{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,24]],"date-time":"2026-01-24T12:52:09Z","timestamp":1769259129448,"version":"3.49.0"},"reference-count":29,"publisher":"Springer Science and Business Media LLC","issue":"7","license":[{"start":{"date-parts":[[2024,6,20]],"date-time":"2024-06-20T00:00:00Z","timestamp":1718841600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2024,6,20]],"date-time":"2024-06-20T00:00:00Z","timestamp":1718841600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"name":"DST sponsored Indo-Sri Lanka project","award":["DST\/INT\/SL\/P-30\/2021"],"award-info":[{"award-number":["DST\/INT\/SL\/P-30\/2021"]}]},{"name":"MHRD-RUSA 2.0","award":["F.24-51\/2014-U"],"award-info":[{"award-number":["F.24-51\/2014-U"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Microchim Acta"],"published-print":{"date-parts":[[2024,7]]},"DOI":"10.1007\/s00604-024-06473-3","type":"journal-article","created":{"date-parts":[[2024,6,20]],"date-time":"2024-06-20T03:36:53Z","timestamp":1718854613000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Binder-free and efficient voltammetric sensor based on Zn-Ca2CuO3 nanoparticles for simultaneous determination of amlodipine, acetaminophen, and ascorbic acid in hypertension patients"],"prefix":"10.1007","volume":"191","author":[{"given":"G.","family":"Veerapandi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7109-8226","authenticated-orcid":false,"given":"C.","family":"Sekar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2024,6,20]]},"reference":[{"key":"6473_CR1","doi-asserted-by":"publisher","first-page":"7","DOI":"10.1016\/j.jelechem.2017.01.055","volume":"788","author":"N Jadon","year":"2017","unstructured":"Jadon N, Jain R, Pandey A (2017) Electrochemical analysis of amlodipine in some pharmaceutical formulations and biological fluid using disposable pencil graphite electrode. J Electroanal Chem 788:7\u201313. https:\/\/doi.org\/10.1016\/j.jelechem.2017.01.055","journal-title":"J Electroanal Chem"},{"key":"6473_CR2","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1007\/s42452-020-2807-z","volume":"2","author":"GA Naikoo","year":"2020","unstructured":"Naikoo GA, Pandit UJ, Sheikh MUD et al (2020) Synergistic effect of carbon nanotubes, copper and silver nanoparticles as an efficient electrochemical sensor for the trace recognition of amlodipine besylate drug. SN Appl Sci 2:1\u201312. https:\/\/doi.org\/10.1007\/s42452-020-2807-z","journal-title":"SN Appl Sci"},{"key":"6473_CR3","doi-asserted-by":"publisher","unstructured":"Firouzi M, Giahi M, Najafi M et al (2020) Electrochemical determination of amlodipine using a CuO-NiO nanocomposite\/ionic liquid modified carbon paste electrode as an electrochemical sensor. J Nanoparticle Res 23. https:\/\/doi.org\/10.1007\/s11051-021-05200-w","DOI":"10.1007\/s11051-021-05200-w"},{"key":"6473_CR4","doi-asserted-by":"publisher","first-page":"448","DOI":"10.1002\/elan.201800577","volume":"31","author":"NF Atta","year":"2019","unstructured":"Atta NF, El-Ads EH, Galal A, Galal AE (2019) Electrochemical sensing platform based on nano-perovskite\/glycine\/carbon composite for amlodipine and ascorbic acid drugs. Electroanalysis 31:448\u2013460. https:\/\/doi.org\/10.1002\/elan.201800577","journal-title":"Electroanalysis"},{"key":"6473_CR5","doi-asserted-by":"publisher","first-page":"106138","DOI":"10.1016\/j.microc.2021.106138","volume":"165","author":"K Sudha","year":"2021","unstructured":"Sudha K, Elangovan A, Jeevika A et al (2021) Electroanalytical detection of amlodipine in urine and pharmaceutical samples using Ag-Ce2(WO4)3@CNF nanocomposite-modified glassy carbon electrode. Microchem J 165:106138. https:\/\/doi.org\/10.1016\/j.microc.2021.106138","journal-title":"Microchem J"},{"key":"6473_CR6","doi-asserted-by":"publisher","first-page":"86","DOI":"10.1016\/j.jelechem.2014.06.038","volume":"728","author":"L \u0160vorc","year":"2014","unstructured":"\u0160vorc L, Cinkov\u00e1 K, Sochr J et al (2014) Sensitive electrochemical determination of amlodipine in pharmaceutical tablets and human urine using a boron-doped diamond electrode. J Electroanal Chem 728:86\u201393. https:\/\/doi.org\/10.1016\/j.jelechem.2014.06.038","journal-title":"J Electroanal Chem"},{"key":"6473_CR7","doi-asserted-by":"publisher","first-page":"113259","DOI":"10.1016\/j.jelechem.2019.113259","volume":"847","author":"C Madhuri","year":"2019","unstructured":"Madhuri C, Manohara Reddy YV, Prabhakar Vattikuti SV et al (2019) Trace-level determination of amlodipine besylate by immobilization of palladium-silver bi-metallic nanoparticles on reduced graphene oxide as an electrochemical sensor. J Electroanal Chem 847:113259. https:\/\/doi.org\/10.1016\/j.jelechem.2019.113259","journal-title":"J Electroanal Chem"},{"key":"6473_CR8","doi-asserted-by":"publisher","first-page":"104827","DOI":"10.1016\/j.ultsonch.2019.104827","volume":"64","author":"BS Lou","year":"2020","unstructured":"Lou BS, Rajaji U, Chen SM, Chen TW (2020) A simple sonochemical assisted synthesis of NiMoO4\/chitosan nanocomposite for electrochemical sensing of amlodipine in pharmaceutical and serum samples. Ultrason Sonochem 64:104827. https:\/\/doi.org\/10.1016\/j.ultsonch.2019.104827","journal-title":"Ultrason Sonochem"},{"key":"6473_CR9","doi-asserted-by":"publisher","first-page":"027511","DOI":"10.1149\/1945-7111\/ab68cd","volume":"167","author":"M Doulache","year":"2020","unstructured":"Doulache M, Bakirhan NK, Saidat B, Ozkan SA (2020) Highly sensitive and selective electrochemical sensor based on polyglycine modified glassy carbon electrode for simultaneous determination of amlodipine and ramipril from biological samples. J Electrochem Soc 167:027511. https:\/\/doi.org\/10.1149\/1945-7111\/ab68cd","journal-title":"J Electrochem Soc"},{"key":"6473_CR10","doi-asserted-by":"publisher","first-page":"375","DOI":"10.4103\/0972-5229.123452","volume":"17","author":"V Upreti","year":"2013","unstructured":"Upreti V, Ratheesh VR, Dhull P, Handa A (2013) Shock due to amlodipine overdose. Indian J Crit Care Med 17:375\u2013377. https:\/\/doi.org\/10.4103\/0972-5229.123452","journal-title":"Indian J Crit Care Med"},{"key":"6473_CR11","doi-asserted-by":"publisher","first-page":"768","DOI":"10.1016\/j.snb.2016.07.165","volume":"239","author":"M Khairy","year":"2017","unstructured":"Khairy M, Khorshed AA, Rashwan FA et al (2017) Sensitive determination of amlodipine besylate using bare\/unmodified and DNA-modified screen-printed electrodes in tablets and biological fluids. Sens Actuators B Chem 239:768\u2013775. https:\/\/doi.org\/10.1016\/j.snb.2016.07.165","journal-title":"Sens Actuators B Chem"},{"key":"6473_CR12","doi-asserted-by":"publisher","first-page":"754","DOI":"10.1016\/j.talanta.2010.01.009","volume":"81","author":"X Kang","year":"2010","unstructured":"Kang X, Wang J, Wu H et al (2010) A graphene-based electrochemical sensor for sensitive detection of paracetamol. Talanta 81:754\u2013759. https:\/\/doi.org\/10.1016\/j.talanta.2010.01.009","journal-title":"Talanta"},{"key":"6473_CR13","doi-asserted-by":"publisher","first-page":"909","DOI":"10.1016\/j.snb.2013.07.088","volume":"188","author":"J Luo","year":"2013","unstructured":"Luo J, Fan C, Wang X et al (2013) A novel electrochemical sensor for paracetamol based on molecularly imprinted polymeric micelles. Sens Actuators B Chem 188:909\u2013916. https:\/\/doi.org\/10.1016\/j.snb.2013.07.088","journal-title":"Sens Actuators B Chem"},{"key":"6473_CR14","doi-asserted-by":"publisher","first-page":"17","DOI":"10.1038\/asiamat.2010.137","volume":"3","author":"PR Solanki","year":"2011","unstructured":"Solanki PR, Kaushik A, Agrawal VV, Malhotra BD (2011) Nanostructured metal oxide-based biosensors. NPG Asia Mater 3:17\u201324","journal-title":"NPG Asia Mater"},{"key":"6473_CR15","doi-asserted-by":"publisher","first-page":"641","DOI":"10.1016\/j.snb.2009.07.043","volume":"141","author":"D Sun","year":"2009","unstructured":"Sun D, Zhang Y, Wang F et al (2009) Electrochemical sensor for simultaneous detection of ascorbic acid, uric acid and xanthine based on the surface enhancement effect of mesoporous silica. Sens Actuators B Chem 141:641\u2013645. https:\/\/doi.org\/10.1016\/j.snb.2009.07.043","journal-title":"Sens Actuators B Chem"},{"key":"6473_CR16","doi-asserted-by":"publisher","first-page":"119","DOI":"10.1016\/j.bios.2016.03.074","volume":"82","author":"D Zhao","year":"2016","unstructured":"Zhao D, Yu G, Tian K, Xu C (2016) A highly sensitive and stable electrochemical sensor for simultaneous detection towards ascorbic acid, dopamine, and uric acid based on the hierarchical nanoporous PtTi alloy. Biosens Bioelectron 82:119\u2013126. https:\/\/doi.org\/10.1016\/j.bios.2016.03.074","journal-title":"Biosens Bioelectron"},{"key":"6473_CR17","doi-asserted-by":"publisher","first-page":"302","DOI":"10.1016\/j.snb.2014.07.077","volume":"204","author":"C Wang","year":"2014","unstructured":"Wang C, Du J, Wang H et al (2014) A facile electrochemical sensor based on reduced graphene oxide and au nanoplates modified glassy carbon electrode for simultaneous detection of ascorbic acid, dopamine and uric acid. Sens Actuators B Chem 204:302\u2013309. https:\/\/doi.org\/10.1016\/j.snb.2014.07.077","journal-title":"Sens Actuators B Chem"},{"key":"6473_CR18","doi-asserted-by":"publisher","unstructured":"Atta NF, Galal A, Ahmed YM, El-Ads EH (2019) Design strategy and preparation of a conductive layered electrochemical sensor for simultaneous determination of ascorbic acid, dobutamine, acetaminophen and amlodipine. Sens Actuators B Chem 297. https:\/\/doi.org\/10.1016\/j.snb.2019.126648","DOI":"10.1016\/j.snb.2019.126648"},{"key":"6473_CR19","doi-asserted-by":"publisher","first-page":"127076","DOI":"10.1016\/j.matchemphys.2022.127076","volume":"295","author":"G Veerapandi","year":"2023","unstructured":"Veerapandi G, Lavanya N, Sekar C (2023) Ca2CuO3 perovskite nanomaterial for electrochemical sensing of four different analytes in the xanthine derivatives family. Mater Chem Phys 295:127076. https:\/\/doi.org\/10.1016\/j.matchemphys.2022.127076","journal-title":"Mater Chem Phys"},{"key":"6473_CR20","doi-asserted-by":"publisher","first-page":"278","DOI":"10.1016\/j.msec.2016.04.033","volume":"65","author":"N Lavanya","year":"2016","unstructured":"Lavanya N, Sekar C, Murugan R, Ravi G (2016) An ultrasensitive electrochemical sensor for simultaneous determination of xanthine, hypoxanthine and uric acid based on Co doped CeO2 nanoparticles. Mater Sci Eng C 65:278\u2013286. https:\/\/doi.org\/10.1016\/j.msec.2016.04.033","journal-title":"Mater Sci Eng C"},{"key":"6473_CR21","doi-asserted-by":"publisher","first-page":"3402","DOI":"10.1103\/PhysRevB.56.3402","volume":"56","author":"H Rosner","year":"1997","unstructured":"Rosner H, Eschrig H, Hayn R et al (1997) Electronic structure and magnetic properties of the linear chain cuprates Sr2CuO3 and Ca2CuO3. Phys Rev B - Condens Matter Mater Phys 56:3402\u20133412. https:\/\/doi.org\/10.1103\/PhysRevB.56.3402","journal-title":"Phys Rev B - Condens Matter Mater Phys"},{"key":"6473_CR22","doi-asserted-by":"publisher","first-page":"54","DOI":"10.1016\/j.electacta.2018.01.185","volume":"266","author":"D Zhu","year":"2018","unstructured":"Zhu D, Ma H, Pang H et al (2018) Facile fabrication of a non-enzymatic nanocomposite of heteropolyacids and CeO2@Pt alloy nanoparticles doped reduced graphene oxide and its application towards the simultaneous determination of xanthine and uric acid. Electrochim Acta 266:54\u201365. https:\/\/doi.org\/10.1016\/j.electacta.2018.01.185","journal-title":"Electrochim Acta"},{"key":"6473_CR23","doi-asserted-by":"publisher","first-page":"443","DOI":"10.1016\/j.electacta.2013.12.127","volume":"121","author":"AM Pisoschi","year":"2014","unstructured":"Pisoschi AM, Pop A, Serban AI, Fafaneata C (2014) Electrochemical methods for ascorbic acid determination. Electrochim Acta 121:443\u2013460","journal-title":"Electrochim Acta"},{"key":"6473_CR24","doi-asserted-by":"publisher","unstructured":"El-Said WA, Nasr O, Soliman AIA et al (2021) Fabrication of polypyrrole\/Au nanoflowers modified gold electrode for highly sensitive sensing of paracetamol in pharmaceutical formulation. Appl Surf Sci Adv. https:\/\/doi.org\/10.1016\/j.apsadv.2021.100065. 4:","DOI":"10.1016\/j.apsadv.2021.100065"},{"key":"6473_CR25","doi-asserted-by":"publisher","first-page":"1017","DOI":"10.1002\/elan.201900580","volume":"32","author":"A Dehdashti","year":"2020","unstructured":"Dehdashti A, Babaei A (2020) Highly sensitive electrochemical sensor based on Pt doped NiO nanoparticles\/MWCNTs nanocomposite modified electrode for simultaneous sensing of piroxicam and amlodipine. Electroanalysis 32:1017\u20131024. https:\/\/doi.org\/10.1002\/elan.201900580","journal-title":"Electroanalysis"},{"key":"6473_CR26","doi-asserted-by":"publisher","first-page":"12265","DOI":"10.1039\/d2nj01822e","volume":"46","author":"NF Atta","year":"2022","unstructured":"Atta NF, Galal A, El-Gohary ARM (2022) Electrochemical sensing of dobutamine, paracetamol, amlodipine, and daclatasvir in serum based on thiourea SAMs over nano-gold particles-CNTs composite. New J Chem 46:12265\u201312277. https:\/\/doi.org\/10.1039\/d2nj01822e","journal-title":"New J Chem"},{"key":"6473_CR27","doi-asserted-by":"publisher","first-page":"1263","DOI":"10.1002\/elan.201900601","volume":"32","author":"D Eskik\u00f6y Bayraktepe","year":"2020","unstructured":"Eskik\u00f6y Bayraktepe D, Yazan Z (2020) Application of single-use electrode based on nano-clay and MWCNT for simultaneous determination of acetaminophen, ascorbic acid and acetylsalicylic acid in pharmaceutical dosage. Electroanalysis 32:1263\u20131272. https:\/\/doi.org\/10.1002\/elan.201900601","journal-title":"Electroanalysis"},{"key":"6473_CR28","doi-asserted-by":"publisher","unstructured":"Akbari Javar H, Mahmoudi-Moghaddam H, Garkani-Nejad Z, Dehghannoudeh G (2022) Grass-like Pt-doped NiCo2O4 modified electrode for electrochemical detection of amlodipine. Meas J Int Meas Confed 191. https:\/\/doi.org\/10.1016\/j.measurement.2022.110790","DOI":"10.1016\/j.measurement.2022.110790"},{"key":"6473_CR29","doi-asserted-by":"publisher","first-page":"096501","DOI":"10.1149\/1945-7111\/ac1e59","volume":"168","author":"P Deng","year":"2021","unstructured":"Deng P, Feng J, Xiao J et al (2021) Application of a simple and sensitive electrochemical sensor in simultaneous determination of paracetamol and ascorbic acid. J Electrochem Soc 168:096501. https:\/\/doi.org\/10.1149\/1945-7111\/ac1e59","journal-title":"J Electrochem Soc"}],"container-title":["Microchimica Acta"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00604-024-06473-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00604-024-06473-3\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00604-024-06473-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,7,8]],"date-time":"2024-07-08T17:17:08Z","timestamp":1720459028000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00604-024-06473-3"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,6,20]]},"references-count":29,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2024,7]]}},"alternative-id":["6473"],"URL":"https:\/\/doi.org\/10.1007\/s00604-024-06473-3","relation":{},"ISSN":["0026-3672","1436-5073"],"issn-type":[{"value":"0026-3672","type":"print"},{"value":"1436-5073","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,6,20]]},"assertion":[{"value":"19 February 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"30 May 2024","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"20 June 2024","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Urine samples for this research have been collected from the Government Hospital in Karaikudi, where doctors conduct clinical tests that meet\u00a0ethical norms and protect participants\u2019 rights and well-being. As a result, ethical approval may not always be necessary for the use of human urine samples.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"The authors declare no competing interests.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}],"article-number":"409"}}