{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T09:07:52Z","timestamp":1791882472942,"version":"4.3.4"},"reference-count":64,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[2024,3,20]],"date-time":"2024-03-20T00:00:00Z","timestamp":1710892800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2024,3,20]],"date-time":"2024-03-20T00:00:00Z","timestamp":1710892800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"DOI":"10.13039\/100020595","name":"National Science and Technology Council","doi-asserted-by":"publisher","award":["NSTC107-2113-M-037-007-MY2"],"award-info":[{"award-number":["NSTC107-2113-M-037-007-MY2"]}],"id":[{"id":"10.13039\/100020595","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Microchim Acta"],"published-print":{"date-parts":[[2024,4]]},"DOI":"10.1007\/s00604-024-06273-9","type":"journal-article","created":{"date-parts":[[2024,3,20]],"date-time":"2024-03-20T19:01:46Z","timestamp":1710961306000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":33,"title":["Highly electrochemically active Ti3C2Tx MXene\/MWCNT nanocomposite for the simultaneous sensing of paracetamol, theophylline, and caffeine in human blood samples"],"prefix":"10.1007","volume":"191","author":[{"given":"Elancheziyan","family":"Mari","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Murugesan","family":"Duraisamy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Muthusankar","family":"Eswaran","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Senthilkumar","family":"Sellappan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keehoon","family":"Won","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pranjal","family":"Chandra","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pei-Chien","family":"Tsai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Po-Chin","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yi-Hsun","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuan-Chung","family":"Lin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vinoth Kumar","family":"Ponnusamy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,3,20]]},"reference":[{"key":"6273_CR1","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1016\/j.sbsr.2017.11.002","volume":"16","author":"B Mekassa","year":"2017","unstructured":"Mekassa B, Tessema M, Chandravanshi BS (2017) Simultaneous determination of caffeine and theophylline using square wave voltammetry at poly (L-aspartic acid)\/functionalized multi-walled carbon nanotubes composite modified electrode. Sens Bio-sens Res 16:46\u201354","journal-title":"Sens Bio-sens Res"},{"key":"6273_CR2","doi-asserted-by":"crossref","first-page":"3207","DOI":"10.1007\/s10008-012-1760-1","volume":"16","author":"X Kan","year":"2012","unstructured":"Kan X, Liu T, Li C, Zhou H, Xing Z, Zhu A (2012) A novel electrochemical sensor based on molecularly imprinted polymers for caffeine recognition and detection. J Solid State Electrochem 16:3207\u20133213","journal-title":"J Solid State Electrochem"},{"key":"6273_CR3","doi-asserted-by":"crossref","first-page":"13017","DOI":"10.1021\/acs.analchem.0c01857","volume":"92","author":"N Wester","year":"2020","unstructured":"Wester N, Mikladal BF, Varjos I, Peltonen A, Kalso E, Lilius T, Laurila T, Koskinen J (2020) Disposable nafion-coated single-walled carbon nanotube test strip for electrochemical quantitative determination of acetaminophen in a finger-prick whole blood sample. Anal Chem 92:13017\u201313024","journal-title":"Anal Chem"},{"key":"6273_CR4","doi-asserted-by":"crossref","first-page":"436","DOI":"10.1016\/j.jpha.2021.08.005","volume":"12","author":"H Yang","year":"2022","unstructured":"Yang H, Cao G, Huang Y, Lin L, Zheng F, Lin L, Liu F, Li S (2022) Nitrogen-doped carbon@TiO2 double-shelled hollow spheres as an electrochemical sensor for simultaneous determination of dopamine and paracetamol in human serum and saliva. J Pharm Anal 12:436\u2013445","journal-title":"J Pharm Anal"},{"key":"6273_CR5","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1016\/j.jpha.2020.11.003","volume":"11","author":"W Boumya","year":"2021","unstructured":"Boumya W, Taoufik N, Achak M, Barka N (2021) Chemically modified carbon-based electrodes for the determination of paracetamol in drugs and biological samples. J Pharm Anal 11:138\u2013154","journal-title":"J Pharm Anal"},{"key":"6273_CR6","doi-asserted-by":"crossref","first-page":"3503","DOI":"10.1039\/c3ay40209f","volume":"5","author":"M Devaraj","year":"2013","unstructured":"Devaraj M, Deivasigamani RK, Jayadevan S (2013) Controlled growth and molecular self-assembly of Au nanoparticles to Au nanochains: application towards enhancement for the electrochemical determination of paracetamol. Anal Methods 5:3503\u20133515","journal-title":"Anal Methods"},{"key":"6273_CR7","doi-asserted-by":"crossref","first-page":"2252","DOI":"10.1021\/acsapm.0c00239","volume":"2","author":"CS Kushwaha","year":"2020","unstructured":"Kushwaha CS, Shukla SK (2020) Electrochemical sensing of paracetamol using iron oxide encapsulated in chitosan-grafted-polyaniline. ACS Appl Poly Mater 2:2252\u20132259","journal-title":"ACS Appl Poly Mater"},{"key":"6273_CR8","doi-asserted-by":"crossref","first-page":"76973","DOI":"10.1039\/C5RA12520K","volume":"5","author":"L Fu","year":"2015","unstructured":"Fu L, Lai G, Yu A (2015) Preparation of \u03b2-cyclodextrin functionalized reduced graphene oxide: application for electrochemical determination of paracetamol. Rsc Adv 5:76973\u201376938","journal-title":"Rsc Adv"},{"key":"6273_CR9","doi-asserted-by":"crossref","first-page":"5634","DOI":"10.1039\/C8AY02150C","volume":"47","author":"W Silva","year":"2018","unstructured":"Silva W, Ghica ME, Brett CM (2018) Gold nanoparticle decorated multiwalled carbon nanotube modified electrodes for the electrochemical determination of theophylline. Anal methods 47:5634\u20135642","journal-title":"Anal methods"},{"key":"6273_CR10","volume":"3","author":"RD Crapnell","year":"2021","unstructured":"Crapnell RD, Banks CE (2021) Electroanalytical overview: the electroanalytical detection of theophylline. Talanta 3:100037","journal-title":"Talanta"},{"key":"6273_CR11","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s00604-018-3127-5","volume":"186","author":"X Hu","year":"2019","unstructured":"Hu X, Xi J, Xia Y, Zhao F, Zeng B (2019) Space-confined synthesis of ordered mesoporous carbon doped with single-layer MoS2\u2013boron for the voltammetric determination of theophylline. Microchim Acta 186:1\u20138","journal-title":"Microchim Acta"},{"key":"6273_CR12","doi-asserted-by":"crossref","DOI":"10.1016\/j.jpba.2020.113663","volume":"192","author":"Y Duan","year":"2021","unstructured":"Duan Y, Wang A, Ding Y, Li L, Duan D, Lin J, Yu C, Liu J (2021) Fabrication of poly-sulfosalicylic acid film decorated pure carbon fiber as electrochemical sensing platform for detection of theophylline. J Pharm Biomed Anal 192:113663","journal-title":"J Pharm Biomed Anal"},{"key":"6273_CR13","doi-asserted-by":"crossref","first-page":"5755","DOI":"10.1016\/S1452-3981(23)14720-1","volume":"8","author":"L Svorc","year":"2013","unstructured":"Svorc L (2013) Determination of caffeine: a comprehensive review on electrochemical methods. Int J Electrochem Sci 8:5755\u20135773","journal-title":"Int J Electrochem Sci"},{"key":"6273_CR14","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1016\/j.snb.2015.05.003","volume":"218","author":"DM Fernandes","year":"2015","unstructured":"Fernandes DM, Silva N, Pereira C, Moura C, Magalhaes JM, Bachiller-Baeza B, Rodriguez-Ramos I, Guerrero-Ruiz A, Delerue-Matos C, Freire C (2015) MnFe2O4@CNT-N as novel electrochemical nanosensor for determination of caffeine, acetaminophen and ascorbic acid. Sens Actuators B: Chem 218:128\u2013136","journal-title":"Sens Actuators B: Chem"},{"key":"6273_CR15","doi-asserted-by":"crossref","first-page":"7937","DOI":"10.1039\/C6AY02804G","volume":"44","author":"S Selvam","year":"2016","unstructured":"Selvam S, Balamuralitharan B, Karthick SN, Hemalatha KV, Prabakar K, Kim HJ (2016) Simultaneous electrochemical deposition of an e-rGO\/\u03b2-CD\/MnO2 ternary composite for a self-powered supercapacitor based caffeine sensor. Anal Methods 44:7937\u20137943","journal-title":"Anal Methods"},{"issue":"4","key":"6273_CR16","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1007\/s00604-022-05222-8","volume":"189","author":"M Wen","year":"2022","unstructured":"Wen M, Xing Y, Liu G, Hou S, Hou S (2022) Electrochemical sensor based on Ti3C2 membrane doped with UIO-66-NH2 for dopamine. Microchim Acta 189(4):141","journal-title":"Microchim Acta"},{"issue":"40","key":"6273_CR17","doi-asserted-by":"crossref","first-page":"35486","DOI":"10.1021\/acsomega.1c07306","volume":"7","author":"M Eagambaram","year":"2022","unstructured":"Eagambaram M, Kumar K (2022) Design of an efficient tin selenide-based ternary nanocomposite electrode for simultaneous determination of paracetamol, tryptophan, and caffeine. ACS Omega 7(40):35486\u201335495","journal-title":"ACS Omega"},{"key":"6273_CR18","doi-asserted-by":"crossref","DOI":"10.1016\/j.saa.2020.118801","volume":"243","author":"K Palur","year":"2020","unstructured":"Palur K, Archakam SC, Koganti B (2020) Chemometric assisted UV spectrophotometric and RP-HPLC methods for simultaneous determination of paracetamol, diphenhydramine, caffeine and phenylephrine in tablet dosage form. Spectrochim Acta-A: Mol Biomol 243:118801","journal-title":"Spectrochim Acta-A: Mol Biomol"},{"key":"6273_CR19","doi-asserted-by":"crossref","first-page":"47114","DOI":"10.1039\/C4RA06412G","volume":"87","author":"H Sereshti","year":"2014","unstructured":"Sereshti H, Khosraviani M, Samadi S, Amini-Fazl MS (2014) Simultaneous determination of theophylline, theobromine and caffeine in different tea beverages by graphene-oxide based ultrasonic-assisted dispersive micro solid-phase extraction combined with HPLC-UV. RSC Adv 87:47114\u201324710","journal-title":"RSC Adv"},{"key":"6273_CR20","doi-asserted-by":"crossref","first-page":"591","DOI":"10.1016\/j.arabjc.2013.09.040","volume":"8","author":"AP Dewani","year":"2015","unstructured":"Dewani AP, Dabhade SM, Bakal RL, Gadewar CK, Chandewar AV, Patra S (2015) Development and validation of a novel RP-HPLC method for simultaneous determination of paracetamol, phenylephrine hydrochloride, caffeine, cetirizine and nimesulide in tablet formulation. Arab J Chem 8:591\u2013598","journal-title":"Arab J Chem"},{"key":"6273_CR21","doi-asserted-by":"crossref","first-page":"5667","DOI":"10.1021\/acs.analchem.8b05531","volume":"91","author":"E Murugan","year":"2019","unstructured":"Murugan E, Kumar K (2019) Fabrication of SnS\/TiO2@GO composite coated glassy carbon electrode for concomitant determination of paracetamol, tryptophan, and caffeine in pharmaceutical formulations. Anal Chem 91:5667\u20135676","journal-title":"Anal Chem"},{"key":"6273_CR22","doi-asserted-by":"crossref","first-page":"1095","DOI":"10.1016\/j.jpba.2006.01.062","volume":"41","author":"C Barbas Arribas","year":"2006","unstructured":"Barbas Arribas C, Alguacil Merino LF (2006) Capillary electrophoresis for caffeine and pyroglutamate determination in coffees. J Pharm Biomed Anal 41:1095\u20131100","journal-title":"J Pharm Biomed Anal"},{"issue":"5","key":"6273_CR23","doi-asserted-by":"crossref","first-page":"4251","DOI":"10.20964\/2017.05.37","volume":"12","author":"X Shu","year":"2017","unstructured":"Shu X, Bian F, Wang Q, Qin X, Wang Y (2017) Electrochemical sensor for simultaneous determination of theophylline and caffeine based on a novel poly (folic acid)\/graphene composite film modified electrode. Int J Electrochem Sci 12(5):4251\u20134264","journal-title":"Int J Electrochem Sci"},{"key":"6273_CR24","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1016\/j.jelechem.2013.07.030","volume":"706","author":"Y Gao","year":"2013","unstructured":"Gao Y, Wang H, Guo L (2013) Simultaneous determination of theophylline and caffeine by large mesoporous carbon\/Nafion modified electrode. J Electroanal Chem 706:7\u201312","journal-title":"J Electroanal Chem"},{"key":"6273_CR25","doi-asserted-by":"publisher","unstructured":"Ray SC, Jana NR (2017) Carbon nanomaterials for biological and medical applications. Chapter 3 - application of carbon-based nanomaterials as biosensor pp 87\u2013127. https:\/\/doi.org\/10.1016\/B978-0-323-47906-6.00003-5","DOI":"10.1016\/B978-0-323-47906-6.00003-5"},{"key":"6273_CR26","doi-asserted-by":"crossref","first-page":"11662","DOI":"10.1038\/s41598-021-89427-6","volume":"11","author":"J Jose","year":"2021","unstructured":"Jose J, Subramanian V, Shaji S, Sreeja PB (2021) An electrochemical sensor for nanomolar detection of caffeine based on nicotinic acid hydrazide anchored on graphene oxide (NAHGO). Sci Rep 11:11662","journal-title":"Sci Rep"},{"key":"6273_CR27","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1016\/j.snb.2014.02.096","volume":"197","author":"S Tajik","year":"2014","unstructured":"Tajik S, Taher MA, Beitollahi H (2014) Application of a new ferrocene-derivative modified-graphene paste electrode for simultaneous determination of isoproterenol, acetaminophen and theophylline. Sens Actuators B: Chem 197:228\u2013236","journal-title":"Sens Actuators B: Chem"},{"key":"6273_CR28","doi-asserted-by":"crossref","DOI":"10.1016\/j.diamond.2022.109268","volume":"128","author":"E Murugan","year":"2022","unstructured":"Murugan E, Dhamodharan A (2022) MoS2\/PANI\/f-MWCNTs ternary nanocomposite modified electrode for selective and concomitant sensing of vanillin, theophylline and caffeine. Diam Relat Mater 128:109268","journal-title":"Diam Relat Mater"},{"key":"6273_CR29","doi-asserted-by":"crossref","DOI":"10.1016\/j.chemosphere.2022.135182","volume":"304","author":"H Kaur","year":"2022","unstructured":"Kaur H, Siwal SS, Chauhan G, Saini AK, Kumari A, Thakur VK (2022) Recent advances in electrochemical-based sensors amplified with carbon-based nanomaterials (CNMs) for sensing pharmaceutical and food pollutants. Chemosphere 304:135182","journal-title":"Chemosphere"},{"key":"6273_CR30","doi-asserted-by":"crossref","DOI":"10.1016\/j.mseb.2021.115473","volume":"274","author":"R Hallaj","year":"2021","unstructured":"Hallaj R, Soltani E, Mafakheri S, Ghadermazi M (2021) A surface-modified silicon carbide nanoparticles based electrochemical sensor for free interferences determination of caffeine in tea and coffee. Mater Sci Eng 274:115473","journal-title":"Mater Sci Eng"},{"key":"6273_CR31","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s00604-020-04366-9","volume":"187","author":"PK Kalambate","year":"2020","unstructured":"Kalambate PK, Dhanjai SA, Li Y, Shen Y, Huang Y (2020) An electrochemical sensor for ifosfamide, acetaminophen, domperidone, and sumatriptan based on self-assembled MXene\/MWCNT\/chitosan nanocomposite thin film. Microchim Acta 187:1\u201312","journal-title":"Microchim Acta"},{"key":"6273_CR32","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1016\/j.trac.2018.08.023","volume":"108","author":"H Montaseri","year":"2018","unstructured":"Montaseri H, Forbes PB (2018) Analytical techniques for the determination of acetaminophen. Trends Analyt Chem 108:122\u2013134","journal-title":"Trends Anal Chem"},{"issue":"2","key":"6273_CR33","doi-asserted-by":"crossref","first-page":"345","DOI":"10.3390\/nano13020345","volume":"13","author":"F Mohajer","year":"2023","unstructured":"Mohajer F, Ziarani GM, Badiei A, Iravani S, Varma RS (2023) MXene-carbon nanotube composites: properties and applications. Nanomaterials 13(2):345","journal-title":"Nanomaterials"},{"key":"6273_CR34","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s00604-021-04744-x","volume":"188","author":"Q Guan","year":"2021","unstructured":"Guan Q, Guo H, Xue R, Wang M, Wu N, Cao Y, Zhao X, Yang W (2021) Electrochemical sensing platform based on covalent organic framework materials and gold nanoparticles for high sensitivity determination of theophylline and caffeine. Microchim Acta 188:1\u201311","journal-title":"Microchim Acta"},{"issue":"1","key":"6273_CR35","doi-asserted-by":"crossref","first-page":"3223","DOI":"10.1038\/s41467-022-30648-2","volume":"13","author":"Y Shao","year":"2022","unstructured":"Shao Y, Wei L, Wu X, Jiang C, Yao Y, Peng B, Chen H, Huangfu J, Ying Y, Zhang CJ, Ping J (2022) Room-temperature high-precision printing of flexible wireless electronics based on MXene inks. Nat Commun 13(1):3223","journal-title":"Nat Commun"},{"key":"6273_CR36","doi-asserted-by":"crossref","DOI":"10.1016\/j.fuel.2021.121329","volume":"303","author":"M Elancheziyan","year":"2021","unstructured":"Elancheziyan M, Eswaran M, Shuck CE, Senthilkumar S, Elumalai S, Dhanusuraman R, Ponnusamy VK (2021) Facile synthesis of polyaniline\/titanium carbide (MXene) nanosheets\/palladium nanocomposite for efficient electrocatalytic oxidation of methanol for fuel cell application. Fuel 303:121329","journal-title":"Fuel"},{"key":"6273_CR37","doi-asserted-by":"crossref","DOI":"10.1016\/j.est.2023.108414","volume":"72","author":"P Nikhil","year":"2023","unstructured":"Nikhil P, Vasanth S, Ponpandian N, Viswanathan C (2023) Synthesis effect on surface functionalized Ti3C2Tx MXene supported nickel oxide nanocomposites with enhanced specific capacity for supercapacitor application. J Energy Storage 72:108414","journal-title":"J Energy Storage"},{"key":"6273_CR38","doi-asserted-by":"crossref","first-page":"848","DOI":"10.1080\/10408347.2020.1836470","volume":"52","author":"F Shahzad","year":"2022","unstructured":"Shahzad F, Zaidi SA, Naqvi RA (2022) 2D transition metal carbides (MXene) for electrochemical sensing: A review. Crit Rev Anal Chem 52:848\u2013864","journal-title":"Crit Rev Anal Chem"},{"key":"6273_CR39","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1039\/C9NH00571D","volume":"5","author":"X Zhan","year":"2020","unstructured":"Zhan X, Si C, Zhou J, Sun Z (2020) MXene and MXene-based composites: synthesis, properties and environment-related applications. Nanoscale Horiz 5:235\u2013258","journal-title":"Nanoscale Horiz"},{"key":"6273_CR40","doi-asserted-by":"crossref","first-page":"849","DOI":"10.1016\/j.snb.2016.06.164","volume":"237","author":"M Bilgi","year":"2016","unstructured":"Bilgi M, Ayranci E (2016) Biosensor application of screen-printed carbon electrodes modified with nanomaterials and a conducting polymer: ethanol biosensors based on alcohol dehydrogenase. Sens Actuators, B Chem 237:849\u2013855","journal-title":"Sens Actuators, B Chem"},{"key":"6273_CR41","doi-asserted-by":"crossref","first-page":"36","DOI":"10.3390\/nano13010036","volume":"13","author":"M Amin","year":"2023","unstructured":"Amin M, Abdullah BM, Wylie SR, Rowley-Neale SJ, Banks CE, Whitehead KA (2023) The voltammetric detection of cadaverine using a diamine oxidase and multi-walled carbon nanotube functionalised electrochemical biosensor. Nanomaterials 13:36","journal-title":"Nanomaterials"},{"key":"6273_CR42","doi-asserted-by":"crossref","first-page":"544","DOI":"10.1016\/j.chempr.2020.02.013","volume":"6","author":"X Zhao","year":"2020","unstructured":"Zhao X, Radovic M, Green MJ (2020) Synthesizing mxene nanosheets by water-free etching. Chem 6:544\u2013546","journal-title":"Chem"},{"key":"6273_CR43","doi-asserted-by":"crossref","first-page":"9610","DOI":"10.1021\/jacs.9b02578","volume":"141","author":"SY Pang","year":"2019","unstructured":"Pang SY, Wong YT, Yuan S, Liu Y, Tsang MK, Yang Z, Huang H, Wong WT, Hao J (2019) Universal strategy for hf-free facile and rapid synthesis of two-dimensional mxenes as multifunctional energy materials. J Am Chem Soc 141:9610\u20139616","journal-title":"J Am Chem Soc"},{"key":"6273_CR44","doi-asserted-by":"crossref","first-page":"1195","DOI":"10.1016\/j.ceramint.2022.09.097","volume":"49","author":"K Ram Kumar","year":"2023","unstructured":"Ram Kumar K, Maiyalagan T (2023) Iron nickel sulphide embedded on multi-walled carbon nanotubes as efficient electrocatalysts for oxygen evolution reaction in alkaline medium. Ceram Int 49:1195\u20131202","journal-title":"Ceram Int"},{"key":"6273_CR45","doi-asserted-by":"crossref","first-page":"10058","DOI":"10.1021\/acsnano.1c01727","volume":"15","author":"T Yun","year":"2021","unstructured":"Yun T, Lee GS, Choi J, Kim H, Yang GG, Lee HJ, Kim JG, Lee HM, Koo CM, Lim J, Kim SO (2021) Multidimensional Ti3C2Tx mxene architectures via interfacial electrochemical self-assembly. ACS Nano 15:10058\u201310066","journal-title":"ACS Nano"},{"key":"6273_CR46","doi-asserted-by":"crossref","first-page":"3231","DOI":"10.1039\/D0TA11103A","volume":"9","author":"MM Hasan","year":"2021","unstructured":"Hasan MM, Hossain MM, Chowdhury HK (2021) Two-dimensional mxene-based flexible nanostructures for functional nanodevices: a review. J Mater Chem A 9:3231\u20133269","journal-title":"J Mater Chem A"},{"key":"6273_CR47","doi-asserted-by":"crossref","DOI":"10.1016\/j.molliq.2020.115131","volume":"325","author":"M Elancheziyan","year":"2021","unstructured":"Elancheziyan M, Senthilkumar S (2021) Redox-active gold nanoparticle-encapsulated poly (amidoamine) dendrimer for electrochemical sensing of 4-aminophenol. J Mole Liquids 325:115131","journal-title":"J Mol Liq"},{"key":"6273_CR48","volume":"267","author":"N Aschemacher","year":"2023","unstructured":"Aschemacher N, Gegenschatz S, Teglia CM, Siano AS, Gutierrez FA, Goicoechea HC (2023) Highly sensitive and selective electrochemical sensor for simultaneous determination of gallic acid, theophylline and caffeine using poly (l-proline) decorated carbon nanotubes in biological and food samples. Talanta 267:125246","journal-title":"Talanta"},{"key":"6273_CR49","doi-asserted-by":"crossref","first-page":"5148","DOI":"10.1021\/acsanm.8b01217","volume":"9","author":"AR Rajamani","year":"2018","unstructured":"Rajamani AR, Peter SC (2018) Novel nanostructured Pt\/CeO2@Cu2O carbon-based electrode to magnify the electrochemical detection of the neurotransmitter dopamine and analgesic paracetamol. ACS Appl Nano Mater 9:5148\u20135157","journal-title":"ACS Appl Nano Mater"},{"key":"6273_CR50","doi-asserted-by":"crossref","first-page":"21028","DOI":"10.1021\/acsami.6b05440","volume":"32","author":"J Luo","year":"2016","unstructured":"Luo J, Ma Q, Wei W, Zhu Y, Liu R, Liu X (2016) Synthesis of water-dispersible molecularly imprinted electroactive nanoparticles for the sensitive and selective paracetamol detection. ACS Appl Mater Interfaces 32:21028\u201321038","journal-title":"ACS Appl Mater Interfaces"},{"key":"6273_CR51","doi-asserted-by":"crossref","first-page":"314","DOI":"10.1016\/j.snb.2010.02.024","volume":"146","author":"ZA Alothman","year":"2010","unstructured":"Alothman ZA, Bukhari N, Wabaidur SM, Haider S (2010) Simultaneous electrochemical determination of dopamine and acetaminophen using multiwall carbon nanotubes modified glassy carbon electrode. Sens Actuators B Chem 146:314\u2013320","journal-title":"Sens Actuators B Chem"},{"key":"6273_CR52","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1016\/j.talanta.2013.08.041","volume":"117","author":"S Cheemalapati","year":"2013","unstructured":"Cheemalapati S, Palanisamy S, Mani V, Chen SM (2013) Simultaneous electrochemical determination of dopamine and paracetamol on multiwalled carbon nanotubes\/graphene oxide nanocomposite-modified glassy carbon electrode. Talanta 117:297\u2013304","journal-title":"Talanta"},{"key":"6273_CR53","doi-asserted-by":"crossref","first-page":"754","DOI":"10.1016\/j.talanta.2010.01.009","volume":"81","author":"X Kang","year":"2010","unstructured":"Kang X, Wang J, Wu H, Liu J, Aksay IA, Lin Y (2010) A graphene-based electrochemical sensor for sensitive detection of paracetamol. Talanta 81:754\u2013759","journal-title":"Talanta"},{"key":"6273_CR54","volume":"185","author":"Y Zhao","year":"2023","unstructured":"Zhao Y, Xia Y, Zhang J, Liu H, Yi Y, Zhu G (2023) Ag-Ti3C2Tx MXenes nanoribbons coupled with carbon nanotubes: preparation, characterization and application for highly sensitive ratiometric voltammetric sensing of paracetamol. Microchem J 185:108207","journal-title":"Microchem J"},{"key":"6273_CR55","volume":"175","author":"D Liao","year":"2022","unstructured":"Liao D, Liu Z, Huang R, Yu J, Jiang X (2022) In-situ construction of porous carbon on embedded N-doped MXene nanosheets composite for simultaneous determination of 4-aminophenol and acetaminophen. Microchem J 175:107067","journal-title":"Microchem J"},{"key":"6273_CR56","doi-asserted-by":"crossref","DOI":"10.1016\/j.microc.2019.104005","volume":"149","author":"SA Rezvani","year":"2019","unstructured":"Rezvani SA, Soleymanpour A (2019) Application of a sensitive electrochemical sensor modified with WO3 nanoparticles for the trace determination of theophylline. Microchem J 149:104005","journal-title":"Microchem J"},{"key":"6273_CR57","doi-asserted-by":"crossref","first-page":"330","DOI":"10.20964\/2017.01.03","volume":"12","author":"A Peng","year":"2017","unstructured":"Peng A, Yan H, Luo C, Wang G, Wang Y, Ye X, Ding H (2017) Electrochemical determination of theophylline pharmacokinetic under the effect of roxithromycin in rats by the MWNTs\/Au\/poly-L-lysine modified sensor. I J Electrochem Sci 12:330\u2013346","journal-title":"I J Electrochem Sci"},{"key":"6273_CR58","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1016\/j.talanta.2017.08.076","volume":"178","author":"Y Wang","year":"2018","unstructured":"Wang Y, Ding Y, Li L, Hu P (2018) Nitrogen-doped carbon nanotubes decorated poly (L-Cysteine) as a novel, ultrasensitive electrochemical sensor for simultaneous determination of theophylline and caffeine. Talanta 178:449\u2013457","journal-title":"Talanta"},{"key":"6273_CR59","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1016\/j.jelechem.2005.05.004","volume":"581","author":"YH Zhu","year":"2005","unstructured":"Zhu YH, Zhang ZL, Pang DW (2005) Electrochemical oxidation of theophylline at multi-wall carbon nanotube modified glassy carbon electrodes. J Electroanal Chem 581:303\u2013309","journal-title":"J Electroanal Chem"},{"key":"6273_CR60","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.colsurfb.2012.04.010","volume":"97","author":"SJ Malode","year":"2012","unstructured":"Malode SJ, Shetti NP, Nandibewoor ST (2012) Voltammetric behavior of theophylline and its determination at multi-wall carbon nanotube paste electrode. Colloids Surf B 97:1\u20136","journal-title":"Colloids Surf B"},{"key":"6273_CR61","doi-asserted-by":"crossref","first-page":"2552","DOI":"10.20964\/2017.03.02","volume":"12","author":"Y Zhang","year":"2017","unstructured":"Zhang Y, Shang J, Jiang B, Zhou X, Wang J (2017) Electrochemical determination of caffeine in oolong tea based on polyelectrolyte functionalized multi-walled carbon nanotube. Int J Electrochem Sci 12:2552\u20132562","journal-title":"Int J Electrochem Sci"},{"key":"6273_CR62","doi-asserted-by":"crossref","first-page":"1783","DOI":"10.1016\/S1872-2067(11)60438-5","volume":"33","author":"B Habibi","year":"2012","unstructured":"Habibi B, Abazari M, Pournaghi-Azar MH (2012) A carbon nanotube modified electrode for determination of caffeine by differential pulse voltammetry. Chin J Catal 33:1783\u20131790","journal-title":"Chin J Catal"},{"key":"6273_CR63","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/j.jelechem.2009.11.025","volume":"639","author":"S Yang","year":"2010","unstructured":"Yang S, Yang R, Li G, Qu L, Li J, Yu L (2010) Nafion\/multi-wall carbon nanotubes composite film coated glassy carbon electrode for sensitive determination of caffeine. J Electroanal Chem 639:77\u201382","journal-title":"J Electroanal Chem"},{"key":"6273_CR64","doi-asserted-by":"crossref","first-page":"997","DOI":"10.1016\/S1452-3981(23)15050-4","volume":"6","author":"J Zhang","year":"2011","unstructured":"Zhang J, Wang LP, Guo W, Peng XD, Li M, Yuan ZB (2011) Sensitive differential pulse stripping voltammetry of caffeine in medicines and cola using a sensor based on multi-walled carbon nanotubes and nafion. Internat J electrochem Sci 6:997\u20131006","journal-title":"Internat J electrochem Sci"}],"container-title":["Microchimica Acta"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00604-024-06273-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00604-024-06273-9\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00604-024-06273-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,4,8]],"date-time":"2024-04-08T07:09:58Z","timestamp":1712560198000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00604-024-06273-9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,3,20]]},"references-count":64,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2024,4]]}},"alternative-id":["6273"],"URL":"https:\/\/doi.org\/10.1007\/s00604-024-06273-9","relation":{},"ISSN":["0026-3672","1436-5073"],"issn-type":[{"value":"0026-3672","type":"print"},{"value":"1436-5073","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,3,20]]},"assertion":[{"value":"20 November 2023","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"22 February 2024","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"20 March 2024","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"This research did not involve human or animal samples.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"The authors declare no competing interests.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}],"article-number":"212"}}