{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T20:34:42Z","timestamp":1791232482544,"version":"4.1.0"},"reference-count":31,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2025,12,3]],"date-time":"2025-12-03T00:00:00Z","timestamp":1764720000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2025,12,3]],"date-time":"2025-12-03T00:00:00Z","timestamp":1764720000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"DOI":"10.13039\/501100007128","name":"Natural Science Foundation of Shaanxi Province","doi-asserted-by":"publisher","award":["2024JC-YBMS-116"],"award-info":[{"award-number":["2024JC-YBMS-116"]}],"id":[{"id":"10.13039\/501100007128","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Microchim Acta"],"published-print":{"date-parts":[[2026,1]]},"DOI":"10.1007\/s00604-025-07735-4","type":"journal-article","created":{"date-parts":[[2025,12,3]],"date-time":"2025-12-03T19:13:27Z","timestamp":1764789207000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Tetrakis(4-pyridylphenyl)ethylene-decorated metal-organic frameworks with aggregation-induced chemiluminescence emission on paper-based platform for volatile sulfur compounds measurement"],"prefix":"10.1007","volume":"193","author":[{"given":"Huaqin","family":"Shui","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yanli","family":"Guo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jingbo","family":"Geng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qing","family":"Chang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuxin","family":"Tian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xue","family":"Du","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yan","family":"Jin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Baoxin","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,12,3]]},"reference":[{"issue":"4","key":"7735_CR1","doi-asserted-by":"publisher","first-page":"100623","DOI":"10.1016\/j.bj.2023.100623","volume":"46","author":"PC Moura","year":"2023","unstructured":"Moura PC, Raposo M, Vassilenko V (2023) Breath volatile organic compounds (VOCs) as biomarkers for the diagnosis of pathological conditions: a review. Biomed J 46(4):100623. https:\/\/doi.org\/10.1016\/j.bj.2023.100623","journal-title":"Biomed J"},{"key":"7735_CR2","doi-asserted-by":"publisher","first-page":"61","DOI":"10.1016\/j.cca.2020.12.036","volume":"515","author":"T Chen","year":"2021","unstructured":"Chen T, Liu TN, Li T, Zhao H, Chen QM (2021) Exhaled breath analysis in disease detection. Clin Chim Acta 515:61\u201372. https:\/\/doi.org\/10.1016\/j.cca.2020.12.036","journal-title":"Clin Chim Acta"},{"issue":"16","key":"7735_CR3","doi-asserted-by":"publisher","first-page":"5258","DOI":"10.3390\/molecules27165258","volume":"27","author":"MA Floss","year":"2022","unstructured":"Floss MA, Fink T, Maurer F, Volk T, Kreuer S, M\u00fcller-Wirtz LM (2022) Exhaled aldehydes as biomarkers for lung diseases: a narrative review. Molecules 27(16):5258. https:\/\/doi.org\/10.3390\/molecules27165258","journal-title":"Molecules"},{"issue":"8","key":"7735_CR4","doi-asserted-by":"publisher","first-page":"5116","DOI":"10.1021\/acs.analchem.8b05670","volume":"91","author":"R Kalidoss","year":"2019","unstructured":"Kalidoss R, Umapathy S, Anandan R, Ganesh V, Sivalingam Y (2019) Comparative study on the preparation and gas sensing properties of reduced graphene oxide\/SnO2 binary nanocomposite for detection of acetone in exhaled breath. Anal Chem 91(8):5116\u20135124. https:\/\/doi.org\/10.1021\/acs.analchem.8b05670","journal-title":"Anal Chem"},{"key":"7735_CR5","doi-asserted-by":"publisher","first-page":"787908","DOI":"10.3389\/fnut.2021.787908","volume":"8","author":"N L\u00f3pez-Valverde","year":"2022","unstructured":"L\u00f3pez-Valverde N, L\u00f3pez-Valverde A, Sousa BMD, Rodr\u00edguez C, Su\u00e1rez A, Aragoneses JM (2022) Role of probiotics in halitosis of oral origin: a systematic review and meta-analysis of randomized clinical studies. Front Nutr 8:787908. https:\/\/doi.org\/10.3389\/fnut.2021.787908","journal-title":"Front Nutr"},{"issue":"15","key":"7735_CR6","doi-asserted-by":"publisher","first-page":"8769","DOI":"10.1021\/acs.analchem.8b01273","volume":"90","author":"JH Cha","year":"2018","unstructured":"Cha JH, Kim DH, Choi SJ, Koo WT, Kim ID (2018) Sub-parts-per-million hydrogen sulfide colorimetric sensor: lead acetate anchored nanofibers toward halitosis diagnosis. Anal Chem 90(15):8769\u20138775. https:\/\/doi.org\/10.1021\/acs.analchem.8b01273","journal-title":"Anal Chem"},{"issue":"36","key":"7735_CR7","doi-asserted-by":"publisher","first-page":"1700737","DOI":"10.1002\/adma.201700737","volume":"29","author":"SJ Kim","year":"2017","unstructured":"Kim SJ, Choi SJ, Jang JS, Cho HJ, Koo WT, Tuller HL, Kim ID (2017) Exceptional high-performance of Pt-based bimetallic catalysts for exclusive detection of exhaled biomarkers. Adv Mater 29(36):1700737. https:\/\/doi.org\/10.1002\/adma.201700737","journal-title":"Adv Mater"},{"key":"7735_CR8","doi-asserted-by":"publisher","first-page":"13175","DOI":"10.1038\/s41598-023-40391-3","volume":"13","author":"YH Lee","year":"2023","unstructured":"Lee YH, Shin SI, Hong JY (2023) Investigation of volatile sulfur compound level and halitosis in patients with gingivitis and periodontitis. Sci Rep 13:13175. https:\/\/doi.org\/10.1038\/s41598-023-40391-3","journal-title":"Sci Rep"},{"key":"7735_CR9","doi-asserted-by":"publisher","first-page":"342468","DOI":"10.1016\/j.aca.2024.342468","volume":"1301","author":"E Schulz","year":"2024","unstructured":"Schulz E, Woollam M, Vashistha S, Agarwal M (2024) Quantifying exhaled acetone and isoprene through solid phase microextraction and gas chromatography-mass spectrometry. Anal Chim Acta 1301:342468. https:\/\/doi.org\/10.1016\/j.aca.2024.342468","journal-title":"Anal Chim Acta"},{"key":"7735_CR10","doi-asserted-by":"publisher","first-page":"131008","DOI":"10.1016\/j.snb.2021.131008","volume":"352","author":"Y Hou","year":"2022","unstructured":"Hou Y, Lv CC, Liu W, Guo YL, Jin Y, Li BX, Zhang Y, Liu YC (2022) In situ synthesis of copper metal-organic framework on paper-based device for dual-mode detection of volatile sulfur compounds in exhaled breath. Sens Actuators B Chem 352:131008. https:\/\/doi.org\/10.1016\/j.snb.2021.131008","journal-title":"Sens Actuators B Chem"},{"issue":"3","key":"7735_CR11","doi-asserted-by":"publisher","first-page":"733","DOI":"10.1021\/acssensors.0c01280","volume":"6","author":"DL Feng","year":"2021","unstructured":"Feng DL, Du LL, Xing XX, Wang C, Chen J, Zhu ZY, Tian YT, Yang DC (2021) Highly sensitive and selective NiO\/WO3 composite nanoparticles in detecting H2S biomarker of halitosis. ACS Sens 6(3):733\u2013741. https:\/\/doi.org\/10.1021\/acssensors.0c01280","journal-title":"ACS Sens"},{"key":"7735_CR12","doi-asserted-by":"publisher","first-page":"131044","DOI":"10.1016\/j.seppur.2024.131044","volume":"360","author":"YS Wang","year":"2025","unstructured":"Wang YS, Duan MX, Su ZL, Yang C, Wang YX, Kou T, Kou JW, Fan HL (2025) Combination of adsorption and oxidation over Fe-doped Cu-1,3,5-benzenetricarboxylate to boost room temperature H2S removal. Sep Purif Technol 360:131044. https:\/\/doi.org\/10.1016\/j.seppur.2024.131044","journal-title":"Sep Purif Technol"},{"key":"7735_CR13","doi-asserted-by":"publisher","first-page":"140100","DOI":"10.1016\/j.foodchem.2024.140100","volume":"457","author":"XB Chen","year":"2024","unstructured":"Chen XB, Zhao JW, Wang Y, Yuan R, Chen SH (2024) Dual emitting aggregation-induced electrochemiluminescence from tetrastyrene derivative for chloramphenicol detection. Food Chem 457:140100. https:\/\/doi.org\/10.1016\/j.foodchem.2024.140100","journal-title":"Food Chem"},{"key":"7735_CR14","doi-asserted-by":"publisher","first-page":"125843","DOI":"10.1016\/j.talanta.2024.125843","volume":"273","author":"L Zhang","year":"2024","unstructured":"Zhang L, Bi XY, Wang H, Li LB, You TY (2024) Loading of AuNCs with AIE effect onto cerium-based MOFs to boost fluorescence for sensitive detection of Hg2+. Talanta 273:125843. https:\/\/doi.org\/10.1016\/j.talanta.2024.125843","journal-title":"Talanta"},{"issue":"2","key":"7735_CR15","doi-asserted-by":"publisher","first-page":"1351","DOI":"10.1021\/ac5041605","volume":"87","author":"LJ Zhang","year":"2015","unstructured":"Zhang LJ, He N, Lu C (2015) Aggregation-induced emission: a simple strategy to improve chemiluminescence resonance energy transfer. Anal Chem 87(2):1351\u20131357. https:\/\/doi.org\/10.1021\/ac5041605","journal-title":"Anal Chem"},{"key":"7735_CR16","doi-asserted-by":"publisher","first-page":"254","DOI":"10.1007\/s00604-021-04923-w","volume":"188","author":"HN Tan","year":"2021","unstructured":"Tan HN, Li YH (2021) Aiegens-based fluorescent covalent organic framework in construction of chemiluminescence resonance energy transfer system for serum uric acid detection. Microchim Acta 188:254. https:\/\/doi.org\/10.1007\/s00604-021-04923-w","journal-title":"Microchim Acta"},{"issue":"6","key":"7735_CR17","doi-asserted-by":"publisher","first-page":"401","DOI":"10.1080\/05704928.2021.2016792","volume":"58","author":"SR Pu","year":"2023","unstructured":"Pu SR, Pan Y, Zhang LC, Lv Y (2023) Recent advances in chemiluminescence and cataluminescence for the detection of volatile sulfur compounds. Appl Spectrosc Rev 58(6):401\u2013427. https:\/\/doi.org\/10.1080\/05704928.2021.2016792","journal-title":"Appl Spectrosc Rev"},{"issue":"24","key":"7735_CR18","doi-asserted-by":"publisher","first-page":"3085","DOI":"10.1039\/c9ay00645a","volume":"11","author":"Z Fang","year":"2019","unstructured":"Fang Z, Yue GY, Wang J, Luo F, Guo LH, Qiu B, Lin ZY (2019) Chemiluminescent sensor for hydrogen sulfide in rat brain microdialysis based on target-induced horseradish peroxidase deactivation. Anal Methods 11(24):3085\u20133089. https:\/\/doi.org\/10.1039\/c9ay00645a","journal-title":"Anal Methods"},{"issue":"18","key":"7735_CR19","doi-asserted-by":"publisher","first-page":"4665","DOI":"10.1002\/chem.201900151","volume":"25","author":"LY Zhu","year":"2019","unstructured":"Zhu LY, Wong BJC, Li Y, Xin H, Liu B, Lei JP (2019) Quencher-delocalized emission strategy of AIEgen-based metal-organic framework for profiling of subcellular glutathione. Chem Eur J 25(18):4665\u20134669. https:\/\/doi.org\/10.1002\/chem.201900151","journal-title":"Chem Eur J"},{"issue":"102","key":"7735_CR20","doi-asserted-by":"publisher","first-page":"84134","DOI":"10.1039\/c5ra18499a","volume":"5","author":"SL Jackson","year":"2015","unstructured":"Jackson SL, Rananaware A, Rix C, Bhosale SV, Latham K (2015) Clathrate directed assembly of tetrapyridyl-tetraphenylethylene metal-organic frameworks. RSC Adv 5(102):84134\u201384141. https:\/\/doi.org\/10.1039\/c5ra18499a","journal-title":"RSC Adv"},{"issue":"10","key":"7735_CR21","doi-asserted-by":"publisher","first-page":"1346","DOI":"10.1016\/j.freeradbiomed.2009.09.018","volume":"47","author":"MN Hughes","year":"2009","unstructured":"Hughes MN, Centelles MN, Moore KP (2009) Making and working with hydrogen sulfide the chemistry and generation of hydrogen sulfide in vitro and its measurement in vivo: a review. Free Radic Biol Med 47(10):1346\u20131353. https:\/\/doi.org\/10.1016\/j.freeradbiomed.2009.09.018","journal-title":"Free Radic Biol Med"},{"issue":"26","key":"7735_CR22","doi-asserted-by":"publisher","first-page":"9158","DOI":"10.1021\/acs.analchem.1c01011","volume":"93","author":"ZZ Li","year":"2021","unstructured":"Li ZZ, Li YZ, Zhan LP, Meng LW, Huang X, Wang T, Li YF, Nie ZX (2021) Point-of-care test paper for exhaled breath aldehyde analysis via mass spectrometry. Anal Chem 93(26):9158\u20139165. https:\/\/doi.org\/10.1021\/acs.analchem.1c01011","journal-title":"Anal Chem"},{"issue":"11","key":"7735_CR23","doi-asserted-by":"publisher","first-page":"8688","DOI":"10.1021\/am501446g","volume":"6","author":"I Obraztsov","year":"2014","unstructured":"Obraztsov I, Noworyta K, Hart A, Gobeze HB, Chandra BK, Kutner W, D\u2019Souza F (2014) Langmuir-blodgett films of self-assembled (alkylether-derivatized Zn phthalocyanine)-(C60 imidazole adduct) dyad with controlled intermolecular distance for photoelectrochemical studies. ACS Appl Mater Interfaces 6(11):8688\u20138701. https:\/\/doi.org\/10.1021\/am501446g","journal-title":"ACS Appl Mater Interfaces"},{"key":"7735_CR24","doi-asserted-by":"publisher","first-page":"104246","DOI":"10.1016\/j.microc.2019.104246","volume":"151","author":"JL Wang","year":"2019","unstructured":"Wang JL, Wu ZL, Chen SH, Yuan R, Dong L (2019) A novel multifunctional fluorescent sensor based on N\/S Co-doped carbon dots for detecting Cr (VI) and toluene. Microchem J 151:104246. https:\/\/doi.org\/10.1016\/j.microc.2019.104246","journal-title":"Microchem J"},{"issue":"6","key":"7735_CR25","doi-asserted-by":"publisher","first-page":"5633","DOI":"10.1021\/acsami.7b17755","volume":"10","author":"XY Zhao","year":"2018","unstructured":"Zhao XY, Song XY, Li Y, Chang Z, Chen L (2018) Targeted construction of light-harvesting metal-organic frameworks featuring efficient host-guest energy transfer. ACS Appl Mater Interfaces 10(6):5633\u20135640. https:\/\/doi.org\/10.1021\/acsami.7b17755","journal-title":"ACS Appl Mater Interfaces"},{"key":"7735_CR26","doi-asserted-by":"publisher","first-page":"1446307","DOI":"10.3389\/fmats.2024.1446307","volume":"14","author":"YR Pei","year":"2024","unstructured":"Pei YR, Liu LX, Cao XF, Zhou J, Liu CY (2024) Advances in the study of AIE polymers. Front Mater 14:1446307. https:\/\/doi.org\/10.3389\/fmats.2024.1446307","journal-title":"Front Mater"},{"issue":"1","key":"7735_CR27","doi-asserted-by":"publisher","first-page":"114","DOI":"10.1002\/chem.201904054","volume":"26","author":"L Delafresnaye","year":"2020","unstructured":"Delafresnaye L, Bloesser FR, Kockler KB, Schmitt CW, Irshadeen IM, Barner-Kowollik C (2020) All eyes on visible-light peroxyoxalate chemiluminescence read-out systems. Chem-Eur 26(1):114\u2013127. https:\/\/doi.org\/10.1002\/chem.201904054","journal-title":"Chem-Eur"},{"issue":"4","key":"7735_CR28","doi-asserted-by":"publisher","first-page":"e59658","DOI":"10.1371\/journal.pone.0059658","volume":"8","author":"F Morisco","year":"2013","unstructured":"Morisco F, Aprea E, Lembo V, Fogliano V, Vitaglione P, Mazzone G, Cappellin L, Gasperi F, Masone S, Palma GDD, Marmo R, Caporaso N, Biasioli F (2013) Rapid \u201cbreath-print\u201d of liver cirrhosis by proton transfer reaction time-of-flight mass spectrometry. A pilot study. PLOS One 8(4):e59658. https:\/\/doi.org\/10.1371\/journal.pone.0059658","journal-title":"PLOS One"},{"issue":"6","key":"7735_CR29","doi-asserted-by":"publisher","first-page":"E614","DOI":"10.1002\/ijc.29166","volume":"136","author":"H Amal","year":"2015","unstructured":"Amal H, Shi DY, Ionescu R, Zhang W, Hua QL, Pan YY, Tao L, Liu H, Haick H (2015) Assessment of ovarian cancer conditions from exhaled breath. Int J Cancer 136(6):E614\u2013E622. https:\/\/doi.org\/10.1002\/ijc.29166","journal-title":"Int J Cancer"},{"issue":"3","key":"7735_CR30","doi-asserted-by":"publisher","first-page":"391","DOI":"10.1002\/bmc.1460","volume":"25","author":"A Ulanowska","year":"2011","unstructured":"Ulanowska A, Kowalkowski T, Hrynkiewicz K, Jackowski M, Buszewski B (2011) Determination of volatile organic compounds in human breath for Helicobacter pylori detection by SPME-GC\/MS. Biomed Chromatogr 25(3):391\u2013397. https:\/\/doi.org\/10.1002\/bmc.1460","journal-title":"Biomed Chromatogr"},{"key":"7735_CR31","doi-asserted-by":"publisher","first-page":"113193","DOI":"10.1016\/j.bios.2021.113193","volume":"182","author":"A Vasilescu","year":"2021","unstructured":"Vasilescu A, Hrinczenko B, Swain GM, Peteu SF (2021) Exhaled breath biomarker sensing. Biosens Bioelectron 182:113193. https:\/\/doi.org\/10.1016\/j.bios.2021.113193","journal-title":"Biosens Bioelectron"}],"container-title":["Microchimica Acta"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00604-025-07735-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00604-025-07735-4","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00604-025-07735-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,22]],"date-time":"2026-01-22T16:57:00Z","timestamp":1769101020000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00604-025-07735-4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12,3]]},"references-count":31,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026,1]]}},"alternative-id":["7735"],"URL":"https:\/\/doi.org\/10.1007\/s00604-025-07735-4","relation":{"has-preprint":[{"id-type":"doi","id":"10.21203\/rs.3.rs-7195328\/v1","asserted-by":"object"}]},"ISSN":["0026-3672","1436-5073"],"issn-type":[{"value":"0026-3672","type":"print"},{"value":"1436-5073","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,12,3]]},"assertion":[{"value":"23 July 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"19 November 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"3 December 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"This study received approval from the Committee on Ethics at Shaanxi Normal University, and all volunteers provided informed consent prior to their participation.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"The authors declare no competing interests.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"4"}}