{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,22]],"date-time":"2025-02-22T05:37:45Z","timestamp":1740202665700,"version":"3.37.3"},"reference-count":6,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2024,6,6]],"date-time":"2024-06-06T00:00:00Z","timestamp":1717632000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2024,6,6]],"date-time":"2024-06-06T00:00:00Z","timestamp":1717632000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Acta Neurochir"],"abstract":"<jats:title>Abstract<\/jats:title>\n          <jats:sec>\n            <jats:title>Background<\/jats:title>\n            <jats:p>An ACTH-secreting pituitary adenoma is the most common cause of excessive endogenous glucocorticoid production resulting in Cushing\u2019s Syndrome. A multidisciplinary approach is paramount. Selective adenomectomy is the treatment of choice.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Method<\/jats:title>\n            <jats:p>Endoscopic transnasal transsphenoidal approach to the tumour, along with techniques for resection, are demonstrated.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusion<\/jats:title>\n            <jats:p>Endoscopic transsphenoidal approaches with its magnified view of the pituitary gland allows precise microsurgical dissection during selective adenomectomy. This technique increases the possibility of proving a gross total resection, leading to clinical and biochemical cure in these patients.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1007\/s00701-024-06078-y","type":"journal-article","created":{"date-parts":[[2024,6,6]],"date-time":"2024-06-06T08:02:21Z","timestamp":1717660941000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["HOW I DO IT: Cushing\u2019s disease\u2014selective adenomectomy via an endoscopic transsphenoidal approach"],"prefix":"10.1007","volume":"166","author":[{"given":"N.","family":"Phillips","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.","family":"Nix","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0915-9723","authenticated-orcid":false,"given":"M.","family":"De Santos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2024,6,6]]},"reference":[{"key":"6078_CR1","doi-asserted-by":"publisher","first-page":"847","DOI":"10.1016\/S2213-8587(21)00235-7","volume":"9","author":"M Fleseriu","year":"2021","unstructured":"Fleseriu M, Auchus R, Bancos I, Ben-Shlomo A, Bertherat J, Biermasz NR et al (2021) Consensus on diagnosis and management of Cushing\u2019s disease: a guideline update. Lancet Diabetes Endocrinol 9:847\u2013875","journal-title":"Lancet Diabetes Endocrinol"},{"key":"6078_CR2","doi-asserted-by":"crossref","unstructured":"Hadad G, Bassagasteguy L, Carrau RL, Mataza JC, Kassam A, Snyderman CH et al (2006) A novel reconstructive technique after endoscopic expanded endonasal approaches: vascular pedicle nasoseptal flap. Laryngoscope [Internet] 116:1882\u20136. Available from:\u00a0https:\/\/pubmed.ncbi.nlm.nih.gov\/17003708\/.\u00a0Accessed 5 Oct 2023","DOI":"10.1097\/01.mlg.0000234933.37779.e4"},{"key":"6078_CR3","doi-asserted-by":"crossref","unstructured":"Lonser RR, Nieman L, Oldfield EH (2017) Cushing\u2019s disease: pathobiology, diagnosis, and management. J Neurosurg [Internet] 126:404\u201317. Available from:\u00a0https:\/\/pubmed.ncbi.nlm.nih.gov\/27104844\/. Accessed 5 Oct 2023","DOI":"10.3171\/2016.1.JNS152119"},{"key":"6078_CR4","doi-asserted-by":"crossref","unstructured":"Nix P, Tyagi A, Phillips N (2016) Evolution of a UK endoscopic anterior skull base pituitary service - the first one hundred and twenty-three patients: Our Experience. Clin Otolaryngol [Internet] 41:289\u201393. Available from:\u00a0https:\/\/pubmed.ncbi.nlm.nih.gov\/26243005\/.\u00a0Accessed 5 Oct 2023","DOI":"10.1111\/coa.12514"},{"key":"6078_CR5","doi-asserted-by":"publisher","first-page":"1983","DOI":"10.1007\/s00701-016-2916-z","volume":"158","author":"N Phillips","year":"2016","unstructured":"Phillips N, Nix P (2016) How I do it - endoscopic endonasal approach for pituitary tumour. Acta Neurochir (Wien) [Internet] 158:1983\u20135. https:\/\/doi.org\/10.1007\/s00701-016-2916-z","journal-title":"Acta Neurochir (Wien) [Internet]"},{"key":"6078_CR6","doi-asserted-by":"publisher","first-page":"126","DOI":"10.1016\/j.wneu.2022.03.076","volume":"162","author":"M Sabahi","year":"2022","unstructured":"Sabahi M, Shahbazi T, Maroufi SF, Vidal K, Recinos PF, Kshettry VR et al (2022) MRI\u2013negative cushing\u2019s disease: A review on therapeutic management. World Neurosurg [Internet] 162:126-137.e1. https:\/\/doi.org\/10.1016\/j.wneu.2022.03.076","journal-title":"World Neurosurg [Internet]"}],"container-title":["Acta Neurochirurgica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00701-024-06078-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00701-024-06078-y\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00701-024-06078-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T21:00:26Z","timestamp":1740171626000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00701-024-06078-y"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,6,6]]},"references-count":6,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2024,12]]}},"alternative-id":["6078"],"URL":"https:\/\/doi.org\/10.1007\/s00701-024-06078-y","relation":{},"ISSN":["0942-0940"],"issn-type":[{"type":"electronic","value":"0942-0940"}],"subject":[],"published":{"date-parts":[[2024,6,6]]},"assertion":[{"value":"23 October 2023","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"5 April 2024","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"6 June 2024","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Ethics approval was not required.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval"}},{"value":"Informed consent was obtained from the patient and parent.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to participate"}},{"value":"The authors affirm that the participant and parent has consented to the publishing of their data and photographs.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"We have no potential conflict of interest.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflicts of interest"}}],"article-number":"252"}}