{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T19:57:56Z","timestamp":1789588676979,"version":"build-2803163510"},"reference-count":35,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2021,12,7]],"date-time":"2021-12-07T00:00:00Z","timestamp":1638835200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2021,12,7]],"date-time":"2021-12-07T00:00:00Z","timestamp":1638835200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"funder":[{"name":"Postdoctoral Fund of Hebei Medical University"},{"name":"Postdoctoral Fund of Hebei Province","award":["B2021003040"],"award-info":[{"award-number":["B2021003040"]}]},{"DOI":"10.13039\/501100003787","name":"Natural Science Foundation of Hebei Province","doi-asserted-by":"publisher","award":["B2021206005"],"award-info":[{"award-number":["B2021206005"]}],"id":[{"id":"10.13039\/501100003787","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003787","name":"Natural Science Foundation of Hebei Province","doi-asserted-by":"publisher","award":["H2020206416"],"award-info":[{"award-number":["H2020206416"]}],"id":[{"id":"10.13039\/501100003787","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003787","name":"Natural Science Foundation of Hebei Province","doi-asserted-by":"publisher","award":["B2019206437"],"award-info":[{"award-number":["B2019206437"]}],"id":[{"id":"10.13039\/501100003787","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Youth Top Talent Project of Hebei Province Higher Education","award":["BJ2021050"],"award-info":[{"award-number":["BJ2021050"]}]},{"name":"Youth Top Talent Project of Hebei Province Higher Education","award":["BJ2020034"],"award-info":[{"award-number":["BJ2020034"]}]},{"name":"Chunyu Project Outstanding Youth Fund of Hebei Medical University","award":["CYYQ2021003"],"award-info":[{"award-number":["CYYQ2021003"]}]},{"name":"Chunyu Project Outstanding Youth Fund of Hebei Medical University","award":["CYYQ201903"],"award-info":[{"award-number":["CYYQ201903"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Microchim Acta"],"published-print":{"date-parts":[[2022,1]]},"DOI":"10.1007\/s00604-021-05119-y","type":"journal-article","created":{"date-parts":[[2021,12,7]],"date-time":"2021-12-07T02:02:27Z","timestamp":1638842547000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Fluorescence-active and peroxidase-like expanded mesoporous silica-encapsulated ultrasmall Pt nanoclusters: a novel colorimetric\/fluorescent dual-mode nanosensor for sensitive detection of mercury in medicinal and edible Pueraria lobata"],"prefix":"10.1007","volume":"189","author":[{"given":"Yanting","family":"Shen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuhui","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yanyan","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2021,12,7]]},"reference":[{"issue":"5","key":"5119_CR1","doi-asserted-by":"publisher","first-page":"3433","DOI":"10.1021\/cr100383r","volume":"111","author":"G Aragay","year":"2011","unstructured":"Aragay G, Pons J, Merko\u00e7i A (2011) Recent trends in macro-, micro-, and nanomaterial-based tools and strategies for heavy-metal detection. Chem Rev 111(5):3433\u20133458","journal-title":"Chem Rev"},{"issue":"5","key":"5119_CR2","doi-asserted-by":"publisher","first-page":"483","DOI":"10.1177\/074823379901500504","volume":"15","author":"JF Risher","year":"1999","unstructured":"Risher JF, De Rosa CT, Jones DE, Murray HE (1999) Summary report for the expert panel review of the toxicological profile for mercury. Toxicol Ind Health 15(5):483\u2013516","journal-title":"Toxicol Ind Health"},{"issue":"11","key":"5119_CR3","doi-asserted-by":"publisher","first-page":"6851","DOI":"10.1021\/acs.analchem.8b01018","volume":"90","author":"Y-M Lei","year":"2018","unstructured":"Lei Y-M, Wen R-X, Zhou J, Chai Y-Q, Yuan R, Zhuo Y (2018) Silver ions as novel coreaction accelerator for remarkably enhanced electrochemiluminescence in a PTCA\u2013S2O82\u2013system and its application in an ultrasensitive assay for mercury ions. Anal Chem 90(11):6851\u20136858","journal-title":"Anal Chem"},{"issue":"5","key":"5119_CR4","doi-asserted-by":"publisher","first-page":"590","DOI":"10.1289\/ehp.7743","volume":"113","author":"L Trasande","year":"2005","unstructured":"Trasande L, Landrigan PJ, Schechter C (2005) Public health and economic consequences of methyl mercury toxicity to the developing brain. Environ Health Persp 113(5):590\u2013596","journal-title":"Environ Health Persp"},{"issue":"2","key":"5119_CR5","doi-asserted-by":"publisher","first-page":"1250","DOI":"10.1021\/ac503939d","volume":"87","author":"B Sun","year":"2015","unstructured":"Sun B, Jiang X, Wang H, Song B, Zhu Y, Wang H, Su Y, He Y (2015) Surface-enhancement Raman scattering sensing strategy for discriminating trace mercuric ion (II) from real water samples in sensitive, specific, recyclable, and reproducible manners. Anal Chem 87(2):1250\u20131256","journal-title":"Anal Chem"},{"key":"5119_CR6","doi-asserted-by":"publisher","first-page":"733","DOI":"10.1016\/j.talanta.2014.10.019","volume":"132","author":"PdO Vicentino","year":"2015","unstructured":"Vicentino PdO, Brum DM, Cassella RJ (2015) Development of a method for total Hg determination in oil samples by cold vapor atomic absorption spectrometry after its extraction induced by emulsion breaking. Talanta 132:733\u2013738","journal-title":"Talanta"},{"issue":"1","key":"5119_CR7","doi-asserted-by":"publisher","first-page":"514","DOI":"10.1021\/ac403447a","volume":"86","author":"G Sener","year":"2014","unstructured":"Sener G, Uzun L, Denizli A (2014) Lysine-promoted colorimetric response of gold nanoparticles: a simple assay for ultrasensitive mercury (II) detection. Anal Chem 86(1):514\u2013520","journal-title":"Anal Chem"},{"key":"5119_CR8","doi-asserted-by":"publisher","first-page":"213","DOI":"10.1016\/j.talanta.2017.04.068","volume":"171","author":"S Zhu","year":"2017","unstructured":"Zhu S, Chen B, He M, Huang T, Hu B (2017) Speciation of mercury in water and fish samples by HPLC-ICP-MS after magnetic solid phase extraction. Talanta 171:213\u2013219","journal-title":"Talanta"},{"issue":"8","key":"5119_CR9","doi-asserted-by":"publisher","first-page":"4010","DOI":"10.1039\/C7NR07935D","volume":"10","author":"Y Shi","year":"2018","unstructured":"Shi Y, Chen N, Su Y, Wang H, He Y (2018) Silicon nanohybrid-based SERS chips armed with an internal standard for broad-range, sensitive and reproducible simultaneous quantification of lead (II) and mercury (II) in real systems. Nanoscale 10(8):4010\u20134018","journal-title":"Nanoscale"},{"issue":"47","key":"5119_CR10","doi-asserted-by":"publisher","first-page":"21201","DOI":"10.1021\/acs.iecr.9b03622","volume":"58","author":"J Yao","year":"2019","unstructured":"Yao J, He Y, Li L, Li P, Yang M (2019) Magnified fluorescent aptasensors based on a gold nanoparticle\u2212 DNA hybrid and DNase I for the cycling detection of mercury (II) Ions in aqueous solution. Ind Eng Chem Res 58(47):21201\u201321207","journal-title":"Ind Eng Chem Res"},{"issue":"20","key":"5119_CR11","doi-asserted-by":"publisher","first-page":"8165","DOI":"10.1039\/C4AY01183J","volume":"6","author":"SSJ Xavier","year":"2014","unstructured":"Xavier SSJ, Karthikeyan C, Kim AR, Yoo DJ (2014) Colorimetric detection of melamine using \u03b2-cyclodextrin-functionalized silver nanoparticles. Anal Methods 6(20):8165\u20138172","journal-title":"Anal Methods"},{"issue":"41","key":"5119_CR12","doi-asserted-by":"publisher","first-page":"5510","DOI":"10.1002\/smll.201500903","volume":"11","author":"Y Xianyu","year":"2015","unstructured":"Xianyu Y, Xie Y, Wang N, Wang Z, Jiang X (2015) A dispersion-dominated chromogenic strategy for colorimetric sensing of glutathione at the nanomolar level using gold nanoparticles. Small 11(41):5510\u20135514","journal-title":"Small"},{"issue":"21","key":"5119_CR13","doi-asserted-by":"publisher","first-page":"7441","DOI":"10.1021\/ie3003232","volume":"51","author":"CJ Kirubaharan","year":"2012","unstructured":"Kirubaharan CJ, Kalpana D, Lee YS, Kim A, Yoo DJ, Nahm KS, Kumar GG (2012) Biomediated silver nanoparticles for the highly selective copper (II) ion sensor applications. Ind Eng Chem Res 51(21):7441\u20137446","journal-title":"Ind Eng Chem Res"},{"issue":"3","key":"5119_CR14","doi-asserted-by":"publisher","first-page":"631","DOI":"10.1007\/s10895-019-02360-w","volume":"29","author":"SSJ Xavier","year":"2019","unstructured":"Xavier SSJ, Ranjani M, Yoo DJ, Archana V, Charles L, Annaraj J (2019) Environmentally benign carbon nanodots prepared from lemon for the sensitive and selective fluorescence detection of Fe (III) and tannic acid. J Fluoresc 29(3):631\u2013643","journal-title":"J Fluoresc"},{"key":"5119_CR15","doi-asserted-by":"publisher","first-page":"29","DOI":"10.1016\/j.jiec.2015.10.033","volume":"35","author":"K Ramachandran","year":"2016","unstructured":"Ramachandran K, Kalpana D, Sathishkumar Y, Lee YS, Ravichandran K (2016) A facile green synthesis of silver nanoparticles using Piper betle biomass and its catalytic activity toward sensitive and selective nitrite detection. J Ind Eng Chem 35:29\u201335","journal-title":"J Ind Eng Chem"},{"issue":"71","key":"5119_CR16","doi-asserted-by":"publisher","first-page":"57804","DOI":"10.1039\/C5RA08471G","volume":"5","author":"M Ranjani","year":"2015","unstructured":"Ranjani M, Sathishkumar Y, Lee YS, Yoo DJ, Kim AR (2015) Ni\u2013Co alloy nanostructures anchored on mesoporous silica nanoparticles for non-enzymatic glucose sensor applications. RSC Adv 5(71):57804\u201357814","journal-title":"RSC Adv"},{"key":"5119_CR17","doi-asserted-by":"publisher","first-page":"124528","DOI":"10.1016\/j.cej.2020.124528","volume":"390","author":"X Guo","year":"2020","unstructured":"Guo X, Chen F, Wang F, Wu Y, Ying Y, Wen Y, Yang H, Ke Q (2020) Recyclable Raman chip for detection of trace Mercury ions. Chem Eng J 390:124528","journal-title":"Chem Eng J"},{"issue":"9","key":"5119_CR18","doi-asserted-by":"publisher","first-page":"1946","DOI":"10.1002\/pat.4919","volume":"31","author":"DF Katowah","year":"2020","unstructured":"Katowah DF, Alqarni S, Mohammed GI, Al Sheheri SZ, Alam M, Ismail SH, Asiri AM, Hussein MA, Rahman MM (2020) Selective Hg2+ sensor performance based various carbon-nanofillers into CuO-PMMA nanocomposites. Polym Advan Technol 31(9):1946\u20131962","journal-title":"Polym Advan Technol"},{"key":"5119_CR19","doi-asserted-by":"publisher","first-page":"104291","DOI":"10.1016\/j.microc.2019.104291","volume":"152","author":"MM Rahman","year":"2020","unstructured":"Rahman MM, Alamry KA, Awual MR, Mekky AE (2020) Efficient Hg (II) ionic probe development based on one-step synthesized diethyl thieno [2, 3-b] thiophene-2, 5-dicarboxylate (DETTDC2) onto glassy carbon electrode. Microchem J 152:104291","journal-title":"Microchem J"},{"issue":"6","key":"5119_CR20","doi-asserted-by":"publisher","first-page":"065019","DOI":"10.1088\/2053-1591\/aac681","volume":"5","author":"MM Rahman","year":"2018","unstructured":"Rahman MM, Alenazi NA, Hussein MA, Alam M, Alamry KA, Asiri AM (2018) Hybride ZnCdCrO embedded aminated polyethersulfone nanocomposites for the development of Hg2+ ionic sensor. Mater Res Express 5(6):065019","journal-title":"Mater Res Express"},{"issue":"2","key":"5119_CR21","doi-asserted-by":"publisher","first-page":"420","DOI":"10.1021\/acsomega.6b00359","volume":"2","author":"MM Hussain","year":"2017","unstructured":"Hussain MM, Rahman MM, Arshad MN, Asiri AM (2017) Hg2+ sensor development based on (E)-N\u2032-nitrobenzylidene-benzenesulfonohydrazide (NBBSH) derivatives fabricated on a glassy carbon electrode with a nafion matrix. ACS Omega 2(2):420\u2013431","journal-title":"ACS Omega"},{"issue":"2","key":"5119_CR22","doi-asserted-by":"publisher","first-page":"160","DOI":"10.1007\/s10971-012-2920-6","volume":"65","author":"A Khan","year":"2013","unstructured":"Khan A, Asiri AM, Khan AAP, Rub MA, Azum N, Rahman MM, Khan SB, Alamry KA, Ab Ghani S (2013) Sol\u2013gel synthesis and characterization of conducting polythiophene\/tin phosphate nano tetrapod composite cation-exchanger and its application as Hg (II) selective membrane electrode. J Sol-Gel Sci Technol 65(2):160\u2013169","journal-title":"J Sol-Gel Sci Technol"},{"key":"5119_CR23","doi-asserted-by":"publisher","first-page":"243","DOI":"10.1016\/j.cej.2016.01.038","volume":"290","author":"MR Awual","year":"2016","unstructured":"Awual MR, Hasan MM, Eldesoky GE, Khaleque MA, Rahman MM, Naushad M (2016) Facile mercury detection and removal from aqueous media involving ligand impregnated conjugate nanomaterials. Chem Eng J 290:243\u2013251","journal-title":"Chem Eng J"},{"issue":"127","key":"5119_CR24","doi-asserted-by":"publisher","first-page":"105169","DOI":"10.1039\/C5RA17925D","volume":"5","author":"A Khan","year":"2015","unstructured":"Khan A, Khan AAP, Rahman MM, Asiri AM, Alamry KA (2015) Preparation of polyaniline grafted graphene oxide\u2013WO 3 nanocomposite and its application as a chromium (iii) chemi-sensor. RSC Adv 5(127):105169\u2013105178","journal-title":"RSC Adv"},{"key":"5119_CR25","doi-asserted-by":"publisher","first-page":"145","DOI":"10.1016\/j.matchemphys.2019.04.071","volume":"232","author":"C Wang","year":"2019","unstructured":"Wang C, Wang Y, Shi H, Yan Y, Liu E, Hu X, Fan J (2019) A strong blue fluorescent nanoprobe for highly sensitive and selective detection of mercury (II) based on sulfur doped carbon quantum dots. Mater Chem Phys 232:145\u2013151","journal-title":"Mater Chem Phys"},{"issue":"10","key":"5119_CR26","doi-asserted-by":"publisher","first-page":"9408","DOI":"10.1021\/acssuschemeng.9b00613","volume":"7","author":"W-R Cui","year":"2019","unstructured":"Cui W-R, Zhang C-R, Jiang W, Liang R-P, Wen S-H, Peng D, Qiu J-D (2019) Covalent organic framework nanosheet-based ultrasensitive and selective colorimetric sensor for trace Hg2+ detection. ACS Sustain Chem Eng 7(10):9408\u20139415","journal-title":"ACS Sustain Chem Eng"},{"issue":"6","key":"5119_CR27","doi-asserted-by":"publisher","first-page":"1097","DOI":"10.1002\/adma.201405105","volume":"27","author":"Y Tao","year":"2015","unstructured":"Tao Y, Ju E, Ren J, Qu X (2015) Bifunctionalized mesoporous silica-supported gold nanoparticles: intrinsic oxidase and peroxidase catalytic activities for antibacterial applications. Adv Mater 27(6):1097\u20131104","journal-title":"Adv Mater"},{"issue":"20","key":"5119_CR28","doi-asserted-by":"publisher","first-page":"1845","DOI":"10.1002\/adma.200400349","volume":"16","author":"KJ Lin","year":"2004","unstructured":"Lin KJ, Chen LJ, Prasad MR, Cheng CY (2004) Core\u2013shell synthesis of a novel, spherical, mesoporous silica\/platinum nanocomposite: Pt\/PVP@ MCM-41. Adv Mater 16(20):1845\u20131849","journal-title":"Adv Mater"},{"issue":"18","key":"5119_CR29","doi-asserted-by":"publisher","first-page":"3449","DOI":"10.1063\/1.1518158","volume":"81","author":"J Arbiol","year":"2002","unstructured":"Arbiol J, Cabot A, Morante J, Chen F, Liu M (2002) Distributions of noble metal Pd and Pt in mesoporous silica. Appl Phys Lett 81(18):3449\u20133451","journal-title":"Appl Phys Lett"},{"issue":"4","key":"5119_CR30","doi-asserted-by":"publisher","first-page":"2312","DOI":"10.1016\/j.ijhydene.2018.07.161","volume":"44","author":"HA Khan","year":"2019","unstructured":"Khan HA, Iqbal MI, Jaleel A, Abbas I, Abbas SA, Deog-Jung K (2019) Pt encapsulated hollow mesoporous SiO2 sphere catalyst for sulfuric acid decomposition reaction in SI cycle. Int J Hydrogen Energy 44(4):2312\u20132322","journal-title":"Int J Hydrogen Energy"},{"issue":"46","key":"5119_CR31","doi-asserted-by":"publisher","first-page":"40716","DOI":"10.1021\/acsami.7b13695","volume":"9","author":"H Li","year":"2017","unstructured":"Li H, Liu H, Zhang J, Cheng Y, Zhang C, Fei X, Xian Y (2017) Platinum nanoparticle encapsulated metal\u2013organic frameworks for colorimetric measurement and facile removal of mercury (II). ACS Appl Mater Int 9(46):40716\u201340725","journal-title":"ACS Appl Mater Int"},{"key":"5119_CR32","doi-asserted-by":"publisher","first-page":"251","DOI":"10.1016\/j.bios.2014.11.032","volume":"66","author":"W Li","year":"2015","unstructured":"Li W, Chen B, Zhang H, Sun Y, Wang J, Zhang J, Fu Y (2015) BSA-stabilized Pt nanozyme for peroxidase mimetics and its application on colorimetric detection of mercury (II) ions. Biosens Bioelectron 66:251\u2013258","journal-title":"Biosens Bioelectron"},{"key":"5119_CR33","doi-asserted-by":"publisher","first-page":"180","DOI":"10.1016\/j.aca.2020.01.015","volume":"1104","author":"M Li","year":"2020","unstructured":"Li M, Lv J, Wang S, Wang J, Lin Y (2020) Expanded mesoporous silica-encapsulated ultrasmall Pt nanoclusters as artificial enzymes for tracking hydrogen peroxide secretion from live cells. Anal Chim Acta 1104:180\u2013187","journal-title":"Anal Chim Acta"},{"key":"5119_CR34","doi-asserted-by":"crossref","unstructured":"Josephy PD, Eling T, Mason RP (1982) The horseradish peroxidase-catalyzed oxidation of 3, 5, 3', 5'-tetramethylbenzidine. Free radical and charge-transfer complex intermediates. J Biol Chem 257 (7):3669-3675","DOI":"10.1016\/S0021-9258(18)34832-4"},{"issue":"21","key":"5119_CR35","doi-asserted-by":"publisher","first-page":"10955","DOI":"10.1021\/ac503544w","volume":"86","author":"G-W Wu","year":"2014","unstructured":"Wu G-W, He S-B, Peng H-P, Deng H-H, Liu A-L, Lin X-H, Xia X-H, Chen W (2014) Citrate-capped platinum nanoparticle as a smart probe for ultrasensitive mercury sensing. Anal Chem 86(21):10955\u201310960","journal-title":"Anal Chem"}],"container-title":["Microchimica Acta"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00604-021-05119-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00604-021-05119-y\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00604-021-05119-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,1,15]],"date-time":"2022-01-15T16:13:55Z","timestamp":1642263235000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00604-021-05119-y"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,12,7]]},"references-count":35,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2022,1]]}},"alternative-id":["5119"],"URL":"https:\/\/doi.org\/10.1007\/s00604-021-05119-y","relation":{},"ISSN":["0026-3672","1436-5073"],"issn-type":[{"value":"0026-3672","type":"print"},{"value":"1436-5073","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,12,7]]},"assertion":[{"value":"16 August 2021","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"23 November 2021","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"7 December 2021","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}],"article-number":"18"}}