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This database constitutes the largest series of SSCD patients to date.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Objective<\/jats:title>\n            <jats:p>To determine what preoperative factors, if any, contribute to postoperative outcomes and evaluate symptom resolution in a large SSCD patient cohort.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Methods<\/jats:title>\n            <jats:p>A single-institution, retrospective chart review collected patient demographics, intraoperative findings, and pre-and postoperative symptoms. Fisher's exact t-test was performed for unpaired categorical variables, with a significance level of <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.05.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Results<\/jats:title>\n            <jats:p>350 SSCD repairs were performed. The median age was 52\u00a0years (range: 17\u201486\u00a0years,\u2009\u00b1\u20096.4\u00a0years), and the median follow-up duration was 4.6\u00a0months (range: 0.03\u201459.5\u00a0months,\u2009\u00b1\u20096.8\u00a0months). Preoperative hearing loss was significantly associated with female sex (<jats:italic>p<\/jats:italic>\u2009=\u20090.0028). The most reported preoperative symptoms were tinnitus (77.4%), dizziness (74.0%), autophony (66.3%), amplification (63.7%), and disequilibrium (62.6%). Between patients who received unilateral versus bilateral SSCD repair, the greatest postoperative symptomatic resolution was seen in autophony (74.9%, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001), amplification (77.3%, <jats:italic>p<\/jats:italic>\u2009=\u20090.00027), hyperacusis (77.4%, <jats:italic>p<\/jats:italic>\u2009=\u20090.023), hearing (62.9%, <jats:italic>p<\/jats:italic>\u2009=\u20090.0063), and dizziness (54.6%, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001) for patients with unilateral SSCD repair.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusion<\/jats:title>\n            <jats:p>Surgical repair via the middle cranial fossa approach can significantly resolve auditory, vestibular, and neurological symptoms of patients with SSCD. Although this is one of the largest single-institution SSCD studies to date, future multi-institutional, prospective studies would be beneficial to validate these results.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1007\/s00701-024-06115-w","type":"journal-article","created":{"date-parts":[[2024,5,24]],"date-time":"2024-05-24T20:20:53Z","timestamp":1716582053000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Superior semicircular canal dehiscence postoperative outcomes: a case series of 350 repairs"],"prefix":"10.1007","volume":"166","author":[{"given":"Mahlet","family":"Mekonnen","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Meachelle","family":"Lum","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Courtney","family":"Duong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shivam","family":"Rana","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Khashayar","family":"Mozaffari","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gabrielle E. 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