{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,25]],"date-time":"2026-08-25T02:54:33Z","timestamp":1787626473972,"version":"build-2736575974"},"reference-count":35,"publisher":"Springer Science and Business Media LLC","issue":"5","license":[{"start":{"date-parts":[[2025,4,9]],"date-time":"2025-04-09T00:00:00Z","timestamp":1744156800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2025,4,9]],"date-time":"2025-04-09T00:00:00Z","timestamp":1744156800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["21806083"],"award-info":[{"award-number":["21806083"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Microchim Acta"],"published-print":{"date-parts":[[2025,5]]},"DOI":"10.1007\/s00604-025-07145-6","type":"journal-article","created":{"date-parts":[[2025,4,9]],"date-time":"2025-04-09T18:05:18Z","timestamp":1744221918000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Porous covalent architecture-involved luminescent smart hydrogel with target-responsive framework for signal-amplified inspection of aflatoxin B1"],"prefix":"10.1007","volume":"192","author":[{"given":"Tong","family":"Zhai","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu-Di","family":"Shen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miao","family":"Yu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing-Min","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuo","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,4,9]]},"reference":[{"issue":"3","key":"7145_CR1","doi-asserted-by":"publisher","first-page":"176","DOI":"10.3390\/toxins11030176","volume":"11","author":"AM Fouad","year":"2019","unstructured":"Fouad AM, Ruan D, El-Senousey HK, Chen W, Jiang S, Zheng C (2019) Harmful effects and control strategies of aflatoxin B1 produced by Aspergillus flavus and Aspergillus parasiticus strains on poultry: review. Toxins (Basel) 11(3):176. https:\/\/doi.org\/10.3390\/toxins11030176","journal-title":"Toxins (Basel)"},{"key":"7145_CR2","doi-asserted-by":"publisher","first-page":"343609","DOI":"10.1016\/j.aca.2025.343609","volume":"1338","author":"T Yu","year":"2025","unstructured":"Yu T, Suo Z, Zhu J, Xu Y, Ren W, Liu Y, Wang H, Wei M, He B, Zhao R (2025) Applying hollow octahedron PtNPs\/Pd\u2013Cu2O nanozyme and highly conductive AuPtNPs\/Ni\u2013Co NCs to colorimetric -electrochemical dual-mode aptasensor for AFB1 detection. Anal Chim Acta 1338:343609. https:\/\/doi.org\/10.1016\/j.aca.2025.343609","journal-title":"Anal Chim Acta"},{"key":"7145_CR3","doi-asserted-by":"publisher","first-page":"138909","DOI":"10.1016\/j.foodchem.2024.138909","volume":"447","author":"M Frangiamone","year":"2024","unstructured":"Frangiamone M, L\u00e1zaro \u00c1, Cimbalo A, Font G, Manyes L (2024) In vitro and in vivo assessment of AFB1 and OTA toxic effects and the beneficial role of bioactive compounds: a systematic review. Food Chem 447:138909. https:\/\/doi.org\/10.1016\/j.foodchem.2024.138909","journal-title":"Food Chem"},{"key":"7145_CR4","doi-asserted-by":"publisher","first-page":"261","DOI":"10.1016\/j.chemosphere.2019.05.273","volume":"233","author":"X Chen","year":"2019","unstructured":"Chen X, Li C, Chen Y, Ni C, Chen X, Zhang L, Xu X, Chen M, Ma X, Zhan H, Xu A, Ge R, Guo X (2019) Aflatoxin B1 impairs Leydig cells through inhibiting AMPK\/mTOR-mediated autophagy flux pathway. Chemosphere 233:261\u2013272. https:\/\/doi.org\/10.1016\/j.chemosphere.2019.05.273","journal-title":"Chemosphere"},{"key":"7145_CR5","doi-asserted-by":"publisher","first-page":"101797","DOI":"10.1016\/j.fochx.2024.101797","volume":"24","author":"D Wei","year":"2024","unstructured":"Wei D, Li J, Zheng S, Guo M, Xu J, Deng Q, Wang X (2024) Effective extraction and detection of aflatoxins in cereals using nitrogen-rich benzodiimidazole linkage magnetic covalent organic framework based solid phase extraction and HPLC-MS\/MS analysis. Food Chem X 24:101797. https:\/\/doi.org\/10.1016\/j.fochx.2024.101797","journal-title":"Food Chem X"},{"key":"7145_CR6","doi-asserted-by":"publisher","first-page":"140231","DOI":"10.1016\/j.foodchem.2024.140231","volume":"458","author":"L Guo","year":"2024","unstructured":"Guo L, Zhang J, Bao Y, Zhang Y, Zhang D, Ma X, Zhang J (2024) Label-free and highly sensitive detection of aflatoxin B1 by Ag IANPs via surface-enhanced Raman spectroscopy. Food Chem 458:140231. https:\/\/doi.org\/10.1016\/j.foodchem.2024.140231","journal-title":"Food Chem"},{"key":"7145_CR7","doi-asserted-by":"publisher","first-page":"110317","DOI":"10.1016\/j.foodcont.2024.110317","volume":"160","author":"J Fu","year":"2024","unstructured":"Fu J, Gu M, Tang X, Zhang Q, Li P (2024) Early evaluation of aflatoxin occurrence risk using an ultra-sensitive immunoassay for pre-aflatoxin protein biomarker detection. Food Control 160:110317. https:\/\/doi.org\/10.1016\/j.foodcont.2024.110317","journal-title":"Food Control"},{"key":"7145_CR8","doi-asserted-by":"publisher","first-page":"123154","DOI":"10.1016\/j.jhazmat.2020.123154","volume":"399","author":"L Wu","year":"2020","unstructured":"Wu L, Zhou M, Wang Y, Liu J (2020) Nanozyme and aptamer- based immunosorbent assay for aflatoxin B1. J Hazard Mater 399:123154. https:\/\/doi.org\/10.1016\/j.jhazmat.2020.123154","journal-title":"J Hazard Mater"},{"key":"7145_CR9","doi-asserted-by":"publisher","first-page":"104846","DOI":"10.1016\/j.tifs.2024.104846","volume":"156","author":"X Wang","year":"2025","unstructured":"Wang X, He L, Rong X, Liu L, Yin Y, Zhao X, Weng Y (2025) DNA aptamer-crosslinked hydrogel sensor: design, mechanism and application for food safety analysis. Trends Food Sci Technol 156:104846. https:\/\/doi.org\/10.1016\/j.tifs.2024.104846","journal-title":"Trends Food Sci Technol"},{"key":"7145_CR10","doi-asserted-by":"publisher","first-page":"102060","DOI":"10.1016\/j.cis.2019.102060","volume":"275","author":"S Khajouei","year":"2020","unstructured":"Khajouei S, Ravan H, Ebrahimi A (2020) DNA hydrogel-empowered biosensing. Adv Colloid Interface Sci 275:102060. https:\/\/doi.org\/10.1016\/j.cis.2019.102060","journal-title":"Adv Colloid Interface Sci"},{"issue":"29","key":"7145_CR11","doi-asserted-by":"publisher","first-page":"2101224","DOI":"10.1002\/smll.202101224","volume":"17","author":"X Fu","year":"2021","unstructured":"Fu X, Chen T, Song Y, Feng C, Chen H, Zhang Q, Chen G, Zhu X (2021) mRNA delivery by a pH-responsive DNA nano-hydrogel. Small 17(29):2101224. https:\/\/doi.org\/10.1002\/smll.202101224","journal-title":"Small"},{"issue":"1","key":"7145_CR12","doi-asserted-by":"publisher","first-page":"381","DOI":"10.1038\/s41467-017-00298-w","volume":"8","author":"L Zhang","year":"2017","unstructured":"Zhang L, Jean SR, Ahmed S, Aldridge PM, Li X, Fan F, Sargent EH, Kelley SO (2017) Multifunctional quantum dot DNA hydrogels. Nat Commun 8(1):381. https:\/\/doi.org\/10.1038\/s41467-017-00298-w","journal-title":"Nat Commun"},{"key":"7145_CR13","doi-asserted-by":"publisher","first-page":"339795","DOI":"10.1016\/j.aca.2022.339795","volume":"1207","author":"S Yao","year":"2022","unstructured":"Yao S, Xiang L, Wang L, Gong H, Chen F, Cai C (2022) pH-responsive DNA hydrogels with ratiometric fluorescence for accurate detection of miRNA-21. Anal Chim Acta 1207:339795. https:\/\/doi.org\/10.1016\/j.aca.2022.339795","journal-title":"Anal Chim Acta"},{"key":"7145_CR14","doi-asserted-by":"publisher","first-page":"96","DOI":"10.1016\/j.aca.2020.08.004","volume":"1134","author":"P Wu","year":"2020","unstructured":"Wu P, Li S, Ye X, Ning B, Bai J, Peng Y, Li L, Han T, Zhou H, Gao Z, Ding P (2020) Cu\/Au\/Pt trimetallic nanoparticles coated with DNA hydrogel as target-responsive and signal-amplification material for sensitive detection of microcystin-LR. Anal Chim Acta 1134:96\u2013105. https:\/\/doi.org\/10.1016\/j.aca.2020.08.004","journal-title":"Anal Chim Acta"},{"issue":"11","key":"7145_CR15","doi-asserted-by":"publisher","first-page":"395","DOI":"10.1007\/s00604-021-05000-y","volume":"188","author":"L Hao","year":"2021","unstructured":"Hao L, Liu X, Xu S, An F, Gu H, Xu F (2021) A novel aptasensor based on DNA hydrogel for sensitive visual detection of ochratoxin A. Microchim Acta 188(11):395. https:\/\/doi.org\/10.1007\/s00604-021-05000-y","journal-title":"Microchim Acta"},{"key":"7145_CR16","doi-asserted-by":"publisher","first-page":"133402","DOI":"10.1016\/j.snb.2023.133402","volume":"380","author":"Y Bian","year":"2023","unstructured":"Bian Y, Zhou Z, Li G, Liu S, Li S, Gao Z, Kang W (2023) Bimetallic nanozymes laden DNA hydrogel for ultrasensitive optical detection of ractopamine. Sensors Actuators B Chem 380:133402. https:\/\/doi.org\/10.1016\/j.snb.2023.133402","journal-title":"Sensors Actuators B Chem"},{"key":"7145_CR17","doi-asserted-by":"publisher","unstructured":"Marvi PK, Das P, Jafari A, Hassan S, Savoji H, Srinivasan S, Rajabzadeh AR (2025) Multifunctional carbon dots in situ confined hydrogel for optical communication, drug delivery, pH sensing, nanozymatic activity, and UV shielding applications. Adv Healthc Mater 2403876.https:\/\/doi.org\/10.1002\/adhm.202403876","DOI":"10.1002\/adhm.202403876"},{"issue":"3","key":"7145_CR18","doi-asserted-by":"publisher","first-page":"1806538","DOI":"10.1002\/adma.201806538","volume":"32","author":"F Li","year":"2020","unstructured":"Li F, Lyu D, Liu S, Guo W (2020) DNA hydrogels and microgels for biosensing and biomedical applications. Adv Mater 32(3):1806538. https:\/\/doi.org\/10.1002\/adma.201806538","journal-title":"Adv Mater"},{"issue":"4","key":"7145_CR19","doi-asserted-by":"publisher","first-page":"733","DOI":"10.1021\/acs.accounts.6b00581","volume":"50","author":"D Wang","year":"2017","unstructured":"Wang D, Hu Y, Liu P, Luo D (2017) Bioresponsive DNA hydrogels: beyond the conventional stimuli responsiveness. Acc Chem Res 50(4):733\u2013739. https:\/\/doi.org\/10.1021\/acs.accounts.6b00581","journal-title":"Acc Chem Res"},{"key":"7145_CR20","doi-asserted-by":"publisher","first-page":"135457","DOI":"10.1016\/j.snb.2024.135457","volume":"407","author":"Z Su","year":"2024","unstructured":"Su Z, Kong Y, Li T, Zhao Y, Zhang X, Wu D, Wu Y, Li G (2024) An aptamer-triggered hybridization chain reaction strategy for ultra-sensitive biological nanopore detection of aflatoxin B1. Sensors Actuators B Chem 407:135457. https:\/\/doi.org\/10.1016\/j.snb.2024.135457","journal-title":"Sensors Actuators B Chem"},{"issue":"10","key":"7145_CR21","doi-asserted-by":"publisher","first-page":"594","DOI":"10.1007\/s00604-024-06665-x","volume":"191","author":"L Guo","year":"2024","unstructured":"Guo L, Zhou S, Xue J, Liu Z, Xu S, He Z, Yang H (2024) Signal-enhanced electrochemical sensor employing MWCNTs\/CMK-3\/AuNPs and Au@Pd core\u2013shell structure for sensitive determination\u00a0of AFB1 in complex matrix. Microchim Acta 191(10):594. https:\/\/doi.org\/10.1007\/s00604-024-06665-x","journal-title":"Microchim Acta"},{"key":"7145_CR22","doi-asserted-by":"publisher","first-page":"140234","DOI":"10.1016\/j.foodchem.2024.140234","volume":"459","author":"S Wang","year":"2024","unstructured":"Wang S, Hu X, Wu W, Wang D, Li P, Zhang Z (2024) Dual-template magnetic molecularly imprinted polymers for selective extraction and sensitive detection of aflatoxin B1 and benzo(\u03b1)pyrene in environmental water and edible oil. Food Chem 459:140234. https:\/\/doi.org\/10.1016\/j.foodchem.2024.140234","journal-title":"Food Chem"},{"key":"7145_CR23","doi-asserted-by":"publisher","first-page":"34","DOI":"10.1016\/j.talanta.2017.08.006","volume":"176","author":"M Zhao","year":"2018","unstructured":"Zhao M, Wang P, Guo Y, Wang L, Luo F, Qiu B, Guo L, Su X, Lin Z, Chen G (2018) Detection of aflatoxin B1 in food samples based on target-responsive aptamer-cross-linked hydrogel using a handheld pH meter as readout. Talanta 176:34\u201339. https:\/\/doi.org\/10.1016\/j.talanta.2017.08.006","journal-title":"Talanta"},{"key":"7145_CR24","doi-asserted-by":"publisher","first-page":"135424","DOI":"10.1016\/j.jhazmat.2024.135424","volume":"478","author":"F Li","year":"2024","unstructured":"Li F, Chen C, Jin H, Ding T, Feng J, Qiu W, Wang Q (2024) Selective lead capture using amide-containing COFs: a novel strategy for efficient soil remediation. J Hazard Mater 478:135424. https:\/\/doi.org\/10.1016\/j.jhazmat.2024.135424","journal-title":"J Hazard Mater"},{"key":"7145_CR25","doi-asserted-by":"publisher","first-page":"128705","DOI":"10.1016\/j.jhazmat.2022.128705","volume":"432","author":"W Li","year":"2022","unstructured":"Li W, Jiang H-X, Cui M-F, Wang R, Tang A-N, Kong D-M (2022) SiO2 templates-derived hierarchical porous COFs sample pretreatment tool for non-targeted analysis of chemicals in foods. J Hazard Mater 432:128705. https:\/\/doi.org\/10.1016\/j.jhazmat.2022.128705","journal-title":"J Hazard Mater"},{"key":"7145_CR26","doi-asserted-by":"publisher","first-page":"136622","DOI":"10.1016\/j.jhazmat.2024.136622","volume":"483","author":"L Liang","year":"2025","unstructured":"Liang L, Cai S-q, Leng Y-l, Huang C, Liu Y-q, Wang Y, Luo L, Han M, Li X-h, Cai X-h (2025) J Hazard Mater 483:136622. https:\/\/doi.org\/10.1016\/j.jhazmat.2024.136622","journal-title":"J Hazard Mater"},{"key":"7145_CR27","doi-asserted-by":"publisher","first-page":"100376","DOI":"10.1016\/j.mtadv.2023.100376","volume":"18","author":"H-L Yang","year":"2023","unstructured":"Yang H-L, Bai L-F, Geng Z-R, Chen H, Xu L-T, Xie Y-C, Wang D-J, Gu H-W, Wang X-M (2023) Carbon quantum dots: preparation, optical properties, and biomedical applications. Mater Today Adv 18:100376. https:\/\/doi.org\/10.1016\/j.mtadv.2023.100376","journal-title":"Mater Today Adv"},{"key":"7145_CR28","doi-asserted-by":"publisher","first-page":"265","DOI":"10.1016\/j.carbon.2020.05.060","volume":"166","author":"Y Fang","year":"2020","unstructured":"Fang Y, Zhou L, Zhao J, Zhang Y, Yang M, Yi C (2020) Facile synthesis of pH-responsive gadolinium(III)-doped carbon nanodots with red fluorescence and magnetic resonance properties for dual-readout logic gate operations. Carbon 166:265\u2013272. https:\/\/doi.org\/10.1016\/j.carbon.2020.05.060","journal-title":"Carbon"},{"issue":"12","key":"7145_CR29","doi-asserted-by":"publisher","first-page":"6982","DOI":"10.1021\/acsami.5b01120","volume":"7","author":"R Liu","year":"2015","unstructured":"Liu R, Huang Y, Ma Y, Jia S, Gao M, Li J, Zhang H, Xu D, Wu M, Chen Y, Zhu Z, Yang C (2015) Design and synthesis of target-responsive aptamer-cross-linked hydrogel for visual quantitative detection of ochratoxin A. ACS Appl Mater Interfaces 7(12):6982\u20136990. https:\/\/doi.org\/10.1021\/acsami.5b01120","journal-title":"ACS Appl Mater Interfaces"},{"issue":"10","key":"7145_CR30","doi-asserted-by":"publisher","first-page":"3748","DOI":"10.1021\/ja3114714","volume":"135","author":"L Yan","year":"2013","unstructured":"Yan L, Zhu Z, Zou Y, Huang Y, Liu D, Jia S, Xu D, Wu M, Zhou Y, Zhou S, Yang CJ (2013) Target-responsive \u201csweet\u201d hydrogel with glucometer readout for portable and quantitative detection of non-glucose targets. J Am Chem Soc 135(10):3748\u20133751. https:\/\/doi.org\/10.1021\/ja3114714","journal-title":"J Am Chem Soc"},{"issue":"23","key":"7145_CR31","doi-asserted-by":"publisher","first-page":"15907","DOI":"10.1007\/s10853-018-2764-8","volume":"53","author":"K Zheng","year":"2018","unstructured":"Zheng K, Guan L, Ma H, Zhao S, Zhao J, Wang Z, Dong G, Wei Z, Li X (2018) Excitation-dependent carbon dots powders based on dehydration condensation by microwave\u2013hydrothermal method. J Mater Sci 53(23):15907\u201315914. https:\/\/doi.org\/10.1007\/s10853-018-2764-8","journal-title":"J Mater Sci"},{"key":"7145_CR32","doi-asserted-by":"publisher","first-page":"128113","DOI":"10.1016\/j.matchemphys.2023.128113","volume":"307","author":"TD Thangadurai","year":"2023","unstructured":"Thangadurai TD, Manjubaashini N, Sowndarya A, Subitha A, Kausalya G, Shanmugaraju S, Ahmad I, Thomas S, Kalarikkal N (2023) Multipurpose biological applications of excitation-dependent fluorescent carbon nano dots emanated from biomass waste. Mater Chem Phys 307:128113. https:\/\/doi.org\/10.1016\/j.matchemphys.2023.128113","journal-title":"Mater Chem Phys"},{"key":"7145_CR33","doi-asserted-by":"publisher","first-page":"78","DOI":"10.1016\/j.carbon.2017.11.069","volume":"128","author":"W Yang","year":"2018","unstructured":"Yang W, Zhang H, Lai J, Peng X, Hu Y, Gu W, Ye L (2018) Carbon dots with red-shifted photoluminescence by fluorine doping for optical bio-imaging. Carbon 128:78\u201385. https:\/\/doi.org\/10.1016\/j.carbon.2017.11.069","journal-title":"Carbon"},{"key":"7145_CR34","doi-asserted-by":"publisher","first-page":"114026","DOI":"10.1016\/j.matchar.2024.114026","volume":"213","author":"H Chen","year":"2024","unstructured":"Chen H, Chen Y, Liang Z-B, Shen A, Chen L, Guo J, Wang C-F, Chen S (2024) Preparation and characterization of chiral carbon dots with red emission. Mater Charact 213:114026. https:\/\/doi.org\/10.1016\/j.matchar.2024.114026","journal-title":"Mater Charact"},{"issue":"45","key":"7145_CR35","doi-asserted-by":"publisher","first-page":"18271","DOI":"10.1021\/jacs.9b09189","volume":"141","author":"W Ma","year":"2019","unstructured":"Ma W, Zheng Q, He Y, Li G, Guo W, Lin Z, Zhang L (2019) Size-controllable synthesis of uniform spherical covalent organic frameworks at room temperature for highly efficient and selective enrichment of hydrophobic peptides. J Am Chem Soc 141(45):18271\u201318277. https:\/\/doi.org\/10.1021\/jacs.9b09189","journal-title":"J Am Chem Soc"}],"container-title":["Microchimica Acta"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00604-025-07145-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00604-025-07145-6\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00604-025-07145-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,5,10]],"date-time":"2025-05-10T12:38:19Z","timestamp":1746880699000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00604-025-07145-6"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,4,9]]},"references-count":35,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2025,5]]}},"alternative-id":["7145"],"URL":"https:\/\/doi.org\/10.1007\/s00604-025-07145-6","relation":{},"ISSN":["0026-3672","1436-5073"],"issn-type":[{"value":"0026-3672","type":"print"},{"value":"1436-5073","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,4,9]]},"assertion":[{"value":"18 February 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"29 March 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"9 April 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Since the research does not involve human participants, animals, or any bioethical concerns, no ethical approval was required for this study. The experimental methods were carried out in accordance with the relevant safety and research guidelines for materials science and analytical chemistry. If applicable, the study adhered to institutional and national regulations concerning the handling and disposal of chemicals and materials used in the experiments.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"The authors declare no competing interests.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}],"article-number":"289"}}