{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,6]],"date-time":"2026-03-06T20:43:03Z","timestamp":1772829783842,"version":"3.50.1"},"reference-count":34,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2019,1,9]],"date-time":"2019-01-09T00:00:00Z","timestamp":1546992000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Microchim Acta"],"published-print":{"date-parts":[[2019,2]]},"DOI":"10.1007\/s00604-018-3199-2","type":"journal-article","created":{"date-parts":[[2019,1,9]],"date-time":"2019-01-09T05:55:46Z","timestamp":1547013346000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["Multifunctional DNA nanocage with CdTe quantum dots for fluorescence detection of human 8-oxoG DNA glycosylase 1 and doxorubicin delivery to cancer cells"],"prefix":"10.1007","volume":"186","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6416-6523","authenticated-orcid":false,"given":"Guifen","family":"Jie","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaoshan","family":"Gao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Junjun","family":"Ge","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chunli","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2019,1,9]]},"reference":[{"key":"3199_CR1","doi-asserted-by":"publisher","first-page":"6130","DOI":"10.1021\/cr200359p","volume":"114","author":"J Yao","year":"2014","unstructured":"Yao J, Yang M, Duan Y (2014) Chemistry, biology, and medicine of fluorescent nanomaterials and related systems: new insights into biosensing, bioimaging, genomics, diagnostics, and therapy. Chem Rev 114:6130\u20136178","journal-title":"Chem Rev"},{"key":"3199_CR2","doi-asserted-by":"publisher","first-page":"2013","DOI":"10.1126\/science.281.5385.2013","volume":"281","author":"MJ Bruchez","year":"1998","unstructured":"Bruchez MJ, Moronne M, Gin P, Weiss S, Alivisatos AP (1998) Semiconductor nanocrystals as fluorescent biological labels. Science 281:2013\u20132016","journal-title":"Science"},{"key":"3199_CR3","doi-asserted-by":"publisher","first-page":"3048","DOI":"10.1021\/ja0685452","volume":"129","author":"H Peng","year":"2007","unstructured":"Peng H, Zhang L, Kjallman THM, Soeller C, Travas-Sejdik J (2007) DNA hybridization detection with blue luminescent quantum dots and dye-labeled single-stranded DNA. J Am Chem Soc 129:3048\u20133049","journal-title":"J Am Chem Soc"},{"key":"3199_CR4","doi-asserted-by":"publisher","first-page":"1026","DOI":"10.1016\/j.snb.2017.06.107","volume":"252","author":"GF Jie","year":"2017","unstructured":"Jie GF, ZhaoY WXC, Ding CF (2017) Multiplexed fluorescence detection of microRNAs based on novel distinguishable quantum dot signal probes by cycle amplification strategy. Sensors Actuators B 252:1026\u20131034","journal-title":"Sensors Actuators B"},{"key":"3199_CR5","first-page":"125","volume":"273\/274","author":"N Hildebrandt","year":"2014","unstructured":"Hildebrandt N, Wegner KD, Algar WR (2014) Luminescent terbium complexes: superior F\u00f6rster resonance energy transfer donors for flexible and sensitive multiplexed biosensing. Chem Rev 273\/274:125\u2013138","journal-title":"Chem Rev"},{"key":"3199_CR6","first-page":"65","volume":"263\/264","author":"WR Algar","year":"2014","unstructured":"Algar WR, Kim H, Medintz IL, Hildebrandt N (2014) Emerging non-traditional F\u00f6rster resonance energy transfer configurations with semiconductor quantum dots: investigations and applications. Chem Rev 263\/264:65\u201385","journal-title":"Chem Rev"},{"key":"3199_CR7","doi-asserted-by":"publisher","first-page":"1887","DOI":"10.1016\/j.bios.2005.10.027","volume":"21","author":"J Wang","year":"2006","unstructured":"Wang J (2006) Electrochemical biosensors: towards point-of-care cancer diagnostics. Biosens Bioelectron 21:1887\u20131892","journal-title":"Biosens Bioelectron"},{"key":"3199_CR8","doi-asserted-by":"publisher","first-page":"4527","DOI":"10.1039\/C5SC04920B","volume":"7","author":"ZF Chang","year":"2016","unstructured":"Chang ZF, Jing LM, Chen B, Zhang MS, Cai XL, Liu JJ, Ye YC, Lou XD, Zhao ZJ, Liu B, Wang JL, Tang BZ (2016) Rational design of asymmetric red fluorescent probes for live cell imaging with high AIE effects and large two-photon absorption cross sections using tunable. Chem Sci 7:4527\u2013\u22124536","journal-title":"Chem Sci"},{"key":"3199_CR9","doi-asserted-by":"publisher","first-page":"1058","DOI":"10.1021\/ac302923k","volume":"85","author":"Y Zhu","year":"2013","unstructured":"Zhu Y, Chandra P, Shim Y (2013) Ultrasensitive and selective electrochemical diagnosis of breast cancer based on a hydrazine\u2013Au nanoparticle\u2013aptamer bioconjugate. Anal Chem 85:1058\u20131064","journal-title":"Anal Chem"},{"key":"3199_CR10","doi-asserted-by":"publisher","first-page":"715","DOI":"10.1039\/C3SC52838C","volume":"5","author":"JS Basuki","year":"2014","unstructured":"Basuki JS, Esser L, Duong HTT, Zhang Q, Wilson P, Whittaker MR, Haddleton DM, Boyer C, Davis TP (2014) Magnetic nanoparticles with diblock glycopolymer shells give lectin concentration-dependent MRI signals and selective cell uptake. Chem Sci 5:715\u2013726","journal-title":"Chem Sci"},{"key":"3199_CR11","doi-asserted-by":"publisher","first-page":"5116","DOI":"10.1021\/ac500951v","volume":"86","author":"J Wang","year":"2014","unstructured":"Wang J, Christison T, Misuno K, Lopez L, Huhmer A, Huang Y, Hu S (2014) Metabolomic profiling of anionic metabolites in head and neck cancer cells by capillary ion chromatography with Orbitrap mass spectrometry. Anal Chem 86:5116\u20135124","journal-title":"Anal Chem"},{"key":"3199_CR12","doi-asserted-by":"publisher","first-page":"12116","DOI":"10.1039\/c1cc15695k","volume":"47","author":"X Chen","year":"2011","unstructured":"Chen X, Lin YH, Li J, Lin L-S, Chen G-N, Yang H-H (2011) A simple and ultrasensitive electrochemical DNA biosensor based on DNA concatamers. Chem Commun 47:12116\u201312118","journal-title":"Chem Commun"},{"key":"3199_CR13","doi-asserted-by":"publisher","first-page":"401","DOI":"10.1002\/anie.201005375","volume":"50","author":"J Huang","year":"2011","unstructured":"Huang J, Wu YR, Chen Y, Zhu Z, Yang XH, Yang CJ, Wang KM, Tan WH (2011) Pyrene-excimer probes based on the hybridization chain reaction for the detection of nucleic acids in complex biological fluids. Angew Chem Int Ed 50:401\u2013404","journal-title":"Angew Chem Int Ed"},{"key":"3199_CR14","doi-asserted-by":"publisher","first-page":"5939","DOI":"10.1021\/ac3004727","volume":"84","author":"JH Huang","year":"2012","unstructured":"Huang JH, Su XF, Li ZG (2012) Enzyme-free and amplified fluorescence DNA detection using bimolecular beacons. Anal Chem 84:5939\u20135943","journal-title":"Anal Chem"},{"key":"3199_CR15","doi-asserted-by":"publisher","first-page":"2811","DOI":"10.1021\/ac203261x","volume":"84","author":"GF Jie","year":"2012","unstructured":"Jie GF, Yuan JX (2012) Novel magnetic Fe3O4@CdSe composite quantum dot-based Electrochemiluminescence detection of thrombin by a multiple DNA cycle amplification strategy. Anal Chem 84:2811\u20132817","journal-title":"Anal Chem"},{"key":"3199_CR16","doi-asserted-by":"publisher","first-page":"2097","DOI":"10.1002\/smll.201202739","volume":"9","author":"Y He","year":"2013","unstructured":"He Y, Xing XJ, Tang HW, Pang DW (2013) Graphene oxide-based fluorescent biosensor for protein detection via terminal protection of small-molecule-linked DNA. Small 9:2097\u20132101","journal-title":"Small"},{"key":"3199_CR17","doi-asserted-by":"publisher","first-page":"2895","DOI":"10.1039\/c0cc04566g","volume":"47","author":"C Shi","year":"2011","unstructured":"Shi C, Zhao CH, Guo QJ, Ma CP (2011) Entropy-driven molecular switch and signal amplification for homogeneous SNPs detection. Chem Commun 47:2895\u20132897","journal-title":"Chem Commun"},{"key":"3199_CR18","doi-asserted-by":"publisher","first-page":"857","DOI":"10.1016\/j.snb.2016.09.055","volume":"240","author":"GF Jie","year":"2017","unstructured":"Jie GF, Lu ZK, Zhao Y, Wang XC (2017) Quantum dots bilayers\/au@ag-based electrochemiluminescence resonance energy transfer for detection of thrombin by autocatalytic multiple amplification strategy. Sensors Actuators B 240:857\u2013862","journal-title":"Sensors Actuators B"},{"key":"3199_CR19","doi-asserted-by":"publisher","first-page":"4717","DOI":"10.1016\/j.biomaterials.2007.07.014","volume":"28","author":"T Jamieson","year":"2007","unstructured":"Jamieson T, Bakhshi R, Petrova D (2007) Biological applications of quantum dots. Biomaterials 28:4717\u20134732","journal-title":"Biomaterials"},{"key":"3199_CR20","doi-asserted-by":"publisher","first-page":"9696","DOI":"10.1021\/nn203161y","volume":"5","author":"VJ Sch\u00fcller","year":"2011","unstructured":"Sch\u00fcller VJ, Heidegger S, Sandholzer N (2011) Cellular Immunostimulation by CpG-sequence-coated DNA origami structures. ACS Nano 5:9696\u20139702","journal-title":"ACS Nano"},{"key":"3199_CR21","doi-asserted-by":"publisher","first-page":"8439","DOI":"10.1021\/bi000474a","volume":"39","author":"J Ren","year":"2000","unstructured":"Ren J, Jenkins TC, Chaires JB (2000) Energetics of DNA intercalation reactions. Biochemistry 39:8439\u20138447","journal-title":"Biochemistry"},{"key":"3199_CR22","first-page":"225","volume":"33","author":"DR Phillips","year":"1988","unstructured":"Phillips DR, Greif PC, Boston RC (1988) Daunomycin-DNA dissociation kinetics. Mol Pharmacol 33:225\u2013230","journal-title":"Mol Pharmacol"},{"key":"3199_CR23","doi-asserted-by":"publisher","first-page":"1813","DOI":"10.1093\/nar\/gki325","volume":"33","author":"L Luna","year":"2005","unstructured":"Luna L, Rolseth V, Hildrestrand GA (2005) Dynamic relocalization of hOGG1 during the cell cycle is disrupted in cells harbouring the hOGG1-Cys326 polymorphic variant. Nucleic Acids Res 33:1813\u20131824","journal-title":"Nucleic Acids Res"},{"key":"3199_CR24","doi-asserted-by":"publisher","first-page":"1620","DOI":"10.1093\/nar\/gkl060","volume":"34","author":"JW Hill","year":"2006","unstructured":"Hill JW, Evans MK (2006) Dimerization and opposite base-dependent catalytic impairment of polymorphic S326C OGG1 glycosylase. Nucleic Acids Res 34:1620\u20131632","journal-title":"Nucleic Acids Res"},{"key":"3199_CR25","doi-asserted-by":"publisher","first-page":"1123","DOI":"10.1111\/j.1349-7006.2011.01928.x","volume":"102","author":"Q Li","year":"2011","unstructured":"Li Q, Huang L, Rong L (2011) hOGG1 Ser326Cys polymorphism and risk of childhood acute lymphoblastic leukemia in a Chinese population. Cancer Sci 102:1123\u20131127","journal-title":"Cancer Sci"},{"key":"3199_CR26","doi-asserted-by":"publisher","first-page":"54","DOI":"10.1002\/em.21742","volume":"54","author":"YH Su","year":"2013","unstructured":"Su YH, Lee YL, Chen SF, Lee YP, Hsieh YH, Tsai JH, Hsu JL, Tian WT, Huang WY (2013) Essential role of \u03b2-human 8-oxoguanine DNA glycosylase 1 in mitochondrial oxidative DNA repair. Environ Mol Mutagen 54:54\u201364","journal-title":"Environ Mol Mutagen"},{"key":"3199_CR27","first-page":"4899","volume":"63","author":"D Gackowski","year":"2003","unstructured":"Gackowski D, Speina E, Zielinska M, Kowalewski J, Rozalski R, Siomek A, Paciorek T, Tudek B, Olinski R (2003) Products of oxidative DNA damage and repair as possible biomarkers of susceptibility to lung cancer. Cancer Res 63:4899\u20134902","journal-title":"Cancer Res"},{"key":"3199_CR28","doi-asserted-by":"publisher","first-page":"127","DOI":"10.1002\/mc.20067","volume":"42","author":"JM Weiss","year":"2005","unstructured":"Weiss JM, Goode EL, Ladiges WC, Ulrich CM (2005) Polymorphic variation in hOGG1 and risk of cancer: A review of the functional and epidemiologic literature. Mol Carcinog 42:127\u2013141","journal-title":"Mol Carcinog"},{"key":"3199_CR29","doi-asserted-by":"publisher","first-page":"7","DOI":"10.1016\/j.bios.2014.12.048","volume":"68","author":"F Yuan","year":"2015","unstructured":"Yuan F, Zhao HM, Liu M, Quan X (2015) Visible assay for glycosylase based on intrinsic catalytic ability of graphene\/gold nanoparticles hybrids. Biosens Bioelectron 68:7\u201313","journal-title":"Biosens Bioelectron"},{"key":"3199_CR30","doi-asserted-by":"publisher","first-page":"9626","DOI":"10.1021\/ac502125z","volume":"86","author":"XZ Wang","year":"2014","unstructured":"Wang XZ, Hou T, Lu TT, Li F (2014) Autonomous exonuclease III-assisted isothermal cycling signal amplification: a facile and highly sensitive fluorescence DNA glycosylase activity assay. Anal Chem 86:9626\u20139631","journal-title":"Anal Chem"},{"key":"3199_CR31","doi-asserted-by":"publisher","first-page":"770","DOI":"10.1002\/smll.201503051","volume":"2","author":"MS Chan","year":"2016","unstructured":"Chan MS, Tam DY, Dai Q (2016) Mitochondrial delivery of therapeutic agents by amphiphilic DNA Nanocarriers. Small 2:770\u2013781","journal-title":"Small"},{"key":"3199_CR32","doi-asserted-by":"publisher","first-page":"5990","DOI":"10.1002\/anie.201500755","volume":"54","author":"Y Li","year":"2015","unstructured":"Li Y, Tian C, Liu Z (2015) Structural transformation: assembly of an otherwise inaccessible DNA Nanocage. Angew Chem Int Ed 54:5990\u20135993","journal-title":"Angew Chem Int Ed"},{"key":"3199_CR33","doi-asserted-by":"publisher","first-page":"1326","DOI":"10.1021\/acs.biochem.5b01181","volume":"55","author":"Z Xia","year":"2016","unstructured":"Xia Z, Wang P, Liu X (2016) Tumor-penetrating peptide-modified DNA tetrahedron for targeting drug delivery. Biochemistry 55:1326\u20131331","journal-title":"Biochemistry"},{"key":"3199_CR34","doi-asserted-by":"publisher","first-page":"175","DOI":"10.1016\/j.nano.2014.08.013","volume":"11","author":"X Li","year":"2015","unstructured":"Li X, Yu Y, Ji Q (2015) Targeted delivery of anticancer drugs by aptamer AS1411 mediated Pluronic F127\/cyclodextrin-linked polymer composite micelles. Nanomed-Nanotechnol 11:175\u2013184","journal-title":"Nanomed-Nanotechnol"}],"container-title":["Microchimica Acta"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00604-018-3199-2\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00604-018-3199-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00604-018-3199-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,1,8]],"date-time":"2020-01-08T19:14:57Z","timestamp":1578510897000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00604-018-3199-2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,1,9]]},"references-count":34,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2019,2]]}},"alternative-id":["3199"],"URL":"https:\/\/doi.org\/10.1007\/s00604-018-3199-2","relation":{},"ISSN":["0026-3672","1436-5073"],"issn-type":[{"value":"0026-3672","type":"print"},{"value":"1436-5073","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,1,9]]},"assertion":[{"value":"9 October 2018","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"20 December 2018","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"9 January 2019","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The author(s) declare that they have no competing interests.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}}],"article-number":"85"}}