{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T15:26:12Z","timestamp":1786980372805,"version":"build-2736575974"},"reference-count":66,"publisher":"Springer Science and Business Media LLC","issue":"12","license":[{"start":{"date-parts":[[2025,11,29]],"date-time":"2025-11-29T00:00:00Z","timestamp":1764374400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2025,11,29]],"date-time":"2025-11-29T00:00:00Z","timestamp":1764374400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"name":"the Natural Science Foundation of Fujian Province","award":["2021J05194"],"award-info":[{"award-number":["2021J05194"]}]},{"name":"the Natural Science Foundation of Fujian Province","award":["2025J01971"],"award-info":[{"award-number":["2025J01971"]}]},{"name":"the Open Project Program of Key Laboratory for Analytical Science of Food Safety and Biology, Ministry of Education","award":["FS2503"],"award-info":[{"award-number":["FS2503"]}]},{"name":"the Education-Science Research Project for Young and Middle-aged Teachers of Fujian Province","award":["JAT210282"],"award-info":[{"award-number":["JAT210282"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Microchim Acta"],"published-print":{"date-parts":[[2025,12]]},"DOI":"10.1007\/s00604-025-07738-1","type":"journal-article","created":{"date-parts":[[2025,11,29]],"date-time":"2025-11-29T21:16:15Z","timestamp":1764450975000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Flower-like Fe3S4 nanozymes with peroxidase-like activity for sensitive colorimetric immunodetection of carcinoembryonic antigen"],"prefix":"10.1007","volume":"192","author":[{"given":"Xiaoyan","family":"Deng","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xuwei","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rong","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuwei","family":"Pan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Youxiu","family":"Lin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dianping","family":"Tang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenqiang","family":"Lai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,11,29]]},"reference":[{"key":"7738_CR1","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1186\/s13045-025-01688-0","volume":"18","author":"H Jia","year":"2025","unstructured":"Jia H, Chen X, Zhang L, Chen M (2025) Cancer associated fibroblasts in cancer development and therapy. J Hematol Onvol 18:36","journal-title":"J Hematol Onvol"},{"key":"7738_CR2","doi-asserted-by":"crossref","first-page":"18192","DOI":"10.1021\/acsnano.1c07075","volume":"15","author":"J Penders","year":"2021","unstructured":"Penders J, Nagelkerke A, Cunnane EM, Pedersen SV, Pence IJ, Coombes RC, Stevens MM (2021) Single particle automated raman trapping analysis of breast cancer cell-derived extracellular vesicles as cancer biomarkers. ACS Nano 15:18192\u201318205","journal-title":"ACS Nano"},{"key":"7738_CR3","doi-asserted-by":"crossref","first-page":"2479","DOI":"10.1021\/acs.analchem.4c06223","volume":"97","author":"J Lv","year":"2025","unstructured":"Lv J, Chen S, Xu W, Zhang X, Wang M, Xu J, Zhu Z, Hu Q, Niu L (2025) Lectin-mediated labeling of alkaline phosphatase for enzymatic silver deposition-based electrochemical detection of glycoprotein tumor markers. Anal Chem 97:2479\u20132485","journal-title":"Anal Chem"},{"key":"7738_CR4","volume":"469","author":"J Shi","year":"2022","unstructured":"Shi J, Chen Z, Zhao C, Shen M, Li H, Zhang S, Zhang Z (2022) Photoelectrochemical biosensing platforms for tumor marker detection. Coord Chem Rev 469:214675","journal-title":"Coord Chem Rev"},{"key":"7738_CR5","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1007\/s41664-023-00255-1","volume":"7","author":"Y Xia","year":"2023","unstructured":"Xia Y, Che H, Liu R, Shi F, Ren C, Li J, Zhao J, Chen X, Yang Z (2023) Mesoporous SiO2 sphere-based electrochemical impedance immunosensor for ultrasensitive detection of bovine interferon-\u03b3. J Anal Test 7:295\u2013303","journal-title":"J Anal Test"},{"key":"7738_CR6","volume":"466","author":"J Xu","year":"2023","unstructured":"Xu J, Liu Y, Huang K, Wang R, Li J (2023) Cascade amplification strategy based on ultra-thin graphdiyne and CRISPR\/Cas for real-time detection of tumor biomarker. Chem Eng J 466:143230","journal-title":"Chem Eng J"},{"key":"7738_CR7","doi-asserted-by":"crossref","DOI":"10.1016\/j.trac.2020.116064","volume":"132","author":"KG Stevens","year":"2020","unstructured":"Stevens G, Pukala L (2020) Conjugating immunoassays to mass spectrometry: solutions to contemporary challenges in clinical diagnostics. TrAC Trends Anal Chem 132:116064","journal-title":"TrAC Trends Anal Chem"},{"key":"7738_CR8","volume":"219","author":"R Shu","year":"2023","unstructured":"Shu R, Liang Y, Liu S, Dou L, Bu T, Wang S, Lan X, Zhang D, Sun J, Zhu M, Wang J (2023) From food waste to food supervision\u201d-cuttlefish ink natural nanoparticles-driven dual-mode lateral flow immunoassay for advancing point-of-care tests. Biosens Bioelectron 219:114807","journal-title":"Biosens Bioelectron"},{"key":"7738_CR9","volume":"143","author":"T Zhou","year":"2021","unstructured":"Zhou T, Li H, Shang M, Sun D, Liu C, Che G (2021) Recent analytical methodologies and analytical trends for riboflavin (vitamin B2) analysis in food, biological and pharmaceutical samples. TrAC Trends Anal Chem 143:116412","journal-title":"TrAC Trends Anal Chem"},{"key":"7738_CR10","doi-asserted-by":"crossref","first-page":"2189","DOI":"10.1021\/acs.analchem.1c04709","volume":"94","author":"F Du","year":"2022","unstructured":"Du F, Dong Z, Guan Y, Zeid AM, Ma D, Feng J, Yang D, Xu G (2022) Single-electrode electrochemical system for the visual and high-throughput electrochemiluminescence immunoassay. Anal Chem 94:2189\u20132194","journal-title":"Anal Chem"},{"key":"7738_CR11","doi-asserted-by":"crossref","first-page":"2854","DOI":"10.1021\/acs.nanolett.3c00184","volume":"23","author":"Y Zeng","year":"2023","unstructured":"Zeng Y, Mu Z, Nie B, Qu X, Zhang Y, Li C, Sun L, Li G (2023) Engineered Escherichia coli as a controlled-release biocarrier for electrochemical immunoassay. Nano Lett 23:2854\u20132861","journal-title":"Nano Lett"},{"key":"7738_CR12","doi-asserted-by":"crossref","first-page":"3505","DOI":"10.1021\/acs.analchem.7b05325","volume":"90","author":"C Chen","year":"2018","unstructured":"Chen C, Zhao J, Lu Y, Sun J, Yang X (2018) Fluorescence immunoassay based on the phosphate-triggered fluorescence turn-on detection of alkaline phosphatase. Anal Chem 90:3505\u20133511","journal-title":"Anal Chem"},{"key":"7738_CR13","doi-asserted-by":"crossref","first-page":"12070","DOI":"10.1021\/acs.analchem.2c01771","volume":"94","author":"Y Xu","year":"2022","unstructured":"Xu Y, Gao X, Wang D, Jia J, Zhang B, Zou G (2022) Surface defect-involved and single-color electrochemiluminescence of gold nanoclusters for immunoassay. Anal Chem 94:12070\u201312077","journal-title":"Anal Chem"},{"key":"7738_CR14","doi-asserted-by":"crossref","first-page":"11099","DOI":"10.1021\/acs.analchem.8b03538","volume":"90","author":"R Ren","year":"2018","unstructured":"Ren R, Cai G, Yu Z, Zeng Y, Tang D (2018) Metal-polydopamine framework: an innovative signal-generation tag for colorimetric immunoassay. Anal Chem 90:11099\u201311105","journal-title":"Anal Chem"},{"key":"7738_CR15","doi-asserted-by":"crossref","first-page":"4639","DOI":"10.1021\/acs.analchem.0c00224","volume":"92","author":"C Chen","year":"2020","unstructured":"Chen C, Zhao D, Wang B, Ni P, Jiang Y, Zhang C, Yang F, Lu Y, Sun J (2020) Alkaline phosphatase-triggered in situ formation of silicon-containing nanoparticles for a fluorometric and colorimetric dual-channel immunoassay. Anal Chem 92:4639\u20134646","journal-title":"Anal Chem"},{"key":"7738_CR16","doi-asserted-by":"crossref","DOI":"10.1016\/j.ccr.2021.214061","volume":"446","author":"R Umapathi","year":"2021","unstructured":"Umapathi R, Sonwal S, Lee M, Rani G, Lee E, Jeon T, Kang S, Oh M, Huh Y (2021) Colorimetric based on-site sensing strategies for the rapid detection of pesticides in agricultural foods: new horizons, perspectives, and challenges. Coordin Chem Rev 446:214061","journal-title":"Coordin Chem Rev"},{"key":"7738_CR17","doi-asserted-by":"crossref","DOI":"10.1016\/j.aca.2022.340634","volume":"1238","author":"Y Shan","year":"2023","unstructured":"Shan Y, Wang B, Huang H, Yan K, Li W, Wang S, Liu F (2023) Portable high-throughput multimodal immunoassay platform for rapid on-site COVID-19 diagnostics. Anal Chim Acta 1238:340634","journal-title":"Anal Chim Acta"},{"key":"7738_CR18","doi-asserted-by":"crossref","first-page":"575","DOI":"10.1007\/s00604-024-06657-x","volume":"191","author":"M Liu","year":"2024","unstructured":"Liu M, Wang Y, Xiao J, Liu Y, Ren Y, Gao X (2024) Colorimetric immunoassay of Furazolidone metabolites based on iron-copper bimetallic organic framework nanoenzyme. Microchim Acta 191:575","journal-title":"Microchim Acta"},{"key":"7738_CR19","volume":"514","author":"J Cao","year":"2025","unstructured":"Cao J, Li T, Liao X, Zhang J, Yang X, Yan H, Sun B, Li Y, Huang J, Wang Y, Hu X, Wang L (2025) Ultrasensitive nanoenzymes-based lateral flow immunoassay platform for accurate detection of folic acid in human serum. Chem Eng J 514:163221","journal-title":"Chem Eng J"},{"key":"7738_CR20","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1038\/nrc1566","volume":"5","author":"M Ferrari","year":"2005","unstructured":"Ferrari M (2005) Cancer nanotechnology: opportunities and challenges. Nat Rev Cancer 5:161\u2013171","journal-title":"Nat Rev Cancer"},{"key":"7738_CR21","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1146\/annurev.bioeng.9.060906.152025","volume":"9","author":"S Nie","year":"2007","unstructured":"Nie S, Xing Y, Kim G, Simons J (2007) Nanotechnology applications in cancer. Annu Rev Biomed Eng 9:257\u2013288","journal-title":"Annu Rev Biomed Eng"},{"key":"7738_CR22","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1186\/s12951-018-0392-8","volume":"16","author":"J Patra","year":"2018","unstructured":"Patra J, Das G, Fraceto L, Campos E, Rodriguez-Torres M, Acosta-Torres L, Diaz-Torres L, Grillo R, Swamy M, Sharma S, Habtemariam S, Shin H (2018) Nano based drug delivery systems: recent developments and future prospects. J Nanobiotechnol 16:71","journal-title":"J Nanobiotechnol"},{"key":"7738_CR23","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1021\/nn900002m","volume":"3","author":"O Farokhzad","year":"2009","unstructured":"Farokhzad O, Langer R (2009) Impact of nanotechnology on drug delivery. ACS Nano 3:16\u201320","journal-title":"ACS Nano"},{"key":"7738_CR24","volume":"322","author":"S Jangi","year":"2024","unstructured":"Jangi S (2024) Developing a label-free full-range highly selective pH nanobiosensor using a novel high quantum yield pH-responsive activated-protein-protected gold nanocluster prepared by a novel ultrasonication-protein-assisted procedure. Spectrochim Acta A Mol Biomol Spectrosc 322:124829","journal-title":"Spectrochim Acta A Mol Biomol Spectrosc"},{"key":"7738_CR25","doi-asserted-by":"crossref","first-page":"124977","DOI":"10.1016\/j.talanta.2023.124977","volume":"266","author":"Z Dehghani","year":"2024","unstructured":"Dehghani Z, Akhond M, Jangi S, Absalan G (2024) Highly sensitive enantioselective spectrofluorimetric determination of R-\/S-mandelic acid using l-tryptophan-modified amino-functional silica-coated N-doped carbon dots as novel high-throughput chiral nanoprobes. Talanta 266:124977","journal-title":"Talanta"},{"key":"7738_CR26","doi-asserted-by":"crossref","first-page":"6505","DOI":"10.1007\/s11696-023-02954-6","volume":"77","author":"S Jangi","year":"2023","unstructured":"Jangi S, Gholamhosseinzadeh E (2023) Developing an ultra-reproducible and ultrasensitive label-free nanoassay for L-methionine quantification in biological samples toward application in homocystinuria diagnosis. Chem Pap 77:6505\u20136517","journal-title":"Chem Pap"},{"key":"7738_CR27","volume":"1320","author":"S Jangi","year":"2024","unstructured":"Jangi S (2024) Developing a novel ultraselective and ultrasensitive label-free direct spectrofluorimetric nanobiosensor for direct highly fast field detection of explosive triacetone triperoxide. Anal Chim Acta 1320:343016","journal-title":"Anal Chim Acta"},{"key":"7738_CR28","doi-asserted-by":"crossref","first-page":"4963","DOI":"10.1007\/s11696-023-02834-z","volume":"77","author":"S Jangi","year":"2023","unstructured":"Jangi S (2023) Low-temperature destructive hydrodechlorination of long-chain chlorinated paraffins to diesel and gasoline range hydrocarbons over a novel low-cost reusable ZSM-5@Al-MCM nanocatalyst: a new approach toward reuse instead of common mineralization. Chem Pap 77:4963\u20134977","journal-title":"Chem Pap"},{"key":"7738_CR29","doi-asserted-by":"crossref","first-page":"134139","DOI":"10.1016\/j.fuel.2024.134139","volume":"385","author":"Z Dehghani","year":"2025","unstructured":"Dehghani Z, Jangi S (2025) Novel nanophotocatalytic double Z-scheme CdS\/Ag-AgBr\/Au-loaded amino-defective-UiO-66(Ce) for rapid high throughput reusable photocatalytic methanol synthesis from CO2. Fuel 385:134139","journal-title":"Fuel"},{"key":"7738_CR30","doi-asserted-by":"crossref","first-page":"316","DOI":"10.1016\/j.colsurfb.2018.01.050","volume":"164","author":"W Zhao","year":"2018","unstructured":"Zhao W, Liu Q, Zhang X, Su B, Zhao C (2018) Rationally designed magnetic nanoparticles as anticoagulants for blood purification. Colloid Surf B 164:316\u2013323","journal-title":"Colloid Surf B"},{"key":"7738_CR31","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1016\/j.procbio.2021.03.027","volume":"105","author":"S Jangi","year":"2021","unstructured":"Jangi S, Akhond M (2021) High throughput urease immobilization onto a new metal-organic framework called nanosized electroactive quasi-coral-340 (NEQC-340) for water treatment and safe blood cleaning. Process Biochem 105:79\u201390","journal-title":"Process Biochem"},{"key":"7738_CR32","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1007\/s00604-020-04409-1","volume":"187","author":"S Jangi","year":"2020","unstructured":"Jangi S, Akhond M, Absalan G (2020) A field-applicable colorimetric assay for notorious explosive triacetone triperoxide through nanozyme-catalyzed irreversible oxidation of 3, 3\u2032-diaminobenzidine. Microchim Acta 187:431","journal-title":"Microchim Acta"},{"key":"7738_CR33","doi-asserted-by":"crossref","first-page":"123546","DOI":"10.1016\/j.talanta.2022.123546","volume":"247","author":"W Lai","year":"2022","unstructured":"Lai W, Guo J, Wang Y, Lin Y, Ye S, Zhuang J, Tang D (2022) Enzyme-controllable just-in-time production system of copper hexacyanoferrate nanoparticles with oxidase-mimicking activity for highly sensitive colorimetric immunoassay. Talanta 247:123546","journal-title":"Talanta"},{"key":"7738_CR34","doi-asserted-by":"crossref","first-page":"3234","DOI":"10.1039\/D2AN00864E","volume":"147","author":"A Amalraj","year":"2022","unstructured":"Amalraj A, Narayanana M, Perumal P (2022) Highly efficient peroxidase-like activity of a metal-oxide-incorporated CeO2-MIL(Fe) metal\u2013organic framework and its application in the colorimetric detection of melamine and mercury ions via induced hydrogen and covalent bonds. Analyst 147:3234\u20133247","journal-title":"Analyst"},{"key":"7738_CR35","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.procbio.2024.12.025","volume":"150","author":"S Jangi","year":"2025","unstructured":"Jangi S, Dehghani Z (2025) A novel dual-function biomimetic approach for high throughput organic dye biodegradation and hydrogen peroxide sensing using a nanosized artificial peroxidase with ultra-improved substrate affinity and superb catalytic efficiency. Process Biochem 150:1\u201320","journal-title":"Process Biochem"},{"key":"7738_CR36","doi-asserted-by":"crossref","first-page":"645","DOI":"10.1016\/j.bios.2015.12.035","volume":"89","author":"W Lai","year":"2017","unstructured":"Lai W, Wei Q, Xu M, Zhuang J, Tang D (2017) Enzyme-controlled dissolution of MnO2 nanoflakes with enzyme cascade amplification for colorimetric immunoassay. Biosens Bioelectron 89:645\u2013651","journal-title":"Biosens Bioelectron"},{"key":"7738_CR37","volume":"429","author":"X Zhang","year":"2021","unstructured":"Zhang X, Lin S, Liu S, Tan X, Dai Y, Xia F (2021) Advances in organometallic\/organic nanozymes and their applications. Coord Chem Rev 429:213652","journal-title":"Coord Chem Rev"},{"key":"7738_CR38","doi-asserted-by":"crossref","DOI":"10.1016\/j.saa.2022.121782","volume":"284","author":"S Huang","year":"2023","unstructured":"Huang S, Lai W, Liu B, Xu M, Zhuang J, Tang D, Lin Y (2023) Colorimetric and photothermal dual-mode immunoassay of aflatoxin B1 based on peroxidase-like activity of Pt supported on nitrogen-doped carbon. Spectrochim Acta A Mol Biomol Spectrosc 284:121782","journal-title":"Spectrochim Acta A Mol Biomol Spectrosc"},{"key":"7738_CR39","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1007\/s00604-020-4172-4","volume":"187","author":"H Yang","year":"2020","unstructured":"Yang H, Xu W, Liang X, Yang Y, Zhou Y (2020) Carbon nanotubes in electrochemical, colorimetric, and fluorimetric immunosensors and immunoassays: a review. Microchim Acta 187:206","journal-title":"Microchim Acta"},{"key":"7738_CR40","doi-asserted-by":"crossref","first-page":"5157","DOI":"10.1039\/D3AN01242E","volume":"148","author":"R Jesuraj","year":"2023","unstructured":"Jesuraj R, Amalraj A, Vaidyanathanb V, Perumal P (2023) Exceptional peroxidase-like activity of an iron and copper based organic framework nanosheet for consecutive colorimetric biosensing of glucose and kanamycin in real food samples. Analyst 148:5157\u20135171","journal-title":"Analyst"},{"key":"7738_CR41","doi-asserted-by":"crossref","first-page":"12353","DOI":"10.1021\/acs.analchem.1c02115","volume":"93","author":"Y Chen","year":"2021","unstructured":"Chen Y, Jiao L, Yan H, Xu W, Wu Y, Zheng L, Gu W, Zhu C (2021) Fe-N-C single-atom catalyst coupling with Pt clusters boosts peroxidase-like activity for cascade-amplified colorimetric immunoassay. Anal Chem 93:12353\u201312359","journal-title":"Anal Chem"},{"key":"7738_CR42","doi-asserted-by":"crossref","first-page":"25113","DOI":"10.1021\/acsami.8b07225","volume":"10","author":"C Wang","year":"2018","unstructured":"Wang C, Gao J, Tan H (2018) Integrated antibody with catalytic metal-organic framework for colorimetric immunoassay. ACS Appl Mater Interfaces 10:25113\u201325120","journal-title":"ACS Appl Mater Interfaces"},{"key":"7738_CR43","volume":"1354","author":"X Li","year":"2025","unstructured":"Li X, Lin H, Chen X, Luo F, Zhang R, Deng X, Lin Y, Tang D, Lai W (2025) Instant synthesis of bimetallic CuCo PBA nanozyme for efficient colorimetric immunoassay of carcinoembryonic antigen. Anal Chim Acta 1354:343981","journal-title":"Anal Chim Acta"},{"key":"7738_CR44","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1016\/j.jallcom.2009.08.127","volume":"488","author":"Z Zhang","year":"2009","unstructured":"Zhang Z, Chen X (2009) Magnetic greigite (Fe3S4) nanomaterials: shape-controlled solvothermal synthesis and their calcination conversion into hematite (\u03b1-Fe2O3) nanomaterials. J Alloy Compd 488:339\u2013345","journal-title":"J Alloy Compd"},{"key":"7738_CR45","doi-asserted-by":"crossref","first-page":"6688","DOI":"10.1021\/ac400517e","volume":"85","author":"D Yang","year":"2013","unstructured":"Yang D, Ma J, Zhang Q, Li N, Yang J, Raju P, Peng M, Luo Y, Hui W, Chen C, Cui Y (2013) Polyelectrolyte-coated gold magnetic nanoparticles for immunoassay development: toward point of care diagnostics for syphilis screening. Anal Chem 85:6688\u20136695","journal-title":"Anal Chem"},{"key":"7738_CR46","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1140\/epje\/i2006-10051-y","volume":"21","author":"M R\u0103cuciu","year":"2006","unstructured":"R\u0103cuciu M, Creang\u0103 D, Airinei A (2006) Citric-acid-coated magnetite nanoparticles for biological applications. Eur Phys J E 21:117\u2013121","journal-title":"Eur Phys J E"},{"key":"7738_CR47","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/j.polymertesting.2007.08.007","volume":"27","author":"T Kijchavengkul","year":"2008","unstructured":"Kijchavengkul T, Auras R, Rubino M (2008) Measuring gel content of aromatic polyesters using FTIR spectrophotometry and DSC. Polym Test 27:55\u201360","journal-title":"Polym Test"},{"key":"7738_CR48","volume":"850","author":"Z Hao","year":"2019","unstructured":"Hao Z, Wei P, Kang H, Yang Y, Li J, Chen X, Guo D, Liu L (2019) Three-dimensional Fe3S4@NiS hollow nanospheres as efficient electrocatalysts for oxygen evolution reaction. J Electroanal Chem 850:113436","journal-title":"J Electroanal Chem"},{"key":"7738_CR49","doi-asserted-by":"crossref","first-page":"855","DOI":"10.3389\/fchem.2019.00855","volume":"7","author":"H Wang","year":"2019","unstructured":"Wang H, Qiu X, Wang W, Jiang L, Liu H (2019) Iron sulfide nanoparticles embedded into a nitrogen and sulfur Co-doped carbon sphere as a highly active oxygen reduction electrocatalyst. Front Chem 7:855","journal-title":"Front Chem"},{"key":"7738_CR50","doi-asserted-by":"crossref","first-page":"20093","DOI":"10.1039\/C8TA07849A","volume":"6","author":"H Jin","year":"2018","unstructured":"Jin H, Zhou H, Li W, Wang Z, Yang J, Xiong Y, He D, Chem L, Mu S (2018) In situ derived Fe\/N\/S-codoped carbon nanotubes from ZIF-8 crystals as efficient electrocatalysts for the oxygen reduction reaction and zinc-air batteries. J Mater Chem A 6:20093\u201320099","journal-title":"J Mater Chem A"},{"key":"7738_CR51","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1007\/s00604-012-0839-9","volume":"178","author":"W Lai","year":"2012","unstructured":"Lai W, Zhuang J, Tang J, Chen G, Tang D (2012) One-step electrochemical immunosensing for simultaneous detection of two biomarkers using thionine and ferrocene as distinguishable signal tags. Microchim Acta 178:357\u2013365","journal-title":"Microchim Acta"},{"key":"7738_CR52","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1016\/j.bios.2016.01.088","volume":"80","author":"W Lai","year":"2016","unstructured":"Lai W, Wei Q, Zhuang J, Lu M, Tang D (2016) Fenton reaction-based colorimetric immunoassay for sensitive detection of brevetoxin B. Biosens Bioelectron 80:249\u2013256","journal-title":"Biosens Bioelectron"},{"key":"7738_CR53","doi-asserted-by":"crossref","first-page":"16131","DOI":"10.1021\/acssuschemeng.9b03043","volume":"7","author":"P Borthakur","year":"2019","unstructured":"Borthakur P, Das MR, Szunerits S, Boukherroub R (2019) CuS decorated functionalized reduced graphene oxide: a dual responsive nanozyme for selective detection and photoreduction of Cr(VI) in an aqueous medium. ACS Sustainable Chem Eng 7:16131\u201316143","journal-title":"ACS Sustainable Chem Eng"},{"key":"7738_CR54","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1038\/nnano.2007.260","volume":"2","author":"L Gao","year":"2007","unstructured":"Gao L, Zhuang J, Nie L, Zhang J, Zhang Y, Gu N, Wang T, Feng J, Yang D, Perrett S, Yan X (2007) Intrinsic peroxidase-like activity of ferromagnetic nanoparticles. Nat Nanotechnol 2:577\u2013583","journal-title":"Nat Nanotechnol"},{"key":"7738_CR55","volume":"253","author":"Y Qi","year":"2022","unstructured":"Qi Y, Sun Y, Song D, Wang Y, Xiu F (2022) PVC dechlorination residues as new peroxidase-mimicking nanozyme and chemiluminescence sensing probe with high activity for glucose and ascorbic acid detection. Talanta 253:124039","journal-title":"Talanta"},{"key":"7738_CR56","doi-asserted-by":"crossref","first-page":"3125","DOI":"10.1039\/D0OB00122H","volume":"18","author":"J Li","year":"2020","unstructured":"Li J, Jia W, Ma G, Zhang X, An S, Wang T, Shi S (2020) Construction of pH sensitive smart glutathione peroxidase (GPx) mimics based on pH responsive pseudorotaxanes. Org Biomol Chem 18:3125\u20133134","journal-title":"Org Biomol Chem"},{"key":"7738_CR57","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/j.aca.2012.11.056","volume":"762","author":"L Hu","year":"2013","unstructured":"Hu L, Yuan Y, Zhang L, Zhao J, Majeed S, Xu G (2013) Copper nanoclusters as peroxidase mimetics and their applications to H2O2 and glucose detection. Anal Chim Acta 762:83\u201386","journal-title":"Anal Chim Acta"},{"key":"7738_CR58","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/j.talanta.2015.03.055","volume":"141","author":"K Zhao","year":"2015","unstructured":"Zhao K, Gu W, Zheng S, Zhang C, Xian Y (2015) SDS-MoS2 nanoparticles as highly-efficient peroxidase mimetics for colorimetric detection of H2O2 and glucose. Talanta 141:47\u201352","journal-title":"Talanta"},{"key":"7738_CR59","doi-asserted-by":"crossref","first-page":"4657","DOI":"10.1039\/C6TB01233G","volume":"4","author":"R Cai","year":"2016","unstructured":"Cai R, Yang D, Chen X, Huang Y, Lyu Y, He J, Shi M, Teng I, Wan S, Hou W, Tan W (2016) Three dimensional multipod superstructures based on Cu(OH)2 as a highly efficient nanozyme. J Mater Chem B 4:4657\u20135661","journal-title":"J Mater Chem B"},{"key":"7738_CR60","volume":"474","author":"A Wu","year":"2023","unstructured":"Wu A, Han M, Ding H, Rao H, Lu Z, Sun M, Wang Y, Chen Y, Zhang Y, Wang X, Chen D (2023) Fe3S4 nanozyme inhibits tumor growth by synergistic effects of ferroptosis and apoptosis. Chem Eng J 474:145920","journal-title":"Chem Eng J"},{"key":"7738_CR61","doi-asserted-by":"crossref","first-page":"7372","DOI":"10.1039\/D4AY01480D","volume":"16","author":"Y Zhang","year":"2024","unstructured":"Zhang Y, Xu J, Shen J, Zhang B, Xue T, Lv X, Zhang X, Zhu G (2024) A dual-mode homogeneous electrochemical-colorimetric biosensing sensor for carcinoembryonic antigen detection based on a microfluidic paper-based analysis device. Anal Methods 16:7372\u20137380","journal-title":"Anal Methods"},{"key":"7738_CR62","doi-asserted-by":"crossref","first-page":"10994","DOI":"10.1039\/C4RA14833A","volume":"5","author":"C Luo","year":"2015","unstructured":"Luo C, Wen W, Lin F, Zhang X, Gu H, Wang S (2015) Simplified aptamer-based colorimetric method using unmodified gold nanoparticles for the detection of carcinoma embryonic antigen. RSC Adv 5:10994","journal-title":"RSC Adv"},{"key":"7738_CR63","doi-asserted-by":"crossref","first-page":"6931","DOI":"10.1021\/acsami.6b15750","volume":"9","author":"L Xiao","year":"2017","unstructured":"Xiao L, Zhu A, Xu Q, Chen Y, Xu J, Weng J (2017) Colorimetric biosensor for detection of cancer biomarker by Au nanoparticle-decorated Bi2Se3 nanosheets. ACS Appl Mater Interfaces 9:6931\u20136940","journal-title":"ACS Appl Mater Interfaces"},{"key":"7738_CR64","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1016\/j.aca.2017.01.030","volume":"963","author":"B Li","year":"2017","unstructured":"Li B, Lai G, Zhang H, Hu S, Yu A (2017) Copper chromogenic reaction based colorimetric immunoassay for rapid and sensitive detection of a tumor biomarker. Anal Chim Acta 963:106","journal-title":"Anal Chim Acta"},{"key":"7738_CR65","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1016\/j.talanta.2017.07.039","volume":"175","author":"X Wang","year":"2017","unstructured":"Wang X, Zhang B, Li J, Chang H, Wei W (2017) A simple and fast chromogenic reaction based on Ag3PO4\/Ag nanocomposite for tumor marker detection. Talanta 175:229","journal-title":"Talanta"},{"key":"7738_CR66","doi-asserted-by":"crossref","first-page":"43031","DOI":"10.1021\/acsami.9b18472","volume":"11","author":"S Wu","year":"2019","unstructured":"Wu S, Tan H, Wang C, Wang J, Sheng S (2019) A colorimetric immunoassay based on coordination polymer composite for the detection of carcinoembryonic antigen. ACS Appl Mater Interfaces 11:43031\u201343038","journal-title":"ACS Appl Mater Interfaces"}],"container-title":["Microchimica Acta"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00604-025-07738-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00604-025-07738-1\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00604-025-07738-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,15]],"date-time":"2025-12-15T18:11:42Z","timestamp":1765822302000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00604-025-07738-1"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,11,29]]},"references-count":66,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2025,12]]}},"alternative-id":["7738"],"URL":"https:\/\/doi.org\/10.1007\/s00604-025-07738-1","relation":{},"ISSN":["0026-3672","1436-5073"],"issn-type":[{"value":"0026-3672","type":"print"},{"value":"1436-5073","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,11,29]]},"assertion":[{"value":"13 September 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"20 November 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"29 November 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"866"}}