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Most meningiomas are benign, and most patients are 65\u00a0years or older. Surgery is usually the primary treatment option. Most prior studies on early surgical outcomes in older patients with meningioma are small, and there is a lack of larger population-based studies to guide clinical decision-making. We aimed to explore the risks for perioperative mortality and morbidity in older patients with meningioma and to investigate changes in surgical incidence over time.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methods<\/jats:title>\n                <jats:p>In this retrospective population-based study on patients in Sweden, 65\u00a0years or older with surgery 1999\u20132017 for meningioma, we used data from the Swedish Brain Tumour Registry. We analysed factors contributing to perioperative mortality and morbidity and used official demographic data to calculate yearly incidence of surgical procedures for meningioma.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>The final study cohort included 1676 patients with a 3.1% perioperative mortality and a 37.6% perioperative morbidity. In multivariate analysis, higher age showed a statistically significant association with higher perioperative mortality, whereas larger tumour size and having preoperative symptoms were associated with higher perioperative morbidity. A numerical increased rate of surgical interventions after 2012 was observed, without evidence of worsening short-term surgical outcomes.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusions<\/jats:title>\n                <jats:p>Higher mortality with increased age and higher morbidity risk in larger and\/or symptomatic tumours imply a possible benefit from considering surgery in selected older patients with a growing meningioma before the development of tumour-related symptoms. This study further underlines the need for a standardized method of reporting and classifying complications from neurosurgery.\n<\/jats:p>\n              <\/jats:sec>","DOI":"10.1007\/s00701-022-05336-1","type":"journal-article","created":{"date-parts":[[2022,8,18]],"date-time":"2022-08-18T02:02:40Z","timestamp":1660788160000},"page":"2987-2997","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Older meningioma patients: a retrospective population-based study of risk factors for morbidity and mortality after neurosurgery"],"prefix":"10.1007","volume":"164","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9858-6684","authenticated-orcid":false,"given":"David","family":"L\u00f6fgren","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6059-0194","authenticated-orcid":false,"given":"Antonios","family":"Valachis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8457-4711","authenticated-orcid":false,"given":"Magnus","family":"Olivecrona","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2022,8,18]]},"reference":[{"key":"5336_CR1","doi-asserted-by":"publisher","first-page":"709","DOI":"10.1016\/j.jgo.2019.10.017","volume":"11","author":"A Albert","year":"2020","unstructured":"Albert A, Lee A, Thomas TV, Vijayakumar S (2020) Outcomes of benign meningioma in older patients in the United States. 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All procedures performed were in accordance with the approval and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval"}},{"value":"In accordance with Swedish legislation and regulations regarding patient consent for participation in a national quality registry, before undergoing surgery, patients were given written information about SBTR including the choice to opt out from registration in SBTR or for their data to be removed from the registry at any time.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to participate"}},{"value":"David L\u00f6fgren and Magnus Olivecrona are members of the Swedish CNS Tumour Registry control group. Magnus Olivecrona is a previous member of the Swedish Brain Tumour Registry (SBTR) control group. Antonios Valachis reports no conflict of interest.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}