{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T19:53:20Z","timestamp":1791575600190,"version":"4.3.4"},"reference-count":34,"publisher":"Springer Science and Business Media LLC","issue":"12","license":[{"start":{"date-parts":[[2019,11,20]],"date-time":"2019-11-20T00:00:00Z","timestamp":1574208000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2019,11,20]],"date-time":"2019-11-20T00:00:00Z","timestamp":1574208000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"funder":[{"name":"ajor Infectious Diseases such as AIDS and Viral Hepatitis Prevention and Control Technology Major Projects","award":["2018ZX10712-001"],"award-info":[{"award-number":["2018ZX10712-001"]}]},{"name":"the Major Projects","award":["No. AWS16J020"],"award-info":[{"award-number":["No. AWS16J020"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Microchim Acta"],"published-print":{"date-parts":[[2019,12]]},"DOI":"10.1007\/s00604-019-3964-x","type":"journal-article","created":{"date-parts":[[2019,11,20]],"date-time":"2019-11-20T00:34:49Z","timestamp":1574210089000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":33,"title":["Ovalbumin antibody-based fluorometric immunochromatographic lateral flow assay using CdSe\/ZnS quantum dot beads as label for determination of\u00a0T-2 toxin"],"prefix":"10.1007","volume":"186","author":[{"given":"Zhiwei","family":"Qie","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenliang","family":"Yan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zichen","family":"Gao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wu","family":"Meng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rui","family":"Xiao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shengqi","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2019,11,20]]},"reference":[{"key":"3964_CR1","doi-asserted-by":"publisher","first-page":"2","DOI":"10.3390\/bios9010002","volume":"9","author":"L Anfossi","year":"2019","unstructured":"Anfossi L, Di Nardo F, Cavalera S, Giovannoli C, Baggiani C (2019) Multiplex lateral flow immunoassay: an overview of strategies towards high-throughput point-of-need testing. Biosensors 9:2\u201314. https:\/\/doi.org\/10.3390\/bios9010002","journal-title":"Biosensors"},{"key":"3964_CR2","doi-asserted-by":"publisher","first-page":"1567","DOI":"10.1016\/j.cclet.2017.12.008","volume":"29","author":"S Zhao","year":"2018","unstructured":"Zhao S, Wang S, Zhang S, Liu J, Dong Y (2018) State of the art: lateral flow assay (LFA) biosensor for on-site rapid detection. Chin Chem Lett 29:1567\u20131577. https:\/\/doi.org\/10.1016\/j.cclet.2017.12.008","journal-title":"Chin Chem Lett"},{"key":"3964_CR3","doi-asserted-by":"publisher","first-page":"2501","DOI":"10.3168\/jds.2016-12065","volume":"100","author":"C Wu","year":"2017","unstructured":"Wu C, Hu L, Xia J, Xu G, Luo K, Liu D, Duan H, Cheng S, Xiong Y, Lai W (2017) Comparison of immunoassays based on fluorescent microsphere and quantum-dot submicrobead for quantitative detection of aflatoxin M1 in milk. J Dairy Sci 100:2501\u20132511. https:\/\/doi.org\/10.3168\/jds.2016-12065","journal-title":"J Dairy Sci"},{"key":"3964_CR4","doi-asserted-by":"publisher","first-page":"4313","DOI":"10.1007\/s00604-017-2474-y","volume":"184","author":"W Sheng","year":"2017","unstructured":"Sheng W, Li S, Liu Y, Wang J, Zhang Y, Wang S (2017) Visual and rapid lateral flow immunoassay for enrofloxacin using dyed polymer microspheres and quantum dots. Mikrochim Acta 184:4313\u20134321. https:\/\/doi.org\/10.1007\/s00604-017-2474-y","journal-title":"Mikrochim Acta"},{"key":"3964_CR5","doi-asserted-by":"publisher","first-page":"5176","DOI":"10.3168\/jds.2017-12554","volume":"100","author":"K Luo","year":"2017","unstructured":"Luo K, Hu L, Guo Q, Wu C, Wu S, Liu D, Xiong Y, Lai W (2017) Comparison of 4 label-based immunoassays for the detection of Escherichia coli O157:H7 in milk. J Dairy Sci 100:5176\u20135187. https:\/\/doi.org\/10.3168\/jds.2017-12554","journal-title":"J Dairy Sci"},{"key":"3964_CR6","doi-asserted-by":"publisher","first-page":"52","DOI":"10.1016\/j.aca.2017.10.027","volume":"998","author":"KY Xing","year":"2018","unstructured":"Xing KY, Peng J, Liu DF, Hu LM, Wang C, Li GQ, Zhang GG, Huang Z, Cheng S, Zhu FF, Liu NM, Lai WH (2018) Novel immunoassay based on Eu (III)-doped polystyrene nanoparticle-linker-monoclonal antibody for sensitive detection of Escherichia coli O157:H7. Anal Chim Acta 998:52\u201359. https:\/\/doi.org\/10.1016\/j.aca.2017.10.027","journal-title":"Anal Chim Acta"},{"key":"3964_CR7","doi-asserted-by":"publisher","first-page":"131","DOI":"10.1016\/j.foodchem.2018.04.016","volume":"261","author":"L Yan","year":"2018","unstructured":"Yan L, Dou L, Bu T, Huang Q, Wang R, Yang Q, Huang L, Wang J, Zhang D (2018) Highly sensitive furazolidone monitoring in milk by a signal amplified lateral flow assay based on magnetite nanoparticles labeled dual-probe. Food Chem 261:131\u2013138. https:\/\/doi.org\/10.1016\/j.foodchem.2018.04.016","journal-title":"Food Chem"},{"key":"3964_CR8","doi-asserted-by":"publisher","first-page":"5770","DOI":"10.3168\/jds.2018-14429","volume":"101","author":"J Han","year":"2018","unstructured":"Han J, Zhang L, Hu L, Xing K, Lu X, Huang Y, Zhang J, Lai W, Chen T (2018) Nanozyme-based lateral flow assay for the sensitive detection of Escherichia coli O157:H7 in milk. J Dairy Sci 101:5770\u20135779. https:\/\/doi.org\/10.3168\/jds.2018-14429","journal-title":"J Dairy Sci"},{"key":"3964_CR9","doi-asserted-by":"publisher","first-page":"536","DOI":"10.1016\/j.foodcont.2017.08.036","volume":"84","author":"T Bu","year":"2018","unstructured":"Bu T, Huang Q, Yan L, Huang L, Zhang M, Yang Q, Yang B, Wang J, Zhang D (2018) Ultra technically-simple and sensitive detection for Salmonella Enteritidis by immunoassay based on gold growth. Food Control 84:536\u2013543. https:\/\/doi.org\/10.1016\/j.foodcont.2017.08.036","journal-title":"Food Control"},{"key":"3964_CR10","doi-asserted-by":"publisher","first-page":"304","DOI":"10.1016\/j.foodchem.2018.02.002","volume":"256","author":"J Zhou","year":"2018","unstructured":"Zhou J, Nie W, Chen Y, Yang C, Gong L, Zhang C, Chen Q, He L, Feng X (2018) Quadruplex gold immunoassay for four families of antibiotic residues in milk. Food Chem 256:304\u2013310. https:\/\/doi.org\/10.1016\/j.foodchem.2018.02.002","journal-title":"Food Chem"},{"key":"3964_CR11","doi-asserted-by":"publisher","first-page":"40671","DOI":"10.1021\/acsami.7b12734","volume":"9","author":"N Cheng","year":"2017","unstructured":"Cheng N, Song Y, Zeinhom MMA, Chang YC, Sheng L, Li H, Du D, Li L, Zhu MJ, Luo Y, Xu W, Lin Y (2017) Nanozyme-mediated dual immunoassay integrated with smartphone for use in simultaneous detection of pathogens. ACS Appl Mater Interfaces 9:40671\u201340680. https:\/\/doi.org\/10.1021\/acsami.7b12734","journal-title":"ACS Appl Mater Interfaces"},{"key":"3964_CR12","doi-asserted-by":"publisher","first-page":"1989","DOI":"10.1007\/s00604-016-1812-9","volume":"183","author":"YH Zhong","year":"2016","unstructured":"Zhong YH, Chen YJ, Yao L, Zhao DP, Zheng L, Liu GD, Ye Y, Chen WW (2016) Gold nanoparticles based lateral flow immunoassay with largely amplified sensitivity for rapid melamine screening. Mikrochim Acta 183:1989\u20131994. https:\/\/doi.org\/10.1007\/s00604-016-1812-9","journal-title":"Mikrochim Acta"},{"issue":"7","key":"3964_CR13","doi-asserted-by":"publisher","first-page":"436","DOI":"10.1007\/s00604-019-3508-4","volume":"186","author":"WW Qiu","year":"2019","unstructured":"Qiu WW, Baryeh K, Takalkar S, Chen W, Liu GD (2019) Carbon nanotube-based lateral flow immunoassay for ultrasensitive detection of proteins: application to the determination of IgG. Microchim Acta 186(7):436\u2013444. https:\/\/doi.org\/10.1007\/s00604-019-3508-4","journal-title":"Microchim Acta"},{"issue":"1","key":"3964_CR14","doi-asserted-by":"publisher","first-page":"2","DOI":"10.1007\/s00604-018-3107-9","volume":"186","author":"XW Lu","year":"2019","unstructured":"Lu XW, Mei T, Guo Q, Zhou WJ, Li XM, Chen JT, Zhou XK, Sun N, Fang ZY (2019) Improved performance of lateral flow immunoassays for alpha-fetoprotein and vanillin by using silica shell-stabilized gold nanoparticles. Microchim Acta 186(1):2\u20139. https:\/\/doi.org\/10.1007\/s00604-018-3107-9","journal-title":"Microchim Acta"},{"issue":"2","key":"3964_CR15","doi-asserted-by":"publisher","first-page":"94","DOI":"10.1007\/s00604-017-2642-0","volume":"185","author":"L Anfossi","year":"2018","unstructured":"Anfossi L, Di Nardo F, Cavalera S, Giovannoli C, Spano G, Speranskaya ES, Goryacheva IY, Baggiani C (2018) A lateral flow immunoassay for straightforward determination of fumonisin mycotoxins based on the quenching of the fluorescence of CdSe\/ZnS quantum dots by gold and silver nanoparticles. Microchim Acta 185(2):94\u2013104. https:\/\/doi.org\/10.1007\/s00604-017-2642-0","journal-title":"Microchim Acta"},{"issue":"9","key":"3964_CR16","doi-asserted-by":"publisher","first-page":"404","DOI":"10.1007\/s00604-018-2945-9","volume":"185","author":"W Sheng","year":"2018","unstructured":"Sheng W, Chang Q, Shi YJ, Duan WX, Zhang Y, Wang S (2018) Visual and fluorometric lateral flow immunoassay combined with a dual-functional test mode for rapid determination of tetracycline antibiotics. Microchim Acta 185(9):404\u2013414. https:\/\/doi.org\/10.1007\/s00604-018-2945-9","journal-title":"Microchim Acta"},{"key":"3964_CR17","doi-asserted-by":"publisher","first-page":"525","DOI":"10.1016\/j.foodchem.2017.04.147","volume":"233","author":"L Chen","year":"2017","unstructured":"Chen L, Tian Y, Sun B, Wang J, Tong Q, Jin Z (2017) Rapid, accurate, and simultaneous measurement of water and oil contents in the fried starchy system using low-field NMR. Food Chem 233:525\u2013529. https:\/\/doi.org\/10.1016\/j.foodchem.2017.04.147","journal-title":"Food Chem"},{"key":"3964_CR18","doi-asserted-by":"publisher","first-page":"613","DOI":"10.1016\/j.meatsci.2011.10.002","volume":"90","author":"Z Zou","year":"2012","unstructured":"Zou Z, He Z, Li H, Han P, Tang J, Xi C, Li Y, Zhang L, Li X (2012) Development and application of a method for the analysis of two trichothecenes: Deoxynivalenol and T-2 toxin in meat in China by HPLC-MS\/MS. Meat Sci 90:613\u2013617. https:\/\/doi.org\/10.1016\/j.meatsci.2011.10.002","journal-title":"Meat Sci"},{"key":"3964_CR19","doi-asserted-by":"publisher","first-page":"75","DOI":"10.1016\/j.jchromb.2014.03.010","volume":"958","author":"Y Sun","year":"2014","unstructured":"Sun Y, Zhang G, Zhao H, Zheng J, Hu F, Fang B (2014) Liquid chromatography\u2013tandem mass spectrometry method for toxicokinetics, tissue distribution, and excretion studies of T-2 toxin and its major metabolites in pigs. J Chromatogr B 958:75\u201382. https:\/\/doi.org\/10.1016\/j.jchromb.2014.03.010","journal-title":"J Chromatogr B"},{"key":"3964_CR20","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.chroma.2006.08.078","volume":"1133","author":"S Ler","year":"2006","unstructured":"Ler S, Lee F, Gopalakrishnakone P (2006) Trends in detection of warfare agents: detection methods for ricin, staphylococcal entertoxin B and T-2 toxin. J Chromatogr A 1133:1\u201312. https:\/\/doi.org\/10.1016\/j.chroma.2006.08.078","journal-title":"J Chromatogr A"},{"key":"3964_CR21","doi-asserted-by":"publisher","first-page":"441","DOI":"10.1016\/j.ecoenv.2017.04.037","volume":"142","author":"Q Deng","year":"2017","unstructured":"Deng Q, Qiu M, Wang Y, Lv P, Wu C, Sun L, Ye R, Xu D, Liu Y, Gooneratne R (2017) A sensitive and validated immunomagnetic- bead based enzyme-linked immunosorbent assay for analyzing total T-2 (free and modified) toxins in shrimp tissues. Ecotoxicol Environ Saf 142:441\u2013447. https:\/\/doi.org\/10.1016\/j.ecoenv.2017.04.037","journal-title":"Ecotoxicol Environ Saf"},{"key":"3964_CR22","doi-asserted-by":"publisher","first-page":"328","DOI":"10.1016\/j.snb.2018.09.021","volume":"277","author":"IM Khan","year":"2018","unstructured":"Khan IM, Zhao S, Niazi S, Mohsin A, Shoaib M, Duan N, Wu S, Wang Z (2018) Silver nanoclusters based FRET aptasensor for sensitive and selective fluorescent detection of T-2 toxin. Sensors Actuators B Chem 277:328\u2013335. https:\/\/doi.org\/10.1016\/j.snb.2018.09.021","journal-title":"Sensors Actuators B Chem"},{"key":"3964_CR23","doi-asserted-by":"publisher","first-page":"3310","DOI":"10.1007\/s12161-016-0527-1","volume":"9","author":"ACR Porricelli","year":"2016","unstructured":"Porricelli ACR, Lippolis V, Valenzano S, Cortese M, Suman M, Zanardi S, Pascale M (2016) Optimization and validation of a fluorescence polarization immunoassay for rapid detection of T-2 and HT-2 toxins in cereals and cereal-based products. Food Anal Methods 9:3310\u20133318. https:\/\/doi.org\/10.1007\/s12161-016-0527-1","journal-title":"Food Anal Methods"},{"key":"3964_CR24","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.foodcont.2017.01.016","volume":"77","author":"C Wang","year":"2017","unstructured":"Wang C, Li X, Peng T, Wang Z, Wen K, Jiang H (2017) Latex bead and colloidal gold applied in a multiplex immunoassay for high-throughput detection of three classes of antibiotic residues in milk. Food Control 77:1\u20137. https:\/\/doi.org\/10.1016\/j.foodcont.2017.01.016","journal-title":"Food Control"},{"key":"3964_CR25","doi-asserted-by":"publisher","first-page":"5245","DOI":"10.1039\/C5NR09171C","volume":"8","author":"D Kong","year":"2016","unstructured":"Kong D, Liu L, Song S, Suryoprabowo S, Li A, Kuang H, Wang L, Xu C (2016) A gold nanoparticle-based semi-quantitative and quantitative ultrasensitive paper sensor for the detection of twenty mycotoxins. Nanoscale 8:5245\u20135253. https:\/\/doi.org\/10.1039\/C5NR09171C","journal-title":"Nanoscale"},{"key":"3964_CR26","doi-asserted-by":"publisher","first-page":"609","DOI":"10.1021\/acs.bioconjchem.5b00069","volume":"26","author":"R Bilan","year":"2015","unstructured":"Bilan R, Fleury F, Nabiev I, Sukhanova A (2015) Quantum dot surface chemistry and functionalization for cell targeting and imaging. Bioconjug Chem 26:609\u2013624. https:\/\/doi.org\/10.1021\/acs.bioconjchem.5b00069","journal-title":"Bioconjug Chem"},{"key":"3964_CR27","doi-asserted-by":"publisher","first-page":"14215","DOI":"10.1021\/am503517s","volume":"6","author":"M Ren","year":"2014","unstructured":"Ren M, Xu H, Huang X, Kuang M, Xiong Y, Xu H, Xu Y, Chen H, Wang A (2014) Immunoassay for ultrasensitive detection of Aflatoxin B1 in Maizi by highly luminescent quantum dot beads. ACS Appl Mater Interfaces 6:14215\u201314222. https:\/\/doi.org\/10.1021\/am503517s","journal-title":"ACS Appl Mater Interfaces"},{"key":"3964_CR28","doi-asserted-by":"publisher","first-page":"307","DOI":"10.7150\/thno.8007","volume":"4","author":"P Zhang","year":"2014","unstructured":"Zhang P, Lu H, Chen J, Han H, Ma W (2014) Simple and sensitive detection of HBsAg by using a quantum dots Nanobeads based dot-blot immunoassay. Theranostics 4:307\u2013315. https:\/\/doi.org\/10.7150\/thno.8007","journal-title":"Theranostics"},{"issue":"15","key":"3964_CR29","doi-asserted-by":"publisher","first-page":"9530","DOI":"10.1021\/acs.analchem.9b00673","volume":"91","author":"ZW Qie","year":"2019","unstructured":"Qie ZW, Liu QQ, Yan WL, Gao ZC, Meng W, Xiao R, Wang SQ (2019) Universal and ultrasensitive Immunochromatographic assay by using an antigen as a Bifunctional element and Antialbumin antibody on a test line. Anal Chem 91(15):9530\u20139537. https:\/\/doi.org\/10.1021\/acs.analchem.9b00673","journal-title":"Anal Chem"},{"key":"3964_CR30","doi-asserted-by":"publisher","first-page":"625","DOI":"10.1007\/s12161-018-1392-x","volume":"12","author":"D He","year":"2019","unstructured":"He D, Wu Z, Cui B, Xu E, Jin Z (2019) Building a fluorescent Aptasensor based on exonuclease-assisted target recycling strategy for one-step detection of T-2 toxin. Food Anal Methods 12:625\u2013632. https:\/\/doi.org\/10.1007\/s12161-018-1392-x","journal-title":"Food Anal Methods"},{"key":"3964_CR31","doi-asserted-by":"publisher","first-page":"725","DOI":"10.1016\/j.foodcont.2013.06.021","volume":"34","author":"C Li","year":"2013","unstructured":"Li C, Luo W, Xu H, Zhang Q, Xu H, Aguilar ZP, Lai W, Wei H, Xiong Y (2013) Development of an immunoassay for rapid and quantitative detection of Clenbuterol in swine urine. Food Control 34:725\u2013732. https:\/\/doi.org\/10.1016\/j.foodcont.2013.06.021","journal-title":"Food Control"},{"key":"3964_CR32","doi-asserted-by":"publisher","first-page":"97","DOI":"10.1016\/j.jim.2011.12.002","volume":"376","author":"V Semenova","year":"2012","unstructured":"Semenova V, Schiffer J, Steward-Clark E, Soroka S, Schmidt D, Brawner M, Lyde F, Thompson R, Brown N, Foster L (2012) Validation and long term performance characteristics of a quantitative enzyme linked Immunosorbent assay (ELISA) for human anti-PA IgG. J Immunol Methods 376:97\u2013107. https:\/\/doi.org\/10.1016\/j.jim.2011.12.002","journal-title":"J Immunol Methods"},{"key":"3964_CR33","doi-asserted-by":"publisher","first-page":"11618","DOI":"10.1021\/jf3036066","volume":"60","author":"Y Bai","year":"2012","unstructured":"Bai Y, Liu Z, Bi Y, Wang X, Jin Y, Sun L, Wang H, Zhang C, Xu S (2012) Preparation of polyclonal antibodies and development of a direct competitive enzyme-linked Immunosorbent assay to detect residues of Phenylethanolamine a in urine samples. J Agric Food Chem 60:11618\u201311624. https:\/\/doi.org\/10.1021\/jf3036066","journal-title":"J Agric Food Chem"},{"issue":"5709","key":"3964_CR34","doi-asserted-by":"publisher","first-page":"538","DOI":"10.1126\/science.1104274","volume":"307","author":"X Michalet","year":"2005","unstructured":"Michalet X, Pinaud FF, Bentolila LA, Tsay JM, Doose S, Li JJ, Sundaresan G, Wu AM, Gambhir SS, Weiss S (2005) Quantum dots for live cells, in vivo imaging, and diagnostic. Science. 307(5709):538\u2013544. https:\/\/doi.org\/10.1126\/science.1104274","journal-title":"Science."}],"container-title":["Microchimica Acta"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00604-019-3964-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00604-019-3964-x\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00604-019-3964-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,11,18]],"date-time":"2020-11-18T19:58:01Z","timestamp":1605729481000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00604-019-3964-x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,11,20]]},"references-count":34,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2019,12]]}},"alternative-id":["3964"],"URL":"https:\/\/doi.org\/10.1007\/s00604-019-3964-x","relation":{},"ISSN":["0026-3672","1436-5073"],"issn-type":[{"value":"0026-3672","type":"print"},{"value":"1436-5073","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,11,20]]},"assertion":[{"value":"26 June 2019","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"18 October 2019","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"20 November 2019","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}],"article-number":"816"}}