{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,17]],"date-time":"2026-10-17T04:39:34Z","timestamp":1792211974061,"version":"4.4.0"},"reference-count":20,"publisher":"Springer Science and Business Media LLC","issue":"7","license":[{"start":{"date-parts":[[2022,11,27]],"date-time":"2022-11-27T00:00:00Z","timestamp":1669507200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2022,11,27]],"date-time":"2022-11-27T00:00:00Z","timestamp":1669507200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/100009619","name":"Japan Agency for Medical Research and Development","doi-asserted-by":"publisher","award":["JP21mk0101179"],"award-info":[{"award-number":["JP21mk0101179"]}],"id":[{"id":"10.13039\/100009619","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["JP21mk0101179"],"award-info":[{"award-number":["JP21mk0101179"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Surg Today"],"published-print":{"date-parts":[[2023,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Purpose<\/jats:title>\n                <jats:p>To compare the characteristics of reimplantation (RI) using grafts with sinuses and remodeling (RM) with\/without external suture annuloplasty using a pulsatile flow simulator.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methods<\/jats:title>\n                <jats:p>Porcine aortic roots were obtained from an abattoir, and six models of RM and RI with sinuses were prepared. External suture annuloplasty (ESA) was performed in the RM models to decrease the root diameter to 22\u00a0mm (RM-AP22) and 18\u00a0mm (RM-AP18). Valve models were tested at mean pulsatile flow and aortic pressure of 5.0 L\/min and 120\/80 (100) mmHg, respectively, at 70 beats\/min. The forward flow, regurgitation, leakage, backflow rates, valve-closing time, and mean and peak pressure gradient (p-PG) were evaluated. Root configurations were examined using micro-computed tomography (micro-CT).<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>The backflow rate was larger in the RM models than in the RI models (RI: 8.56%\u2009\u00b1\u20090.38% vs. RM: 12.64%\u2009\u00b1\u20090.79%; <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.01). The RM-AP and RI models were comparable in terms of the forward flow, regurgitation, backflow rates, p-PG, and valve-closing time. The analysis using a micro-CT showed a larger dilatation of the sinus of the Valsalva in the RM groups than in the RI group (Valsalva: RI, 26.55\u2009\u00b1\u20090.40\u00a0mm vs. RM-AP22, 31.22\u2009\u00b1\u20090.55\u00a0mm [<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.05]; RM-AP18, 31.05\u2009\u00b1\u20090.85\u00a0mm [<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.05]).<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusions<\/jats:title>\n                <jats:p>RM with ESA and RI with neo-sinuses showed comparable hemodynamics. ESA to RM reduced regurgitation.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1007\/s00595-022-02622-4","type":"journal-article","created":{"date-parts":[[2022,11,27]],"date-time":"2022-11-27T20:12:39Z","timestamp":1669579959000},"page":"845-854","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Comparison of hemodynamics and root configurations between remodeling and reimplantation methods for valve-sparing aortic root replacement: a pulsatile flow study"],"prefix":"10.1007","volume":"53","author":[{"given":"Masahiro","family":"Seki","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takashi","family":"Kunihara","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jyunpei","family":"Takada","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kenichi","family":"Sasaki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ryo","family":"Kumazawa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroshi","family":"Seki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saeko","family":"Sasuga","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hirotsugu","family":"Fukuda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mitsuo","family":"Umezu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kiyotaka","family":"Iwasaki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2022,11,27]]},"reference":[{"key":"2622_CR1","doi-asserted-by":"publisher","first-page":"1126","DOI":"10.1016\/j.athoracsur.2015.05.093","volume":"100","author":"B Arabkhani","year":"2015","unstructured":"Arabkhani B, Mookhoek A, di Centa I, Lansac E, Bekkers JA, de Lind Van Wijngaarden R, et al. 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