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Edayathangudy GS Pillay College of Pharmacy, Nagapattinam, Tamil Nadu"},{"key":"7839_CR52","doi-asserted-by":"publisher","first-page":"156","DOI":"10.1002\/bmc.1640","volume":"26","author":"T Boer","year":"2012","unstructured":"Boer T, Meulman E, Meijering H, Wieling J, Dogterom P, Lass H (2012) Quantification of asenapine and three metabolites in human plasma using liquid chromatography tandem mass spectrometry with automated solid-phase extraction: application to a phase I clinical trial with asenapine in healthy male subjects. 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All specimens were de-identified, containing no personal or clinical donor information. The plasma was used exclusively for the development and validation of the analytical method. No human participants were recruited, and no direct interaction or intervention occurred. In accordance with the Institutional Research Board guidelines of Assiut University and international ethical standards, including the Declaration of Helsinki, this work is not classified as human subject research. Therefore, ethical approval and informed consent were not required.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Clinical trial number"}},{"value":"The authors declare no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"181"}}