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The study protocol was approved by the Ethics Committee of the First Affiliated Hospital of Ningbo University (Approval No. 2024\u2009\u2013125\u00a0A). Written informed consent was obtained from all participants prior to sample collection.","order":1,"name":"Ethics","label":"Ethics statement","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":2,"name":"Ethics","label":"Competing interests","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"No artificial intelligence (AI) tools were used in the preparation of this manuscript, including the writing, figures, or graphical abstract.","order":3,"name":"Ethics","label":"AI disclosure","group":{"name":"EthicsHeading","label":"Declarations"}}],"article-number":"519"}}