{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T17:42:00Z","timestamp":1790703720619,"version":"4.1.0"},"reference-count":29,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2016,12,23]],"date-time":"2016-12-23T00:00:00Z","timestamp":1482451200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Acta Neurochir"],"published-print":{"date-parts":[[2017,2]]},"DOI":"10.1007\/s00701-016-3054-3","type":"journal-article","created":{"date-parts":[[2016,12,24]],"date-time":"2016-12-24T15:55:58Z","timestamp":1482594958000},"page":"363-367","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":70,"title":["Fluorescein sodium-guided resection of cerebral metastases\u2014an update"],"prefix":"10.1007","volume":"159","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8238-2211","authenticated-orcid":false,"given":"Julius","family":"H\u00f6hne","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christoph","family":"Hohenberger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin","family":"Proescholdt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Markus J","family":"Riemenschneider","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christina","family":"Wendl","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexander","family":"Brawanski","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karl-Michael","family":"Schebesch","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2016,12,23]]},"reference":[{"key":"3054_CR1","doi-asserted-by":"crossref","first-page":"1959","DOI":"10.1007\/s00701-015-2553-y","volume":"157","author":"A Brawanski","year":"2015","unstructured":"Brawanski A, Acerbi F, Nakaji P, Cohen-Gadol A, Schebesch KM (2015) Poor man-rich man fluorescence. Is this really the problem? Acta Neurochir 157:1959\u20131961","journal-title":"Acta Neurochir"},{"key":"3054_CR2","doi-asserted-by":"crossref","first-page":"1360","DOI":"10.3171\/2015.2.JNS132507","volume":"122","author":"RJ Diaz","year":"2015","unstructured":"Diaz RJ, Dios RR, Hattab EM, Burrell K, Rakopoulos P, Sabha N, Hawkins C, Zadeh G, Rutka JT, Cohen-Gadol AA (2015) Study of the biodistribution of fluorescein in glioma-infiltrated mouse brain and histopathological correlation of intraoperative findings in high-grade gliomas resected under fluorescein fluorescence guidance. J Neurosurg 122:1360\u20131369","journal-title":"J Neurosurg"},{"key":"3054_CR3","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1007\/978-3-211-99651-5_40","volume":"109","author":"P Ferroli","year":"2011","unstructured":"Ferroli P, Acerbi F, Albanese E, Tringali G, Broggi M, Franzini A, Broggi G (2011) Application of intraoperative indocyanine green angiography for CNS tumors: results on the first 100 cases. Acta Neurochir Suppl 109:251\u2013257","journal-title":"Acta Neurochir Suppl"},{"key":"3054_CR4","doi-asserted-by":"crossref","first-page":"897","DOI":"10.1007\/s00701-015-2404-x","volume":"157","author":"J Gempt","year":"2015","unstructured":"Gempt J, Meyer B (2015) Does fluorescein sodium-guided resection of cerebral metastases increase rates of total resections? Acta Neurochir 157:897","journal-title":"Acta Neurochir"},{"key":"3054_CR5","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/j.clineuro.2016.02.006","volume":"143","author":"MK Hamamcioglu","year":"2016","unstructured":"Hamamcioglu MK, Akcakaya MO, Goker B, Kasimcan MO, Kiris T (2016) The use of the YELLOW 560nm surgical microscope filter for sodium fluorescein-guided resection of brain tumors: Our preliminary results in a series of 28 patients. Clin Neurol Neurosurg 143:39\u201345","journal-title":"Clin Neurol Neurosurg"},{"key":"3054_CR6","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1007\/s11060-009-0065-4","volume":"96","author":"SN Kalkanis","year":"2010","unstructured":"Kalkanis SN, Linskey ME (2010) Evidence-based clinical practice parameter guidelines for the treatment of patients with metastatic brain tumors: introduction. J Neuro-Oncol 96:7\u201310","journal-title":"J Neuro-Oncol"},{"key":"3054_CR7","doi-asserted-by":"crossref","unstructured":"Kamp M, Fischer I, B\u00fchner J, Turowski B, Cornelius JF, Steiger HJ, Rapp M, Slotty PJ, Sabel M (2016) 5-ALA fluorescence of cerebral metastases and its impact for the local-in-brain progression.\u00a0Oncotarget 7(41):66776\u201366789","DOI":"10.18632\/oncotarget.11488"},{"key":"3054_CR8","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1007\/s00701-011-1200-5","volume":"154","author":"MA Kamp","year":"2012","unstructured":"Kamp MA, Grosser P, Felsberg J, Slotty PJ, Steiger HJ, Reifenberger G, Sabel M (2012) 5-amin olevulinic acid (5-ALA)-induced fluorescence in intracerebral metastases: a retrospective study. Acta Neurochir 154:223\u2013228, discussion 228","journal-title":"Acta Neurochir"},{"key":"3054_CR9","doi-asserted-by":"crossref","first-page":"629","DOI":"10.3109\/02688697.2013.815313","volume":"27","author":"L Lee","year":"2013","unstructured":"Lee L, Ker J, Quah BL, Chou N, Choy D, Yeo TT (2013) A retrospective analysis and review of an institution\u2019s experience with the complications of cranioplasty. Br J Neurosurg 27:629\u2013635","journal-title":"Br J Neurosurg"},{"key":"3054_CR10","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1016\/j.wneu.2013.06.014","volume":"82","author":"Y Li","year":"2014","unstructured":"Li Y, Rey-Dios R, Roberts DW, Valdes PA, Cohen-Gadol AA (2014) Intraoperative fluorescence-guided resection of high-grade gliomas: a comparison of the present techniques and evolution of future strategies. World Neurosurg 82:175\u2013185","journal-title":"World Neurosurg"},{"key":"3054_CR11","doi-asserted-by":"crossref","first-page":"E10","DOI":"10.3171\/2013.12.FOCUS13464","volume":"36","author":"S Marbacher","year":"2014","unstructured":"Marbacher S, Klinger E, Schwyzer L, Fischer I, Nevzati E, Diepers M, Roelcke U, Fathi AR, Coluccia D, Fandino J (2014) Use of fluorescence to guide resection or biopsy of primary brain tumors and brain metastases. Neurosurg Focus 36:E10","journal-title":"Neurosurg Focus"},{"key":"3054_CR12","doi-asserted-by":"crossref","first-page":"E11","DOI":"10.3171\/2016.1.FOCUS15559","volume":"40","author":"NL Martirosyan","year":"2016","unstructured":"Martirosyan NL, Eschbacher JM, Kalani MY, Turner JD, Belykh E, Spetzler RF, Nakaji P, Preul MC (2016) Prospective evaluation of the utility of intraoperative confocal laser endomicroscopy in patients with brain neoplasms using fluorescein sodium: experience with 74 cases. Neurosurg Focus 40:E11","journal-title":"Neurosurg Focus"},{"key":"3054_CR13","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1126\/science.106.2745.130-a","volume":"106","author":"GE Moore","year":"1947","unstructured":"Moore GE (1947) Fluorescein as an agent in the differentiation of normal and malignant tissues. Science 106:130\u2013131","journal-title":"Science"},{"key":"3054_CR14","doi-asserted-by":"crossref","first-page":"427","DOI":"10.3171\/2013.3.JNS122226","volume":"119","author":"EK Nduom","year":"2013","unstructured":"Nduom EK, Yang C, Merrill MJ, Zhuang Z, Lonser RR (2013) Characterization of the blood\u2013brain barrier of metastatic and primary malignant neoplasms. J Neurosurg 119:427\u2013433","journal-title":"J Neurosurg"},{"key":"3054_CR15","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1055\/s-2007-993200","volume":"50","author":"T Okuda","year":"2007","unstructured":"Okuda T, Kataoka K, Taneda M (2007) Metastatic brain tumor surgery using fluorescein sodium: technical note. Minimally Invasive Neurosurg: MIN 50:382\u2013384","journal-title":"Minimally Invasive Neurosurg: MIN"},{"key":"3054_CR16","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1016\/j.jocn.2009.06.033","volume":"17","author":"T Okuda","year":"2010","unstructured":"Okuda T, Kataoka K, Yabuuchi T, Yugami H, Kato A (2010) Fluorescence-guided surgery of metastatic brain tumors using fluorescein sodium. J Clin Neurosci: Off J Neurosurg Soc Australasia 17:118\u2013121","journal-title":"J Clin Neurosci: Off J Neurosurg Soc Australasia"},{"key":"3054_CR17","doi-asserted-by":"crossref","first-page":"1485","DOI":"10.1001\/jama.280.17.1485","volume":"280","author":"RA Patchell","year":"1998","unstructured":"Patchell RA, Tibbs PA, Regine WF, Dempsey RJ, Mohiuddin M, Kryscio RJ, Markesbery WR, Foon KA, Young B (1998) Postoperative radiotherapy in the treatment of single metastases to the brain: a randomized trial. JAMA 280:1485\u20131489","journal-title":"JAMA"},{"key":"3054_CR18","doi-asserted-by":"crossref","first-page":"494","DOI":"10.1056\/NEJM199002223220802","volume":"322","author":"RA Patchell","year":"1990","unstructured":"Patchell RA, Tibbs PA, Walsh JW, Dempsey RJ, Maruyama Y, Kryscio RJ, Markesbery WR, Macdonald JS, Young B (1990) A randomized trial of surgery in the treatment of single metastases to the brain. N Engl J Med 322:494\u2013500","journal-title":"N Engl J Med"},{"key":"3054_CR19","doi-asserted-by":"crossref","first-page":"701","DOI":"10.1007\/s00701-013-1635-y","volume":"155","author":"R Rey-Dios","year":"2013","unstructured":"Rey-Dios R, Cohen-Gadol AA (2013) Technical principles and neurosurgical applications of fluorescein fluorescence using a microscope-integrated fluorescence module. Acta Neurochir 155:701\u2013706","journal-title":"Acta Neurochir"},{"key":"3054_CR20","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1007\/s00701-012-1606-8","volume":"155","author":"G Schackert","year":"2013","unstructured":"Schackert G, Lindner C, Petschke S, Leimert M, Kirsch M (2013) Retrospective study of 127 surgically treated patients with multiple brain metastases: indication, prognostic factors, and outcome. Acta Neurochir 155:379\u2013387","journal-title":"Acta Neurochir"},{"key":"3054_CR21","first-page":"246","volume":"24","author":"G Schackert","year":"2001","unstructured":"Schackert G, Steinmetz A, Meier U, Sobottka SB (2001) Surgical management of single and multiple brain metastases: results of a retrospective study. Onkologie 24:246\u2013255","journal-title":"Onkologie"},{"key":"3054_CR22","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1016\/j.clineuro.2015.09.015","volume":"139","author":"KM Schebesch","year":"2015","unstructured":"Schebesch KM, Hoehne J, Hohenberger C, Acerbi F, Broggi M, Proescholdt M, Wendl C, Riemenschneider MJ, Brawanski A (2015) Fluorescein sodium-guided surgery in cerebral lymphoma. Clin Neurol Neurosurg 139:125\u2013128","journal-title":"Clin Neurol Neurosurg"},{"key":"3054_CR23","doi-asserted-by":"crossref","first-page":"899","DOI":"10.1007\/s00701-015-2395-7","volume":"157","author":"KM Schebesch","year":"2015","unstructured":"Schebesch KM, Hoehne J, Hohenberger C, Proescholdt M, Riemenschneider MJ, Wendl C, Brawanski A (2015) Fluorescein sodium-guided resection of cerebral metastases-experience with the first 30 patients. Acta Neurochir 157:899\u2013904","journal-title":"Acta Neurochir"},{"key":"3054_CR24","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1007\/s00701-013-1643-y","volume":"155","author":"KM Schebesch","year":"2013","unstructured":"Schebesch KM, Proescholdt M, Hohne J, Hohenberger C, Hansen E, Riemenschneider MJ, Ullrich W, Doenitz C, Schlaier J, Lange M, Brawanski A (2013) Sodium fluorescein-guided resection under the YELLOW 560 nm surgical microscope filter in malignant brain tumor surgery\u2014a feasibility study. Acta Neurochir 155:693\u2013699","journal-title":"Acta Neurochir"},{"key":"3054_CR25","doi-asserted-by":"crossref","first-page":"8708","DOI":"10.3390\/ijms14058708","volume":"14","author":"P Schodel","year":"2013","unstructured":"Schodel P, Schebesch KM, Brawanski A, Proescholdt MA (2013) Surgical resection of brain metastases-impact on neurological outcome. Int J Mol Sci 14:8708\u20138718","journal-title":"Int J Mol Sci"},{"key":"3054_CR26","doi-asserted-by":"crossref","first-page":"1379","DOI":"10.1007\/s00701-015-2471-z","volume":"157","author":"W Stummer","year":"2015","unstructured":"Stummer W (2015) Poor man\u2019s fluorescence? Acta Neurochir 157:1379\u20131381","journal-title":"Acta Neurochir"},{"key":"3054_CR27","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1007\/s10014-007-0223-3","volume":"24","author":"S Utsuki","year":"2007","unstructured":"Utsuki S, Miyoshi N, Oka H, Miyajima Y, Shimizu S, Suzuki S, Fujii K (2007) Fluorescence-guided resection of metastatic brain tumors using a 5-aminolevulinic acid-induced protoporphyrin IX: pathological study. Brain Tumor Pathol 24:53\u201355","journal-title":"Brain Tumor Pathol"},{"key":"3054_CR28","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1002\/ana.410330605","volume":"33","author":"CJ Vecht","year":"1993","unstructured":"Vecht CJ, Haaxma-Reiche H, Noordijk EM, Padberg GW, Voormolen JH, Hoekstra FH, Tans JT, Lambooij N, Metsaars JA, Wattendorff AR et al (1993) Treatment of single brain metastasis: radiotherapy alone or combined with neurosurgery? Ann Neurol 33:583\u2013590","journal-title":"Ann Neurol"},{"key":"3054_CR29","doi-asserted-by":"crossref","first-page":"4196","DOI":"10.1038\/ncomms5196","volume":"5","author":"S Watkins","year":"2014","unstructured":"Watkins S, Robel S, Kimbrough IF, Robert SM, Ellis-Davies G, Sontheimer H (2014) Disruption of astrocyte-vascular coupling and the blood\u2013brain barrier by invading glioma cells. Nat Commun 5:4196","journal-title":"Nat Commun"}],"container-title":["Acta Neurochirurgica"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00701-016-3054-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00701-016-3054-3\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00701-016-3054-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,6,25]],"date-time":"2017-06-25T02:42:46Z","timestamp":1498358566000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00701-016-3054-3"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,12,23]]},"references-count":29,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2017,2]]}},"alternative-id":["3054"],"URL":"https:\/\/doi.org\/10.1007\/s00701-016-3054-3","relation":{},"ISSN":["0001-6268","0942-0940"],"issn-type":[{"value":"0001-6268","type":"print"},{"value":"0942-0940","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,12,23]]}}}