{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T12:02:40Z","timestamp":1756382560329},"reference-count":22,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2010,10,13]],"date-time":"2010-10-13T00:00:00Z","timestamp":1286928000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acta Neurochir"],"published-print":{"date-parts":[[2011,1]]},"DOI":"10.1007\/s00701-010-0827-y","type":"journal-article","created":{"date-parts":[[2010,10,13]],"date-time":"2010-10-13T09:43:26Z","timestamp":1286963006000},"page":"48-52","source":"Crossref","is-referenced-by-count":7,"title":["Von Hippel\u2013Lindau disease manifesting disseminated leptomeningeal hemangioblastomatosis: surgery or medication?"],"prefix":"10.1007","volume":"153","author":[{"given":"Qiao","family":"zhang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lu","family":"Ma","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wen\u2013yan","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jing","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yan","family":"Ju","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xu\u2013hui","family":"Hui","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2010,10,13]]},"reference":[{"key":"827_CR1","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1111\/jon199774242","volume":"7","author":"R Bakshi","year":"1997","unstructured":"Bakshi R, Mechtler LL, Patel MJ, Lindsay BD, Messinger S, Gibbons KJ (1997) Spinal leptomeningeal hemangioblastomatosis in von Hippel-Lindau disease: magnetic resonance and pathologic findings. J Neuroimaging 7:242\u2013244","journal-title":"J Neuroimaging"},{"key":"827_CR2","first-page":"55","volume":"48","author":"JE Conway","year":"2001","unstructured":"Conway JE, Chou D, Clatterbuck RE, Brem H, Long DM, Rigamonti D (2001) Hemangioblastomas of the central nervous system in von Hippel-Lindau syndrome and sporadic disease. Neurosurgery 48:55\u201363","journal-title":"Neurosurgery"},{"key":"827_CR3","doi-asserted-by":"crossref","first-page":"758","DOI":"10.3174\/ajnr.A1360","volume":"30","author":"NA Courcoutsakis","year":"2009","unstructured":"Courcoutsakis NA, Prassopoulos PK, Patronas NJ (2009) Aggressive leptomeningeal hemangioblastomatosis of the central nervous system in a patient with von Hippel-Lindau disease. AJNR Am J Neuroradiol 30:758\u2013760","journal-title":"AJNR Am J Neuroradiol"},{"key":"827_CR4","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1212\/WNL.41.1.41","volume":"41","author":"MR Filling-Katz","year":"1991","unstructured":"Filling-Katz MR, Choyke PL, Oldfield E, Charnas L, Patronas NJ, Glenn GM, Gorin MB, Morgan JK, Linehan WM, Seizinger BR, Zbar B (1991) Central nervous system involvement in von Hippel\u2013Lindau disease. Neurology 41:41\u201346","journal-title":"Neurology"},{"key":"827_CR5","doi-asserted-by":"crossref","first-page":"1226","DOI":"10.1001\/jama.1992.03480090074030","volume":"267","author":"GM Glenn","year":"1992","unstructured":"Glenn GM, Linehan WM, Hosoe S, Latif F, Yao M, Choyke P, Gorin MB, Chew E, Olfield E, Manolatos C, Orcutt ML, Kwalther MM, Weiss GH, Tory K, Jensson O, Lerman MI, Zber B (1992) Screening for von Hippel-Lindau disease by DNA polymorphism analysis. JAMA 267:1226\u20131231","journal-title":"JAMA"},{"key":"827_CR6","doi-asserted-by":"crossref","first-page":"386","DOI":"10.1210\/jc.2008-1972","volume":"94","author":"C Jimenez","year":"2009","unstructured":"Jimenez C, Cabanillas ME, Santarpia L, Jonasch E, Kyle KL, Lano EA, Matin SF, Nunez RF, Perrier ND, Phan A, Rich TA, Shah B, Williams MD, Waguespack SG (2009) Use of the tyrosine kinase inhibitor sunitinib in a patient with von Hippel-Lindau disease: targeting angiogenic factors in pheochromocytoma and other von Hippel-Lindau disease-related tumors. J Clin Endocrinol Metab 94:386\u2013391","journal-title":"J Clin Endocrinol Metab"},{"key":"827_CR7","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1080\/02688699647186","volume":"10","author":"AM Hande","year":"1996","unstructured":"Hande AM, Nagpal RD (1996) Cerebellar haemangioblastoma with extensive dissemination. Br J Neurosurg 10:507\u2013511","journal-title":"Br J Neurosurg"},{"key":"827_CR8","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1007\/s11060-006-9321-z","volume":"82","author":"MC Hanse","year":"2007","unstructured":"Hanse MC, Vincent A, van den Bent MJ (2007) Hemangioblastomatosis in a patient with von Hippel\u2013Lindau disease. J Neurooncol 82:163\u2013164","journal-title":"J Neurooncol"},{"key":"827_CR9","doi-asserted-by":"crossref","first-page":"770","DOI":"10.1227\/00006123-198804000-00029","volume":"22","author":"EJ Kasarskis","year":"1998","unstructured":"Kasarskis EJ, Tibbs PA, Lee C (1998) Cerebellar hemangioblastoma symptomatic during pregnancy. Neurosurgery 22:770\u2013772","journal-title":"Neurosurgery"},{"key":"827_CR10","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1007\/s11060-004-2244-7","volume":"72","author":"M Kato","year":"2005","unstructured":"Kato M, Ohe N, Okumura A, Shinoda J, Nomura A, Shuin T, Sakai N (2005) Hemangioblastomatosis of the central nervous system without von Hippel\u2013Lindau disease: a case report. J Neurooncol 72:267\u2013270","journal-title":"J Neurooncol"},{"key":"827_CR11","doi-asserted-by":"crossref","first-page":"755","DOI":"10.3346\/jkms.2009.24.4.755","volume":"24","author":"HR Kim","year":"2009","unstructured":"Kim HR, Suh YL, Kim JW, Lee JI (2009) Disseminated hemangioblastomatosis of the central nervous system without von Hippel-Lindau disease: a case report. J Korean Med Sci 24:755\u2013759","journal-title":"J Korean Med Sci"},{"key":"827_CR12","doi-asserted-by":"crossref","first-page":"1317","DOI":"10.1126\/science.8493574","volume":"260","author":"F Latif","year":"1993","unstructured":"Latif F, Tory K, Gnarra J, Yao M, Duh FM, Orcutt ML, Stackhouse T, Kuzmin I, Modi W, Geil L, Schmidt L, Zhou FW, Li H, Wei MH, Chen F, Glenn G, Choyke P, Walther MM, Weng YK, Duan DSR, Dean M, Glavac D, Richards FM, Crossey PA, Ferguson-Smith MA, Le Paslier D, Chumakov I, Cohen D, Chinault AC, Maher ER, Linehan WM, Zbar B, Lerman MI (1993) Identification of the von Hippel-Lindau disease tumor suppressor gene. Science 260:1317\u20131320","journal-title":"Science"},{"key":"827_CR13","doi-asserted-by":"crossref","first-page":"2059","DOI":"10.1016\/S0140-6736(03)13643-4","volume":"361","author":"RR Lonser","year":"2003","unstructured":"Lonser RR, Glenn GM, Walther M, Chew EY, Libutti SK, Linehan WM, Oldfield EH (2003) Von Hippel-Lindau disease. Lancet 361:2059\u20132067","journal-title":"Lancet"},{"key":"827_CR14","doi-asserted-by":"crossref","first-page":"E37","DOI":"10.1542\/peds.109.2.e37","volume":"109","author":"JJ Marler","year":"2002","unstructured":"Marler JJ, Rubin JB, Trede NS, Connors S, Grier H, Upton J, Mulliken JB, Folkman J (2002) Successful antiangiogenic therapy of giant cell angioblastoma with interferon alfa 2B: report of 2 cases. Pediatrics 109:E37","journal-title":"Pediatrics"},{"key":"827_CR15","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1136\/jnnp.39.6.515","volume":"39","author":"J Mohan","year":"1976","unstructured":"Mohan J, Brownell B, Oppenheimer D (1976) Malignant spread of haemangioblastoma: report on two cases. J Neurol Neurosurg Psychiatry 39:515\u2013525","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"827_CR16","first-page":"662","volume":"40","author":"L Nathan","year":"1995","unstructured":"Nathan L, Satin AJ, Twickler DM (1995) Cerebellar hemangioblastoma complicating pregnancy. A case report. J Reprod Med 40:662\u2013664","journal-title":"J Reprod Med"},{"key":"827_CR17","first-page":"510","volume":"7","author":"M Niemel\u00e4","year":"2001","unstructured":"Niemel\u00e4 M, M\u00e4enp\u00e4\u00e4 H, Salven P (2001) Interferon \u03b1-2a therapy in 18 hemangioblastomas. Clin Cancer Res 7:510\u2013516","journal-title":"Clin Cancer Res"},{"key":"827_CR18","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1023\/B:NEON.0000014493.88402.dc","volume":"66","author":"M Piribauer","year":"2004","unstructured":"Piribauer M, Czech T, Dieckmann K, Birner P, Hainfellner JA, Prayer D, Fazeny-D\u00f6rner B, Weinl\u00e4nder G, Marosi C (2004) Stabilization of a progressive hemangioblastoma under treatment with thalidomide. J Neurooncol 66:295\u2013299","journal-title":"J Neurooncol"},{"key":"827_CR19","first-page":"1212","volume":"52","author":"N Reyns","year":"2003","unstructured":"Reyns N, Assaker R, Louis E, Lejeune JP (2003) Leptomeningeal hemangioblastomatosis in a case of von Hippel\u2013Lindau disease: case report. Neurosurgery 52:1212\u20131215, discussion 1215-1216","journal-title":"Neurosurgery"},{"key":"827_CR20","doi-asserted-by":"crossref","first-page":"3851","DOI":"10.1182\/blood.V99.10.3851","volume":"99","author":"S Richard","year":"2002","unstructured":"Richard S, Croisille L, Yvart J, Casadeval N, Eschw\u00e8ge P, Aghakhani N, David P, Gaudric A, Scigalla P, Hermine O (2002) Paradoxical secondary polycythemia in von Hippel-Lindau patients treated with antivascular endothelial growth factor receptor therapy. Blood 99:3851\u20133853","journal-title":"Blood"},{"key":"827_CR21","doi-asserted-by":"crossref","first-page":"82","DOI":"10.3171\/jns.2003.98.1.0082","volume":"98","author":"JE Wanebo","year":"2003","unstructured":"Wanebo JE, Lonser RR, Glenn GM, Oldfield EH (2003) The natural history of hemangioblastomas of the central nervous system in patients with von Hippel-Lindau disease. J Neurosurg 98:82\u201394","journal-title":"J Neurosurg"},{"key":"827_CR22","doi-asserted-by":"crossref","first-page":"775","DOI":"10.3171\/jns.2002.96.4.0775","volume":"96","author":"RJ Weil","year":"2002","unstructured":"Weil RJ, Vortmeyer AO, Zhuang Z, Pack SD, Theodore N, Erickson RK, Oldfield EH (2002) Clinical and molecular analysis of disseminated hemangioblastomatosis of the central nervous system in patients without von Hippel\u2013Lindau disease: report of four cases. J Neurosurg 96:775\u2013787","journal-title":"J Neurosurg"}],"container-title":["Acta Neurochirurgica"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00701-010-0827-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00701-010-0827-y\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00701-010-0827-y","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,29]],"date-time":"2019-05-29T00:16:30Z","timestamp":1559088990000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00701-010-0827-y"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,10,13]]},"references-count":22,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2011,1]]}},"alternative-id":["827"],"URL":"https:\/\/doi.org\/10.1007\/s00701-010-0827-y","relation":{},"ISSN":["0001-6268","0942-0940"],"issn-type":[{"value":"0001-6268","type":"print"},{"value":"0942-0940","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,10,13]]}}}