{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,14]],"date-time":"2026-09-14T21:36:16Z","timestamp":1789421776754,"version":"build-2803163510"},"reference-count":38,"publisher":"Springer Science and Business Media LLC","issue":"8","license":[{"start":{"date-parts":[[2026,3,26]],"date-time":"2026-03-26T00:00:00Z","timestamp":1774483200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2026,3,26]],"date-time":"2026-03-26T00:00:00Z","timestamp":1774483200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Surg Today"],"published-print":{"date-parts":[[2026,8]]},"DOI":"10.1007\/s00595-026-03283-3","type":"journal-article","created":{"date-parts":[[2026,3,26]],"date-time":"2026-03-26T12:59:15Z","timestamp":1774529955000},"page":"1636-1644","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Risk factors associated with a delayed recovery of gastrointestinal motility after colon cancer surgery: an objective evaluation using radiopaque markers"],"prefix":"10.1007","volume":"56","author":[{"given":"Yasuyuki","family":"Yokoyama","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takeshi","family":"Yamada","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kay","family":"Uehara","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seiichi","family":"Shinji","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akihisa","family":"Matsuda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Goro","family":"Takahashi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takuma","family":"Iwai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Toshimitsu","family":"Miyasaka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiromichi","family":"Sonoda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroshi","family":"Yoshida","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,3,26]]},"reference":[{"key":"3283_CR1","first-page":"466","volume":"24","author":"KC Fearon","year":"2005","unstructured":"Fearon KC, Ljungqvist O, Von Meyenfeldt M, Revhaug A, Dejong CH, Lassen K, et al. Enhanced recovery after surgery: a consensus review of clinical care for patients undergoing colonic resection. Clinical nutrition (Edinburgh. Scotland). 2005;24:466\u201377.","journal-title":"Scotland)"},{"key":"3283_CR2","doi-asserted-by":"publisher","first-page":"909","DOI":"10.1097\/SLA.0b013e318268a693","volume":"257","author":"PH Chapuis","year":"2013","unstructured":"Chapuis PH, Bokey L, Keshava A, Rickard MJ, Stewart P, Young CJ, et al. Risk factors for prolonged ileus after resection of colorectal cancer: an observational study of 2400 consecutive patients. Ann Surg. 2013;257:909\u201315.","journal-title":"Ann Surg"},{"key":"3283_CR3","first-page":"367","volume":"34","author":"D Bragg","year":"2015","unstructured":"Bragg D, El-Sharkawy AM, Psaltis E, Maxwell-Armstrong CA, Lobo DN. Postoperative ileus: Recent developments in pathophysiology and management. Clinical nutrition (Edinburgh. Scotland). 2015;34:367\u201376.","journal-title":"Scotland)"},{"key":"3283_CR4","doi-asserted-by":"publisher","first-page":"189","DOI":"10.1097\/SLA.0b013e31817f2c1a","volume":"248","author":"H Kehlet","year":"2008","unstructured":"Kehlet H, Wilmore DW. Evidence-based surgical care and the evolution of fast-track surgery. Ann Surg. 2008;248:189\u201398.","journal-title":"Ann Surg"},{"key":"3283_CR5","doi-asserted-by":"publisher","first-page":"2014","DOI":"10.1016\/j.clnu.2019.10.023","volume":"39","author":"L Gianotti","year":"2020","unstructured":"Gianotti L, Sandini M, Romagnoli S, Carli F, Ljungqvist O. Enhanced recovery programs in gastrointestinal surgery: Actions to promote optimal perioperative nutritional and metabolic care. Clin Nutr. 2020;39:2014\u201324.","journal-title":"Clin Nutr"},{"key":"3283_CR6","doi-asserted-by":"publisher","first-page":"659","DOI":"10.1007\/s00268-018-4844-y","volume":"43","author":"UO Gustafsson","year":"2019","unstructured":"Gustafsson UO, Scott MJ, Hubner M, Nygren J, Demartines N, Francis N, et al. Guidelines for Perioperative Care in Elective Colorectal Surgery: Enhanced Recovery After Surgery (ERAS(\u00ae)) Society Recommendations: 2018. World J Surg. 2019;43:659\u201395.","journal-title":"World J Surg"},{"key":"3283_CR7","doi-asserted-by":"publisher","first-page":"1826","DOI":"10.1007\/s00268-022-06587-w","volume":"46","author":"R Oodit","year":"2022","unstructured":"Oodit R, Biccard BM, Panieri E, Alvarez AO, Sioson MRS, Maswime S, et al. Guidelines for Perioperative Care in Elective Abdominal and Pelvic Surgery at Primary and Secondary Hospitals in Low-Middle-Income Countries (LMIC\u2019s): Enhanced Recovery After Surgery (ERAS) Society Recommendation. World J Surg. 2022;46:1826\u201343.","journal-title":"World J Surg"},{"key":"3283_CR8","doi-asserted-by":"publisher","first-page":"638","DOI":"10.1016\/j.bja.2020.01.017","volume":"124","author":"SG Memtsoudis","year":"2020","unstructured":"Memtsoudis SG, Fiasconaro M, Soffin EM, Liu J, Wilson LA, Poeran J, et al. Enhanced recovery after surgery components and perioperative outcomes: a nationwide observational study. Br J Anaesth. 2020;124:638\u201347.","journal-title":"Br J Anaesth"},{"key":"3283_CR9","doi-asserted-by":"publisher","first-page":"84","DOI":"10.1016\/j.jss.2014.03.001","volume":"191","author":"T Yamada","year":"2014","unstructured":"Yamada T, Kan H, Matsumoto S, Koizumi M, Matsuda A, Shinji S, et al. Dysmotility by mechanical bowel preparation using polyethylene glycol. J Surg Res. 2014;191:84\u201390.","journal-title":"J Surg Res"},{"key":"3283_CR10","doi-asserted-by":"publisher","first-page":"1453","DOI":"10.1016\/S0140-6736(07)61602-X","volume":"370","author":"E von Elm","year":"2007","unstructured":"von Elm E, Altman DG, Egger M, Pocock SJ, G\u00f8tzsche PC, Vandenbroucke JP. STROBE Initiative. The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) statement: guidelines for reporting observational studies. Lancet. 2007;370:1453\u20137.","journal-title":"Lancet"},{"key":"3283_CR11","doi-asserted-by":"publisher","first-page":"611","DOI":"10.1111\/nmo.12330","volume":"26","author":"SS Yarandi","year":"2014","unstructured":"Yarandi SS, Srinivasan S. Diabetic gastrointestinal motility disorders and the role of enteric nervous system: current status and future directions. Neurogastroenterol Motil. 2014;26:611\u201324.","journal-title":"Neurogastroenterol Motil"},{"key":"3283_CR12","doi-asserted-by":"publisher","first-page":"387","DOI":"10.5056\/jnm19037","volume":"25","author":"HM Park","year":"2019","unstructured":"Park HM, Park SY, Chung JO, Cho DH, Park CH, Kim HS, et al. Association Between Gastric Emptying Time and Incidence of Cardiovascular Diseases in Subjects With Diabetes. J Neurogastroenterol Motil. 2019;25:387\u201393.","journal-title":"J Neurogastroenterol Motil"},{"key":"3283_CR13","doi-asserted-by":"publisher","first-page":"e143771","DOI":"10.1172\/JCI143771","volume":"131","author":"M Camilleri","year":"2021","unstructured":"Camilleri M. Gastrointestinal motility disorders in neurologic disease. J Clin Invest. 2021;131:e143771.","journal-title":"J Clin Invest"},{"key":"3283_CR14","doi-asserted-by":"publisher","first-page":"1145","DOI":"10.1164\/rccm.202206-1066TR","volume":"207","author":"L Wang","year":"2023","unstructured":"Wang L, Cai Y, Garssen J, Henricks PAJ, Folkerts G, Braber S. The Bidirectional Gut-Lung Axis in Chronic Obstructive Pulmonary Disease. Am J Respir Crit Care Med. 2023;207:1145\u201360.","journal-title":"Am J Respir Crit Care Med"},{"key":"3283_CR15","doi-asserted-by":"publisher","first-page":"1862","DOI":"10.3390\/microorganisms8121862","volume":"8","author":"R Ikee","year":"2020","unstructured":"Ikee R, Sasaki N, Yasuda T, Fukazawa S. Chronic Kidney Disease, Gut Dysbiosis, and Constipation: A Burdensome Triplet. Microorganisms. 2020;8:1862.","journal-title":"Microorganisms"},{"key":"3283_CR16","doi-asserted-by":"publisher","first-page":"3113","DOI":"10.1111\/codi.15969","volume":"23","author":"SHB Seo","year":"2021","unstructured":"Seo SHB, Carson DA, Bhat S, Varghese C, Wells CI, Bissett IP, et al. Prolonged postoperative ileus following right- versus left-sided colectomy: A systematic review and meta-analysis. Colorectal Dis. 2021;23:3113\u201322.","journal-title":"Colorectal Dis"},{"key":"3283_CR17","doi-asserted-by":"publisher","first-page":"504","DOI":"10.1001\/jamasurg.2013.1205","volume":"148","author":"MR Kwaan","year":"2013","unstructured":"Kwaan MR, Al-Refaie WB, Parsons HM, Chow CJ, Rothenberger DA, Habermann EB. Are right-sided colectomy outcomes different from left-sided colectomy outcomes? study of patients with colon cancer in the ACS NSQIP database. JAMA Surg. 2013;148:504\u201310.","journal-title":"JAMA Surg"},{"key":"3283_CR18","doi-asserted-by":"publisher","first-page":"1412","DOI":"10.1002\/cncr.27891","volume":"119","author":"RP Merkow","year":"2013","unstructured":"Merkow RP, Kmiecik TE, Bentrem DJ, Winchester DP, Stewart AK, Ko CY, et al. Effect of including cancer-specific variables on models examining short-term outcomes. Cancer. 2013;119:1412\u20139.","journal-title":"Cancer"},{"key":"3283_CR19","doi-asserted-by":"publisher","first-page":"375","DOI":"10.1111\/j.1463-1318.2006.00974.x","volume":"8","author":"JJ Tjandra","year":"2006","unstructured":"Tjandra JJ, Chan MK. Systematic review on the short-term outcome of laparoscopic resection for colon and rectosigmoid cancer. Colorectal disease: official J Association Coloproctology Great Br Irel. 2006;8:375\u201388.","journal-title":"Colorectal disease: official J Association Coloproctology Great Br Irel"},{"key":"3283_CR20","doi-asserted-by":"publisher","first-page":"1812","DOI":"10.1016\/S0140-6736(02)08711-1","volume":"359","author":"DN Lobo","year":"2002","unstructured":"Lobo DN, Bostock KA, Neal KR, Perkins AC, Rowlands BJ, Allison SP. Effect of salt and water balance on recovery of gastrointestinal function after elective colonic resection: a randomised controlled trial. Lancet. 2002;359:1812\u20138.","journal-title":"Lancet"},{"key":"3283_CR21","doi-asserted-by":"crossref","unstructured":"G\u00fcenaga KF, Matos D, Wille-J\u00f8rgensen P. Mechanical bowel preparation for elective colorectal surgery. Cochrane database Syst Rev. 2011;9:Cd001544.","DOI":"10.1002\/14651858.CD001544.pub4"},{"key":"3283_CR22","doi-asserted-by":"publisher","first-page":"564","DOI":"10.1053\/jpsu.2000.0350564","volume":"35","author":"M Bingol-Kologlu","year":"2000","unstructured":"Bingol-Kologlu M, Senocak ME, Talim B, Kale G, Ocal T, Buyukpamukcu N. A comparative histopathologic evaluation of the effects of three different solutions used for whole bowel irrigation: an experimental study. J Pediatr Surg. 2000;35:564\u20138.","journal-title":"J Pediatr Surg"},{"key":"3283_CR23","doi-asserted-by":"publisher","first-page":"1442","DOI":"10.1016\/j.surg.2021.05.014","volume":"170","author":"L Hartmann","year":"2021","unstructured":"Hartmann L, Arndt M, Hahn EM, Mueller MH, Kreis ME, Hering NA. Effect of bowel preparation on intestinal permeability and inflammatory response during postoperative ileus in mice. Surgery. 2021;170:1442\u20137.","journal-title":"Surgery"},{"key":"3283_CR24","doi-asserted-by":"publisher","first-page":"2224","DOI":"10.1016\/S0140-6736(02)09290-5","volume":"359","author":"AM Lacy","year":"2002","unstructured":"Lacy AM, Garcia-Valdecasas JC, Delgado S, Castells A, Taura P, Pique JM, et al. Laparoscopy-assisted colectomy versus open colectomy for treatment of non-metastatic colon cancer: a randomised trial. Lancet. 2002;359:2224\u20139.","journal-title":"Lancet"},{"key":"3283_CR25","doi-asserted-by":"publisher","first-page":"477","DOI":"10.1016\/S1470-2045(05)70221-7","volume":"6","author":"R Veldkamp","year":"2005","unstructured":"Veldkamp R, Kuhry E, Hop WC, Jeekel J, Kazemier G, Bonjer HJ, et al. Laparoscopic surgery versus open surgery for colon cancer: short-term outcomes of a randomised trial. Lancet Oncol. 2005;6:477\u201384.","journal-title":"Lancet Oncol"},{"key":"3283_CR26","doi-asserted-by":"publisher","first-page":"44","DOI":"10.1016\/S1470-2045(08)70310-3","volume":"10","author":"M Buunen","year":"2009","unstructured":"Buunen M, Veldkamp R, Hop WC, Kuhry E, Jeekel J, Haglind E, et al. Survival after laparoscopic surgery versus open surgery for colon cancer: long-term outcome of a randomised clinical trial. Lancet Oncol. 2009;10:44\u201352.","journal-title":"Lancet Oncol"},{"key":"3283_CR27","doi-asserted-by":"publisher","first-page":"415","DOI":"10.1001\/archsurg.1995.01430040077017","volume":"130","author":"B B\u00f6hm","year":"1995","unstructured":"B\u00f6hm B, Milsom JW, Fazio VW. Postoperative intestinal motility following conventional and laparoscopic intestinal surgery. Archives Surg (Chicago Ill: 1960). 1995;130:415\u20139.","journal-title":"Archives Surg (Chicago Ill: 1960)"},{"key":"3283_CR28","doi-asserted-by":"publisher","first-page":"690","DOI":"10.1007\/BF01072353","volume":"23","author":"L Bueno","year":"1978","unstructured":"Bueno L, Ferre JP, Ruckebusch Y. Effects of anesthesia and surgical procedures on intestinal myoelectric activity in rats. Am J Dig Dis. 1978;23:690\u20135.","journal-title":"Am J Dig Dis"},{"key":"3283_CR29","doi-asserted-by":"publisher","first-page":"1153","DOI":"10.1097\/SLA.0000000000001029","volume":"261","author":"Group tEC","year":"2015","unstructured":"Group tEC. The Impact of Enhanced Recovery Protocol Compliance on Elective Colorectal Cancer Resection: Results From an International Registry. Ann Surg. 2015;261:1153\u20139.","journal-title":"Ann Surg"},{"key":"3283_CR30","first-page":"469","volume":"14","author":"AH Chowdhury","year":"2011","unstructured":"Chowdhury AH, Lobo DN. Fluids and gastrointestinal function. Curr Opin Clin Nutr Metab Care. 2011;14:469\u201376.","journal-title":"Curr Opin Clin Nutr Metab Care"},{"key":"3283_CR31","doi-asserted-by":"publisher","first-page":"1433","DOI":"10.1016\/j.ejso.2017.04.003","volume":"43","author":"D Asklid","year":"2017","unstructured":"Asklid D, Segelman J, Gedda C, Hjern F, Pekkari K, Gustafsson UO. The impact of perioperative fluid therapy on short-term outcomes and 5-year survival among patients undergoing colorectal cancer surgery \u2013 A prospective cohort study within an ERAS protocol. Eur J Surg Oncol (EJSO). 2017;43:1433\u20139.","journal-title":"Eur J Surg Oncol (EJSO)"},{"key":"3283_CR32","doi-asserted-by":"crossref","unstructured":"Varadhan KK, Lobo DN. A meta-analysis of randomised controlled trials of intravenous fluid therapy in major elective open abdominal surgery: getting the balance right. The Proceedings of the Nutrition Society. 2010;69:488\u2013498.","DOI":"10.1017\/S0029665110001734"},{"key":"3283_CR33","doi-asserted-by":"publisher","first-page":"186","DOI":"10.1002\/bjs.7702","volume":"99","author":"M Abraham-Nordling","year":"2012","unstructured":"Abraham-Nordling M, Hjern F, Pollack J, Prytz M, Borg T, Kressner U. Randomized clinical trial of fluid restriction in colorectal surgery. Br J Surg. 2012;99:186\u201391.","journal-title":"Br J Surg"},{"key":"3283_CR34","doi-asserted-by":"publisher","first-page":"689","DOI":"10.1002\/bjs.5816","volume":"94","author":"B Jung","year":"2007","unstructured":"Jung B, Pahlman L, Nystrom PO, Nilsson E. Multicentre randomized clinical trial of mechanical bowel preparation in elective colonic resection. Br J Surg. 2007;94:689\u201395.","journal-title":"Br J Surg"},{"key":"3283_CR35","doi-asserted-by":"publisher","first-page":"2112","DOI":"10.1016\/S0140-6736(07)61905-9","volume":"370","author":"CM Contant","year":"2007","unstructured":"Contant CM, Hop WC, van\u2019t Sant HP, Oostvogel HJ, Smeets HJ, Stassen LP, et al. Mechanical bowel preparation for elective colorectal surgery: a multicentre randomised trial. Lancet. 2007;370:2112\u20137.","journal-title":"Lancet"},{"key":"3283_CR36","doi-asserted-by":"publisher","first-page":"1051","DOI":"10.1097\/SLA.0000000000001576","volume":"264","author":"AA Althumairi","year":"2016","unstructured":"Althumairi AA, Canner JK, Pawlik TM, Schneider E, Nagarajan N, Safar B, et al. Benefits of Bowel Preparation Beyond Surgical Site Infection: A Retrospective Study. Ann Surg. 2016;264:1051\u20137.","journal-title":"Ann Surg"},{"key":"3283_CR37","doi-asserted-by":"publisher","first-page":"e183226","DOI":"10.1001\/jamanetworkopen.2018.3226","volume":"1","author":"JWT Toh","year":"2018","unstructured":"Toh JWT, Phan K, Hitos K, Pathma-Nathan N, El-Khoury T, Richardson AJ, et al. Association of Mechanical Bowel Preparation and Oral Antibiotics Before Elective Colorectal Surgery With Surgical Site Infection: A Network Meta-analysis. JAMA Netw Open. 2018;1:e183226.","journal-title":"JAMA Netw Open"},{"key":"3283_CR38","doi-asserted-by":"crossref","unstructured":"Smith J, Kelly KA, Weinshilboum RM. Pathophysiology of postoperative ileus. Archives of surgery (Chicago, Ill: 1960) 1977;112:203\u2013209.","DOI":"10.1001\/archsurg.1977.01370020097011"}],"container-title":["Surgery Today"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00595-026-03283-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00595-026-03283-3","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00595-026-03283-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,17]],"date-time":"2026-07-17T11:40:59Z","timestamp":1784288459000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00595-026-03283-3"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3,26]]},"references-count":38,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2026,8]]}},"alternative-id":["3283"],"URL":"https:\/\/doi.org\/10.1007\/s00595-026-03283-3","relation":{},"ISSN":["0941-1291","1436-2813"],"issn-type":[{"value":"0941-1291","type":"print"},{"value":"1436-2813","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,3,26]]},"assertion":[{"value":"14 June 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"28 February 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"26 March 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The authors declare no potential conflicts of interest.","order":1,"name":"Ethics","label":"Conflict of interest","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"This study was approved by the Ethics Committee for the local Institutional Review Board of Nippon Medical School (Approval No. B-2020-144).","order":2,"name":"Ethics","label":"Ethical approval","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"N\/A","order":3,"name":"Ethics","label":"Informed Consent","group":{"name":"EthicsHeading","label":"Declarations"}}]}}