World J Emerg Surg. 2020;15:3.","journal-title":"World J Emerg Surg"},{"key":"2247_CR12","doi-asserted-by":"publisher","first-page":"177","DOI":"10.1007\/s00535-016-1166-4","volume":"51","author":"K Satoh","year":"2016","unstructured":"Satoh K, Yoshino J, Akamatsu T, Itoh T, Kato M, Kamada T, et al. Evidence-based clinical practice guidelines for peptic ulcer disease 2015. J Gastroenterol. 2016;51:177\u201394.","journal-title":"J Gastroenterol"},{"key":"2247_CR13","doi-asserted-by":"publisher","first-page":"1049","DOI":"10.1136\/bmj.39493.646875.AE","volume":"336","author":"GH Guyatt","year":"2008","unstructured":"Guyatt GH, Oxman AD, Kunz R, Falck-Ytter Y, Vist GE, Liberati A, et al. Going from evidence to recommendations. BMJ. 2008;336:1049\u201351.","journal-title":"BMJ"},{"key":"2247_CR14","doi-asserted-by":"publisher","first-page":"924","DOI":"10.1136\/bmj.39489.470347.AD","volume":"336","author":"GH Guyatt","year":"2008","unstructured":"Guyatt GH, Oxman AD, Vist GE, Kunz R, Falck-Ytter Y, Alonso-Coello P, et al. GRADE: an emerging consensus on rating quality of evidence and strength of recommendations. BMJ. 2008;336:924\u20136.","journal-title":"BMJ"},{"key":"2247_CR15","doi-asserted-by":"publisher","first-page":"1","DOI":"10.4240\/wjgs.v9.i1.1","volume":"9","author":"KT Chung","year":"2017","unstructured":"Chung KT, Shelat VG. Perforated peptic ulcer - an update. World J Gastrointest Surg. 2017;9:1\u201312.","journal-title":"World J Gastrointest Surg"},{"key":"2247_CR16","doi-asserted-by":"publisher","first-page":"970","DOI":"10.1056\/NEJM198904133201504","volume":"320","author":"TJ Crofts","year":"1989","unstructured":"Crofts TJ, Park KG, Steele RJ, Chung SS, Li AK. A randomized trial of nonoperative treatment for perforated peptic ulcer. N Engl J Med. 1989;320:970\u20133.","journal-title":"N Engl J Med"},{"key":"2247_CR17","doi-asserted-by":"publisher","first-page":"1045","DOI":"10.1002\/bjs.9175","volume":"100","author":"DL Buck","year":"2013","unstructured":"Buck DL, Vester-Andersen M, M\u00f8ller MH, Danish Clinical Register of Emergency Surgery. Surgical delay is a critical determinant of survival in perforated peptic ulcer. Br J Surg. 2013;100:1045\u20139.","journal-title":"Br J Surg"},{"key":"2247_CR18","doi-asserted-by":"publisher","first-page":"785","DOI":"10.3109\/00365521003783320","volume":"45","author":"MH M\u00f8ller","year":"2010","unstructured":"M\u00f8ller MH, Adamsen S, Thomsen RW, M\u00f8ller AM. Preoperative prognostic factors for mortality in peptic ulcer perforation: a systematic review. Scand J Gastroenterol. 2010;45:785\u2013805.","journal-title":"Scand J Gastroenterol"},{"key":"2247_CR19","doi-asserted-by":"publisher","first-page":"801","DOI":"10.1001\/jama.2016.0287","volume":"315","author":"M Singer","year":"2016","unstructured":"Singer M, Deutschman CS, Seymour CW, Shankar-Hari M, Annane D, Bauer M, et al. The third international consensus definitions for sepsis and septic shock (Sepsis-3). JAMA. 2016;315:801\u201310.","journal-title":"JAMA"},{"key":"2247_CR20","doi-asserted-by":"publisher","first-page":"19","DOI":"10.1186\/1477-7819-4-19","volume":"4","author":"F Roviello","year":"2006","unstructured":"Roviello F, Rossi S, Marrelli D, De Manzoni G, Pedrazzani C, Morgagni P, et al. Perforated gastric carcinoma: a report of 10 cases and review of the literature. World J Surg Oncol. 2006;4:19.","journal-title":"World J Surg Oncol"},{"issue":"91","key":"2247_CR21","doi-asserted-by":"publisher","first-page":"219","DOI":"10.1002\/jso.20307","volume":"15","author":"SC Jwo","year":"2005","unstructured":"Jwo SC, Chien RN, Chao TC, Chen HY, Lin CY. Clinicopathological features, surgical management, and disease outcome of perforated gastric cancer. J Surg Oncol. 2005;15(91):219\u201325.","journal-title":"J Surg Oncol"},{"key":"2247_CR22","doi-asserted-by":"publisher","first-page":"17","DOI":"10.1186\/1749-7922-3-17","volume":"3","author":"C Kotan","year":"2008","unstructured":"Kotan C, Sumer A, Baser M, K\u0131z\u0131ltan R, Carparlar MA. An analysis of 13 patients with perforated gastric carcinoma: a surgeon\u2019s nightmare? World J Emerg Surg. 2008;3:17.","journal-title":"World J Emerg Surg"},{"key":"2247_CR23","doi-asserted-by":"publisher","first-page":"199","DOI":"10.3892\/etm_00000032","volume":"1","author":"H Tsujimoto","year":"2010","unstructured":"Tsujimoto H, Hiraki S, Sakamoto N, Yaguchi Y, Horio T, Kumano I. Outcome after emergency surgery in patients with a free perforation caused by gastric cancer. Exp Ther Med. 2010;1:199\u2013203.","journal-title":"Exp Ther Med"},{"key":"2247_CR24","first-page":"489","volume":"52","author":"BP Kandel","year":"2013","unstructured":"Kandel BP, Singh Y, Singh KP, Khakurel M. Gastric cancer perforation: experience from a tertiary care hospital. JNMA J Nepal Med Assoc. 2013;52:489\u201393.","journal-title":"JNMA J Nepal Med Assoc"},{"key":"2247_CR25","doi-asserted-by":"publisher","first-page":"948","DOI":"10.1007\/s00268-016-3821-6","volume":"41","author":"F V\u0103rcu\u015f","year":"2017","unstructured":"V\u0103rcu\u015f F, Beuran M, Lica I, Turculet C, Cotarlet AV, Georgescu S. Laparoscopic repair for perforated peptic ulcer: a retrospective study. World J Surg. 2017;41:948\u201353.","journal-title":"World J Surg"},{"key":"2247_CR26","doi-asserted-by":"publisher","first-page":"1873","DOI":"10.1007\/s00268-011-1106-7","volume":"35","author":"HC Lo","year":"2011","unstructured":"Lo HC, Wu SC, Huang HC, Yeh CC, Huang JC, Hsieh CH. Laparoscopic simple closure alone is adequate for low risk patients with perforated peptic ulcer. World J Surg. 2011;35:1873\u20138.","journal-title":"World J Surg"},{"key":"2247_CR27","doi-asserted-by":"publisher","first-page":"615","DOI":"10.1089\/lap.2006.0195","volume":"17","author":"M Ates","year":"2007","unstructured":"Ates M, Sevil S, Bakircioglu E, Colak C. Laparoscopic repair of peptic ulcer perforation without omental patch versus conventional open repair. J Laparoendosc Adv Surg Tech A. 2007;17:615\u20139.","journal-title":"J Laparoendosc Adv Surg Tech A"},{"key":"2247_CR28","doi-asserted-by":"publisher","first-page":"15","DOI":"10.1186\/1471-2482-5-15","volume":"5","author":"S Gupta","year":"2005","unstructured":"Gupta S, Kaushik R, Sharma R, Attri A. The management of large perforations of duodenal ulcers. BMC Surg. 2005;5:15.","journal-title":"BMC Surg"},{"key":"2247_CR29","doi-asserted-by":"publisher","first-page":"134","DOI":"10.1097\/SLE.0b013e31828fa951","volume":"24","author":"SL Siow","year":"2014","unstructured":"Siow SL, Mahendran HA. Laparoscopic repair of perforated peptic ulcers: the sutured omental patch and focused sequential lavage technique. Surg Laparosc Endosc Percutan Tech. 2014;24:134\u20139.","journal-title":"Surg Laparosc Endosc Percutan Tech"},{"key":"2247_CR30","doi-asserted-by":"publisher","first-page":"417","DOI":"10.1097\/TA.0000000000001925","volume":"85","author":"R Cirocchi","year":"2018","unstructured":"Cirocchi R, Soreide K, Di Saverio S, Rossi E, Arezzo A, Zago M. Meta-analysis of perioperative outcomes of acute laparoscopic versus open repair of perforated gastroduodenal ulcers. J Trauma Acute Care Surg. 2018;85:417\u201325.","journal-title":"J Trauma Acute Care Surg"},{"key":"2247_CR31","first-page":"222","volume":"45","author":"M Bergstr\u00f6m","year":"2013","unstructured":"Bergstr\u00f6m M, Arroyo V\u00e1zquez JA, Park PO. Self-expandable metal stents as a new treatment option for perforated duodenal ulcer. Endoscopy. 2013;45:222\u20135.","journal-title":"Endoscopy"},{"key":"2247_CR32","doi-asserted-by":"publisher","first-page":"1394","DOI":"10.1007\/s00464-004-8142-4","volume":"18","author":"HA Alvarado-Aparicio","year":"2004","unstructured":"Alvarado-Aparicio HA, Moreno-Portillo M. Multimedia article: management of duodenal ulcer perforation with combined laparoscopic and endoscopic methods. Surg Endosc. 2004;18:1394.","journal-title":"Surg Endosc"},{"key":"2247_CR33","doi-asserted-by":"publisher","first-page":"991","DOI":"10.1097\/00005373-200006000-00001","volume":"48","author":"AK Malhotra","year":"2000","unstructured":"Malhotra AK, Fabian TC, Katsis SB, Gavant ML, Croce MA. Blunt bowel and mesenteric injuries: the role of screening computed tomography. J Trauma. 2000;48:991\u20131000.","journal-title":"J Trauma"},{"key":"2247_CR34","doi-asserted-by":"publisher","first-page":"329","DOI":"10.1016\/S0899-7071(03)00204-3","volume":"28","author":"KW Yeung","year":"2004","unstructured":"Yeung KW, Chang MS, Hsiao CP, Huang JF. CT evaluation of gastrointestinal tract perforation. Clin Imaging. 2004;28:329\u201333.","journal-title":"Clin Imaging"},{"key":"2247_CR35","doi-asserted-by":"publisher","first-page":"157","DOI":"10.1186\/s12939-018-0869-y","volume":"17","author":"L He","year":"2018","unstructured":"He L, Yu H, Shi L, He Y, Geng J, Wei Y, et al. Equity assessment of the distribution of CT and MRI scanners in China: a panel data analysis. Int J Equity Health. 2018;17:157.","journal-title":"Int J Equity Health"}],"container-title":["Surgery Today"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00595-021-02247-z.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00595-021-02247-z\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00595-021-02247-z.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,8,20]],"date-time":"2021-08-20T00:06:44Z","timestamp":1629418004000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00595-021-02247-z"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,2,20]]},"references-count":35,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2021,9]]}},"alternative-id":["2247"],"URL":"https:\/\/doi.org\/10.1007\/s00595-021-02247-z","relation":{},"ISSN":["0941-1291","1436-2813"],"issn-type":[{"value":"0941-1291","type":"print"},{"value":"1436-2813","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,2,20]]},"assertion":[{"value":"14 October 2020","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"2 January 2021","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"20 February 2021","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"Sugase T and the other co-authors have no conflicts of interest to declare.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}