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In this single-centre pilot study, we are comparing these two treatment modalities and their effects on PbtO<jats:sub>2<\/jats:sub>.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Methods<\/jats:title>\n            <jats:p>Retrospective case series of patients with DCI who had PbtO<jats:sub>2<\/jats:sub> monitoring as part of their multimodality monitoring and underwent either CA or TBA combined with CA. PbtO<jats:sub>2<\/jats:sub> values were recorded from intra-parenchymal Raumedic NEUROVENT-PTO\u00ae probes. Data were continuously collected and downloaded as second-by-second data. Comparisons were made between pre-angioplasty PbtO<jats:sub>2<\/jats:sub> and post-angioplasty PbtO<jats:sub>2<\/jats:sub> median values (4\u00a0h before angioplasty, 4\u00a0h after and 12\u00a0h after).<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Results<\/jats:title>\n            <jats:p>There were immediate significant improvements in PbtO<jats:sub>2<\/jats:sub> at the start of intervention in both groups. PbtO<jats:sub>2<\/jats:sub> then increased by 13\u00a0mmHg in the CA group and 15\u00a0mmHg in the TBA plus CA group in the first 4\u00a0h post-intervention. This improvement in PbtO<jats:sub>2<\/jats:sub> was sustained for the TBA plus CA group but not the CA group.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusion<\/jats:title>\n            <jats:p>Combined balloon plus chemical angioplasty results in more sustained improvement in brain tissue oxygenation compared with chemical angioplasty alone. Our findings suggest that PbtO<jats:sub>2<\/jats:sub> is a useful tool for monitoring the response to angioplasty in vasospasm.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1007\/s00701-024-06066-2","type":"journal-article","created":{"date-parts":[[2024,4,16]],"date-time":"2024-04-16T20:24:40Z","timestamp":1713299080000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Chemical angioplasty vs. balloon plus chemical angioplasty for delayed cerebral ischemia: a pilot study of PbtO2 outcomes"],"prefix":"10.1007","volume":"166","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7809-7293","authenticated-orcid":false,"given":"Eleanor M.","family":"Moncur","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6199-0090","authenticated-orcid":false,"given":"Claudia L.","family":"Craven","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Selma","family":"Al-Ahmad","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bethany","family":"Jones","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fergus","family":"Robertson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ugan","family":"Reddy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ahmed K.","family":"Toma","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2024,4,16]]},"reference":[{"issue":"5","key":"6066_CR1","doi-asserted-by":"publisher","first-page":"979","DOI":"10.1097\/00006123-199805000-00013","volume":"42","author":"GK Bejjani","year":"1998","unstructured":"Bejjani GK, Bank WO, Olan WJ, Sekhar LN (1998) The efficacy and safety of angioplasty for cerebral vasospasm after subarachnoid hemorrhage. 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