{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,2]],"date-time":"2026-08-02T21:35:42Z","timestamp":1785706542649,"version":"3.56.0"},"reference-count":58,"publisher":"Springer Science and Business Media LLC","issue":"7","license":[{"start":{"date-parts":[[2025,6,12]],"date-time":"2025-06-12T00:00:00Z","timestamp":1749686400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2025,6,12]],"date-time":"2025-06-12T00:00:00Z","timestamp":1749686400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"DOI":"10.13039\/501100006769","name":"Russian Science Foundation","doi-asserted-by":"publisher","award":["23-13-00380"],"award-info":[{"award-number":["23-13-00380"]}],"id":[{"id":"10.13039\/501100006769","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100006769","name":"Russian Science Foundation","doi-asserted-by":"publisher","award":["23-13-00380"],"award-info":[{"award-number":["23-13-00380"]}],"id":[{"id":"10.13039\/501100006769","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100006769","name":"Russian Science Foundation","doi-asserted-by":"publisher","award":["23-13-00380"],"award-info":[{"award-number":["23-13-00380"]}],"id":[{"id":"10.13039\/501100006769","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100006769","name":"Russian Science Foundation","doi-asserted-by":"publisher","award":["23-13-00380"],"award-info":[{"award-number":["23-13-00380"]}],"id":[{"id":"10.13039\/501100006769","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100006769","name":"Russian Science Foundation","doi-asserted-by":"publisher","award":["23-13-00380"],"award-info":[{"award-number":["23-13-00380"]}],"id":[{"id":"10.13039\/501100006769","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100006769","name":"Russian Science Foundation","doi-asserted-by":"publisher","award":["23-13-00380"],"award-info":[{"award-number":["23-13-00380"]}],"id":[{"id":"10.13039\/501100006769","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100006769","name":"Russian Science Foundation","doi-asserted-by":"publisher","award":["23-13-00380"],"award-info":[{"award-number":["23-13-00380"]}],"id":[{"id":"10.13039\/501100006769","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Microchim Acta"],"published-print":{"date-parts":[[2025,7]]},"DOI":"10.1007\/s00604-025-07283-x","type":"journal-article","created":{"date-parts":[[2025,6,11]],"date-time":"2025-06-11T18:47:26Z","timestamp":1749667646000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Doxorubicin detection in plasma and blood using a luminescence turn-off nanosensor based on alloyed CdZnSeS\/ZnS quantum dots"],"prefix":"10.1007","volume":"192","author":[{"given":"Svetlana A.","family":"Mescheryakova","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daria G.","family":"Koganova","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daria V.","family":"Tsyupka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Danila A.","family":"Kornilov","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pavel S.","family":"Pidenko","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniil D.","family":"Drozd","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olga A.","family":"Goryacheva","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Irina Yu.","family":"Goryacheva","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,6,12]]},"reference":[{"key":"7283_CR1","doi-asserted-by":"crossref","unstructured":"Beretta GL, Zunino F (2008) Molecular Mechanisms of anthracycline activity. In: Krohn K (ed) Anthracycline Chemistry and Biology II. Topics in Current Chemistry. Springer, Berlin, Heidelberg, pp 1\u201319","DOI":"10.1007\/128_2007_3"},{"key":"7283_CR2","doi-asserted-by":"publisher","first-page":"119527","DOI":"10.1016\/j.lfs.2021.119527","volume":"278","author":"S Sritharan","year":"2021","unstructured":"Sritharan S, Sivalingam N (2021) A comprehensive review on time-tested anticancer drug doxorubicin. Life Sci 278:119527. https:\/\/doi.org\/10.1016\/j.lfs.2021.119527","journal-title":"Life Sci"},{"key":"7283_CR3","doi-asserted-by":"publisher","first-page":"431","DOI":"10.2165\/00003088-200241060-00004","volume":"41","author":"R Danesi","year":"2002","unstructured":"Danesi R, Fogli S, Gennari A et al (2002) Pharmacokinetic-pharmacodynamic relationships of the anthracycline anticancer drugs. Clin Pharmacokinet 41:431\u2013444. https:\/\/doi.org\/10.2165\/00003088-200241060-00004","journal-title":"Clin Pharmacokinet"},{"key":"7283_CR4","doi-asserted-by":"publisher","unstructured":"Heibein AD, Guo B, Sprowl JA, et al (2012) Role of aldo-keto reductases and other doxorubicin pharmacokinetic genes in doxorubicin resistance, DNA binding, and subcellular localization. BMC Cancer 12. https:\/\/doi.org\/10.1186\/1471-2407-12-381","DOI":"10.1186\/1471-2407-12-381"},{"key":"7283_CR5","doi-asserted-by":"publisher","first-page":"3469","DOI":"10.2147\/DDDT.S251144","volume":"14","author":"Y Harahap","year":"2020","unstructured":"Harahap Y, Ardiningsih P, Winarti AC, Purwanto DJ (2020) Analysis of the doxorubicin and doxorubicinol in the plasma of breast cancer patients for monitoring the toxicity of doxorubicin. Drug Des Devel Ther 14:3469\u20133475. https:\/\/doi.org\/10.2147\/DDDT.S251144","journal-title":"Drug Des Devel Ther"},{"key":"7283_CR6","doi-asserted-by":"publisher","first-page":"112","DOI":"10.3390\/ph15020112","volume":"15","author":"T Sikora","year":"2022","unstructured":"Sikora T, Morawska K, Lisowski W et al (2022) Application of optical methods for determination of concentration of doxorubicin in blood and plasma. Pharmaceuticals 15:112. https:\/\/doi.org\/10.3390\/ph15020112","journal-title":"Pharmaceuticals"},{"key":"7283_CR7","doi-asserted-by":"publisher","first-page":"118","DOI":"10.1016\/j.jpba.2015.08.037","volume":"117","author":"X Yang","year":"2016","unstructured":"Yang X, Gao H, Qian F et al (2016) Internal standard method for the measurement of doxorubicin and daunorubicin by capillary electrophoresis with in-column double optical-fiber LED-induced fluorescence detection. J Pharm Biomed Anal 117:118\u2013124. https:\/\/doi.org\/10.1016\/j.jpba.2015.08.037","journal-title":"J Pharm Biomed Anal"},{"key":"7283_CR8","doi-asserted-by":"publisher","first-page":"135180","DOI":"10.1016\/j.electacta.2019.135180","volume":"330","author":"\u0160 Skalov\u00e1","year":"2020","unstructured":"Skalov\u00e1 \u0160, Langmaier J, Barek J et al (2020) Doxorubicin determination using two novel voltammetric approaches: a comparative study. Electrochim Acta 330:135180. https:\/\/doi.org\/10.1016\/j.electacta.2019.135180","journal-title":"Electrochim Acta"},{"key":"7283_CR9","doi-asserted-by":"publisher","first-page":"1223","DOI":"10.3390\/nano13071223","volume":"13","author":"F Kong","year":"2023","unstructured":"Kong F, Luo J, Jing L et al (2023) Reduced graphene oxide and gold nanoparticles-modified electrochemical aptasensor for highly sensitive detection of doxorubicin. Nanomaterials 13:1223. https:\/\/doi.org\/10.3390\/nano13071223","journal-title":"Nanomaterials"},{"key":"7283_CR10","doi-asserted-by":"publisher","first-page":"110527","DOI":"10.1016\/j.inoche.2023.110527","volume":"150","author":"Th Abhishek Singh","year":"2023","unstructured":"Abhishek Singh Th, Sharma V, Thakur N et al (2023) Selective and sensitive electrochemical detection of doxorubicin via a novel magnesium oxide\/carbon dot nanocomposite based sensor. Inorg Chem Commun 150:110527. https:\/\/doi.org\/10.1016\/j.inoche.2023.110527","journal-title":"Inorg Chem Commun"},{"key":"7283_CR11","doi-asserted-by":"publisher","first-page":"271","DOI":"10.1016\/S0378-4347(98)00475-7","volume":"721","author":"L \u00c1lvarez-Cedr\u00f3n","year":"1999","unstructured":"\u00c1lvarez-Cedr\u00f3n L, Sayalero ML, Lanao JM (1999) High-performance liquid chromatographic validated assay of doxorubicin in rat plasma and tissues. J Chromatogr B Biomed Sci Appl 721:271\u2013278. https:\/\/doi.org\/10.1016\/S0378-4347(98)00475-7","journal-title":"J Chromatogr B Biomed Sci Appl"},{"key":"7283_CR12","doi-asserted-by":"publisher","first-page":"376","DOI":"10.1016\/j.jpba.2018.06.031","volume":"158","author":"O Maliszewska","year":"2018","unstructured":"Maliszewska O, Plenis A, Ol\u0119dzka I et al (2018) Optimization of LC method for the quantification of doxorubicin in plasma and urine samples in view of pharmacokinetic, biomedical and drug monitoring therapy studies. J Pharm Biomed Anal 158:376\u2013385. https:\/\/doi.org\/10.1016\/j.jpba.2018.06.031","journal-title":"J Pharm Biomed Anal"},{"key":"7283_CR13","doi-asserted-by":"publisher","first-page":"1254","DOI":"10.3390\/molecules25051254","volume":"25","author":"WG Choi","year":"2020","unstructured":"Choi WG, Kim DK, Shin Y et al (2020) Liquid chromatography\u2013tandem mass spectrometry for the simultaneous determination of doxorubicin and its metabolites doxorubicinol, doxorubicinone, doxorubicinolone, and 7-deoxydoxorubicinone in mouse plasma. Molecules 25:1254. https:\/\/doi.org\/10.3390\/molecules25051254","journal-title":"Molecules"},{"key":"7283_CR14","doi-asserted-by":"publisher","first-page":"186","DOI":"10.1556\/1326.2023.01129","volume":"36","author":"K Zhang","year":"2024","unstructured":"Zhang K, Zhang D, Ge Z, Qiu F (2024) Development and validation of an LC-MS\/MS method for the quantification of free and total doxorubicin in human plasma and its clinical application for a novel doxorubicin hydrochloride liposome injection in Chinese patients with breast cancer. Acta Chromatogr 36:186\u2013195. https:\/\/doi.org\/10.1556\/1326.2023.01129","journal-title":"Acta Chromatogr"},{"key":"7283_CR15","doi-asserted-by":"publisher","first-page":"958","DOI":"10.1002\/jps.2600660714","volume":"66","author":"RJ Sturgeon","year":"1977","unstructured":"Sturgeon RJ, Schulman SG (1977) Electronic absorption spectra and protolytic equilibria of doxorubicin: direct spectrophotometric determination of microconstants. J Pharm Sci 66:958\u2013961. https:\/\/doi.org\/10.1002\/jps.2600660714","journal-title":"J Pharm Sci"},{"key":"7283_CR16","doi-asserted-by":"publisher","first-page":"766","DOI":"10.1002\/jps.2600730615","volume":"73","author":"M Menozzi","year":"1984","unstructured":"Menozzi M, Valentini L, Vannini E, Arcamone F (1984) Self-association of doxorubicin and related compounds in aqueous solution. J Pharm Sci 73:766\u2013770. https:\/\/doi.org\/10.1002\/jps.2600730615","journal-title":"J Pharm Sci"},{"key":"7283_CR17","doi-asserted-by":"publisher","first-page":"354","DOI":"10.1016\/j.ijbiomac.2016.03.060","volume":"88","author":"D Agudelo","year":"2016","unstructured":"Agudelo D, B\u00e9rub\u00e9 G, Tajmir-Riahi HA (2016) An overview on the delivery of antitumor drug doxorubicin by carrier proteins. Int J Biol Macromol 88:354\u2013360","journal-title":"Int J Biol Macromol"},{"key":"7283_CR18","doi-asserted-by":"publisher","first-page":"8195","DOI":"10.1002\/chem.201800644","volume":"24","author":"E Tasca","year":"2018","unstructured":"Tasca E, D\u2019Abramo M, Galantini L et al (2018) A stereochemically driven supramolecular polymerisation. Chem Eur J 24:8195\u20138204. https:\/\/doi.org\/10.1002\/chem.201800644","journal-title":"Chem Eur J"},{"key":"7283_CR19","doi-asserted-by":"publisher","first-page":"517","DOI":"10.1016\/j.colsurfa.2019.06.005","volume":"577","author":"E Tasca","year":"2019","unstructured":"Tasca E, Alba J, Galantini L et al (2019) The self-association equilibria of doxorubicin at high concentration and ionic strength characterized by fluorescence spectroscopy and molecular dynamics simulations. Colloids Surf A Physicochem Eng Asp 577:517\u2013522. https:\/\/doi.org\/10.1016\/j.colsurfa.2019.06.005","journal-title":"Colloids Surf A Physicochem Eng Asp"},{"key":"7283_CR20","doi-asserted-by":"publisher","first-page":"112323","DOI":"10.1016\/j.optmat.2022.112323","volume":"128","author":"W Zhang","year":"2022","unstructured":"Zhang W, Ma R, Gu S et al (2022) Nitrogen and phosphorus co-doped carbon dots as an effective fluorescence probe for the detection of doxorubicin and cell imaging. Opt Mater (Amst) 128:112323. https:\/\/doi.org\/10.1016\/j.optmat.2022.112323","journal-title":"Opt Mater (Amst)"},{"key":"7283_CR21","doi-asserted-by":"publisher","first-page":"110743","DOI":"10.1016\/j.optmat.2020.110743","volume":"112","author":"M Yang","year":"2021","unstructured":"Yang M, Yan Y, Liu E et al (2021) Polyethyleneimine-functionalized carbon dots as a fluorescent probe for doxorubicin hydrochloride by an inner filter effect. Opt Mater (Amst) 112:110743. https:\/\/doi.org\/10.1016\/j.optmat.2020.110743","journal-title":"Opt Mater (Amst)"},{"key":"7283_CR22","doi-asserted-by":"publisher","first-page":"41383","DOI":"10.1021\/acsomega.3c05093","volume":"8","author":"F Du","year":"2023","unstructured":"Du F, Gao Y, Zhang X, Wang LL (2023) Bismuth, nitrogen-codoped carbon dots as a dual-read optical sensing platform for highly sensitive, ultrarapid, ratiometric detection of doxorubicin. ACS Omega 8:41383\u201341390. https:\/\/doi.org\/10.1021\/acsomega.3c05093","journal-title":"ACS Omega"},{"key":"7283_CR23","doi-asserted-by":"publisher","first-page":"868","DOI":"10.1002\/bio.4230","volume":"37","author":"F Li","year":"2022","unstructured":"Li F, Fan P, Chen X et al (2022) A ratiometric fluorescence strategy based on copper nanoclusters\/carbon dots for sensitive detection of doxorubicin. Luminescence 37:868\u2013875. https:\/\/doi.org\/10.1002\/bio.4230","journal-title":"Luminescence"},{"key":"7283_CR24","doi-asserted-by":"publisher","DOI":"10.1007\/s10895-024-03779-6","author":"MS Polat","year":"2024","unstructured":"Polat MS, Nadaroglu H (2024) Utilizing copper nanoclusters as a fluorescent probe for quantitative monitoring of doxorubicin anticancer drug. J Fluoresc. https:\/\/doi.org\/10.1007\/s10895-024-03779-6","journal-title":"J Fluoresc"},{"key":"7283_CR25","doi-asserted-by":"publisher","first-page":"318","DOI":"10.1134\/S106193482470179X","volume":"80","author":"YuA Podkolodnaya","year":"2025","unstructured":"Podkolodnaya YuA, Kalishina KR, Zobnina EA et al (2025) Luminescent gold nanoclusters stabilized by protein as nanosensors for the detection of doxorubicin. J Anal Chem 80:318\u2013326. https:\/\/doi.org\/10.1134\/S106193482470179X","journal-title":"J Anal Chem"},{"key":"7283_CR26","doi-asserted-by":"publisher","first-page":"869","DOI":"10.1016\/j.ultrasmedbio.2024.02.012","volume":"50","author":"Z Kayani","year":"2024","unstructured":"Kayani Z, Heli H, DehdariVais R et al (2024) Synchronized chemotherapy\/photothermal therapy\/sonodynamic therapy of human triple-negative and estrogen receptor-positive breast cancer cells using a doxorubicin\u2013gold nanoclusters\u2013albumin nanobioconjugate. Ultrasound Med Biol 50:869\u2013881. https:\/\/doi.org\/10.1016\/j.ultrasmedbio.2024.02.012","journal-title":"Ultrasound Med Biol"},{"key":"7283_CR27","doi-asserted-by":"publisher","first-page":"103","DOI":"10.1007\/s10895-011-0934-z","volume":"22","author":"X Gao","year":"2012","unstructured":"Gao X, Niu L, Su X (2012) Detection of DNA via the fluorescence quenching of Mn-doped ZnSe D-dots\/doxorubicin\/DNA ternary complexes system. J Fluoresc 22:103\u2013109. https:\/\/doi.org\/10.1007\/s10895-011-0934-z","journal-title":"J Fluoresc"},{"key":"7283_CR28","doi-asserted-by":"publisher","first-page":"300","DOI":"10.1016\/j.bios.2014.03.076","volume":"59","author":"Y Miao","year":"2014","unstructured":"Miao Y, Zhang Z, Gong Y, Yan G (2014) Phosphorescent quantum dots\/doxorubicin nanohybrids based on photoinduced electron transfer for detection of DNA. Biosens Bioelectron 59:300\u2013306. https:\/\/doi.org\/10.1016\/j.bios.2014.03.076","journal-title":"Biosens Bioelectron"},{"key":"7283_CR29","doi-asserted-by":"publisher","first-page":"138","DOI":"10.1016\/S1005-9040(07)60029-4","volume":"23","author":"Q Liao","year":"2007","unstructured":"Liao Q, Li Y, Huang C (2007) CdS quantum dots as fluorescence probes for detection of adriamycin hydrochloride. Chem Res Chin Univ 23:138\u2013142. https:\/\/doi.org\/10.1016\/S1005-9040(07)60029-4","journal-title":"Chem Res Chin Univ"},{"key":"7283_CR30","doi-asserted-by":"publisher","first-page":"169","DOI":"10.1016\/j.materresbull.2015.02.050","volume":"66","author":"X Yang","year":"2015","unstructured":"Yang X, Lin J, Liao X et al (2015) Interactions between N-acetyl-l-cysteine protected CdTe quantum dots and doxorubicin through spectroscopic method. Mater Res Bull 66:169\u2013175. https:\/\/doi.org\/10.1016\/j.materresbull.2015.02.050","journal-title":"Mater Res Bull"},{"key":"7283_CR31","doi-asserted-by":"publisher","first-page":"122200","DOI":"10.1016\/j.saa.2022.122200","volume":"288","author":"A Mohammadinejad","year":"2023","unstructured":"Mohammadinejad A, Abnous K, AlinezhadNameghi M et al (2023) Application of green-synthesized carbon dots for imaging of cancerous cell lines and detection of anthraquinone drugs using silica-coated CdTe quantum dots-based ratiometric fluorescence sensor. Spectrochim Acta A Mol Biomol Spectrosc 288:122200. https:\/\/doi.org\/10.1016\/j.saa.2022.122200","journal-title":"Spectrochim Acta A Mol Biomol Spectrosc"},{"key":"7283_CR32","doi-asserted-by":"publisher","first-page":"414283","DOI":"10.1016\/j.physb.2022.414283","volume":"645","author":"GR Bardajee","year":"2022","unstructured":"Bardajee GR, Sharifi M, Khanahmadi M (2022) An efficient method for detection of Epirubicin via Gelatin-CdTe\/ZnS QDs as a nano-bioconjugated fluorescent sensor. Physica B Condens Matter 645:414283. https:\/\/doi.org\/10.1016\/j.physb.2022.414283","journal-title":"Physica B Condens Matter"},{"key":"7283_CR33","doi-asserted-by":"publisher","first-page":"4681","DOI":"10.1016\/j.bios.2011.05.016","volume":"26","author":"S Raichlin","year":"2011","unstructured":"Raichlin S, Sharon E, Freeman R et al (2011) Electron-transfer quenching of nucleic acid-functionalized CdSe\/ZnS quantum dots by doxorubicin: a versatile system for the optical detection of DNA, aptamer\u2013substrate complexes and telomerase activity. Biosens Bioelectron 26:4681\u20134689. https:\/\/doi.org\/10.1016\/j.bios.2011.05.016","journal-title":"Biosens Bioelectron"},{"key":"7283_CR34","doi-asserted-by":"publisher","first-page":"152278","DOI":"10.1016\/j.cej.2024.152278","volume":"492","author":"DD Drozd","year":"2024","unstructured":"Drozd DD, Strokin PD, Kornilov DA et al (2024) Enhancement of the alloyed CdZnSeS\/ZnS quantum dots photoluminescence by thiol ligands capping. Chem Eng J 492:152278. https:\/\/doi.org\/10.1016\/j.cej.2024.152278","journal-title":"Chem Eng J"},{"key":"7283_CR35","doi-asserted-by":"publisher","first-page":"4471","DOI":"10.1007\/s00216-022-04016-4","volume":"414","author":"DD Drozd","year":"2022","unstructured":"Drozd DD, Byzova NA, Pidenko PS et al (2022) Luminescent alloyed quantum dots for turn-off enzyme-based assay. Anal Bioanal Chem 414:4471\u20134480. https:\/\/doi.org\/10.1007\/s00216-022-04016-4","journal-title":"Anal Bioanal Chem"},{"key":"7283_CR36","doi-asserted-by":"publisher","first-page":"24575","DOI":"10.1021\/acsami.0c05099","volume":"12","author":"OA Goryacheva","year":"2020","unstructured":"Goryacheva OA, Guhrenz C, Schneider K et al (2020) Silanized luminescent quantum dots for the simultaneous multicolor lateral flow immunoassay of two mycotoxins. ACS Appl Mater Interfaces 12:24575\u201324584. https:\/\/doi.org\/10.1021\/acsami.0c05099","journal-title":"ACS Appl Mater Interfaces"},{"key":"7283_CR37","doi-asserted-by":"publisher","unstructured":"Goryacheva OA, Kokorina AA, Podkolodnaya YA et al (2023) Express test for NT-proBNP competitive detection based on lateral flow immunoassay using silanized fluorescent quantum dots. Talanta Open 7. https:\/\/doi.org\/10.1016\/j.talo.2023.100186","DOI":"10.1016\/j.talo.2023.100186"},{"key":"7283_CR38","doi-asserted-by":"publisher","first-page":"3065","DOI":"10.1021\/nl071546n","volume":"7","author":"V Bagalkot","year":"2007","unstructured":"Bagalkot V, Zhang L, Levy-Nissenbaum E et al (2007) Quantum dot\u2212aptamer conjugates for synchronous cancer imaging, therapy, and sensing of drug delivery based on bi-fluorescence resonance energy transfer. Nano Lett 7:3065\u20133070. https:\/\/doi.org\/10.1021\/nl071546n","journal-title":"Nano Lett"},{"key":"7283_CR39","doi-asserted-by":"publisher","first-page":"117774","DOI":"10.1016\/j.trac.2024.117774","volume":"177","author":"DV Tsyupka","year":"2024","unstructured":"Tsyupka DV, Podkolodnaya YA, Khudina EA et al (2024) Anthracycline antibiotics detection using turn-off luminescent nanosensors. TrAC Trends Anal Chem 177:117774. https:\/\/doi.org\/10.1016\/j.trac.2024.117774","journal-title":"TrAC Trends Anal Chem"},{"key":"7283_CR40","doi-asserted-by":"publisher","first-page":"596","DOI":"10.3390\/bios13060596","volume":"13","author":"SA Mescheryakova","year":"2023","unstructured":"Mescheryakova SA, Matlakhov IS, Strokin PD et al (2023) Fluorescent alloyed CdZnSeS\/ZnS nanosensor for doxorubicin detection. Biosensors (Basel) 13:596. https:\/\/doi.org\/10.3390\/bios13060596","journal-title":"Biosensors (Basel)"},{"key":"7283_CR41","doi-asserted-by":"publisher","first-page":"3431","DOI":"10.1021\/ac2000303","volume":"83","author":"C W\u00fcrth","year":"2011","unstructured":"W\u00fcrth C, Grabolle M, Pauli J et al (2011) Comparison of methods and achievable uncertainties for the relative and absolute measurement of photoluminescence quantum yields. Anal Chem 83:3431\u20133439. https:\/\/doi.org\/10.1021\/ac2000303","journal-title":"Anal Chem"},{"key":"7283_CR42","doi-asserted-by":"publisher","first-page":"1","DOI":"10.13140\/RG.2.2.16547.30244","volume":"68","author":"RM Williams","year":"2007","unstructured":"Williams RM (2007) Introduction to electron transfer. Photosynth Res 68:1\u201328. https:\/\/doi.org\/10.13140\/RG.2.2.16547.30244","journal-title":"Photosynth Res"},{"key":"7283_CR43","doi-asserted-by":"publisher","first-page":"8414","DOI":"10.1039\/D1CS00422K","volume":"50","author":"D Genovese","year":"2021","unstructured":"Genovese D, Cingolani M, Rampazzo E et al (2021) Static quenching upon adduct formation: a treatment without shortcuts and approximations. Chem Soc Rev 50:8414\u20138427. https:\/\/doi.org\/10.1039\/D1CS00422K","journal-title":"Chem Soc Rev"},{"key":"7283_CR44","doi-asserted-by":"publisher","first-page":"97","DOI":"10.3109\/17435390.2011.634079","volume":"7","author":"Y Liu","year":"2013","unstructured":"Liu Y, Ji F, Liu R (2013) The interaction of bovine serum albumin with doxorubicin-loaded superparamagnetic iron oxide nanoparticles: spectroscope and molecular modelling identification. Nanotoxicology 7:97\u2013104. https:\/\/doi.org\/10.3109\/17435390.2011.634079","journal-title":"Nanotoxicology"},{"key":"7283_CR45","doi-asserted-by":"publisher","first-page":"5019","DOI":"10.1016\/j.scitotenv.2009.05.052","volume":"407","author":"L Zhao","year":"2009","unstructured":"Zhao L, Liu R, Zhao X et al (2009) New strategy for the evaluation of CdTe quantum dot toxicity targeted to bovine serum albumin. Sci Total Environ 407:5019\u20135023. https:\/\/doi.org\/10.1016\/j.scitotenv.2009.05.052","journal-title":"Sci Total Environ"},{"key":"7283_CR46","doi-asserted-by":"publisher","first-page":"131648","DOI":"10.1016\/j.colsurfa.2023.131648","volume":"671","author":"DV Tsyupka","year":"2023","unstructured":"Tsyupka DV, Mordovina EA, Ponomaryova TS et al (2023) Luminescence behavior of colloid quantum dots in the presence anthracycline antibiotic mitoxantrone: surface interaction and luminescence quenching, size and composition dependence, potential for clinical study. Colloids Surf A Physicochem Eng Asp 671:131648. https:\/\/doi.org\/10.1016\/j.colsurfa.2023.131648","journal-title":"Colloids Surf A Physicochem Eng Asp"},{"key":"7283_CR47","doi-asserted-by":"publisher","first-page":"1083","DOI":"10.1002\/bio.2862","volume":"30","author":"O Bunkoed","year":"2015","unstructured":"Bunkoed O, Kanatharana P (2015) Mercaptopropionic acid\u2013capped CdTe quantum dots as fluorescence probe for the determination of salicylic acid in pharmaceutical products. Luminescence 30:1083\u20131089. https:\/\/doi.org\/10.1002\/bio.2862","journal-title":"Luminescence"},{"key":"7283_CR48","doi-asserted-by":"publisher","DOI":"10.1007\/978-0-387-46312-4","volume-title":"Principles of fluorescence spectroscopy","author":"JR Lakowicz","year":"2006","unstructured":"Lakowicz JR (2006) Principles of fluorescence spectroscopy. Springer, Boston"},{"key":"7283_CR49","doi-asserted-by":"publisher","first-page":"597","DOI":"10.1016\/j.jlumin.2010.10.037","volume":"131","author":"S Jagadeeswari","year":"2011","unstructured":"Jagadeeswari S, Asha Jhonsi M, Kathiravan A, Renganathan R (2011) Photoinduced interaction between MPA capped CdTe QDs and certain anthraquinone dyes. J Lumin 131:597\u2013602. https:\/\/doi.org\/10.1016\/j.jlumin.2010.10.037","journal-title":"J Lumin"},{"key":"7283_CR50","doi-asserted-by":"publisher","first-page":"2484","DOI":"10.1016\/j.jlumin.2012.03.072","volume":"132","author":"Z Liu","year":"2012","unstructured":"Liu Z, Yin P, Gong H et al (2012) Determination of rifampicin based on fluorescence quenching of GSH capped CdTe\/ZnS QDs. J Lumin 132:2484\u20132488. https:\/\/doi.org\/10.1016\/j.jlumin.2012.03.072","journal-title":"J Lumin"},{"key":"7283_CR51","doi-asserted-by":"publisher","first-page":"32","DOI":"10.3390\/nano9010032","volume":"9","author":"Z Wang","year":"2018","unstructured":"Wang Z, Xiao X, Zou T et al (2018) Citric acid capped CdS quantum dots for fluorescence detection of copper ions (II) in aqueous solution. Nanomaterials 9:32. https:\/\/doi.org\/10.3390\/nano9010032","journal-title":"Nanomaterials"},{"key":"7283_CR52","doi-asserted-by":"publisher","first-page":"195501","DOI":"10.1088\/0957-4484\/25\/19\/195501","volume":"25","author":"MJ Ruedas-Rama","year":"2014","unstructured":"Ruedas-Rama MJ, Hall EAH (2014) pH sensitive quantum dot\u2013anthraquinone nanoconjugates. Nanotechnology 25:195501. https:\/\/doi.org\/10.1088\/0957-4484\/25\/19\/195501","journal-title":"Nanotechnology"},{"key":"7283_CR53","doi-asserted-by":"publisher","unstructured":"Eksborg S, Ehrsson H, Ekqvist B (1982) Protein binding of anthraquinone glycosides, with special reference to adriamycin. Cancer Chemother Pharmacol 10. https:\/\/doi.org\/10.1007\/BF00257228","DOI":"10.1007\/BF00257228"},{"key":"7283_CR54","first-page":"3417","volume":"43","author":"RF Greene","year":"1983","unstructured":"Greene RF, Collins JM, Jenkins JF et al (1983) Plasma pharmacokinetics of adriamycin and adriamycinol: implications for the design of in vitro experiments and treatment protocols. Cancer Res 43:3417\u20133421","journal-title":"Cancer Res"},{"key":"7283_CR55","doi-asserted-by":"publisher","first-page":"571","DOI":"10.1007\/s002800050529","volume":"38","author":"O Chassany","year":"1996","unstructured":"Chassany O, Urien S, Claudepierre P et al (1996) Comparative serum protein binding of anthracycline derivatives. Cancer Chemother Pharmacol 38:571\u2013573. https:\/\/doi.org\/10.1007\/s002800050529","journal-title":"Cancer Chemother Pharmacol"},{"key":"7283_CR56","doi-asserted-by":"publisher","first-page":"115","DOI":"10.2174\/138920010791110890","volume":"11","author":"S Lal","year":"2010","unstructured":"Lal S, Mahajan A, Chen WN, Chowbay B (2010) Pharmacogenetics of target genes across doxorubicin disposition pathway: a review. Curr Drug Metab 11:115\u2013128. https:\/\/doi.org\/10.2174\/138920010791110890","journal-title":"Curr Drug Metab"},{"key":"7283_CR57","doi-asserted-by":"publisher","unstructured":"Pippa LF, Oliveira ML de, Rocha A, et al (2020) Total, renal and hepatic clearances of doxorubicin and formation clearance of doxorubicinol in patients with breast cancer: Estimation of doxorubicin hepatic extraction ratio. J Pharm Biomed Anal 185. https:\/\/doi.org\/10.1016\/j.jpba.2020.113231","DOI":"10.1016\/j.jpba.2020.113231"},{"key":"7283_CR58","doi-asserted-by":"publisher","first-page":"1252","DOI":"10.1002\/bmc.1054","volume":"22","author":"G Wei","year":"2008","unstructured":"Wei G, Xiao S, Si D, Liu C (2008) Improved HPLC method for doxorubicin quantification in rat plasma to study the pharmacokinetics of micelle-encapsulated and liposome-encapsulated doxorubicin formulations. Biomed Chromatogr 22:1252\u20131258. https:\/\/doi.org\/10.1002\/bmc.1054","journal-title":"Biomed Chromatogr"}],"container-title":["Microchimica Acta"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00604-025-07283-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00604-025-07283-x\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00604-025-07283-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,6]],"date-time":"2025-09-06T19:13:01Z","timestamp":1757185981000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00604-025-07283-x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,6,12]]},"references-count":58,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2025,7]]}},"alternative-id":["7283"],"URL":"https:\/\/doi.org\/10.1007\/s00604-025-07283-x","relation":{},"ISSN":["0026-3672","1436-5073"],"issn-type":[{"value":"0026-3672","type":"print"},{"value":"1436-5073","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,6,12]]},"assertion":[{"value":"7 April 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"26 May 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"12 June 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The research volunteer blood plasma was used for the experiments of Dox detection. Protocol no. 8 from 02.03.2021, Saratov State Medical University named after V.I. Razumovsky.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval"}},{"value":"The authors declare no competing interests.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"416"}}