{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,29]],"date-time":"2026-07-29T20:35:13Z","timestamp":1785357313371,"version":"3.55.0"},"reference-count":30,"publisher":"Springer Science and Business Media LLC","issue":"12","license":[{"start":{"date-parts":[[2024,5,20]],"date-time":"2024-05-20T00:00:00Z","timestamp":1716163200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2024,5,20]],"date-time":"2024-05-20T00:00:00Z","timestamp":1716163200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Surg Today"],"published-print":{"date-parts":[[2024,12]]},"DOI":"10.1007\/s00595-024-02868-0","type":"journal-article","created":{"date-parts":[[2024,5,20]],"date-time":"2024-05-20T03:11:06Z","timestamp":1716174666000},"page":"1472-1481","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Preoperative factors associated with lateral lymph node metastasis in lower rectal cancer and the evaluation of the middle rectal artery"],"prefix":"10.1007","volume":"54","author":[{"given":"Takuya","family":"Shiraishi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroomi","family":"Ogawa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arisa","family":"Yamaguchi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuta","family":"Shibasaki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katsuya","family":"Osone","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takuhisa","family":"Okada","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Makoto","family":"Sakai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Makoto","family":"Sohda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ken","family":"Shirabe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroshi","family":"Saeki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,5,20]]},"reference":[{"key":"2868_CR1","doi-asserted-by":"publisher","first-page":"729","DOI":"10.1245\/s10434-007-9696-x","volume":"15","author":"TH Kim","year":"2008","unstructured":"Kim TH, Jeong SY, Choi DH, Kim DY, Jung KH, Moon SH, et al. Lateral lymph node metastasis is a major cause of locoregional recurrence in rectal cancer treated with preoperative chemoradiotherapy and curative resection. Ann Surg Oncol. 2008;15:729\u201337. https:\/\/doi.org\/10.1245\/s10434-007-9696-x.","journal-title":"Ann Surg Oncol"},{"key":"2868_CR2","doi-asserted-by":"publisher","first-page":"731","DOI":"10.1002\/ags3.12490","volume":"5","author":"TC Sluckin","year":"2021","unstructured":"Sluckin TC, Hazen SJA, Kusters M. From, \u201cEast vs West\u201d towards international multidisciplinary collaboration: an appraisal of lateral lymph nodes in rectal cancer. Ann Gastroenterol Surg. 2021;5:731\u20137. https:\/\/doi.org\/10.1002\/ags3.12490.","journal-title":"Ann Gastroenterol Surg"},{"key":"2868_CR3","doi-asserted-by":"publisher","first-page":"201","DOI":"10.1097\/SLA.0000000000002212","volume":"266","author":"S Fujita","year":"2017","unstructured":"Fujita S, Mizusawa J, Kanemitsu Y, Ito M, Kinugasa Y, Komori K, et al. Mesorectal excision with or without lateral lymph node dissection for clinical stage II\/III lower rectal cancer (JCOG0212): A multicenter, randomized controlled, noninferiority trial. Ann Surg. 2017;266:201\u20137. https:\/\/doi.org\/10.1097\/SLA.0000000000002212.","journal-title":"Ann Surg"},{"key":"2868_CR4","doi-asserted-by":"publisher","first-page":"1851","DOI":"10.1016\/j.ejso.2016.07.010","volume":"42","author":"S Saito","year":"2016","unstructured":"Saito S, Fujita S, Mizusawa J, Kanemitsu Y, Saito N, Kinugasa Y, et al. Male sexual dysfunction after rectal cancer surgery: results of a randomized trial comparing mesorectal excision with and without lateral lymph node dissection for patients with lower rectal cancer: Japan Clinical Oncology Group Study JCOG0212. Eur J Surg Oncol. 2016;42:1851\u20138. https:\/\/doi.org\/10.1016\/j.ejso.2016.07.010.","journal-title":"Eur J Surg Oncol"},{"key":"2868_CR5","doi-asserted-by":"publisher","first-page":"463","DOI":"10.1016\/j.ejso.2018.01.015","volume":"44","author":"M Ito","year":"2018","unstructured":"Ito M, Kobayashi A, Fujita S, Mizusawa J, Kanemitsu Y, Kinugasa Y, et al. Urinary dysfunction after rectal cancer surgery: results from a randomized trial comparing mesorectal excision with and without lateral lymph node dissection for clinical stage II or III lower rectal cancer (Japan Clinical Oncology Group Study, JCOG0212). Eur J Surg Oncol. 2018;44:463\u20138. https:\/\/doi.org\/10.1016\/j.ejso.2018.01.015.","journal-title":"Eur J Surg Oncol"},{"key":"2868_CR6","doi-asserted-by":"publisher","first-page":"520","DOI":"10.1186\/s12885-021-08278-6","volume":"21","author":"R Yukimoto","year":"2021","unstructured":"Yukimoto R, Uemura M, Tsuboyama T, Hata T, Fujino S, Ogino T, et al. Efficacy of positron emission tomography in diagnosis of lateral lymph node metastases in patients with rectal Cancer: a retrospective study. BMC Cancer. 2021;21:520. https:\/\/doi.org\/10.1186\/s12885-021-08278-6.","journal-title":"BMC Cancer"},{"key":"2868_CR7","doi-asserted-by":"publisher","first-page":"1085","DOI":"10.1007\/s00384-009-0704-4","volume":"24","author":"S Fujita","year":"2009","unstructured":"Fujita S, Yamamoto S, Akasu T, Moriya Y. Risk factors of lateral pelvic lymph node metastasis in advanced rectal cancer. Int J Colorectal Dis. 2009;24:1085\u201390. https:\/\/doi.org\/10.1007\/s00384-009-0704-4.","journal-title":"Int J Colorectal Dis"},{"key":"2868_CR8","doi-asserted-by":"publisher","first-page":"1583","DOI":"10.1007\/s00595-021-02250-4","volume":"51","author":"A Hamabe","year":"2021","unstructured":"Hamabe A, Ishii M, Onodera K, Okita K, Nishidate T, Okuya K, et al. MRI-detected extramural vascular invasion potentiates the risk for pathological metastasis to the lateral lymph nodes in rectal cancer. Surg Today. 2021;51:1583\u201393. https:\/\/doi.org\/10.1007\/s00595-021-02250-4.","journal-title":"Surg Today"},{"key":"2868_CR9","doi-asserted-by":"publisher","first-page":"1677","DOI":"10.1007\/s00384-021-03887-w","volume":"36","author":"Y Iwasa","year":"2021","unstructured":"Iwasa Y, Koyama F, Marugami N, Kuge H, Nakamoto T, Obara S, et al. The middle rectal artery detected by contrast-enhanced magnetic resonance imaging predicts lateral lymph node metastasis in lower rectal cancer. Int J Colorectal Dis. 2021;36:1677\u201384. https:\/\/doi.org\/10.1007\/s00384-021-03887-w.","journal-title":"Int J Colorectal Dis"},{"key":"2868_CR10","doi-asserted-by":"publisher","first-page":"795","DOI":"10.1002\/ags3.12590","volume":"6","author":"Y Suzuki","year":"2022","unstructured":"Suzuki Y, Sasaki T, Hasegawa H, Ikeda K, Teramura K, Tsukada Y, et al. Morphological characteristics of lateral pelvic lymph nodes in locally advanced lower rectal cancer: a retrospective study. Ann Gastroenterol Surg. 2022;6:795\u2013803. https:\/\/doi.org\/10.1002\/ags3.12590.","journal-title":"Ann Gastroenterol Surg"},{"key":"2868_CR11","doi-asserted-by":"publisher","first-page":"92","DOI":"10.1002\/ags3.12504","volume":"6","author":"S Kasai","year":"2022","unstructured":"Kasai S, Shiomi A, Kagawa H, Hino H, Manabe S, Yamaoka Y, et al. The effectiveness of machine learning in predicting lateral lymph node metastasis from lower rectal cancer: a Single Center development and validation study. Ann Gastroenterol Surg. 2022;6:92\u2013100. https:\/\/doi.org\/10.1002\/ags3.12504.","journal-title":"Ann Gastroenterol Surg"},{"key":"2868_CR12","doi-asserted-by":"publisher","first-page":"635","DOI":"10.1002\/ar.1091080402","volume":"108","author":"JB Blair","year":"1950","unstructured":"Blair JB, Holyoke EA, Best RR. A note on the lymphatics of the middle and lower rectum and anus. Anat Rec. 1950;108:635\u201344. https:\/\/doi.org\/10.1002\/ar.1091080402.","journal-title":"Anat Rec"},{"key":"2868_CR13","doi-asserted-by":"publisher","first-page":"443","DOI":"10.1111\/j.1463-1318.2009.01769.x","volume":"11","author":"S Bell","year":"2009","unstructured":"Bell S, Sasaki J, Sinclair G, Chapuis PH, Bokey EL. Understanding the anatomy of lymphatic drainage and the use of blue-dye mapping to determine the extent of lymphadenectomy in rectal cancer surgery: unresolved issues. Colorectal Dis. 2009;11:443\u20139. https:\/\/doi.org\/10.1111\/j.1463-1318.2009.01769.x.","journal-title":"Colorectal Dis"},{"key":"2868_CR14","doi-asserted-by":"publisher","first-page":"17","DOI":"10.1007\/BF01623135","volume":"13","author":"K Sato","year":"1991","unstructured":"Sato K, Sato T. The vascular and neuronal composition of the lateral ligament of the rectum and the rectosacral fascia. Surg Radiol Anat. 1991;13:17\u201322. https:\/\/doi.org\/10.1007\/BF01623135.","journal-title":"Surg Radiol Anat"},{"key":"2868_CR15","doi-asserted-by":"publisher","first-page":"517","DOI":"10.1007\/s00276-012-1068-y","volume":"35","author":"T Bilhim","year":"2013","unstructured":"Bilhim T, Pereira JA, Tinto HR, Fernandes L, Duarte M, O\u2019Neill JE, et al. Middle rectal artery: myth or reality? Retrospective study with CT angiography and digital subtraction angiography. Surg Radiol Anat. 2013;35:517\u201322. https:\/\/doi.org\/10.1007\/s00276-012-1068-y.","journal-title":"Surg Radiol Anat"},{"key":"2868_CR16","doi-asserted-by":"publisher","first-page":"487","DOI":"10.1046\/j.1365-2168.1999.01080.x","volume":"86","author":"OM Jones","year":"1999","unstructured":"Jones OM, Smeulders N, Wiseman O, Miller R. Lateral ligaments of the rectum: an anatomical study. Br J Surg. 1999;86:487\u20139. https:\/\/doi.org\/10.1046\/j.1365-2168.1999.01080.x.","journal-title":"Br J Surg"},{"key":"2868_CR17","doi-asserted-by":"publisher","unstructured":"Nano M, Dal Corso HM, Lanfranco G, Ferronato M, Hornung JP. Contribution to the surgical anatomy of the ligaments of the rectum. Dis Colon Rectum. 2000;43:1592\u20137; discussion 1597\u20138. https:\/\/doi.org\/10.1007\/BF02236746","DOI":"10.1007\/BF02236746"},{"key":"2868_CR18","doi-asserted-by":"publisher","unstructured":"Hashiguchi Y, Muro K, Saito Y, Ito Y, Ajioka Y, Hamaguchi T, et al. Japanese Society for Cancer of the Colon and Rectum (JSCCR) guidelines 2019 for the treatment of colorectal cancer. Int J Clin Oncol. 2020; https:\/\/doi.org\/10.1007\/s10147-019-01485-z","DOI":"10.1007\/s10147-019-01485-z"},{"key":"2868_CR19","doi-asserted-by":"publisher","first-page":"33","DOI":"10.1200\/JCO.18.00032","volume":"37","author":"A Ogura","year":"2019","unstructured":"Ogura A, Konishi T, Cunningham C, Garcia-Aguilar J, Iversen H, Toda S, et al. Neoadjuvant (chemo)radiotherapy with total mesorectal excision only is not sufficient to prevent lateral local recurrence in enlarged nodes: results of the multicenter lateral node study of patients with low cT3\/4 rectal cancer. J Clin Oncol. 2019;37:33\u201343. https:\/\/doi.org\/10.1200\/JCO.18.00032.","journal-title":"J Clin Oncol"},{"key":"2868_CR20","doi-asserted-by":"publisher","first-page":"14","DOI":"10.1007\/s00595-016-1359-8","volume":"47","author":"T Kiyomatsu","year":"2017","unstructured":"Kiyomatsu T, Ishihara S, Murono K, Otani K, Yasuda K, Nishikawa T, et al. Anatomy of the middle rectal artery: a review of the historical literature. Surg Today. 2017;47:14\u20139. https:\/\/doi.org\/10.1007\/s00595-016-1359-8.","journal-title":"Surg Today"},{"key":"2868_CR21","doi-asserted-by":"publisher","first-page":"336","DOI":"10.1016\/j.ejso.2018.11.016","volume":"45","author":"K Komori","year":"2019","unstructured":"Komori K, Fujita S, Mizusawa J, Kanemitsu Y, Ito M, Shiomi A, et al. Predictive factors of pathological lateral pelvic lymph node metastasis in patients without clinical lateral pelvic lymph node metastasis (clinical stage II\/III): the analysis of data from the clinical trial (JCOG0212). Eur J Surg Oncol. 2019;45:336\u201340. https:\/\/doi.org\/10.1016\/j.ejso.2018.11.016.","journal-title":"Eur J Surg Oncol"},{"key":"2868_CR22","doi-asserted-by":"publisher","first-page":"35","DOI":"10.1093\/jjco\/hyu162","volume":"45","author":"S Hatano","year":"2015","unstructured":"Hatano S, Ishida H, Ishiguro T, Kumamoto K, Ishibashi K, Mochiki E, et al. Prediction of metastasis to mesorectal, internal iliac and obturator lymph nodes according to size criteria in patients with locally advanced lower rectal cancer. Jpn J Clin Oncol. 2015;45:35\u201342. https:\/\/doi.org\/10.1093\/jjco\/hyu162.","journal-title":"Jpn J Clin Oncol"},{"key":"2868_CR23","doi-asserted-by":"publisher","first-page":"205","DOI":"10.1093\/bjs\/znaa009","volume":"108","author":"DP Schaap","year":"2021","unstructured":"Schaap DP, Boogerd LSF, Konishi T, Cunningham C, Ogura A, Garcia-Aguilar J, et al. Rectal cancer lateral lymph nodes: multicentre study of the impact of obturator and internal iliac nodes on oncological outcomes. Br J Surg. 2021;108:205\u201313. https:\/\/doi.org\/10.1093\/bjs\/znaa009.","journal-title":"Br J Surg"},{"key":"2868_CR24","doi-asserted-by":"publisher","first-page":"397","DOI":"10.1245\/ASO.2006.04.042","volume":"13","author":"SL Gearhart","year":"2006","unstructured":"Gearhart SL, Frassica D, Rosen R, Choti M, Schulick R, Wahl R. Improved staging with pretreatment positron emission tomography\/computed tomography in low rectal cancer. Ann Surg Oncol. 2006;13:397\u2013404. https:\/\/doi.org\/10.1245\/ASO.2006.04.042.","journal-title":"Ann Surg Oncol."},{"key":"2868_CR25","doi-asserted-by":"publisher","first-page":"1423","DOI":"10.1016\/j.ijrobp.2007.08.043","volume":"70","author":"MC Bassi","year":"2008","unstructured":"Bassi MC, Turri L, Sacchetti G, Loi G, Cannillo B, La Mattina P, et al. FDG-PET\/CT imaging for staging and target volume delineation in preoperative conformal radiotherapy of rectal cancer. Int J Radiat Oncol Biol Phys. 2008;70:1423\u20136. https:\/\/doi.org\/10.1016\/j.ijrobp.2007.08.043.","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"2868_CR26","doi-asserted-by":"publisher","first-page":"347","DOI":"10.1007\/s10151-018-1779-0","volume":"22","author":"S Ishihara","year":"2018","unstructured":"Ishihara S, Kawai K, Tanaka T, Kiyomatsu T, Hata K, Nozawa H, et al. Diagnostic value of FDG-PET\/CT for lateral pelvic lymph node metastasis in rectal cancer treated with preoperative chemoradiotherapy. Tech Coloproctol. 2018;22:347\u201354. https:\/\/doi.org\/10.1007\/s10151-018-1779-0.","journal-title":"Tech Coloproctol"},{"key":"2868_CR27","doi-asserted-by":"publisher","first-page":"616","DOI":"10.1016\/S1470-2045(12)70158-4","volume":"13","author":"S Fujita","year":"2012","unstructured":"Fujita S, Akasu T, Mizusawa J, Saito N, Kinugasa Y, Kanemitsu Y, et al. Postoperative morbidity and mortality after mesorectal excision with and without lateral lymph node dissection for clinical stage II or stage III lower rectal cancer (JCOG0212): results from a multicentre, randomised controlled, non-inferiority trial. Lancet Oncol. 2012;13:616\u201321. https:\/\/doi.org\/10.1016\/S1470-2045(12)70158-4.","journal-title":"Lancet Oncol"},{"key":"2868_CR28","doi-asserted-by":"publisher","first-page":"995","DOI":"10.1007\/s00268-015-3299-7","volume":"40","author":"A Ishibe","year":"2016","unstructured":"Ishibe A, Ota M, Watanabe J, Suwa Y, Suzuki S, Kanazawa A, et al. Prediction of lateral pelvic lymph-node metastasis in low rectal cancer by magnetic resonance imaging. World J Surg. 2016;40:995\u20131001. https:\/\/doi.org\/10.1007\/s00268-015-3299-7.","journal-title":"World J Surg"},{"key":"2868_CR29","doi-asserted-by":"publisher","first-page":"413","DOI":"10.1159\/000108323","volume":"24","author":"H Kawahara","year":"2007","unstructured":"Kawahara H, Nimura H, Watanabe K, Kobayashi T, Kashiwagi H, Yanaga K. Where does the first lateral pelvic lymph node receive drainage from? Dig Surg. 2007;24:413\u20137. https:\/\/doi.org\/10.1159\/000108323.","journal-title":"Dig Surg"},{"key":"2868_CR30","doi-asserted-by":"publisher","first-page":"759","DOI":"10.1007\/s10151-023-02761-x","volume":"27","author":"J Watanabe","year":"2023","unstructured":"Watanabe J, Ohya H, Sakai J, Suwa Y, Goto K, Nakagawa K, et al. Long-term outcomes of indocyanine green fluorescence imaging-guided laparoscopic lateral pelvic lymph node dissection for clinical stage II\/III middle-lower rectal cancer: a propensity score-matched cohort study. Tech Coloproctol. 2023;27:759\u201367. https:\/\/doi.org\/10.1007\/s10151-023-02761-x.","journal-title":"Tech Coloproctol"}],"container-title":["Surgery Today"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00595-024-02868-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00595-024-02868-0\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00595-024-02868-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,11,21]],"date-time":"2024-11-21T07:15:13Z","timestamp":1732173313000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00595-024-02868-0"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,5,20]]},"references-count":30,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2024,12]]}},"alternative-id":["2868"],"URL":"https:\/\/doi.org\/10.1007\/s00595-024-02868-0","relation":{},"ISSN":["0941-1291","1436-2813"],"issn-type":[{"value":"0941-1291","type":"print"},{"value":"1436-2813","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,5,20]]},"assertion":[{"value":"6 February 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"26 April 2024","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"20 May 2024","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no conflicts of Interests for this article.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}