{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,23]],"date-time":"2026-06-23T22:34:57Z","timestamp":1782254097234,"version":"3.54.5"},"reference-count":48,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2022,12,22]],"date-time":"2022-12-22T00:00:00Z","timestamp":1671667200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2022,12,22]],"date-time":"2022-12-22T00:00:00Z","timestamp":1671667200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Acta Neurochir"],"DOI":"10.1007\/s00701-022-05454-w","type":"journal-article","created":{"date-parts":[[2022,12,22]],"date-time":"2022-12-22T04:21:19Z","timestamp":1671682879000},"page":"211-220","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Stereotactic radiosurgery for Koos grade IV vestibular schwannoma in patients\u2009\u2265\u200965\u00a0years old: a multi-institutional retrospective study"],"prefix":"10.1007","volume":"165","author":[{"given":"Chloe","family":"Dumot","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stylianos","family":"Pikis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Georgios","family":"Mantziaris","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhiyuan","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sam","family":"Dayawansa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rithika Kormath","family":"Anand","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahmed M.","family":"Nabeel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Darrah","family":"Sheehan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kimball","family":"Sheehan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wael A.","family":"Reda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sameh R.","family":"Tawadros","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Khaled Abdel","family":"Karim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amr M. N.","family":"El-Shehaby","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Reem M. Emad","family":"Eldin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Selcuk","family":"Peker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yavuz","family":"Samanci","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tehila","family":"Kaisman-Elbaz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Herwin","family":"Speckter","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenceslao","family":"Hern\u00e1ndez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julio","family":"Isidor","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manjul","family":"Tripathi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Renu","family":"Madan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brad E.","family":"Zacharia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lekhaj C.","family":"Daggubati","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nuria Mart\u00ednez","family":"Moreno","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roberto Mart\u00ednez","family":"\u00c1lvarez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne-Marie","family":"Langlois","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Mathieu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher P.","family":"Deibert","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vivek R.","family":"Sudhakar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher P.","family":"Cifarelli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Denisse Arteaga","family":"Icaza","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel T.","family":"Cifarelli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhishuo","family":"Wei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ajay","family":"Niranjan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gene H.","family":"Barnett","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L. Dade","family":"Lunsford","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Greg N.","family":"Bowden","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jason P.","family":"Sheehan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2022,12,22]]},"reference":[{"key":"5454_CR1","doi-asserted-by":"publisher","first-page":"487","DOI":"10.1016\/j.wneu.2016.07.117","volume":"95","author":"M Bailo","year":"2016","unstructured":"Bailo M, Boari N, Franzin A, Gagliardi F, Spina A, Del Vecchio A, Gemma M, Bolognesi A, Mortini P (2016) Gamma Knife radiosurgery as primary treatment for large vestibular schwannomas: clinical results at long-term follow-up in a series of 59 patients. World Neurosurg 95:487\u2013501","journal-title":"World Neurosurg"},{"key":"5454_CR2","doi-asserted-by":"publisher","first-page":"43","DOI":"10.3389\/fneur.2019.00043","volume":"10","author":"J Bartek","year":"2019","unstructured":"Bartek J, F\u00f6rander P, Thurin E, Wangerid T, Henriksson R, Hesselager G, Jakola AS (2019) Short-term surgical outcome for vestibular schwannoma in Sweden: a nation-wide registry study. Front Neurol 10:43","journal-title":"Front Neurol"},{"issue":"10033","key":"5454_CR3","doi-asserted-by":"publisher","first-page":"2145","DOI":"10.1016\/S0140-6736(15)00516-4","volume":"387","author":"JR Beard","year":"2016","unstructured":"Beard JR, Officer A, de Carvalho IA et al (2016) The world report on ageing and health: a policy framework for healthy ageing. Lancet Lond Engl 387(10033):2145\u20132154","journal-title":"Lancet Lond Engl"},{"key":"5454_CR4","doi-asserted-by":"publisher","first-page":"58","DOI":"10.1016\/j.wneu.2016.08.054","volume":"96","author":"CA Bowers","year":"2016","unstructured":"Bowers CA, Gurgel RK, Brimley C, Hawryluk GWJ, Taggart M, Braden S, Collett T, Gale D, Salzman KL, MacDonald JD (2016) Surgical treatment of vestibular schwannoma: does age matter? World Neurosurg 96:58\u201365","journal-title":"World Neurosurg"},{"issue":"5","key":"5454_CR5","first-page":"762","volume":"45","author":"M Bretonnier","year":"2020","unstructured":"Bretonnier M, Bernard F, Tinois J, Troude L, Cebula H, Godey B, Morandi X (2020) Functional sparing surgery policy for giant vestibular schwannomas. Clin Otolaryngol Off J ENT-UK Off J Neth Soc Oto-Rhino-Laryngol Cervico-Facial Surg 45(5):762\u2013767","journal-title":"Clin Otolaryngol Off J ENT-UK Off J Neth Soc Oto-Rhino-Laryngol Cervico-Facial Surg"},{"issue":"4","key":"5454_CR6","doi-asserted-by":"publisher","first-page":"969","DOI":"10.1007\/s00701-020-04667-1","volume":"163","author":"A Bunevicius","year":"2021","unstructured":"Bunevicius A, Pikis S, Schlesinger D, Sheehan J (2021) Editorial: radiosurgical induced malignancy associated with stereotactic radiosurgery. Acta Neurochir (Wien) 163(4):969\u2013970","journal-title":"Acta Neurochir (Wien)"},{"issue":"5","key":"5454_CR7","doi-asserted-by":"publisher","first-page":"967","DOI":"10.1016\/S0360-3016(97)00364-7","volume":"39","author":"J Debus","year":"1997","unstructured":"Debus J, Hug EB, Liebsch NJ, O\u2019Farrel D, Finkelstein D, Efird J, Munzenrider JE (1997) Brainstem tolerance to conformal radiotherapy of skull base tumors. Int J Radiat Oncol Biol Phys 39(5):967\u2013975","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"5454_CR8","doi-asserted-by":"publisher","first-page":"93","DOI":"10.1159\/000156712","volume":"21","author":"C Delsanti","year":"2008","unstructured":"Delsanti C, Roche P-H, Thomassin J-M, R\u00e9gis J (2008) Morphological changes of vestibular schwannomas after radiosurgical treatment: pitfalls and diagnosis of failure. Prog Neurol Surg 21:93\u201397","journal-title":"Prog Neurol Surg"},{"key":"5454_CR9","doi-asserted-by":"publisher","DOI":"10.1007\/s11060-022-04134-0","author":"C Dumot","year":"2022","unstructured":"Dumot C, Pikis S, Mantziaris G et al (2022) Stereotactic radiosurgery for Koos grade IV vestibular schwannoma in young patients: a multi-institutional study. J Neurooncol. https:\/\/doi.org\/10.1007\/s11060-022-04134-0","journal-title":"J Neurooncol"},{"issue":"7","key":"5454_CR10","doi-asserted-by":"publisher","first-page":"1213","DOI":"10.1007\/s00701-017-3216-y","volume":"159","author":"P Ferroli","year":"2017","unstructured":"Ferroli P, Bosio L, Broggi M (2017) Facial nerve sparing surgery for large vestibular schwannomas. Acta Neurochir (Wien) 159(7):1213\u20131218","journal-title":"Acta Neurochir (Wien)"},{"issue":"1","key":"5454_CR11","doi-asserted-by":"publisher","first-page":"55","DOI":"10.1177\/000348948809700110","volume":"97","author":"G Gardner","year":"1988","unstructured":"Gardner G, Robertson JH (1988) Hearing preservation in unilateral acoustic neuroma surgery. Ann Otol Rhinol Laryngol 97(1):55\u201366","journal-title":"Ann Otol Rhinol Laryngol"},{"issue":"1","key":"5454_CR12","doi-asserted-by":"publisher","first-page":"31","DOI":"10.1093\/neuonc\/noz153","volume":"22","author":"R Goldbrunner","year":"2020","unstructured":"Goldbrunner R, Weller M, Regis J et al (2020) EANO guideline on the diagnosis and treatment of vestibular schwannoma. Neuro-Oncol 22(1):31\u201345","journal-title":"Neuro-Oncol"},{"issue":"6","key":"5454_CR13","doi-asserted-by":"publisher","first-page":"1472","DOI":"10.3171\/2015.12.JNS151857","volume":"125","author":"JG Golfinos","year":"2016","unstructured":"Golfinos JG, Hill TC, Rokosh R, Choudhry O, Shinseki M, Mansouri A, Friedmann DR, Thomas Roland J, Kondziolka D (2016) A matched cohort comparison of clinical outcomes following microsurgical resection or stereotactic radiosurgery for patients with small- and medium-sized vestibular schwannomas. J Neurosurg 125(6):1472\u20131482","journal-title":"J Neurosurg"},{"issue":"4","key":"5454_CR14","doi-asserted-by":"publisher","first-page":"2119","DOI":"10.1007\/s10143-020-01380-6","volume":"44","author":"G Grinblat","year":"2021","unstructured":"Grinblat G, Dandinarasaiah M, Braverman I, Taibah A, Lisma DG, Sanna M (2021) Large and giant vestibular schwannomas: overall outcomes and the factors influencing facial nerve function. Neurosurg Rev 44(4):2119\u20132131","journal-title":"Neurosurg Rev"},{"issue":"3","key":"5454_CR15","doi-asserted-by":"publisher","first-page":"557","DOI":"10.3171\/2012.10.JNS12523","volume":"118","author":"T Hasegawa","year":"2013","unstructured":"Hasegawa T, Kida Y, Kato T, Iizuka H, Kuramitsu S, Yamamoto T (2013) Long-term safety and efficacy of stereotactic radiosurgery for vestibular schwannomas: evaluation of 440 patients more than 10 years after treatment with Gamma Knife surgery. J Neurosurg 118(3):557\u2013565","journal-title":"J Neurosurg"},{"issue":"2","key":"5454_CR16","doi-asserted-by":"publisher","first-page":"145","DOI":"10.1007\/s11060-020-03622-5","volume":"151","author":"T Hasegawa","year":"2021","unstructured":"Hasegawa T, Kato T, Naito T, Tanei T, Ishii K, Tsukamoto E, Okada K, Ito R, Kouketsu Y (2021) Predictors of long-term tumor control after stereotactic radiosurgery for Koos grade 4 vestibular schwannomas. J Neurooncol 151(2):145\u2013156","journal-title":"J Neurooncol"},{"issue":"3","key":"5454_CR17","doi-asserted-by":"publisher","first-page":"104","DOI":"10.1093\/ons\/opab170","volume":"21","author":"A Helal","year":"2021","unstructured":"Helal A, Graffeo CS, Perry A, Van Abel KM, Carlson ML, Neff BA, Driscoll CLW, Link MJ (2021) Differential impact of advanced age on clinical outcomes after vestibular schwannoma resection in the very elderly: cohort study. Oper Neurosurg Hagerstown Md 21(3):104\u2013110","journal-title":"Oper Neurosurg Hagerstown Md"},{"issue":"2","key":"5454_CR18","doi-asserted-by":"publisher","first-page":"146","DOI":"10.1177\/019459988509300202","volume":"93","author":"JW House","year":"1985","unstructured":"House JW, Brackmann DE (1985) Facial nerve grading system. Otolaryngol-Head Neck Surg Off J Am Acad Otolaryngol-Head Neck Surg 93(2):146\u2013147","journal-title":"Otolaryngol-Head Neck Surg Off J Am Acad Otolaryngol-Head Neck Surg"},{"issue":"5","key":"5454_CR19","doi-asserted-by":"publisher","first-page":"1380","DOI":"10.3171\/2016.12.JNS161530","volume":"128","author":"C-W Huang","year":"2018","unstructured":"Huang C-W, Tu H-T, Chuang C-Y, Chang C-S, Chou H-H, Lee M-T, Huang C-F (2018) Gamma Knife radiosurgery for large vestibular schwannomas greater than 3 cm in diameter. J Neurosurg 128(5):1380\u20131387","journal-title":"J Neurosurg"},{"issue":"4","key":"5454_CR20","doi-asserted-by":"publisher","first-page":"521","DOI":"10.1227\/NEU.0000000000001154","volume":"78","author":"C Iorio-Morin","year":"2016","unstructured":"Iorio-Morin C, AlSubaie F, Mathieu D (2016) Safety and efficacy of gamma knife radiosurgery for the management of Koos grade 4 vestibular schwannomas. Neurosurgery 78(4):521\u2013530","journal-title":"Neurosurgery"},{"key":"5454_CR21","doi-asserted-by":"publisher","first-page":"457","DOI":"10.1016\/j.wneu.2017.01.120","volume":"101","author":"N Jiang","year":"2017","unstructured":"Jiang N, Wang Z, Chen W, Xie Y, Peng Z, Yuan J, Wanggou S, Su Y, Li X, Yuan X (2017) Microsurgical outcomes after gross total resection on vestibular schwannoma in elderly patients: a matched cohort study. World Neurosurg 101:457\u2013465","journal-title":"World Neurosurg"},{"issue":"4","key":"5454_CR22","doi-asserted-by":"publisher","first-page":"863","DOI":"10.3171\/2008.12.JNS08611","volume":"111","author":"H Kano","year":"2009","unstructured":"Kano H, Kondziolka D, Khan A, Flickinger JC, Lunsford LD (2009) Predictors of hearing preservation after stereotactic radiosurgery for acoustic neuroma. J Neurosurg 111(4):863\u2013873","journal-title":"J Neurosurg"},{"issue":"1","key":"5454_CR23","doi-asserted-by":"publisher","first-page":"93","DOI":"10.1007\/s11060-021-03803-w","volume":"154","author":"M Kawashima","year":"2021","unstructured":"Kawashima M, Hasegawa H, Shin M, Shinya Y, Katano A, Saito N (2021) Outcomes of stereotactic radiosurgery in young adults with vestibular schwannomas. J Neurooncol 154(1):93\u2013100","journal-title":"J Neurooncol"},{"issue":"2","key":"5454_CR24","doi-asserted-by":"publisher","first-page":"223","DOI":"10.1007\/s11060-015-1827-9","volume":"124","author":"VR Kshettry","year":"2015","unstructured":"Kshettry VR, Hsieh JK, Ostrom QT, Kruchko C, Barnholtz-Sloan JS (2015) Incidence of vestibular schwannomas in the United States. J Neurooncol 124(2):223\u2013228","journal-title":"J Neurooncol"},{"issue":"3 Suppl","key":"5454_CR25","doi-asserted-by":"publisher","first-page":"S20","DOI":"10.1016\/j.ijrobp.2009.02.091","volume":"76","author":"YR Lawrence","year":"2010","unstructured":"Lawrence YR, Li XA, el Naqa I, Hahn CA, Marks LB, Merchant TE, Dicker AP (2010) Radiation dose-volume effects in the brain. Int J Radiat Oncol Biol Phys 76(3 Suppl):S20-27","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"5454_CR26","doi-asserted-by":"publisher","first-page":"e1192","DOI":"10.1016\/j.wneu.2018.03.175","volume":"114","author":"M Lefranc","year":"2018","unstructured":"Lefranc M, Da Roz LM, Balossier A, Thomassin JM, Roche PH, Regis J (2018) Place of gamma knife stereotactic radiosurgery in grade 4 vestibular schwannoma based on case series of 86 patients with long-term follow-up. World Neurosurg 114:e1192\u2013e1198","journal-title":"World Neurosurg"},{"issue":"Suppl","key":"5454_CR27","doi-asserted-by":"publisher","first-page":"195","DOI":"10.3171\/sup.2005.102.s_supplement.0195","volume":"102","author":"LD Lunsford","year":"2005","unstructured":"Lunsford LD, Niranjan A, Flickinger JC, Maitz A, Kondziolka D (2005) Radiosurgery of vestibular schwannomas: summary of experience in 829 cases. J Neurosurg 102(Suppl):195\u2013199","journal-title":"J Neurosurg"},{"issue":"9","key":"5454_CR28","doi-asserted-by":"publisher","first-page":"e1358","DOI":"10.1097\/MAO.0000000000003251","volume":"42","author":"AL Luryi","year":"2021","unstructured":"Luryi AL, Babu S, Bojrab DI, Kveton JF, Schutt CA (2021) Surgical outcomes after conservative resection of vestibular schwannoma in the elderly. Otol Neurotol Off Publ Am Otol Soc Am Neurotol Soc Eur Acad Otol Neurotol 42(9):e1358\u2013e1361","journal-title":"Otol Neurotol Off Publ Am Otol Soc Am Neurotol Soc Eur Acad Otol Neurotol"},{"key":"5454_CR29","doi-asserted-by":"publisher","first-page":"101","DOI":"10.1016\/j.wneu.2016.01.089","volume":"89","author":"BA McCutcheon","year":"2016","unstructured":"McCutcheon BA, Grauberger J, Murphy M et al (2016) Is patient age associated with perioperative outcomes after surgical resection of benign cranial nerve neoplasms? World Neurosurg 89:101\u2013107","journal-title":"World Neurosurg"},{"issue":"1","key":"5454_CR30","doi-asserted-by":"publisher","first-page":"71","DOI":"10.1007\/s00701-012-1553-4","volume":"155","author":"T Mindermann","year":"2013","unstructured":"Mindermann T, Schlegel I (2013) Grading of vestibular schwannomas and corresponding tumor volumes: ramifications for radiosurgery. Acta Neurochir (Wien) 155(1):71\u201374 (discussion 74)","journal-title":"Acta Neurochir (Wien)"},{"issue":"Suppl","key":"5454_CR31","doi-asserted-by":"publisher","first-page":"122","DOI":"10.3171\/2010.8.GKS10960","volume":"113","author":"O Nagano","year":"2010","unstructured":"Nagano O, Serizawa T, Higuchi Y, Matsuda S, Sato M, Yamakami I, Okiyama K, Ono J, Saeki N (2010) Tumor shrinkage of vestibular schwannomas after Gamma Knife surgery: results after more than 5 years of follow-up. J Neurosurg 113(Suppl):122\u2013127","journal-title":"J Neurosurg"},{"key":"5454_CR32","doi-asserted-by":"publisher","unstructured":"Ogino A, Lunsford LD, Long H, Johnson S, Faramand A, Niranjan A, Flickinger JC, Kano H (2021) Stereotactic radiosurgery as the primary management for patients with Koos grade IV vestibular schwannomas. Published online February 12, 2021. J Neurosurg 1\u20139. https:\/\/doi.org\/10.3171\/2020.8.JNS201832","DOI":"10.3171\/2020.8.JNS201832"},{"issue":"1","key":"5454_CR33","doi-asserted-by":"publisher","first-page":"215","DOI":"10.1227\/00006123-199501000-00036","volume":"36","author":"BE Pollock","year":"1995","unstructured":"Pollock BE, Lunsford LD, Kondziolka D, Flickinger JC, Bissonette DJ, Kelsey SF, Jannetta PJ (1995) Outcome analysis of acoustic neuroma management: a comparison of microsurgery and stereotactic radiosurgery. Neurosurgery 36(1):215\u2013224 (discussion 224-229)","journal-title":"Neurosurgery"},{"issue":"Suppl","key":"5454_CR34","first-page":"144","volume":"117","author":"M Quigg","year":"2012","unstructured":"Quigg M, Yen C-P, Chatman M, Quigg AH, McNeill IT, Macneill IT, Przybylowski CJ, Yan G, Sheehan JP (2012) Risks of history of diabetes mellitus, hypertension, and other factors related to radiation-induced changes following Gamma Knife surgery for cerebral arteriovenous malformations. J Neurosurg 117(Suppl):144\u2013149","journal-title":"J Neurosurg"},{"key":"5454_CR35","unstructured":"R Core Team (n.d.) R: A language and environment for statistical computing. R Foundation for Statistical Computing. https:\/\/www.r-project.org"},{"issue":"1","key":"5454_CR36","doi-asserted-by":"publisher","first-page":"274","DOI":"10.1186\/s13014-020-01714-0","volume":"15","author":"D Rue\u00df","year":"2020","unstructured":"Rue\u00df D, Weyer V, Tutunji J, Grau S, Kocher M, Hoevels M, Treuer H, Baues C, Ruge MI (2020) Stereotactic radiosurgery of benign brain tumors in elderly patients: evaluation of outcome and toxicity. Radiat Oncol Lond Engl 15(1):274\u00a0https:\/\/doi.org\/10.1186\/s13014-020-01714-0","journal-title":"Radiat Oncol Lond Engl"},{"key":"5454_CR37","doi-asserted-by":"publisher","first-page":"102","DOI":"10.1016\/j.wneu.2021.11.083","volume":"160","author":"AR Savardekar","year":"2022","unstructured":"Savardekar AR, Terrell D, Lele SJ, Diaz R, Keesari PR, Trosclair K, Kosty J, Wang CJ, Gardner G, Guthikonda B (2022) Primary treatment of small to medium (<3 cm) sporadic vestibular schwannomas: a systematic review and meta-analysis on hearing preservation and tumor control rates for microsurgery versus radiosurgery. World Neurosurg 160:102-113.e12","journal-title":"World Neurosurg"},{"key":"5454_CR38","doi-asserted-by":"publisher","DOI":"10.3171\/2022.4.JNS22203","author":"P Stylianos","year":"2022","unstructured":"Stylianos P, Mantziaris G, Rithika KA et al (2022) Stereotactic radiosurgery for Koos grade IV vestibular schwannoma a multi-institutional study. J Neurosurg 1\u20138.\u00a0https:\/\/doi.org\/10.3171\/2022.4.JNS22203","journal-title":"J Neurosurg"},{"issue":"1","key":"5454_CR39","doi-asserted-by":"publisher","first-page":"166","DOI":"10.1177\/0194599816677522","volume":"156","author":"MJ Sylvester","year":"2017","unstructured":"Sylvester MJ, Shastri DN, Patel VM, Raikundalia MD, Eloy JA, Baredes S, Ying Y-LM (2017) Outcomes of vestibular schwannoma surgery among the elderly. Otolaryngol-Head Neck Surg Off J Am Acad Otolaryngol-Head Neck Surg 156(1):166\u2013172","journal-title":"Otolaryngol-Head Neck Surg Off J Am Acad Otolaryngol-Head Neck Surg"},{"issue":"1","key":"5454_CR40","first-page":"5","volume":"5","author":"MN Tsao","year":"2017","unstructured":"Tsao MN, Sahgal A, Xu W et al (2017) Stereotactic radiosurgery for vestibular schwannoma: International Stereotactic Radiosurgery Society (ISRS) Practice Guideline. J Radiosurgery SBRT 5(1):5\u201324","journal-title":"J Radiosurgery SBRT"},{"issue":"1","key":"5454_CR41","doi-asserted-by":"publisher","first-page":"207","DOI":"10.3171\/2013.6.JNS122433","volume":"120","author":"KM Van Abel","year":"2014","unstructured":"Van Abel KM, Carlson ML, Driscoll CL, Neff BA, Link MJ (2014) Vestibular schwannoma surgery in the elderly: a matched cohort study. J Neurosurg 120(1):207\u2013217","journal-title":"J Neurosurg"},{"issue":"5","key":"5454_CR42","doi-asserted-by":"publisher","first-page":"885","DOI":"10.3171\/2011.6.JNS101963","volume":"115","author":"R van de Langenberg","year":"2011","unstructured":"van de Langenberg R, Hanssens PEJ, Verheul JB, van Overbeeke JJ, Nelemans PJ, Dohmen AJC, de Bondt BJ, Stokroos RJ (2011) Management of large vestibular schwannoma. Part II. Primary Gamma Knife surgery: radiological and clinical aspects. J Neurosurg 115(5):885\u2013893","journal-title":"J Neurosurg"},{"issue":"2","key":"5454_CR43","doi-asserted-by":"publisher","first-page":"389","DOI":"10.1007\/s00701-013-1924-5","volume":"156","author":"T Wangerid","year":"2014","unstructured":"Wangerid T, Bartek J, Svensson M, F\u00f6rander P (2014) Long-term quality of life and tumour control following gamma knife radiosurgery for vestibular schwannoma. Acta Neurochir (Wien) 156(2):389\u2013396","journal-title":"Acta Neurochir (Wien)"},{"issue":"Suppl 1","key":"5454_CR44","doi-asserted-by":"publisher","first-page":"64","DOI":"10.3171\/2016.7.GKS161494","volume":"125","author":"S Watanabe","year":"2016","unstructured":"Watanabe S, Yamamoto M, Kawabe T, Koiso T, Yamamoto T, Matsumura A, Kasuya H (2016) Stereotactic radiosurgery for vestibular schwannomas: average 10-year follow-up results focusing on long-term hearing preservation. J Neurosurg 125(Suppl 1):64\u201372","journal-title":"J Neurosurg"},{"issue":"7","key":"5454_CR45","doi-asserted-by":"publisher","first-page":"1457","DOI":"10.1007\/s00701-019-03951-z","volume":"161","author":"S Watanabe","year":"2019","unstructured":"Watanabe S, Yamamoto M, Kawabe T, Koiso T, Aiyama H, Kasuya H, Barfod BE (2019) Long-term follow-up results of stereotactic radiosurgery for vestibular schwannomas larger than 8 cc. Acta Neurochir (Wien) 161(7):1457\u20131465","journal-title":"Acta Neurochir (Wien)"},{"issue":"1","key":"5454_CR46","doi-asserted-by":"publisher","first-page":"159","DOI":"10.1016\/S1470-2045(18)30659-4","volume":"20","author":"A Wolf","year":"2019","unstructured":"Wolf A, Naylor K, Tam M et al (2019) Risk of radiation-associated intracranial malignancy after stereotactic radiosurgery: a retrospective, multicentre, cohort study. Lancet Oncol 20(1):159\u2013164","journal-title":"Lancet Oncol"},{"key":"5454_CR47","unstructured":"World Health Organization (2021) Ageing and health. https:\/\/www.who.int\/news-room\/fact-sheets\/detail\/ageing-and-health . Accessed Oct 2022"},{"issue":"3","key":"5454_CR48","doi-asserted-by":"publisher","first-page":"801","DOI":"10.3171\/2010.8.JNS10674","volume":"114","author":"H-C Yang","year":"2011","unstructured":"Yang H-C, Kano H, Awan NR, Lunsford LD, Niranjan A, Flickinger JC, Novotny J, Bhatnagar JP, Kondziolka D (2011) Gamma Knife radiosurgery for larger-volume vestibular schwannomas. Clinical article. J Neurosurg 114(3):801\u2013807","journal-title":"J Neurosurg"}],"container-title":["Acta Neurochirurgica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00701-022-05454-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00701-022-05454-w\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00701-022-05454-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,1,14]],"date-time":"2023-01-14T06:04:29Z","timestamp":1673676269000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00701-022-05454-w"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,12,22]]},"references-count":48,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2023,1]]}},"alternative-id":["5454"],"URL":"https:\/\/doi.org\/10.1007\/s00701-022-05454-w","relation":{},"ISSN":["0942-0940"],"issn-type":[{"value":"0942-0940","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,12,22]]},"assertion":[{"value":"30 August 2022","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"7 December 2022","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"22 December 2022","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Each center obtained review board approval for the study and for sharing the de-identified patient database. Due to the retrospective nature of this study, written consent is not mandatory.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"The authors declare that no funds, grants, or other support were received during the preparation of this manuscript. Dr. Lunsford is a shareholder in Elekta AB, the manufacturer of some radiosurgical devices, a consultant for Teledoc Inc.. and a chair for Insightec\u2019s data safety monitoring board. Dr. C. P. Cifarelli has received speaking honoria from Carl Zeiss. Dr. Zacharia is a consultant for Medtronic Inc. and a member of the speaker\u2019s bureau of NICO Corp. and has ownership in Decentramed LLC.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}