{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T17:46:18Z","timestamp":1791999978474,"version":"4.4.0"},"reference-count":32,"publisher":"Springer Science and Business Media LLC","issue":"11","license":[{"start":{"date-parts":[[2025,10,16]],"date-time":"2025-10-16T00:00:00Z","timestamp":1760572800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2025,10,16]],"date-time":"2025-10-16T00:00:00Z","timestamp":1760572800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Microchim Acta"],"published-print":{"date-parts":[[2025,11]]},"DOI":"10.1007\/s00604-025-07605-z","type":"journal-article","created":{"date-parts":[[2025,10,16]],"date-time":"2025-10-16T01:51:31Z","timestamp":1760579491000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Four-channel carbon dot fluorescent sensor array with a pattern recognition approach for the discrimination and quantification of rifamycin antibiotics"],"prefix":"10.1007","volume":"192","author":[{"given":"Yichen","family":"Li","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qianqian","family":"Jiang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhixiang","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuaijing","family":"Du","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yingxiang","family":"Du","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,10,16]]},"reference":[{"key":"7605_CR1","doi-asserted-by":"publisher","first-page":"1111","DOI":"10.1126\/science.abq2787","volume":"378","author":"Q Liu","year":"2022","unstructured":"Liu Q, Zhu J, Dulberger CL et al (2022) Tuberculosis treatment failure associated with evolution of antibiotic resilience. Science 378:1111\u20131118. https:\/\/doi.org\/10.1126\/science.abq2787","journal-title":"Science"},{"key":"7605_CR2","doi-asserted-by":"publisher","first-page":"657","DOI":"10.1186\/s12879-024-09514-7","volume":"24","author":"N Zinyakatira","year":"2024","unstructured":"Zinyakatira N, Ford N, Cox H (2024) Association between HIV and acquisition of rifamycin resistance with first-line TB treatment: a systematic review and meta-analysis. BMC Infect Dis 24:657. https:\/\/doi.org\/10.1186\/s12879-024-09514-7","journal-title":"BMC Infect Dis"},{"key":"7605_CR3","doi-asserted-by":"publisher","first-page":"1298749","DOI":"10.3389\/fimmu.2024.1298749","volume":"15","author":"X Li","year":"2024","unstructured":"Li X, Ma Y, Li G et al (2024) Leprosy: treatment, prevention, immune response and gene function. Front Immunol 15:1298749. https:\/\/doi.org\/10.3389\/fimmu.2024.1298749","journal-title":"Front Immunol"},{"key":"7605_CR4","doi-asserted-by":"publisher","first-page":"3151","DOI":"10.1016\/j.molcel.2022.06.019","volume":"82","author":"MD Surette","year":"2022","unstructured":"Surette MD, Waglechner N, Koteva K, Wright GD (2022) HelR is a helicase-like protein that protects RNA polymerase from rifamycin antibiotics. Mol Cell 82:3151\u20133165. https:\/\/doi.org\/10.1016\/j.molcel.2022.06.019","journal-title":"Mol Cell"},{"key":"7605_CR5","doi-asserted-by":"publisher","first-page":"2042","DOI":"10.1126\/science.1063814","volume":"295","author":"C Dye","year":"2002","unstructured":"Dye C, Williams BG, Espinal MA, Raviglione MC (2002) Erasing the world\u2019s slow stain: strategies to beat multidrug-resistant tuberculosis. Science 295:2042\u20132046. https:\/\/doi.org\/10.1126\/science.1063814","journal-title":"Science"},{"key":"7605_CR6","doi-asserted-by":"publisher","first-page":"969","DOI":"10.1038\/s41586-024-08095-4","volume":"635","author":"AM Turner","year":"2024","unstructured":"Turner AM, Li L, Monk IR et al (2024) Rifaximin prophylaxis causes resistance to the last-resort antibiotic daptomycin. Nature 635:969\u2013977. https:\/\/doi.org\/10.1038\/s41586-024-08095-4","journal-title":"Nature"},{"key":"7605_CR7","unstructured":"State Council of China (2020) Regulations on the management of veterinary drugs of the People\u2019s Republic of China.\u00a0https:\/\/flk.npc.gov.cn\/detail?id=ff808081777d07c50177b80b86032a90. Accessed\u00a02025-04-03"},{"key":"7605_CR8","doi-asserted-by":"publisher","first-page":"100437","DOI":"10.1016\/j.afres.2024.100437","volume":"4","author":"SL Abey","year":"2024","unstructured":"Abey SL, Gedefaw M, Molla W et al (2024) Molecular detection and antimicrobial resistance profile of Salmonella isolated from humans, animals, abattoir equipment and environment. Applied Food Research 4:100437. https:\/\/doi.org\/10.1016\/j.afres.2024.100437","journal-title":"Applied Food Research"},{"key":"7605_CR9","doi-asserted-by":"publisher","first-page":"176280","DOI":"10.1016\/j.scitotenv.2024.176280","volume":"954","author":"L Albarano","year":"2024","unstructured":"Albarano L, Padilla Suarez EG, Maggio C et al (2024) Assessment of ecological risks posed by veterinary antibiotics in European aquatic environments: a comprehensive review and analysis. Sci Total Environ 954:176280. https:\/\/doi.org\/10.1016\/j.scitotenv.2024.176280","journal-title":"Sci Total Environ"},{"key":"7605_CR10","doi-asserted-by":"publisher","first-page":"109603","DOI":"10.1016\/j.envint.2025.109339","volume":"197","author":"K Mi","year":"2025","unstructured":"Mi K, Wu X, Lin Z (2025) Chemical risk assessment in food animals via physiologically based pharmacokinetic modeling \u2212 part I: veterinary drugs on human food safety assessment. Environ Int 197:109603. https:\/\/doi.org\/10.1016\/j.envint.2025.109339","journal-title":"Environ Int"},{"key":"7605_CR11","doi-asserted-by":"publisher","first-page":"2392","DOI":"10.1021\/acs.analchem.5b04409","volume":"88","author":"CW Chumbley","year":"2016","unstructured":"Chumbley CW, Reyzer ML, Allen JL et al (2016) Absolute quantitative MALDI imaging mass spectrometry: a case of rifampicin in liver tissues. Anal Chem 88:2392\u20132398. https:\/\/doi.org\/10.1021\/acs.analchem.5b04409","journal-title":"Anal Chem"},{"key":"7605_CR12","doi-asserted-by":"publisher","first-page":"400","DOI":"10.1016\/j.apsusc.2015.12.149","volume":"364","author":"O Ivashchenko","year":"2016","unstructured":"Ivashchenko O, Jurga-Stopa J, Coy E et al (2016) Fourier transform infrared and Raman spectroscopy studies on magnetite\/Ag\/antibiotic nanocomposites. Appl Surf Sci 364:400\u2013409. https:\/\/doi.org\/10.1016\/j.apsusc.2015.12.149","journal-title":"Appl Surf Sci"},{"key":"7605_CR13","doi-asserted-by":"publisher","first-page":"4599","DOI":"10.3390\/molecules29194599","volume":"29","author":"L-P Fan","year":"2024","unstructured":"Fan L-P, Tao Q, Wang X-Q et al (2024) Development of a method for the determination of rifaximin and rifampicin residues in foods of animal origin. Molecules 29:4599. https:\/\/doi.org\/10.3390\/molecules29194599","journal-title":"Molecules"},{"key":"7605_CR14","doi-asserted-by":"publisher","first-page":"7105","DOI":"10.1039\/c7cs00240h","volume":"46","author":"D Wu","year":"2017","unstructured":"Wu D, Sedgwick AC, Gunnlaugsson T et al (2017) Fluorescent chemosensors: the past, present and future. Chem Soc Rev 46:7105\u20137123. https:\/\/doi.org\/10.1039\/c7cs00240h","journal-title":"Chem Soc Rev"},{"key":"7605_CR15","doi-asserted-by":"publisher","first-page":"143768","DOI":"10.1016\/j.molstruc.2025.143768","volume":"1349","author":"X Zhang","year":"2026","unstructured":"Zhang X, Hu Y, Hu B, Zhou M (2026) Spectral and structural study of a water-soluble macrocyclic fluorescent probe for the recognition of zinc ions. J Mol Struct 1349:143768. https:\/\/doi.org\/10.1016\/j.molstruc.2025.143768","journal-title":"J Mol Struct"},{"key":"7605_CR16","doi-asserted-by":"publisher","first-page":"116944","DOI":"10.1016\/j.foodres.2025.116944","volume":"218","author":"H Jia","year":"2025","unstructured":"Jia H, Xiong S, Yu X et al (2025) Rapid detection of aspartame in beverages using a molecularly imprinted polymer-based fluorescence sensor. Food Res Int 218:116944. https:\/\/doi.org\/10.1016\/j.foodres.2025.116944","journal-title":"Food Res Int"},{"key":"7605_CR17","doi-asserted-by":"publisher","first-page":"107762","DOI":"10.1016\/j.jfca.2025.107762","volume":"145","author":"Y He","year":"2025","unstructured":"He Y, Lv C, Li F et al (2025) Simultaneous detection of two pesticides by colorimetric and fluorescence dual-response sensor based on aptamer and gold nanoparticles. J Food Compost Anal 145:107762. https:\/\/doi.org\/10.1016\/j.jfca.2025.107762","journal-title":"J Food Compost Anal"},{"key":"7605_CR18","doi-asserted-by":"publisher","first-page":"188","DOI":"10.1016\/j.mattod.2021.07.028","volume":"51","author":"S Li","year":"2021","unstructured":"Li S, Li L, Tu H et al (2021) The development of carbon dots: from the perspective of materials chemistry. Mater Today 51:188\u2013207. https:\/\/doi.org\/10.1016\/j.mattod.2021.07.028","journal-title":"Mater Today"},{"key":"7605_CR19","doi-asserted-by":"publisher","first-page":"202318483","DOI":"10.1002\/anie.202318483","volume":"63","author":"Y Yu","year":"2024","unstructured":"Yu Y, Ni W, Hu Q et al (2024) A dual fluorescence turn-on sensor array formed by poly(para-aryleneethynylene) and aggregation-induced emission fluorophores for sensitive multiplexed bacterial recognition. Angew Chem Int Ed 63:202318483. https:\/\/doi.org\/10.1002\/anie.202318483","journal-title":"Angew Chem Int Ed"},{"key":"7605_CR20","doi-asserted-by":"publisher","first-page":"8917","DOI":"10.1021\/jacs.2c12798","volume":"145","author":"X-L Hu","year":"2023","unstructured":"Hu X-L, Gan H-Q, Qin Z-Y et al (2023) Phenotyping of methicillin-resistant Staphylococcus aureus using a ratiometric sensor array. J Am Chem Soc 145:8917\u20138926. https:\/\/doi.org\/10.1021\/jacs.2c12798","journal-title":"J Am Chem Soc"},{"key":"7605_CR21","doi-asserted-by":"publisher","first-page":"451","DOI":"10.1007\/s00604-023-06021-5","volume":"190","author":"C Yang","year":"2023","unstructured":"Yang C, Zhang H (2023) A review on machine learning\u2013powered fluorescent and colorimetric sensor arrays for bacteria identification. Microchim Acta 190:451. https:\/\/doi.org\/10.1007\/s00604-023-06021-5","journal-title":"Microchim Acta"},{"key":"7605_CR22","doi-asserted-by":"publisher","first-page":"4224","DOI":"10.1021\/acs.analchem.3c05582","volume":"96","author":"X Zhou","year":"2024","unstructured":"Zhou X, Huang S, Liu W, Shang L (2024) Metal ion-regulated fluorescent sensor array based on gold nanoclusters for physiological phosphate sensing. Anal Chem 96:4224\u20134231. https:\/\/doi.org\/10.1021\/acs.analchem.3c05582","journal-title":"Anal Chem"},{"key":"7605_CR23","doi-asserted-by":"publisher","first-page":"e126608","DOI":"10.1016\/j.talanta.2024.126608","volume":"279","author":"X Yin","year":"2024","unstructured":"Yin X, Zhong Y, Chen A et al (2024) A triple-channel sensor array utilizing fluorescent carbon dots for simultaneous discrimination and detection of multiple fluoroquinolones. Talanta 279:e126608. https:\/\/doi.org\/10.1016\/j.talanta.2024.126608","journal-title":"Talanta"},{"key":"7605_CR24","doi-asserted-by":"publisher","first-page":"113694","DOI":"10.1016\/j.jphotochem.2021.113694","volume":"425","author":"R Shokri","year":"2022","unstructured":"Shokri R, Amjadi M (2022) Boron and nitrogen co-doped carbon dots as a chemiluminescence probe for sensitive assay of rifampicin. J Photochem Photobiol A Chem 425:113694. https:\/\/doi.org\/10.1016\/j.jphotochem.2021.113694","journal-title":"J Photochem Photobiol A Chem"},{"key":"7605_CR25","doi-asserted-by":"publisher","first-page":"115800","DOI":"10.1016\/j.optmat.2024.115800","volume":"155","author":"J Su","year":"2024","unstructured":"Su J, Wu L, Zhu Y et al (2024) Nitrogen\u2013silicon co-doped carbon dots synthesized based on lemon peel for copper (II) detection via a dynamic quenching mechanism. Opt Mater 155:115800. https:\/\/doi.org\/10.1016\/j.optmat.2024.115800","journal-title":"Opt Mater"},{"key":"7605_CR26","doi-asserted-by":"publisher","first-page":"342182","DOI":"10.1016\/j.aca.2023.342182","volume":"1289","author":"J Wang","year":"2024","unstructured":"Wang J, Sun Y, Wang P et al (2024) A dual-emitting fluoroprobe fabricated by aloe leaf-based N-doped carbon quantum dots and copper nanoclusters for nitenpyram detection in waters by virtue of inner filter effect and static quenching principles. Anal Chim Acta 1289:342182. https:\/\/doi.org\/10.1016\/j.aca.2023.342182","journal-title":"Anal Chim Acta"},{"key":"7605_CR27","doi-asserted-by":"publisher","first-page":"160902","DOI":"10.1016\/j.cej.2025.160902","volume":"509","author":"P Wei","year":"2025","unstructured":"Wei P, Han W, Xie L et al (2025) Research progress on nanomaterial-based electrochemical sensors for the detection of aflatoxin B1 in food and environmental samples. Chem Eng J 509:160902. https:\/\/doi.org\/10.1016\/j.cej.2025.160902","journal-title":"Chem Eng J"},{"key":"7605_CR28","doi-asserted-by":"publisher","first-page":"216907","DOI":"10.1016\/j.ccr.2025.216907","volume":"543","author":"L Wang","year":"2025","unstructured":"Wang L, Chang S-J, Chen C-J, Liu J-T (2025) Metal-organic frameworks for electrochemical glucose sensors: progress and challenges. Coord Chem Rev 543:216907. https:\/\/doi.org\/10.1016\/j.ccr.2025.216907","journal-title":"Coord Chem Rev"},{"key":"7605_CR29","doi-asserted-by":"publisher","first-page":"711","DOI":"10.1007\/s00604-024-06774-7","volume":"191","author":"S Yang","year":"2024","unstructured":"Yang S, Tian L, Feng Y et al (2024) Molecularly imprinted electrochemiluminescence sensor based on luminol functionalized Co-MOF for rifampicin detection. Microchim Acta 191:711. https:\/\/doi.org\/10.1007\/s00604-024-06774-7","journal-title":"Microchim Acta"},{"key":"7605_CR30","doi-asserted-by":"publisher","first-page":"110115","DOI":"10.1016\/j.microc.2024.110115","volume":"199","author":"J Arumugam","year":"2024","unstructured":"Arumugam J, Shanmugam G, Venkatesan M, Sreedhar S (2024) Synergistic activity of copper and molybdenum based organic frameworks for the exceptional electrochemical detection of rifampicin in commercial dairy products. Microchem J 199:110115. https:\/\/doi.org\/10.1016\/j.microc.2024.110115","journal-title":"Microchem J"},{"key":"7605_CR31","doi-asserted-by":"publisher","first-page":"100383","DOI":"10.1016\/j.mtadv.2023.100383","volume":"18","author":"X Tang","year":"2023","unstructured":"Tang X, Zhao Y, Yu H et al (2023) Concentration-regulated multi-color fluorescent carbon dots for the detection of rifampicin, morin and Al3+. Mater Today Adv 18:100383. https:\/\/doi.org\/10.1016\/j.mtadv.2023.100383","journal-title":"Mater Today Adv"},{"key":"7605_CR32","doi-asserted-by":"publisher","first-page":"121944","DOI":"10.1016\/j.saa.2022.121944","volume":"286","author":"Y Zhang","year":"2023","unstructured":"Zhang Y, Deng Q, Tang C et al (2023) Fluorescent folic acid-capped copper nanoclusters for the determination of rifampicin based on inner filter effect. Spectrochim Acta A Mol Biomol Spectrosc 286:121944. https:\/\/doi.org\/10.1016\/j.saa.2022.121944","journal-title":"Spectrochim Acta A Mol Biomol Spectrosc"}],"container-title":["Microchimica Acta"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00604-025-07605-z.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00604-025-07605-z\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00604-025-07605-z.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,11]],"date-time":"2025-11-11T16:11:47Z","timestamp":1762877507000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00604-025-07605-z"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,10,16]]},"references-count":32,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2025,11]]}},"alternative-id":["7605"],"URL":"https:\/\/doi.org\/10.1007\/s00604-025-07605-z","relation":{},"ISSN":["0026-3672","1436-5073"],"issn-type":[{"value":"0026-3672","type":"print"},{"value":"1436-5073","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,10,16]]},"assertion":[{"value":"15 August 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"26 September 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"16 October 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"738"}}